Clinical trials: Abscess
Autoimmune Hepatitis, Primary Sclerosing Cholangitis
Liver-gut Axis Study Through Identification of Liver Disease-specific Microbiome
In this study, we aim to identify gut microbiomes specific to patients with chronic refractory liver disease and to conduct a gut-liver axis study on the pathogenesis and disease progression.
- Conditions
- Autoimmune Hepatitis, Primary Sclerosing Cholangitis, Non-Alcoholic Fatty Liver Disease, Liver Abscess
- Trial name
- LGAS (NCT06519162)
- Where
- South Korea
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chungnam National University Hospital
Brain Abscess
Circulating Cell-Free DNA for Brain Abscess Diagnosis: A Pilot Study
Brain abscess is a severe intracranial infection associated with significant morbidity and mortality. Standard management combines neurosurgical intervention, when feasible, with prolonged intravenous antibiotic therapy.
- Trial name
- METABCES-PoC (NCT07479225)
- Testing
- Plasma Microbial Cell-Free DNA Metagenomic Sequencing
- Where
- 2 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Hidradenitis Suppurativa
Hidradenitis - an Analysis of Genetic Traits and Linkages in Families
The aim of this study is to find a genetic link or family trait connecting persons with Hidradenitis Suppurativa (HS) to each other. As a result, discover the cause and perhaps treatment for Hidradenitis Suppurativa (HS).
- Trial name
- NCT05710393
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- University of Chicago
Cholecystitis, Acute Cholecystitis
Fundus-first Laparoscopic Cholecystectomy
Bile duct injury (BDI) remains the most feared complication of laparoscopic cholecystectomy, particularly in difficult gallbladder cases.
- Conditions
- Cholecystitis, Acute Cholecystitis, Pericholecystic Abscess
- Trial name
- FFLC (NCT07137546)
- Testing
- Fundus-First Laparoscopic Cholecystectomy ( FFLC), Classical Laparoscopic Cholecystectomy (CLC)
- Where
- Egypt
- Volunteers
- 174 people
- Sponsor
- Minia University
Spinal Epidural Abscess
Prospective Analysis of Spinal Epidural Abscess
This is a prospective study involving all patients treated at the University of Kentucky for spinal epidural abscess over a 2-year period.
- Trial name
- SEA (NCT05464251)
- Testing
- Prospective chart review of subjects diagnosed with spinal epidural abscess
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Francis Farhadi
Pilonidal Cyst and Sinus Without Abscess, Pilonidal Sinus Disease
The Effect of Local Anesthesia Techniques on Postoperative Pain After Laser Treatment of Pilonidal Sinus
"Assessment of postoperative pain with conventional and tumescent local anesthesia in the laser treatment of pilonidal sinus." The aim of this study is to: examine the possible difference in postoperative pain between two local…
- Conditions
- Pilonidal Cyst and Sinus Without Abscess, Pilonidal Sinus Disease, Pilonidal Sinus Treatment, Laser Ablation
- Trial name
- NCT07408414
- Testing
- local anesthesia using 2% lidocaine, SiLaC, Questionnaire and physical examination
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Opća županijska bolnica Požega
Abscess
Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses
The objective of this Phase 2 study is to evaluate the efficacy of methylene blue photodynamic therapy (MB-PDT) performed at the time of percutaneous abscess drainage for disinfection of deep tissue abscesses.
- Trial name
- NCT06052956
- Testing
- Methylene Blue, Lipid Emulsion, Insertion of optical fiber
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Rochester
Lung Adenocarcinoma, Lung Abscess
Evaluation of Different Sizes of Left-Sided Double-Lumen Tubes for Thoracic Surgery in a Tertiary Level Teaching Hospital
Double lumen tubes (DLT) have become standard of care for one lung ventilation in thoracic and esophageal surgeries. Selection of accurate size of DLT is important to achieve proper one lung ventilation, prevent trauma to airway…
- Trial name
- NCT07373171
- Testing
- Intubation of patients undergoing thoracic surgery with left sided double lumen tube
- Where
- Nepal
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University, Nepal
Clinical Application of Dynamic Multimodal Analgesia Regimen After Perianal Abscess Surgery
Clinical Application of Dynamic Multimodal Analgesia Regimen After Perianal Abscess Surgery
This study aims to investigate whether the full-course multimodal analgesia regimen based on dynamic assessment (including the integrated traditional Chinese and Western medicine mode) can alleviate postoperative pain, reduce…
- Trial name
- NCT07358065
- Testing
- the traditional analgesic mode, Western Medicine Multimodal Analgesia, Integrated Traditional Chinese and Western Medicine Multimodal Analgesia
- Where
- China
- Volunteers
- 135 people
- Sponsor
- The Affiliated Hospital of Putian University
Perianal Abscess, Perianal Fistula
Perianal Abscess Recurrence and Fistula Formation: Antibiotics Following Incision and Drainage Trial
Most perianal abscesses (PA) result from an infection originating in anal crypts that extend into anal glands in the intersphincteric plane.
- Trial name
- PARFAIT (NCT04549311)
- Testing
- Antibiotic 1 arm (amoxicillin + clavulanic acid), Antibiotic 2 arm (ciprofloxacin + metronidazole)
- Where
- 3 sites in Canada
- Volunteers
- 15 people
- Sponsor
- Sunnybrook Health Sciences Centre
Uncomplicated Tubo Ovarian Abscess
Efficacy of Transvaginal Ultrasound-guided Aspiration for Treatment of Tubo-ovarian Abscess Compared With Laparoscopy
"Tubo-ovarian abscess (TOA) include pyosalpinx, ovarian abscess, tubo-ovarian abscess and Douglas abscess. The only randomized study evaluating TOA treatment reported a higher cure rate (90 versus 65%) when antibiotic therapy is…
- Trial name
- PACTOL (NCT03819309)
- Testing
- Ultrasound-guided transvaginal drainage, Laparoscopy
- Where
- France
- Volunteers
- 208 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Liver Abscess, Pyogenic
Laparoscopic Approach to Pyogenic Liver Abscess
Assess the efficacy and safety of laparoscopic management of liver abscess in achieving complete drainage and clinical recovery compared to conventional open or percutaneous methods, and to: 1.
- Trial name
- NCT07303829
- Testing
- Laproscopic
- Volunteers
- 30 people
- Sponsor
- Assiut University
Pneumonia, Pleural Effusion
Evaluation of Ultra-portable Ultrasound in General Practice
This is an interventional multi-centre study comparing two groups of general practitioners with or without an ultrasound scanner over a period of 6 months.
- Conditions
- Pneumonia, Pleural Effusion, Renal Colic, Hepatic Colic or Cholecystitis
- Trial name
- EPEMedG (NCT04127149)
- Testing
- Ultrasound scan
- Where
- France
- Volunteers
- 166 people
- Sponsor
- Hospices Civils de Lyon
Perforated Appendicitis
APPI-Cost Trial for Perforated Appendicitis
The purpose of this study to assess the clinical effectiveness and cost-effectiveness of povidone-iodine (PVI) irrigation in perforated appendicitis, to investigate barriers and facilitators to future implementation of PVI…
- Trial name
- NCT06705842
- Testing
- PVI, Usual Care
- Where
- United States
- Volunteers
- 346 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pilonidal Sinus Disorder, Pilonidal Cyst Without Abscess
SiLaC Laser Technique for Pilonidal Sinus - La Paz Cohort Study.
Pilonidal sinus disease (PSD) is a chronic inflammatory condition of the sacrococcygeal region that frequently affects young adults, often causing pain, drainage, and recurrent infection.
- Conditions
- Pilonidal Sinus Disorder, Pilonidal Cyst Without Abscess, Pilonidal Sinus, Pilonidal Cysts
- Trial name
- SiLaC-LaPaz (NCT07260643)
- Testing
- SilaC
- Volunteers
- 40 people
- Sponsor
- Hospital Universitario La Paz
Pilonidal Cyst and Sinus Without Abscess
Karydakis Versus Limberg Flap for the Management of Primary Sacrococcygeal Pilonidal Sinus
study comparing the Karydakis and Limberg flaps
- Trial name
- NCT07271537
- Testing
- karydakis surgery, Limberg flap
- Where
- Egypt
- Volunteers
- 352 people
- Sponsor
- Zagazig University
Intracranial Hemorrhage, Ventriculitis
Clearance of Intracranial Blood Products by Continuous Irrigation With the IRRAflow System
The study is a multi-center prospective cohort, controlled, phase 4 post-market registry evaluating the efficacy and radiographic outcomes associated with the use of the IRRAflow® Active Fluid Exchange System compared to standard…
- Conditions
- Intracranial Hemorrhage, Ventriculitis, Intracranial Abscess
- Trial name
- CRYSTAL (NCT06649097)
- Testing
- IRRAflow® CNS (Active Fluid Exchange) System
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Christopher P Kellner
Pain, Procedural, Minor Laceration
Ketamine as a Supplement to Local Anesthesia for Minor Procedures
This trial is a double-blind randomized controlled clinical trial of adults and children (ages 7 to less than 70 years). Patients who present to the ED and who undergo minor bedside procedures that require local anesthesia will…
- Conditions
- Pain, Procedural, Minor Laceration, Abscess
- Trial name
- INK-MP (NCT06284473)
- Testing
- Ketamine, Saline
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Loyola University
Chronic Apical Periodontitis, Necrosis of Pulp
Using Platelet-rich Fibrin in Regenerative Endodontic Treatment in Mature Permanent Teeth
This study aims to evaluate the antibacterial effects of injectable platelet-rich fibrin (i-PRF) in vitro, and to assess the clinical and radiographic outcomes of using advanced platelet-rich fibrin (A-PRF+) and i-PRF in…
- Conditions
- Chronic Apical Periodontitis, Necrosis of Pulp, Acute Apical Periodontitis of Pulpal Origin, Periapical Abscess
- Trial name
- NCT07192289
- Testing
- Using advanced platelet-rich fibrin (A-PRF+) or injectable platelet-rich fibrin (i-PRF) in regenerative endodontic treatment in mature permanent teeth.
- Where
- Vietnam
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Neck Abscess
Microbiological Study in Neck Space Infections: A Clinical and Microbiological Correlation
Analyze the microbiological spectrum of neck space infections and correlate it with clinical outcomes, with the goal of improving diagnostic and therapeutic approaches to these potentially serious infections \& to assess the…
- Trial name
- NCT07184515
- Volunteers
- 50 people
- Sponsor
- Assiut University