Clinical trials: Acceptability
Dry Eye Syndromes
Efficacy and Acceptability of Two Lubricant Eye Drops
Efficacy and acceptability of two new artificial tears following two weeks of treatment in patients with dry eye. Patients will be randomized to 1 of 2 treatments for 7 days then crossover to the alternate treatment for 7 days.
- Trial name
- NCT00756678
- Testing
- Lubricant Eye Drops (Optive™), Lubricating Eye Drops (blink® Tears)
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Allergan
Contraception
Efficacy and Safety of the Combined Oral Contraceptive (COC) NOMAC-E2 Compared to a COC Containing DRSP/EE (292001)(COMPLETED)(P05724)
The primary purpose of this study is to assess contraceptive efficacy, vaginal bleeding patterns (cycle control), general safety and acceptability of the nomegestrol acetate-estradiol (NOMAC-E2) combined oral contraceptive (COC)…
- Trial name
- NCT00511199
- Testing
- NOMAC-E2, DRSP-EE
- Volunteers
- 2,152 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Contraception
Safety and Acceptability Study of a Non-Hormonal Ring
This is a feasibility, multi-center, open-label, non-significant risk device study for a non-hormonal contraceptive ring.
- Trial name
- NCT03598088
- Testing
- Ovaprene
- Where
- 6 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Daré Bioscience, Inc.
Lung Cancer, Neoplasms, Lung
Remote Monitoring of Lung Cancer Patient-Reported Outcomes Using Moovcare®
The purpose of this study is to demonstrate how Moovcare®, a mobile medical application, can be used to monitor Patient-Reported Outcomes (PROs) related to cancer treatment, cancer complications, and cancer relapse in patients…
- Conditions
- Lung Cancer, Neoplasms, Lung, Neoplasms, Pulmonary, Pulmonary Cancer
- Trial name
- LC-PRO (NCT05011890)
- Testing
- Moovcare® use
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Myopia
A Multi-Center Investigation of Patient Acceptability of OPTI-FREE RepleniSH® Multi-Purpose Disinfecting Solution (MPDS)
The purpose of this study was to demonstrate that current successful fulltime daily wear soft contact lens wearers using competitive multi-purpose solutions will note improved comfort when using OPTI-FREE RepleniSH®.
- Trial name
- NCT00772707
- Testing
- Multi-Purpose Disinfecting Solution (OPTI-FREE RepleniSH), Contact Lenses
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Endometrial Cancer
Telehealth-Based Resistance Training Intervention for Endometrial Cancer Survivors
This 2-arm pilot trial will enroll 40 participants to test the feasibility, adherence, and benefits of a home-based strength training intervention for endometrial cancer survivors relative to a wait-listed control group.
- Trial name
- NCT03722030
- Testing
- Baseline Measures, Strength-Training, Mid-point Measures
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Wisconsin, Madison
Metabolic Syndrome
P20 Extending Sleep to Reverse Metabolic Syndrome
This pilot study will test the acceptability and feasibility of a sleep extension intervention in community-dwelling, short-sleeping, racially/ethnically diverse middle-aged adults with MetS.
- Trial name
- NCT03596983
- Testing
- Sleep Intervention, Week 2 Intervention
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- NYU Langone Health
HIV Infections
Improving Treatment and Retention Adherence in Nontraditional Settings
This is a hybrid implementation-effectiveness study using both qualitative and quantitative methods. The research aims to examine whether providing a new, but approved, HIV once a month injection treatment…
- Trial name
- I-TRAINS (NCT04973254)
- Testing
- CAB-RPV LA, Standard treatment within an HIV clinic
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Boston Medical Center
Heart Failure
Values-Affirmation Intervention Targeting Medication Adherence in Older Adults With Heart Failure
Heart failure (HF) represents a significant public health concern. Medication non-adherence represents a modifiable contributor to costly hospital readmissions in older adults with HF.
- Trial name
- NCT05310877
- Testing
- Values-Affirmation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- The Miriam Hospital
Delirium
Feasibility and Acceptability of Using Weighted Blankets to Prevent and /or Mitigate Delirium
The use of weighted blankets to avert or alleviate Delirium in Adult ICU patients.
- Trial name
- NCT06161480
- Testing
- Weighted Blanket
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Autism, Autism Spectrum Disorder
First CRUSH: Piloting the Preliminary Feasibility and Acceptability of the Competence in Romance and Understanding Sexual Health (CRUSH) Curriculum
The goal of this clinical trial is to learn about the feasibility and acceptability of a behavioral intervention in designed to provide sexual education and improve the behavioral skills of autistic adults for intimate…
- Trial name
- NCT05910658
- Testing
- Competence in Romance and Understanding Sexual Health (CRUSH)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Boston Children's Hospital
Overweight and Obesity, PreDiabetes
Continuous Glucose Monitors (CGM) for Type 2 Diabetes (T2D) Risk Evaluation
The purpose of this research study is to determine whether continuous glucose monitors (CGM) are a safe, effective, and acceptable way to evaluate type 2 diabetes risk in youth as compared to the standard 2-hour oral glucose…
- Conditions
- Overweight and Obesity, PreDiabetes, Insulin Resistance
- Trial name
- NCT05404711
- Testing
- CGM
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mary Ellen Vajravelu, MD
Acceptability of Semi-recumbent Pedal Desk
Workers' Acceptability of a Prototype Integrated and Interactive Pedal Desk
The purpose of this study is to assess full-time workers'impressions and acceptability of a prototype pedal desk. The pedal-desk is a semi-recumbent (upright) portable pedal mechanism that allows workers to complete tasks in a…
- Trial name
- WAPD (NCT01956071)
- Testing
- WAPD
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
HIV Infections
A Safety, Tolerability, Acceptability, and Pharmacokinetic (PK) Study of Cabotegravir (CAB) in Healthy Human Immunodeficiency Virus (HIV)-Uninfected Chinese Men
The pre-exposure prophylaxis (PrEP) is an important component in the overall strategy for prevention of HIV infection. Cabotegravir (CAB) is an integrase strand transfer inhibitor currently in development for treatment and…
- Trial name
- NCT03422172
- Testing
- Oral CAB, CAB LA
- Where
- 3 sites in China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Hepatitis C, Chronic
The No One Waits Study: Acceptability and Feasibility of Community-based Point-of-diagnosis HCV Treatment Study
Direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV) offers a cure to those with chronic HCV infection. For marginalized communities, linkage to care services often aren't enough to overcome barriers to accessing the…
- Trial name
- NOW (NCT03987503)
- Testing
- Epclusa (SOF/VEL), Standard of care, Fibroscan® 430 Mini Plus
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Influenza
Inactivated Influenza Vaccine Delivered by Microneedle Patch or by Hypodermic Needle
Title: A Phase I Study of The Safety, Reactogenicity, Acceptability and Immunogenicity of Inactivated Influenza Vaccine Delivered either by Microneedle Patch or by Hypodermic Needle.
- Trial name
- NCT02438423
- Testing
- Inactivated influenza vaccine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mark Prausnitz
HIV Infections
Acceptability, Safety, and Use of Daily Truvada Pre-Exposure Prophylaxis in Adolescents
Truvada (emtricitabine/tenofovir disoproxil fumarate, or FTC/TDF) is a type of antiretroviral (ARV) medicine that is commonly used to treat HIV.
- Trial name
- NCT02213328
- Testing
- Truvada
- Where
- 2 sites in South Africa
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HPV-Related Malignancy
Postpartum HPV Vaccination
Human papillomavirus (HPV)-related cancers are on the rise in the United States. Furthermore, greater than 90% of cervical cancer cases are attributable to HPV, and cervical cancer disproportionately affects women of color in…
- Trial name
- NCT03451071
- Testing
- Gardasil9
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- University of Alabama at Birmingham
Contraception, Malposition of Intrauterine Contraceptive Device
LNG-IUS at 2 Weeks Postpartum
This is a study of 50 postpartum women interested in having the Mirena® LNG-IUS placed for contraception. The Mirena® is an FDA approved intrauterine contraceptive device that provides contraception for 5 years with excellent…
- Trial name
- LNG-IUS (NCT02121067)
- Testing
- Levonorgestrel Intrauterine System (LNG-IUS)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Covid19, Coronavirus Infection
Mouth Rinses for Inactivation of COVID-19
Randomized, double-blind prospective trial to test the efficacy and acceptability of therapeutic, antiseptic mouth rinses to inactivate severe acute respiratory syndrome coronavirus (SARS-CoV-2) in saliva of COVID-19 positive…
- Conditions
- Covid19, Coronavirus Infection, SARS-CoV-2 Infection
- Trial name
- MOR (NCT04584684)
- Testing
- 0.9% w/v NaCL Saline, 1.5% w/v Hydrogen Peroxide, 0.12% Chlorohexidine Gluconate
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill