Clinical trials: Acne
Acne Vulgaris
A Pilot, Multi-Center, Patient Preference Study Comparing Two Clindamycin/Benzoyl Peroxide Gels.
Evaluate patient preference factors comparing two clindamycin/benzoyl peroxide gels. One dispensed in a pump presentation, the other in a tube presentation.
- Trial name
- NCT00377000
- Testing
- clindamycin 1% / benzoyl peroxide 5% gel pump, clindamycin 1% / benzoyl peroxide 5% tube
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sanofi
Acne Vulgaris
Comparison of Two Salicylic Acid Formulations
This study is a split face, paired-comparison, pilot study of at least 10 subjects to complete. Participants in this study will be patients seen at Children's Memorial Hospital, who are clinically diagnosed with mild to moderate…
- Trial name
- NCT00848744
- Testing
- Formulation A, Formulation B
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Hidradenitis Suppurativa (Acne Inversa)
Efficacy, Safety, and Pharmacokinetics Study of CJM112 in Hidradenitis Suppurativa Patients
This is a randomized, double blind, multicenter study in patients with moderate to severe chronic hidradenitis suppurativa in parallel groups, to determine the efficacy and safety of multiple doses of CJM112 in comparison to…
- Trial name
- NCT02421172
- Testing
- CJM112
- Where
- 16 sites in United States, Denmark and 3 more
- Volunteers
- 66 people
- Sponsor
- Novartis Pharmaceuticals
Cosmetic Acne
Effect of a Facial Cream Containing Cannabidiol and Hemp Oil on Skin Hydration and Acne-prone Skin
This research seeks to evaluate the short (i.e., after single application) and long-term (i.e., after periodic application) hydrating effect of a topical preparation containing CBD and hemp oil on facial skin as well as the…
- Trial name
- Dahlia (NCT04045119)
- Testing
- Topical Moisturizer
- Where
- Colombia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Avicanna Inc
Acne
An Open Label Trial to Assess the Safety and Efficacy of Oral R115866 in the Treatment Facial Acne
This study is looking at a new oral drug to treat acne. All patients in the study will get active drug, there is no placebo arm.
- Trial name
- NCT00725439
- Testing
- Talarozole
- Where
- 3 sites in Belgium, Netherlands
- Volunteers
- 16 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris
Two-week Study to Compare the Tolerance and Irritation Potential of Two Combination Topical Gel Acne Medications
This is a single-blind (blinded expert grader), randomized, half-face study being conducted at one clinical site. On 1 side of the face, the subject will apply 1 of the 2 test products, antibiotic and benzoyl peroxide or benzoyl…
- Trial name
- NCT00926367
- Testing
- Clindamycin and benzoyl peroxide, benzoyl peroxide 2.5% and adapalene 0.1% gel
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris
A Pilot Study of the Effects of Isotretinoin on Cognition, Learning and Memory
This prospective study tested the effects of isotretinoin in a cohort of patients receiving standard therapy for acne vulgaris. Subjects completed questionnaires and standardised computer based cognitive testing using CANTAB to…
- Trial name
- NCT01404130
- Testing
- Isotretinoin
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Aberdeen
Acne Vulgaris
8 Week Study to Evaluate and Compare the Efficacy and Tolerability of MAXCLARITY II and MURAD To Treat Acne
One of the main success factors in acne therapy is user compliance with treatment, product cost, availability and ease of use. Poor compliance may translate into decreased efficacy (either not improving symptoms well enough or…
- Trial name
- NCT02524665
- Testing
- MAXCLARITY II (2.5% BPO) Foam Cleanser, MAXCLARITY II (2.5% BPO) Foam Treatment, MAXCLARITY II (0.5% Salicylic Acid) Toner Foam
- Volunteers
- 20 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris
Study Comparing Test to Aczone 7.5% and Both to a Placebo Control in the Treatment of Acne Vulgaris
To evaluate the therapeutic effect of DPSG and Placebo gel in the treatment of acne vulgaris.
- Trial name
- NCT03132194
- Testing
- DPSG 7.5%, Aczone
- Volunteers
- 1,125 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne
Topical Application of Engineered Lactobacillus Reuteri With a Zinc Sulfate-Tannic Acid MPN Coating for Acne
A growing body of evidence suggests that the development and progression of acne are closely linked to an imbalance in the skin's microbial community.
- Trial name
- NCT07366229
- Testing
- MPN-coated engineered Lactobacillus reuteri cream, Plain Lactobacillus reuteri cream, Petrolatum-glycerin cream
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Shenzhen People's Hospital
Acne Scars - Atrophic, Wound Healing
Effectiveness of a rhGM-CSF-containing Gel on Promoting Recovery After 1927-nm Fractional Thulium Fiber Laser Treatment of Atrophic Acne Scars.
Atrophic acne scars (AAS) is one of the most common skin sequelae following acne vulgaris. Fractional laser has shown great therapeutic potential in recent years, while there is no standard of wound care after laser resurfacing.
- Trial name
- NCT07305675
- Testing
- rhGM-CSF-containing gel, 1927-nm TFL
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Acne Vulgaris
Double-blinded, Vehicle Controlled Study to Evaluate Efficacy & Tolerance of Bakuchiol and Ethyl Linoleate on Acne
Subjects will be assigned to a active cream or vehicle to compare the cosmetic effects. This will take place over a 12 week period.
- Trial name
- NCT05069272
- Testing
- Bakuchiol and Ethyl Linoleate, Vehicle
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ratan K. Chaudhuri
Acne
Plant-based Dietary Intervention for Treatment of Acne
The purpose of this study is to determine if a low-fat, vegan diet affects the number of acne lesions, acne severity, and acne extent.
- Trial name
- NCT00900939
- Testing
- Low-fat, vegan diet, Control
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Physicians Committee for Responsible Medicine
Acne Vulgaris
A Safety and Efficacy Study of Dapsone Gel in Patients With Acne Vulgaris
This study will assess the safety and efficacy of dapsone gel versus vehicle control in patients with acne vulgaris.
- Trial name
- NCT01974141
- Testing
- Dapsone Gel, Dapsone Gel Vehicle
- Where
- 2 sites in United States, Canada
- Volunteers
- 2,102 people
- Sponsor
- Almirall, S.A.
Acne Vulgaris
Photodynamic Therapy (PDT) With Methyl Aminolevulinate (MAL) Cream in Moderate to Severe Acne
This multicenter study will be divided into 2 phases. The first phase will be an open label, dose-escalation phase, while the second will be a blinded, randomized, vehicle-controlled, parallel-group, dose-response phase.
- Trial name
- NCT00594425
- Testing
- Methyl aminolevulinate (MAL) PDT
- Where
- 14 sites in United States
- Volunteers
- 150 people
- Sponsor
- Photocure
Acne Vulgaris
Non-cutting Laser Therapy in the Treatment of Acne
The purpose of this research project is to study the effect of non-ablative (non-cutting) laser therapy, a technique that uses laser energy to try to improve the appearance of the skin.
- Trial name
- NCT00113425
- Testing
- V-Beam laser, Candela Corp., 595 nm wavelength
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Michigan
Atrophic Acne Scar
SkinPen Efficacy on Acne Scars on the Face and/or Back
This single-center, clinical trial will take place over a 90 day course followed by 1-month and 6-month post treatment visits to assess the efficacy and tolerability of the SkinPen device when used on both men and women on the…
- Trial name
- NCT02646917
- Testing
- Aesthetic Microneedling Treatment
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Bellus Medical, LLC
Acne, Acne Vulgaris
A Clinical Trial Examining the Efficacy of a Novel Acne Treatment Serum
This single-group, open-label clinical trial examines the efficacy of Cool as a Cucumber's Acne Treatment Serum in adults with acne-prone skin.
- Conditions
- Acne, Acne Vulgaris, Skin Health
- Trial name
- NCT07752368
- Testing
- Acne Treatment Serum
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Parea INC dba Cool as a Cucumber
NODULOCYSTIC ACNE
Finasteride Treatment of Severe Nodulocystic Acne
Double-blind, randomized, placebo-controlled, dose-ranging study to evaluate the efficacy and safety of once weekly, high dose oral finasteride compared to placebo for the treatment of severe nodulocystic acne in male subjects.
- Trial name
- NCT02502669
- Testing
- Finasteride 23.5 mg tablets, Finasteride 33.5 mg tablets
- Where
- 25 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Elorac, Inc.
Acne
A Pilot Clinical Trial Investigating the Effect of Cutaneous Cooling on Sebum Production
To evaluate the safety and feasibility of reducing human sebum production using the ZELTIQ System.
- Trial name
- NCT01686841
- Testing
- The Zeltiq System
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics