Clinical trials: Acceptability
Parkinson's Disease
The Effectiveness of Motor-motor and Motor-cognitive Dual-task Training Interventions on Balance in People With Parkinson's Disease: a Feasibility Study
This study aims to test the feasibility and acceptability of home-based motor-motor dual-task training and motor-cognitive dual-task training interventions, and balance-related outcome measures which may be used in an anticipated…
- Trial name
- NCT05710588
- Testing
- motor-motor dual-task training, motor-cognitive dual-task training
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Plymouth
Infant Formula Intolerance
Acceptability and GI Tolerance of an Alpha-lactalbumin-enriched Formula
A single center, non-controlled trial to document the gastrointestinal (GI) tolerability of the study formula (SF), containing a whey protein concentrate enriched with alpha-lactalbumin (WPC alpha-lac) fed for 6 weeks to healthy…
- Trial name
- NCT02431377
- Testing
- S-26 Gold
- Where
- Philippines
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Posttraumatic Stress Disorder
Effectiveness and Acceptability of Stellate Ganglion Block for Posttraumatic Stress Disorder Symptoms - Acceptability
This qualitative study will use focus groups, small group interviews, and individual interviews (both in person and over the phone) to compile a range of perspectives on service members' decision-making processes and information…
- Trial name
- NCT03302312
- Where
- 3 sites in United States, Germany
- Volunteers
- 54 people
- Sponsor
- RTI International
PTSD, Post Traumatic Stress Disorder
Feasibility of a Digital Therapeutic for Adults With Posttraumatic Stress Disorder (PTSD)
This study is exploring the efficacy of a digital therapeutic app in reducing symptoms of posttraumatic stress disorder (PTSD) in adults.
- Trial name
- NCT06868446
- Testing
- OTX-601 Digital Therapeutic - Version 1, OTX-601 Digital Therapeutic - Version 2, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oui Therapeutics, Inc.
Feasibility Studies, Physical Activity
AI-Based Personalized Exercise Prescription Through Mobile Health on Physical Activity and Health Outcomes in Older Adults: A Feasibility Study
The purpose of this research is to investigate the feasibility, acceptability, appropriateness, and preliminary efficacy of a wearable and artificial intelligence-driven mobile application-based exercise prescription grounded in…
- Conditions
- Feasibility Studies, Physical Activity, Mental Health (Depression), Anxiety
- Trial name
- NCT07768670
- Testing
- Fitness app powered by AI and wearable device
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
HIV Infections
Improving Treatment and Retention Adherence in Nontraditional Settings
This is a hybrid implementation-effectiveness study using both qualitative and quantitative methods. The research aims to examine whether providing a new, but approved, HIV once a month injection treatment…
- Trial name
- I-TRAINS (NCT04973254)
- Testing
- CAB-RPV LA, Standard treatment within an HIV clinic
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Boston Medical Center
Enteral Nutrition (Food for Special Medical Purposes), Enteral Feeds
A Single Arm Intervention Study to Assess the Acceptability, Tolerance and Ease of Use of Wilbo's Blends+ (Commercial Enteral Feed Based on Real Food) When Used as Part of a Dietitian Prescribed Enteral Feeding Plan
The goal of this observational study is to learn if tube-fed children and young people (age 3-15 years) find Wilbo's Blends+ (a new nutritionally complete enteral formula containing real food ingredients) acceptable, tolerable…
- Conditions
- Enteral Nutrition (Food for Special Medical Purposes), Enteral Feeds, Enteral Tube Nutrition, Gastrostomy Tube
- Trial name
- Wilbo's Blends (NCT07036081)
- Testing
- Wilbo's Blends+
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Fetal Surgery, Myelomeningocele
Fetal Surgery Interview Study: Parental Perceptions of Fetal Surgery
Open maternal-fetal surgery is currently used on fetuses with myelomeningocele (MMC). Fetoscopic or minimal access fetal surgery is also being used to treat fetuses with congenital diaphragmatic hernia (CDH).
- Conditions
- Fetal Surgery, Myelomeningocele, Congenital Diaphragmatic Hernia
- Trial name
- NCT03788122
- Testing
- In-depth interview
- Where
- 2 sites in Belgium, United Kingdom
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Prostate Cancer
Acceptability of Artificial Intelligence in the Diagnosis of Prostate Cancer
This study investigates the acceptability of artificial intelligence (AI) as a diagnostic support tool among patients with localized prostate cancer and healthcare providers, as well as their willingness to share health data for…
- Trial name
- AccAI (NCT07074405)
- Testing
- Questionnaire and Physical Exam
- Where
- Belgium
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Suicide and Self-harm, Suicide
Examining Feasibility, Acceptability, and Sustainability of a Novel Personalized Smartphone Intervention for Suicide - Randomized Trial
The primary aim of the present study is leverage existing infrastructure to develop novel technological features for a novel personalized smartphone intervention system, called the Mobile Application to Prevent Suicide (MAPS)…
- Conditions
- Suicide and Self-harm, Suicide, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT05202756
- Testing
- Mobile Application to Prevent Suicide (MAPS), EMA Monitoring Only
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Butler Hospital
Heart Failure
Values-Affirmation Intervention Targeting Medication Adherence in Older Adults With Heart Failure
Heart failure (HF) represents a significant public health concern. Medication non-adherence represents a modifiable contributor to costly hospital readmissions in older adults with HF.
