Clinical trials: Activities of Daily Living
Prostatic Cancer, Castration-Resistant
Study to Compare the Effects of Drug Darolutamide and Drug Enzalutamide on Physical Function, Including Balance and Daily Activity, in Patients With Castration-resistant Prostate Cancer (CRPC)
Researchers in this study want to compare the effects of drug darolutamide and drug enzalutamide on physical function, including balance and daily activity, in patients with castration-resistant prostate cancer (CRPC).
- Trial name
- DaroAcT (NCT04157088)
- Testing
- Darolutamide (Nubeqa, BAY1841788), Enzalutamide
- Where
- 7 sites in United States
- Volunteers
- 30 people
- Sponsor
- Bayer
Laminectomy
Esmolol Infusion During Laminectomy: Effect on Quality of Recovery
The purpose of this study is to evaluate the effects of esmolol, a drug which is commonly administered during surgery to help control blood pressure and heart rate, on postoperative pain levels and requirements for pain…
- Trial name
- NCT01179113
- Testing
- Esmolol, Saline
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Cedars-Sinai Medical Center
Pain, Dementia
Music Based Caregiving in Patients With Pain and Dementia
The main objective of this study is to evaluate the pain-relieving effect of a well-characterized non-pharmacological treatment program, music-based caregiving (MBC), to patients in nursing homes with dementia and pain.
- Conditions
- Pain, Dementia, Music, Activity, Motor
- Trial name
- NCT04229446
- Testing
- Music based caregiving
- Where
- 2 sites in Norway
- Volunteers
- 276 people
- Sponsor
- Oslo University Hospital
Frailty, Sarcopenia
FrAilty Care and wEll-funcTion in Community Dwelling Older Adults
This study is looking at whether older people could benefit from an online monitoring platform to support their individual ambitions to maintain or improve functional ability.
- Conditions
- Frailty, Sarcopenia, Aging
- Trial name
- FACET (NCT03707145)
- Testing
- Consultation, Online Support, Empowered
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Aberystwyth University
Functional Limitation
Home-based Exercise Via a Telecommunications System
This study is investigating the effects of a home-based resistance exercise program, administered via an interactive telecommunications system, in functionally limited older veterans.
- Trial name
- NCT00248781
- Testing
- Telecommunications system, attention control
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Neurologic Disorders
The Impact of Environmental Controls on Mental Health
Within the UK there are over 15 million people who live with at least one long term condition. Of these people, over 4 million suffer from mental health problems.
- Trial name
- EC-MH (NCT07049419)
- Testing
- Provision of an environmental control system
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- NHS Lothian
Alzheimer Disease, Dementia
Efficacy of Caregiver Training Program in Enhancing Caregiver and Patient Outcomes
As part of Phase II of the NIH SBIR grant, the study will conduct a randomized controlled clinical trial in which the MapHabit system (MHS) will offer a caregiver training product in adjunct.
- Conditions
- Alzheimer Disease, Dementia, Caregiver Burden, Assistive Technology
- Trial name
- NCT05527405
- Testing
- The MapHabit System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- MapHabit, Inc.
Parkinson Disease Psychosis
Open-Label Study With Pimavanserin on Activities of Daily Living in Subjects With Parkinson's Disease Psychosis
To assess the effect of pimavanserin on the activities of daily living in subjects with Parkinson's Disease Psychosis
- Trial name
- NCT04292223
- Testing
- Pimavanserin
- Where
- 18 sites in United States
- Volunteers
- 29 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Lower Extremity Amputation
Adherence and Perspiration While Wearing Lower Limb Prostheses
Individuals with lower limb amputation often complain about uncomfortable residual limb skin temperatures and the accumulation of sweat inside their prostheses.
- Trial name
- NCT03900845
- Testing
- Dynamic Air Exchange - Rising Edge Design (DAE-RED), Perforated elastomeric liner, As-prescribed prosthesis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Ankle Osteoarthritis
Cryoneurolysis for Improvements in Pain, ADL and QOL in Patients With Ankle Osteoarthritis
This will be an open-label trial to describe the effects of cryoneurolysis with iovera° on symptom relief in patients with painful Kellgren-Lawrence (KL) grade 2-4 ankle osteoarthritis (OA).
- Trial name
- NCT03567187
- Testing
- iovera
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Kansas Medical Center
Snake Envenomation
The Efficacy of Crotaline Fab Antivenom for Copperhead Snake Envenomations
Most patients bitten by copperhead snakes do not currently receive antivenom. Some snakebite victims have long term problems with the function of the limb that was bitten.
- Trial name
- NCT00303303
- Testing
- Crotaline Polyvalent Immune Fab (ovine) (active initial and maintenance therapy)
- Where
- 4 sites in United States
- Volunteers
- 13 people
- Sponsor
- Wake Forest University Health Sciences
Heart Disease (Coronary Artery Disease, Ischemic Heart Disease, Hypertensive Heart Disease), Uncontrolled Diabetes (HBA1c ≥ 10)
Piloting the IPROACTIF Program to Preserve Functioning and Prevent Cognitive Decline
Conduct a pilot randomized control to assess the preliminary efficacy of IPROACTIF, an occupational therapist-delivered primary care intervention for aging and chronic disease management.
- Trial name
- NCT04682977
- Testing
- IPROACTIF (Integrated PRimary Care and Occupational Therapy for Aging and Chronic Disease Treatment to preserve Independence and Functioning), Usual primary care services
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Illinois at Chicago
Activities of Daily Living, Caregivers
Functional Recovery and Caregiver Burden Following Surgery in the Elderly
The purpose of this study is to assess the functional recovery of older ambulatory surgical patients and the impact of the current model of care on the caregivers of these patients.
- Conditions
- Activities of Daily Living, Caregivers, Ambulatory Surgical Procedures
- Trial name
- FOCUS (NCT01382251)
- Where
- Canada
- Volunteers
- 123 people
- Sponsor
- Ottawa Hospital Research Institute
Frailty, Frail Elderly
Synergizing Home Health Rehabilitation Therapy
The objective of this project is to pilot test an ADL (activities of daily living)-enhanced program as an adjuvant therapy to usual home health rehabilitation to improve patient outcomes.
- Conditions
- Frailty, Frail Elderly, Occupational Therapy, Activities of Daily Living
- Trial name
- NCT05411393
- Testing
- ADL-enhanced program, Usual home health rehabilitation therapy
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Florida
Stroke
Effects of Device-assisted Practice of ADL on Arm/Hand Recovery in Individuals With Moderate to Severe Stroke
A large number of post-stroke survivors cannot functionally use their paretic upper extremity (UE). This study therefore investigates effects of device-assisted practice of activities of daily living (ADL) in a close-to-normal…
- Trial name
- NCT04077073
- Testing
- ReIn-Hand, Robot
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Northwestern University
Non-inflammatory Arthritis
Does Implant Design Improve Postoperative Flexion?
This study will evaluate whether design features of one implant design allows more knee bend than the other. Patients will have 1 design in the left knee and 1 design in their right knee.
- Trial name
- NCT00380861
- Testing
- Total knee replacement using the PFC Sigma RPF knee implant., Total knee replacement using the PFC Sigma RP knee implant
- Where
- 4 sites in United States
- Volunteers
- 93 people
- Sponsor
- DePuy Orthopaedics
Aging, Healthy
ACTIVE: Advanced Cognitive Training for Independent and Vital Elderly
The purpose of the ACTIVE study was to test if cognitive training interventions could maintain functional independence in elders by improving basic mental abilities, with follow-up assessments through five years.
- Trial name
- ACTIVE (NCT00298558)
- Testing
- Cognitive Training
- Where
- 7 sites in United States
- Volunteers
- 2,832 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Compression Fracture of Vertebral Body, Osteoporosis
Evaluation of Outcomes for Quality of Life and Activities of Daily Living for BKP in the Treatment of VCFs
The study objective is to collect and report 12-month outcomes pertaining to activities of daily living, quality of life, and safety parameters in a Medicare population to be treated with balloon kyphoplasty in the treatment of…
- Conditions
- Compression Fracture of Vertebral Body, Osteoporosis, Cancer
- Trial name
- EVOLVE (NCT01871519)
- Testing
- Balloon kyphoplasty
- Where
- 25 sites in United States
- Volunteers
- 354 people
- Sponsor
- Medtronic Spinal and Biologics
Eating Behavior, Eating Habit
Young Adult Eating Habits
Most individuals with obesity become so before age 35 and adolescent's unhealthy dietary patterns, specifically high intake of ultra-processed foods and poor overall diet quality, may contribute to energy overconsumption and…
- Trial name
- YAEH (NCT05550818)
- Testing
- High Ultra Processed Food Diet, No Ultra Processed Food Diet
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Physical Disability, Cognitive Impairment
Improving Aging in Place in Subsidized Housing
This pilot study will evaluate the feasibility and preliminary effectiveness of an adapted version of the Function Focused Care intervention, delivered by telephone, for improving aging in place for older adults living in…
- Conditions
- Physical Disability, Cognitive Impairment, Physical Activity
- Trial name
- NCT04212442
- Testing
- Independent Living Program for Affordable Housing.
- Where
- 13 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania