Clinical trials: Achilles Tendon Injury
Muscle Strain, Lower Leg, Muscle Strained Thigh
Cellular Mechanisms Involved in Muscle Pathology
The overall purpose of this proposed study is the understanding of cellular mechanisms involved in the pathologic fatty degeneration of muscle.
- Conditions
- Muscle Strain, Lower Leg, Muscle Strained Thigh, Achilles Tendon; Laceration, Fatty Degeneration
- Trial name
- NCT05798962
- Testing
- Biopsies
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Spondyloarthropathy, Tendinopathy
Cartography and Quantitative Characterization of Achilles Tendon Fibrocartilage by TE = 0ms Imaging at 3T MRI
The purpose of this study is to accurately map calcaneal fibrocartilage using TE = 0 ms imaging, and then apply measurements of our control population to SpA patients with peripheral enthesis study using the calcaneal tendon as a…
- Trial name
- SILENZ (NCT03287596)
- Testing
- MRI ZTE2 sequence
- Where
- France
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Tendinopathy, Chronic Pain
Managing Chronic Tendon Pain by Metformin
The purpose of the current exploratory clinical trial is to determine the effect of oral ingestion of metformin (OIM) in non-diabetic patients with chronic Achilles tendon pain.
- Conditions
- Tendinopathy, Chronic Pain, Achilles Tendinopathy
- Trial name
- NCT06100822
- Testing
- Metformin
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- James Wang
Achilles Tendon Rupture, Achilles Tendon Injury
Endoscopic FHL Transfer for Acute Achilles Tendon Rupture
This observational study aims to evaluate the outcome of endoscopic flexor hallucis longus transfer (FHLt) in patients with acute Achilles tendon rupture (AATR).
- Conditions
- Achilles Tendon Rupture, Achilles Tendon Injury, Achilles Tendon Surgery, Flexor Hallucis Longus
- Trial name
- NCT06641401
- Testing
- Endoscopic Flexor Hallucis Longus transfer for Acute Achilles tendon rupture
- Where
- Greece
- Volunteers
- 28 people
- Sponsor
- Aristotle University Of Thessaloniki
Tendinopathy
Identification and Treatment of Early Tendinopathy in Elite Athletes
Tendon injuries represent a significant problem in elite athletes. The understanding of the pathophysiology of tendinopathy is very sparse, and especially the early events in tendinopathy are unknown.
- Trial name
- NCT03642392
- Testing
- Identification and treatment of early tendinopathy
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Rotator Cuff Tear, Lateral Epicondylitis
Impact of Autologous Pure Platelet-rich Plasma in the Treatment of Tendon Disease
This is a randomized parallel controlled double-blind phase 2 clinical study.All subjects are recruited from the patients of rotator cuff tear, lateral epicondylitis or chronic achilles tendonitis.
- Conditions
- Rotator Cuff Tear, Lateral Epicondylitis, Achilles Tendinitis
- Trial name
- NCT03300531
- Testing
- Ultrasound-guided pure platelet-rich-plasma (P-PRP) injection, Ultrasound-guided platelet-rich-plasma (PRP) injection, Ultrasound-guided Compound betamethasone injection
- Volunteers
- 540 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Tendinopathy, Achilles Tendon
Plantaris Release for Non-insertional Achilles Tendinopathy
The plantaris tendon is recognised as an important factor in non-insertional Achilles tendinopathy (NIAT). A biomechanical study found the plantaris tendon is stiffer and stronger than the Achilles tendon (AT), thus reducing its…
- Trial name
- NCT02775201
- Testing
- Plantaris release under ultrasound guidance, Plantaris excision surgically
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- Fortius Clinic
Achilles Tendon, Rupture
Ultrasonographic Guided Treatment of Acute Achilles Tendon Rupture. Evaluation of Two Novel Ultrasonographic Measurements
With this project the investigators wish to: 1. Test the reproducibility of Amlang's ultrasound classification by examining the intra- and inter-rater reliability. 2.
- Conditions
- Achilles Tendon, Rupture, Ultrasound
- Trial name
- NCT02062567
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Hvidovre University Hospital
Achilles Tendon Rupture
Operative Versus Non-operative Treatment of Achilles Tendon Rupture
This study is intended to determine whether the optimal treatment of acute Achilles tendon ruptures is surgical repair or functional bracing.
- Trial name
- NCT00284648
- Testing
- Surgical repair Achilles tendon rupture, Non-surgical repair Achilles tendon rupture
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Fowler Kennedy Sport Medicine Clinic
Achilles Tendon Rupture
Achilles Tendon Rupture Patient Outcomes at 12 Months
Achilles tendon rupture is a common injury that can significantly impact strength, function, and quality of life. While non-surgical management using structured rehabilitation protocols such as the Swansea Morriston Achilles…
- Trial name
- ATR-12 (NCT07391553)
- Testing
- Non-Surgical Management Using the SMART Protocol
- Where
- 2 sites in United Kingdom
- Volunteers
- 115 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Achilles Tendinopathy
Efficacy of Percutaneous Electrolysis in the Treatment of Achilles Tendinopathy
Achilles tendinopathy (AT) is one of the most reported myotendinous pathologies due to overuse in the literature. In the general adult population, its incidence is 2.35 cases per 1,000 patients, with no difference between men and…
- Trial name
- NCT05301959
- Testing
- low intensity percutaneous musculoskeletal electrolysis, Silbernagel protocol
- Where
- Argentina
- Volunteers
- 102 people
- Sponsor
- Maimonides University
Achilles Tendinopathy, Eccentric Exercise
Pilates Method in Achilles Tendinopathy Rehabilitation
Achilles Tendinopathy (AT) is characterized by pain, swelling and dysfunction. Rehabilitation strategies focus on conservative treatment, with eccentric exercise being the main and most popular option.
- Conditions
- Achilles Tendinopathy, Eccentric Exercise, Pilates Method, Pilates Exercise
- Trial name
- NCT07039643
- Testing
- Pilates exercise, Alfredson protocol
- Where
- Greece
- Volunteers
- 49 people
- Sponsor
- University of West Attica
Tendon Tear, Tendinopathy
Eendoscopic Versus Open Flexor Hallucis Longus Transfer in Managing Various Tendon Achilles Disorders
A well-established protocol for the treatment or augmentation a wide range of Achilles disorders including chronic Achilles tendon (AT) rupture, Achilles insertional tendinopathy, Haglund syndrome and among others, is a Flexor…
- Conditions
- Tendon Tear, Tendinopathy, Achilles Tendon Ruptures, Achilles Injuries Tendon
- Trial name
- NCT06639308
- Testing
- Endoscopic Flexor Hallucis longus tendon transfer to tendon achilles, Open Flexor Hallucis longus transfer to tendon achilles
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Achilles Tendon Rupture, Ankle Fractures
Swedish Multicenter Trial of Outpatient Prevention of Leg Clots
Lower limb immobilization is associated with high risk of complications, i.e. venous thromboembolism (VTE) and failed healing. Pharmacoprophylaxis of VTE is in leg-immobilized patients, however, low- or non-effective and…
- Conditions
- Achilles Tendon Rupture, Ankle Fractures, Venous Thromboembolism
- Trial name
- StopLegClots (NCT03259204)
- Testing
- Adjuvant IPC
- Where
- Sweden
- Volunteers
- 1,400 people
- Sponsor
- Karolinska University Hospital
Achilles Tendon Rupture
Prospective Study on Artelon® Tissue Reinforcement in Repair of Chronic Ruptures and Re-ruptures of the Achilles Tendon
The aim of this study is to evaluate the surgical and clinical outcome of Artelon® Tissue Reinforcement in repair of chronic ruptures or re-ruptures of the Achilles tendon, with regard to lower leg and foot function, pain and…
- Trial name
- NCT01237613
- Testing
- Artelon
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Orthopedic Foot and Ankle Center, Ohio
Tendinopathy, Insertional Achilles Tendinopathy
Evaluation of Collagen-based Medical Device Treatment Combined With Physiotherapy in Subjects With Achilles Tendinopathy.
Achilles tendinopathy is a condition characterized by inflammation of the Achilles tendon. Achilles tendinopathies are classified into insertional tendinitis and noninsertional tendinitis.
- Conditions
- Tendinopathy, Insertional Achilles Tendinopathy, Achilles Tendinopathy, Peritendinitis
- Trial name
- AKITENMED (NCT05464498)
- Testing
- MD-Tissue Collagen Medical Device, eccentric strengthening protocol
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Guna S.p.a
Achilles Tendon Rupture, Achilles Tendon Surgery
Endoscopic Flexor Hallucis Longus Transfer vs Minimally Invasive Repair in Acute Achilles Tendon Rupture
The goal of this observational study is to compare the outcomes of two different surgical techniques (Endoscopic Flexor Hallucis Longus transfer - Group 1 vs Minimally Invasive primary repair - Group 2) for patients with acute…
- Conditions
- Achilles Tendon Rupture, Achilles Tendon Surgery, Achilles Tendon Injury
- Trial name
- NCT06114368
- Testing
- Surgery for the treatment of Acute Achilles tendon rupture
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki
Achilles Pain, Achilles Tendinosis
Achilles Tendinosis Study; Comparison of Radiofrequency to Surgical MicroDebridement
This is a research study to evaluate the outcomes after the study procedure for pain and discomfort in the heel caused from an injury in the Achilles tendon which is located on the back of the foot (commonly called "Achilles…
- Conditions
- Achilles Pain, Achilles Tendinosis, Heel Pain
- Trial name
- NCT00534781
- Testing
- plasma microdebrider, Mechanical Surgical Debridement
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ArthroCare Corporation
Ankle Sprains, Ankle Fractures
Accumulative Effects of Talus Mobilization
The purpose of this study is to verify the effect of anteroposterior talus mobilization on range of motion, pain, and functional capacity in participants with sub-acute and chronic ankle injuries.
- Conditions
- Ankle Sprains, Ankle Fractures, Ankle Dislocations, Ankle Bruises
- Trial name
- NCT02244008
- Testing
- joint mobilization, manual contact
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Federal University of Minas Gerais
Achilles Tendinitis, Tendinopathy
Clinical Trial to Evaluate the Adjuvant Effect of Shock Wave Therapy in the Insertional Achilles Tendinopathy
Background: There is no consensus regarding the treatment of insertional tendinopathies. The good results of the eccentric training in the management of the non-insertional Achilles tendinopathy were not reproducible in the…
- Trial name
- NCT02757664
- Testing
- Shock Wave Therapy, Eccentric Exercises
- Where
- Brazil
- Volunteers
- 119 people
- Sponsor
- Federal University of São Paulo