Clinical trials: Abscess
Tubo-ovarian Abscess
Management of Tubo-ovarian Abscess: a Single Center Experience
Electronic database of our tertiary obstetrics and gynecology clinic was searched for patients who were treated for tub-ovarian abscess during the last 10 years (January 2010- November 2020).
- Trial name
- NCT04817631
- Testing
- tuboovarian abscess
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Toxoplasmosis, Cerebral, HIV Infections
A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDS
To evaluate the effectiveness and toxicity of oral azithromycin and pyrimethamine as acute therapy for toxoplasmic encephalitis in AIDS patients.
- Trial name
- NCT00000966
- Testing
- Azithromycin, Pyrimethamine, Leucovorin calcium
- Where
- 11 sites in United States
- Volunteers
- 45 people
- Sponsor
- Pfizer
Liver Abscess, Pyogenic
Pyogenic Liver Abcess in Guadeloupe
Liver abscesses are infections of the liver parenchyma, most often bacterial, occurring via the biliary tract, bloodstream, or by direct spread. Although rare, they are serious, with a mortality rate of around 15%.
- Trial name
- PYG (NCT07579104)
- Where
- Guadeloupe
- Volunteers
- 58 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Abscess
Management of Skin and Soft Tissue Abscesses in Pediatric Patients After Incision and Drainage
The purpose of the study is to compare rates of cure of abscesses with and without antibiotic treatment after incision and drainage.
- Trial name
- NCT00691600
- Testing
- oral trimethoprim/sulfamethoxazole
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Baylor College of Medicine
Fractures, Dislocations
Ketamine Versus Fentanyl as an Adjunct to Propofol-Assisted Emergency Department Procedural Sedation
We, the investigators at Queen's University, propose to conduct a randomized, double-blind, feasibility trial comparing low-dose ketamine versus fentanyl as adjuncts to Emergency Department procedural sedation with propofol.
- Conditions
- Fractures, Dislocations, Abscess, Anesthesia
- Trial name
- NCT00137085
- Testing
- ketamine
- Where
- Canada
- Volunteers
- 124 people
- Sponsor
- Queen's University
Acute Appendicitis, Acute Appendicitis Without Peritonitis
The Role of Preoperative HALP Score in Differentiating Complicated Acute Appendicitis
Acute abdomen is a frequently encountered clinical condition that can be fatal if not diagnosed early. Acute appendicitis is one of the causes of acute abdomen and is the most common clinical condition leading to acute abdomen…
- Conditions
- Acute Appendicitis, Acute Appendicitis Without Peritonitis, Acute Appendicitis With Appendix Abscess, Acute Appendicitis With Rupture
- Trial name
- Appendicitis (NCT07002671)
- Testing
- Appendectomy, blood sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 411 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Spinal Epidural Abscess
Prospective Analysis of Spinal Epidural Abscess
This is a prospective study involving all patients treated at the University of Kentucky for spinal epidural abscess over a 2-year period.
- Trial name
- SEA (NCT05464251)
- Testing
- Prospective chart review of subjects diagnosed with spinal epidural abscess
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Francis Farhadi
Hidradenitis Suppurativa, Acne Inversa
Evaluation of Safety and Efficacy of Avacopan in Subjects With Moderate to Severe Hidradenitis Suppurativa (AURORA)
Phase 2 study of Avacopan in Subjects with Moderate to Severe Hidradenitis Suppurativa
- Trial name
- NCT03852472
- Testing
- Avacopan
- Where
- 91 sites in United States
- Volunteers
- 435 people
- Sponsor
- Amgen
Hidradenitis Suppurativa
Open-label Study of the Safety and Efficacy of Adalimumab in the Treatment of Hidradenitis Suppurativa
The purpose of this study to evaluate the long term safety, tolerability and efficacy of adalimumab in subjects with moderate to severe hidradenitis suppurativa (HS).
- Trial name
- PIONEER (OLE) (NCT01635764)
- Testing
- adalimumab
- Volunteers
- 508 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Emergency Department Procedural Sedation, Fracture Reduction
Ketofol vs Propofol for Emergency Department Procedural Sedation and Analgesia
When patients come to the Emergency Department with injuries and infections they often need to have painful procedures performed that are essential to allowing them to recover.
- Conditions
- Emergency Department Procedural Sedation, Fracture Reduction, Abscess Incision and Drainage, Electrical Cardioversion
- Trial name
- NCT01211158
- Testing
- Ketofol, Propofol alone
- Where
- Canada
- Volunteers
- 284 people
- Sponsor
- Lions Gate Hospital
Cholecystitis, Acute, Elderly Infection
Percutaneous Transhepatic Cholangiography (PTHC) in Acute Cholecystitis and Clinical Outcomes
In a setting of acute cholecystitis (AC) one of the treatment option is percutaneous transhepatic cholangiography (PTHC) drainage.
- Conditions
- Cholecystitis, Acute, Elderly Infection, Drain Abscess
- Trial name
- NCT03087747
- Testing
- Percutaneous cholecystostomy
- Where
- Croatia
- Sponsor
- University of Split, School of Medicine
Anal Fistula
Do Antibiotics Prevent Anal Fistulae Formation?
Purpose: This randomized study assesses the effects of antibiotics on the formation of fistulae after drainage of anorectal abscesses.
- Trial name
- NCT01012843
- Testing
- Amoxicillin-Clavulanate
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 151 people
- Sponsor
- Ankara University
Brain Abscess
Circulating Cell-Free DNA for Brain Abscess Diagnosis: A Pilot Study
Brain abscess is a severe intracranial infection associated with significant morbidity and mortality. Standard management combines neurosurgical intervention, when feasible, with prolonged intravenous antibiotic therapy.
- Trial name
- METABCES-PoC (NCT07479225)
- Testing
- Plasma Microbial Cell-Free DNA Metagenomic Sequencing
- Where
- 2 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Liver Abscess, Amoebic Liver Abscess
Efficacy of Diloxanide Furoate as Additional Luminal Agent Along With Metronidazole for the Treatment of Amoebic Liver Abscess
Liver abscess is a common cause of presentation to medical emergency. Among the various causes of liver abscess, Amoebic liver abscess (ALA) is a frequent cause that can resemble pyogenic infections in tropical regions.
- Trial name
- DFALA RCT (NCT07807150)
- Testing
- Diloxanide furoate
- Where
- India
- Volunteers
- 220 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Anal Fistulas
Aspiration Treatment of Perianal Abscess
The purpose of this study is to compare aspiration and oral antibiotics with surgical incision in the treatment of perianal abscesses in terms of recurrence and subsequent fistula formation.
- Trial name
- NCT02585141
- Testing
- MEDIPLAST® (aspiration), incision, Clindamycin
- Where
- Denmark
- Volunteers
- 111 people
- Sponsor
- University of Southern Denmark
Perianal Abscess, Anal Fistula
Antibiotics After Incision and Drainage to Prevent Fistula Formation After First Episode of Perianal Abscess
The goal of this clinical trial is to learn if antibiotics can prevent the formation of fistula-in-ano after incision and drainage of a first time of perianal abscess in adults.
- Trial name
- RAPID (NCT07704359)
- Testing
- Amoxicillin + Clavulanate, Ciprofloxacin + Metronidazole
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- University of Illinois at Chicago
Pilonidal Cyst and Sinus Without Abscess
Karydakis Versus Limberg Flap for the Management of Primary Sacrococcygeal Pilonidal Sinus
study comparing the Karydakis and Limberg flaps
- Trial name
- NCT07271537
- Testing
- karydakis surgery, Limberg flap
- Where
- Egypt
- Volunteers
- 352 people
- Sponsor
- Zagazig University
Lacerations, Abscess
Effectiveness of Nitrous Oxide in the ED
This will be a randomized control trial. All patients for whom an emergency provider determines that abscess drainage or laceration repair are necessary will be considered for enrollment.
- Trial name
- NCT02703233
- Testing
- Nitrous Oxide, Oxygen
- Volunteers
- healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Peritonsillar Abscess
Assessing the Necessity of Prescribing Antibiotics (Clavulin or Clindamycin Versus Placebo) Post-peritonsillar Abscess Drainage
This study aims to look at the necessity for prescribing antibiotics post-drainage of peritonsillar abscesses (PTA). This will be a single-blinded randomized-control trial with two arms - patients receiving placebo versus those…
- Trial name
- PTA (NCT01715610)
- Testing
- Clavulin, Clindamycin
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Skin Disease, Bacterial, Abscess
Evaluation of 3 Versus 10 Days of Antibiotics in Skin Abscesses After Surgical Drainage
The objective of this study is to determine if there is a difference in treatment failures and recurrent skin infections when patients are given 3 or 10 days of antibiotics for uncomplicated skin abscesses after they have been…
- Trial name
- NCT02024867
- Testing
- Trimethoprim-Sulfamethoxazole
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Lucy Holmes, MD