- Trial name
- NCT05310877
- Testing
- Values-Affirmation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- The Miriam Hospital
Perinatal Anxiety, Perinatal Depression
Feasibility and Acceptability of a Novel Cognitive Behavioral Skills Mobile App for Pregnant and Postpartum Individuals
This study aims to assess the feasibility and acceptability of the Maya Perinatal Cognitive Behavioral Skills App, a novel app for pregnant and postpartum individuals experiencing difficulties with mood, anxiety, or stress.
- Trial name
- NCT05897619
- Testing
- Experimental: Maya Perinatal Cognitive Behavioral Skills App
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Weill Medical College of Cornell University
HPV Infection, HIV Infections
Feasibility of HPV Testing With Mail-delivered Sample Collection Kits
People living with human immunodeficiency virus (PLWH) have an estimated 1.6-6.0 times increased risk of developing oropharyngeal cancer (OPC) compared with individuals in the general population.
- Conditions
- HPV Infection, HIV Infections, HPV-Related Malignancy
- Trial name
- NCT07087145
- Testing
- Mail-based Saliva Sample Kit, Study-related Surveys
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- University of California, San Francisco
Mild Cognitive Impairment (MCI), Memory Disorders, Age Related
Music for the Mind Study
The goal of this pilot clinical trial is to learn if older adults with mild cognitive impairment (MCI) find two music programs equally acceptable.
- Conditions
- Mild Cognitive Impairment (MCI), Memory Disorders, Age Related, Memory Decline
- Trial name
- M4M (NCT06866327)
- Testing
- Piano lessons, Music Lessons
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Rochester
Migraine Headache
Effectiveness and Acceptability of MINDFULNESS by Smartphone, for Patients with Chronic Migraine and Medication Overuse
Chronic Migraine is a disabling condition that affects the 2% of migraine population. It is often associated with medication overuse that makes this condition very difficult to treat.
- Trial name
- ChroMig-Smart (NCT04389372)
- Testing
- Mindfulness
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Pediatric Cancer
TEMOkids Study : A Phase I Pediatric Study for KIMOZO, Oral Suspension of Temozolomide
Non-randomized, international, multi-centre, open-label, single arm study to determine the pharmacokinetic (PK) parameters of a single dose of an oral suspension of temozolomide (KIMOZO) in the pediatric population aged 1 year…
- Trial name
- NCT04610736
- Testing
- Temozolomide Oral Suspension
- Where
- 11 sites in France, Germany and 3 more
- Volunteers
- 49 people
- Sponsor
- Orphelia Pharma
Placenta Accreta
Evaluation of Clinical Outcomes and Acceptability of an Anatomical Classification for Placenta Accreta Spectrum
This study evaluates the clinical implementation of intra-operative topographic classification system for PAS. In addition to a standard of care risk stratification prenatal ultrasound for patients with a risk of PAS, this study…
- Trial name
- NCT07283042
- Testing
- Total Hysterectomy, Modified subtotal hysterectomy, One-Step Conservative Surgery
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Gestational Diabetes, Hyperglycemia
Early Investigation of Glucose Monitoring After Gestational Diabetes Pilot
One third of women with gestational diabetes (GDM), diabetes diagnosed during pregnancy, have abnormal glucose levels within 3 years after pregnancy, but follow up is low.
- Trial name
- ENGAGED (NCT06184373)
- Testing
- Continuous glucose monitor, Oral Glucose Tolerance Test, Hemoglobin A1c
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Gastrointestinal Diseases
A Phase IV Study, of the Efficacy, Safety, and Acceptability of Moviprep® Versus Colopeg® in Colonoscopy Preparation
Primary: To demonstrate the superiority of Moviprep® versus Colopeg® in gut cleansing prior to colonoscopy. Secondary: To assess the safety of Moviprep® versus Colopeg®. To assess acceptability of Moviprep® versus Colopeg®.
- Trial name
- NORMO (NCT00605228)
- Testing
- MOVIPREP, COLOPEG
- Where
- 21 sites in France
- Volunteers
- 400 people
- Sponsor
- Norgine
HIV Infections, HIV/AIDS
Acceptability and Feasibility of Unsupervised HIV Self-Testing Among Networks of Men
The purpose of this study is to recruit and train men to promote HIV self-testing to their network members in their camps and examine the efficacy of a peer-led HIV self-testing intervention on the uptake of HIV testing among men.
- Conditions
- HIV Infections, HIV/AIDS, Hiv
- Trial name
- STEP (NCT03891407)
- Testing
- Self-Testing Education and Promotion
- Where
- Tanzania
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of South Carolina