Clinical trials: Abuse Physical
Post-Traumatic Stress Disorder Complex, Psychiatric Disorder
Evaluation of the Efficacy of "Lifespan Integration" (LI) Therapy in Patients With Complex Post-Traumatic Stress Disorder
The study aims to evaluate the efficacy of a relatively new type of psychotherapy called Lifespan Integration (LI) in patients suffering of complex PTSD
- Conditions
- Post-Traumatic Stress Disorder Complex, Psychiatric Disorder, Abuse Neglect, Abuse Physical
- Trial name
- EVALI (NCT06535243)
- Testing
- Lifespan Integration Therapy (LI)
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Centre Hospitalier St Anne
Nitrous Oxide Abuse, Subacute Combined Cord Degeneration
Neurological Recovery Following NOS-SACD
Nitrous oxide has become an increasingly popular recreational drug amongst young people, particularly at festivals, nightclubs and parties.
- Conditions
- Nitrous Oxide Abuse, Subacute Combined Cord Degeneration, Neurologic Symptoms, Paresthesia
- Trial name
- NCT05714917
- Testing
- Observational study with no interventions
- Where
- 3 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Substance Abuse, HIV Infections
Healthy Activities for Prize Incentives
In this Stage 1 therapy development project, we plan to develop, formalize, and derive effect size estimates of a contingency management (CM) therapy that focuses on improving health, especially as related to increasing low…
- Trial name
- HAPI (NCT00717444)
- Testing
- contingency management
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- UConn Health
Methamphetamine Dependence, Methamphetamine Abuse
Varenicline as a Treatment for Methamphetamine Dependence
The primary purpose of the study is to determine the effects of treatment with varenicline (1 and 2 mg daily), compared to treatment with placebo, on methamphetamine-induced craving and subjective effects in…
- Conditions
- Methamphetamine Dependence, Methamphetamine Abuse, Substance Abuse
- Trial name
- Varenicline (NCT01571167)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Baylor College of Medicine
Domestic Violence, Physical Violence
Impact Assessment of the Rural Response System to Reduce Violence Against Women in Ghana
AIM: To assess the community level impact of the Gender Centre's Rural Response System (RRS) in reducing violence against women (VAW) in Ghana.
- Conditions
- Domestic Violence, Physical Violence, Sexual Violence
- Trial name
- GhanaCHiPS (NCT03237585)
- Testing
- Rural response system (RRS) intervention to reduce violence against women
- Where
- Ghana
- Volunteers
- 3,280 people, healthy volunteers welcome
- Sponsor
- Medical Research Council, South Africa
Cannabis Use, Cannabis
Investigating Real-world Stress-related Mechanisms in Heavy Cannabis Users
This research project proposes a novel approach to elucidate the biological adaptations associated with heavy cannabis use and to assess whether such adaptations are predictive of higher cannabis craving in response to both…
- Conditions
- Cannabis Use, Cannabis, Cannabis Abuse
- Trial name
- CLR2 (NCT05833230)
- Testing
- Intensive Day Monitoring
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Yale University
Narcotic Abuse, Opioid-related Disorders
Abuse Potential Assessment of Intranasally Administered EMBEDA Compared To Morphine Sulfate Controlled Release And Placebo
This was a single-dose, randomized, double-blind, placebo-controlled, 3 way crossover study designed to evaluate the relative abuse potential of crushed EMBEDA® compared to morphine sulfate CR tablets and placebo in healthy male…
- Conditions
- Narcotic Abuse, Opioid-related Disorders, Analgesia, Chronic Pain
- Trial name
- NCT01595867
- Testing
- EMBEDA - morphine sulfate/ naltrexone hydrochloride, morphine sulfate CR crushed.
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Pfizer
Cannabis, Ketamine
THC and Ketamine Effects in Humans: Relation to Neural Oscillations and Psychosis
The aim of the research protocol is to evaluate cannabinoid-glutamate interactions in humans. As part of this aim the investigators will assess the safety and tolerability of the combination of NMDA antagonist, ketamine, and the…
- Trial name
- NCT04199468
- Testing
- Active Delta-9-THC, Active Ketamine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yale University
Diet, Physical Activity
Improving Health Behaviors Through Telephone Linked Care
The investigators propose to conduct a randomized controlled trial at the patient level of the Telephone Linked Care - Behavioral Change (TLC-BC) system, which is designed to promote smoking cessation, reduce risky drinking, and…
- Conditions
- Diet, Physical Activity, Smoking, Alcohol Abuse
- Trial name
- NCT00314197
- Testing
- Telephone Linked Care - Behavior Change Counseling System, Telephone-linked behavioral counseling
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- American Academy of Family Physicians
Stigma, Activity Space
Health Outcomes by Neighborhood - Baltimore
Background: Researchers have been studying patterns of mood and drug use in specific neighborhoods. This study will look at environmental factors that may affect drug use, addiction, and treatment seeking in Baltimore…
- Conditions
- Stigma, Activity Space, Social Networks, HIV Status
- Trial name
- NCT01571752
- Where
- United States
- Volunteers
- 1,651 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Depression, Anxiety
Self-Defense Training in Women With Trauma
Previous research has shown that self-defense training can lead to gains in women's assertiveness, self-esteem, self-efficacy, and physical competence, and decreases in anxiety, helplessness, fear, and avoidant behaviors.
- Conditions
- Depression, Anxiety, Stress Disorders, Post-Traumatic
- Trial name
- NCT01380379
- Testing
- Life skills and self-defense training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Stanford University
Substance-Related Disorders, Drug Abuse
Structured Physical Exercise in Short-term Inpatient Treatment of Substance Use Disorder
In 2017, structured physical exercise with high intensity was implemented as a part of the treatment program at St. Olav Hospital Clinic of Substance Use and Addiction Medicine.
- Conditions
- Substance-Related Disorders, Drug Abuse, Drug Dependence
- Trial name
- NCT04141202
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- St. Olavs Hospital
Posttraumatic Stress Disorder
Client-directed Cognitive Processing Therapy
This study will take place over approximately 6 months and includes 3 assessment appointments (where information will be gathered, but no direct treatment provided) and 12 treatment sessions of cognitive processing therapy if…
- Trial name
- CPT (NCT02684994)
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Indianapolis
Opioid-related Disorders, Opioid Addiction
ER/LA Opioid Surveillance for Emergency Department Visits and Hospitalizations for Overdose and Poisoning
Study to evaluate the impact of the ER/LA opioid REMS program on the incidence of Emergency Department visits and hospitalizations for overdose/poisoning and death among patients prescribed ER/LA opioid analgesics.
- Conditions
- Opioid-related Disorders, Opioid Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- NCT02866266
- Testing
- Retrospective database review
- Volunteers
- 183,452 people
- Sponsor
- ER/LA Opioid REMS Program Companies (RPC)
Violence by Teachers
School-based Prevention of Teacher Violence Against Children in Zambia
The United Nations Conventions on the Rights of the Child UN General Assembly, 1989), outlawed violence against children worldwide.
- Trial name
- ICC-T Zambia (NCT07773961)
- Testing
- Interaction Competencies with Children
- Where
- Zambia
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Tobias Hecker, PhD
Cannabis Dependence
Interactions Between Physical Activity and Cannabis Use in Adults
In this study the investigators will explore the relationship between physical activity and cannabis use. The investigators will compare regional brain activation detected by imaging technique(fRMI) before and after exercise in…
- Trial name
- NCT00838448
- Testing
- Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Alcohol Use Disorder, Alcohol Drinking
Virtual Incentive Treatment for Alcohol
The overall objective of this program of research is to utilize phosphatidylethanol (PEth), a blood-based biomarker that can detect alcohol use for up to 28 days to deliver a feasible telehealth-based 26-week CM intervention.
- Conditions
- Alcohol Use Disorder, Alcohol Drinking, Alcohol Abuse, Alcohol Dependence
- Trial name
- VITA (NCT06265506)
- Testing
- Contingency Management, Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Washington State University
Unsafe Sex, Physical Violence
HIV/STI Risk Reduction for Incarcerated Women With Interpersonal Violence
The pilot study aims to conduct a randomized pilot trial in a sample of 40 incarcerated women with lifetime interpersonal violence who are 6-10 weeks away from release to demonstrate the feasibility and acceptability of the…
- Conditions
- Unsafe Sex, Physical Violence, Sexual Assault, Sexual Abuse
- Trial name
- NCT01907126
- Testing
- Nutrition Program (NP), Women's Prison CoOp (WPC)
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Brown University
Fatigue, Older People--Abuse of
The Associated Factors With Fatigue in Older Adults Living in a Rest Home
Fatigue is an important and prevalent problem in older adults. The ratio of fatigue may rise in older adults who live in nursing homes/rest homes.
- Trial name
- NCT04247789
- Testing
- Self-reported questionairres
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Ordu University
Alcohol Drinking, Alcohol Abuse
Novel Real-world Methods in Social Drinkers and AUD
This research project proposes a novel approach to elucidate the biological adaptations associated with Alcohol Use Disorder and to assess whether such adaptations are predictive of higher alcohol craving in response to both…
- Conditions
- Alcohol Drinking, Alcohol Abuse, Alcohol Use Disorder
- Trial name
- ALR (NCT05155176)
- Testing
- Intensive Day Monitoring
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Yale University