Clinical trials: Abortion in First Trimester
Abortion in First Trimester, Pain
Transcutaneous Electrical Nerve Stimulation for Pain Control During First-trimester Abortion
First-trimester abortion aspiration procedures are painful and sedation is typically provided. It is unsafe to drive after sedation due to the prolonged motor delay from some anesthetic agents.
- Trial name
- TENS 2 0 (NCT05320432)
- Testing
- Transcutaneous electrical nerve stimulation (TENS)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Stanford University
Abortion in First Trimester
Pharmacist Provision of Medication Abortion
This will be a pilot study among two pharmacists providing start to finish medication abortions to 10 patients utilizing a previously created toolkit.
- Trial name
- NCT04956731
- Testing
- Pharmacist Provision of Medication Abortion
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Abortion, Spontaneous, Abortion in First Trimester
Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage.o
The investigators are conducting a study on pain control for dilation and curettage (D\&C). Participants are eligible to enroll if they are a planning to have a D\&C in a participating clinic.
- Conditions
- Abortion, Spontaneous, