Clinical trials: Acne
Acne Vulgaris
Efficacy and Tolerability Evaluation of a Novel Dermo-cosmetic Product for Mild-to-moderate Acne
The goal of this non-interventional, observational study is to evaluate the real-world efficacy and tolerance of a novel dermocosmetic cream containing 15% Azelaic acid and a complex of active ingredients (α-AZ cream) in patients…
- Trial name
- NCT07759505
- Where
- Romania
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- ISISPHARMA
Acne Vulgaris
A Pilot, Multi-Center, Patient Preference Study Comparing Two Clindamycin/Benzoyl Peroxide Gels.
Evaluate patient preference factors comparing two clindamycin/benzoyl peroxide gels. One dispensed in a pump presentation, the other in a tube presentation.
- Trial name
- NCT00377000
- Testing
- clindamycin 1% / benzoyl peroxide 5% gel pump, clindamycin 1% / benzoyl peroxide 5% tube
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sanofi
Atrophic Acne Scar
A Study to Evaluate the Efficacy of ELAPR002f in Females and Males With Atrophic Acne Scars
The study is designed to evaluate the efficacy of two formulations of a cross-linked tropoelastin matrix given the product codes ELAPR002f (collectively referred to as ELAPR or ELAPR002) for the treatment of rolling atrophic acne…
- Trial name
- NCT03056235
- Testing
- ELAPR002f, Saline
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Elastagen Pty Ltd
Acne Vulgaris
Study Comparing Acne in Patients Taking Oral Minocycline to Patients Taking Minocycline Plus Topical Tretinoin
The use of oral antibiotics alone to treat inflammatory acne provides little to no long term therapeutic benefit. Acne relapse rates can be reduced by using topical tretinoin 0.01% in conjunction with minocycline, thereby…
- Trial name
- NCT00240513
- Testing
- Minocycline, Minocycline plus tretinoin
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Derm Research @ 888 Inc.
Acne Scars
Effect of Subcision and Suction on Acne Scars
The primary objective of this study is to determine whether the use of standard treatment in conjunction with suction will improve acne scars compared to a standard treatment alone.
- Trial name
- NCT01696513
- Testing
- Suction, Subcision
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Acne Vulgaris
A Study to Evaluate the Irritation Potential of Tazarotene Foam on Skin in Healthy Volunteers
The purpose of this study is to evaluate the irritation level of tazarotene foam after 21 days of exposure on the skin of healthy volunteers.
- Trial name
- NCT01112787
- Testing
- Tazarotene Foam, Vehicle Foam, Sodium Laural Sulfate
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Acne
Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne
This is a 4-part study. Part A will be a randomized, double-blind, placebo-controlled investigation of single ascending doses (SAD) to assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) biomarkers of…
- Trial name
- NCT06989840
- Testing
- TVB-3567
- Where
- 6 sites in United States, Australia
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Sagimet Biosciences Inc.
Acne Vulgaris
A Study to Determine Bioequivalence of Isotretinoin in Healthy Male Subjects Under Fed Condition
This is an open-label, crossover, randomized, single dose, three treatments, three periods and six sequences, single dosage, balanced study to determine Bioequivalence of Isotretinoin.
- Trial name
- NCT02498288
- Testing
- Isotretinoin: Reference Medication 1, Isotretinoin: Reference Medication 2, Isotretinoin: Test Medication
- Where
- Mexico
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Atrophic Acne Scar
Straberi Microneedling For Atrophic Acne
This pilot study will expand knowledge and application needling using the Straberi microneedling device for the improvement of Atrophic Acne Scarring
- Trial name
- SAA (NCT04740268)
- Testing
- Straberi
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universal Skincare Institute
Acne Vulgaris
Profiles Analysis of Genome Wide Association Study (GWAS) in Acne Vulgaris in Indonesia.
This study is a series of descriptive-analytic studies on genomic variants in the facial skin of patients with AV at the Dermatology and Venereology Polyclinic by determining the genetic profile by GWAS examination in AVB and…
- Trial name
- NCT06501560
- Testing
- GWAS
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Acne Cystic, Diet, Healthy
Effect of Different Diets on Isotretinoin Users to Serum Lipid Levels
This research was planned to prevent secondary hyperlipidemia, which may occur due to isotretinoin used in the treatment of severe acne, with diet. There will be three different groups and followed for 12 weeks.
- Trial name
- NCT06250673
- Testing
- Diet experiment
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Igdir University
Acne Vulgaris
Assessment of Serum Catestatin Level in Acne Vulgaris Patients
Acne vulgaris is a persistent inflammatory condition of the pilosebaceous unit, affecting 85% of people between the ages of 12 and 24, it is regarded as one of the most common diseases in teenagers and young adults.
- Trial name
- NCT07054398
- Testing
- Isotretinoin
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aswan University
Acne
Comparison of Efficacy of Azithromycin and Levamisole Versus of Azithromycin in in the Treatment of Acne
Different immunologic mechanisms contribute to development of inflammation in acne vulgaris and immunologic effect of levamisole has been demonstrated.
- Trial name
- NCT01348321
- Testing
- Levamisole
- Where
- Iran
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Ahvaz Jundishapur University of Medical Sciences
Acne Vulgaris
The Efficacy of an Oral Probiotic Associated With a Fixed Combination of Benzoyl Peroxide and Adapalene in the Treatment of Acne
Objective: Clinical trial carried out to evaluate the superiority of efficacy of a treatment regimen with an oral probiotic associated with a fixed combination of 0.1% adapalene and 2.5% benzoyl peroxide compared to an oral…
- Trial name
- NCT05216289
- Testing
- Probiac
- Where
- Brazil
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Hyperpigmentation
Efficacy and Tolerability of the Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins
The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to…
- Trial name
- NCT06268496
- Testing
- serum formula 2039125 03
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Acne Vulgaris
A Study to Evaluate the Potential of Tazarotene Foam to Cause a Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers
The purpose of this study is to evaluate the potential of Tazarotene Foam to induce a phototoxic reaction when exposed to UV and VIS light on skin of healthy volunteers.
- Trial name
- NCT01115322
- Testing
- Tazarotene Foam without irradiation, Tazarotene Foam with UVA and UVB irradiation, Tazarotene Foam with UVA, UVB, and visible light
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Acne Scars - Mixed Atrophic and Hypertrophic, Hyperpigmentation
Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color
The investigators aim to investigate the efficacy and tolerability of a hybrid non-ablative/ablative laser for acne scarring in skin of color.
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Hyperpigmentation, Laser-Induced Hyperpigmentation
- Trial name
- NCT05362929
- Testing
- Sciton Halo
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Acne
Safety and Efficacy of Skin Cleanser Contained Roselle Extract in Acne
Skin cleanser for daily used is essential and one of the most common questions asked by acne patients. There are studies reported beneficial effects of cleansers in acne treatment.
- Trial name
- NCT00701480
- Testing
- skin cleanser contained Hibiscus sabdariffa extract, marketed skin cleanser
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Thammasat University
NODULOCYSTIC ACNE
Finasteride Treatment of Severe Nodulocystic Acne
Double-blind, randomized, placebo-controlled, dose-ranging study to evaluate the efficacy and safety of once weekly, high dose oral finasteride compared to placebo for the treatment of severe nodulocystic acne in male subjects.
- Trial name
- NCT02502669
- Testing
- Finasteride 23.5 mg tablets, Finasteride 33.5 mg tablets
- Where
- 25 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Elorac, Inc.
Acne
Clinical Study for the Evaluation of P-3075 Cream on Acne Treatment
Primary end point of the study is the clinical and non-invasive instrumental evaluation of the activity of P-3075 cream on subjects with acne: 20 subjects with a mild/moderate grade and 20 subjects with a moderately severe/severe…
- Trial name
- ANTI-ACNE (NCT01948570)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Derming SRL