Clinical trials: Activity Restriction
Obesity
Nutritional Restriction and Activity Thermogenesis
These studies will provide us with enormous insight regarding how obese patients adapt energetically during negative energy balance.
- Trial name
- NCT00065338
- Testing
- Exercise and behavior modification
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Exercise
Effects of Low Intensity, High Intensity Eccentric Resistance Training Associated With Blood Flow Restriction
Introduction: studies on resistance training of low intensity associated with blood flow restriction in recent years, although there are still gaps that can be explored in relation to their physiological phenomena when associated…
- Trial name
- oclusion (NCT03601104)
- Testing
- High intensity eccentric training, High intensity eccentric training with BFR, Low intensity eccentric training with BFR
- Where
- Brazil
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Paulista University
Obesity
Sleep Timing on Energy Intake and Energy Expenditure
Studies in healthy young adults have shown that abnormal and undesirable physiological changes are a result of chronic sleep curtailment, with implications on inflammatory status, blood glucose regulation, circulating free fatty…
- Trial name
- NCT05096585
- Testing
- Delayed bedtime sleep restriction, Early wake sleep restriction
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Chronic Obstructive Pulmonary Disease (COPD)
Comparison of Long-term Safety of the Combination Product QVA149A Against Placebo and Standard of Care Treatment in Chronic Obstructive Pulmonary Disease Patients With Moderate to Severe Airflow Limitation
The study will assess the long-term safety of the fixed combination product QVA149 versus placebo and a standard of care treatment (tiotropium) in Chronic Obstructive Pulmonary Disease (COPD) patients with moderate to severe…
- Trial name
- NCT01610037
- Testing
- QVA149, Tiotropium
- Where
- 116 sites in Argentina, Colombia and 15 more
- Volunteers
- 1,215 people
- Sponsor
- Novartis Pharmaceuticals
Pediatric Obesity
Energy Intake and Energy Deficit in Obese Adolescents
The aim of the present study is to compare the effect of two weight loss interventions inducing the same energy deficit but one based on exercise and one using dietary restriction, on appetite control in obese adolescents.
- Trial name
- IDEFIX (NCT03466359)
- Testing
- DEF-EI : Energy restriction induced energy deficit, DEF-EX : Exercise induced energy deficit
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Aging, Mobility Limitation
Evaluating Implementation and Impact of the Adapted Choose to Move (CTM) Program
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Aging, Mobility Limitation, Physical Inactivity, Sedentary Behavior
- Trial name
- CTM (NCT06252259)
- Testing
- Choose to Move
- Where
- Canada
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Preterm Premature Rupture of Membrane
Bed Rest After Preterm Premature Rupture of the Membranes
Antepartum bed rest is widely prescribed after preterm premature rupture of the membranes (PPROM), although its effectiveness to prevent preterm birth has not been demonstrated.
- Trial name
- NCT03814278
- Testing
- complete bed rest, activity restriction
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar Lisboa Norte
Men, Diet Modification
Dietary Guide in Active Older Adult Men
The present study aimed to determine the effects of negative-calorie diet supplemented with exercise, on weight loss and lipid profile, and to compare its efficiency with low-calorie diet with exercise among elderly adult men…
- Conditions
- Men, Diet Modification, Obesity, Overweight
- Trial name
- NCT03082807
- Testing
- NCDsport, LCDsport
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- P.L.Shupik National Medical Academy of Post-Graduate Education
Intentional Self-Harm by Other Specified Means
Comparison of Lethal Means Counseling and an Active Control Condition, With and Without Provision of Gun Locks
In 2013, the National Guard reported a suicide rate that was substantially higher than both the general population and the active duty component of the United States military.
- Trial name
- NCT03375099
- Testing
- Lethal Means Counseling, Health and Stress Reduction
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Southern Mississippi
Neck Injuries
Evaluation of Comfort in a Spinal Collar
This is an observational study which aims to assess the comfort of a spinal collar in patients who have them fitted as part of their clinical care due to neck injury.
- Trial name
- NCT04066686
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Imperial College Healthcare NHS Trust
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Phase I Randomized Controlled Trial of Functional Resistance Training in Older Cancer Survivors: The ACES Trial
The study will assess the feasibility and preliminary efficacy of live, online supervised group functional resistance training in older cancer survivors who may have difficulty with independent functioning.
- Conditions
- Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm, Cancer, Functional Limitation
- Trial name
- ACES (NCT07606313)
- Testing
- Functional Resistance Training, Stretching, Delayed Functional Resistance Training
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- OHSU Knight Cancer Institute
Aging, Cognitive Decline
Augmented Reality Treadmill Walking for Cognitive and Physical Health in Older Adults
This study evaluated the feasibility and health effects of using augmented reality (AR) treadmill walking in older adults. Sixty community-dwelling adults aged 65 to 80 years were randomly assigned to either an AR treadmill group…
- Conditions
- Aging, Cognitive Decline, Sarcopenia, Mobility Limitation
- Trial name
- ART-Walk (NCT07074613)
- Testing
- Traditional Treadmill Walking, JOHNSON 8.1T treadmill with Passport AR system
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan College of Performing Arts
Preterm Birth
Activity Restriction for Women With Arrested Preterm Labor
to test the hypothesis that activity restriction in women with singleton gestations and with arrested PTL would reduce the rate of PTB.
- Trial name
- NCT03501030
- Testing
- Activity restriction
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Federico II University
Osteoarthritis, Pain
A Single-Blind Placebo Run-in Study of Duloxetine for Activity-Limiting Osteoarthritis Pain
This will be a single-blind, placebo-run-in trial. Subjects will be informed that they may receive duloxetine or placebo during the course of the trial. All subjects will, in fact, receive placebo for the first two weeks.
- Trial name
- NCT00609557
- Testing
- duloxetine
- Volunteers
- 25 people
- Sponsor
- University of Washington
Elbow Fracture, Limitation, Mobility
Graded Motor Imagery in Elbow Limitation
This randomized-controlled trial aims to investigate the efficacy of Graded Motor Imagery (GMI) on function, pain, and range of motion (ROM) in patients with a posttraumatic stiff elbow.
- Conditions
- Elbow Fracture, Limitation, Mobility, Pain, Postoperative, Upper Extremity Problem
- Trial name
- NCT03969277
- Testing
- Graded Motor Imagery, Standard Rehabilitation, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Unilateral Cerebral Palsy
Sensitivity of an Upper Limb Motion Analysis Protocol to Changes in Kinematics and Muscle Activity After Constraint Induced Therapy in Children With Hemiplegia
In France, Cerebral Palsy (CP) affects 1 in 450 births. It results from lesions of the brain, before, during, or shortly after birth. These non-progressive lesions cause muscle impairments, responsible for activity limitations.
- Trial name
- MouvsupTCIHemi (NCT03099993)
- Testing
- Measurement of maximal forces of elbow pronosupination and flexion-extension
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Aging, Mobility Limitation
Choose to Move - Next Steps: Can 'Booster Sessions' Sustain Health Benefits of an Effective, Scaled-up, Health Promotion Program?
One-third of Canadians will be older adults (>65y) by 2050. Thus, healthy aging is a public health priority. Many older adult health promoting interventions have been implemented, yet few were scaled-up and sustained.
- Conditions
- Aging, Mobility Limitation, Sedentary Behavior, Loneliness
- Trial name
- CTM-NS (NCT04592614)
- Testing
- Choose to Move - Next Steps
- Where
- Canada
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Muscle Weakness
Promoting Seniors' Health With Home Care Aides
This study aims to test whether a safe physical activity program with a built-in motivational enhancement component, performed in a seated position, preserves the function and well-being of older home care clients.
- Trial name
- NCT03301116
- Testing
- Healthy Moves for Aging Well (Healthy Moves), Active Mind for Aging Well (Active Mind)
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- University of Illinois at Chicago
Osteoarthritis, Knee
Effect of Low Intensity Training Combined With Partial Restriction of Blood Flow in Individuals With Knee Osteoarthritis
Osteoarthritis (OA) is a chronic degenerative infection that presents clinical features such as pain and limited range of motion.
- Trial name
- NCT04819672
- Testing
- Low Intensity Training associated with Partial Blood Flow
- Volunteers
- 66 people
- Sponsor
- Universidade Federal do Ceara
Chronic Obstructive Pulmonary Disease
Efficacy and Safety Study of Indacaterol Maleate/Glycopyrronium Bromide in Chronic Obstructive Pulmonary Disease (COPD) Patients.
The purpose of this study is to demonstrate that the efficacy of the combination product QVA149 is similar to the efficacy of the combination product umeclidinium/vilanterol on a pre-specified endpoint of FEV1 AUC0-24h while…
- Trial name
- NCT02487498
- Testing
- QVA149, Umeclidinium/vilanterol
- Where
- 53 sites in United States
- Volunteers
- 355 people
- Sponsor
- Novartis Pharmaceuticals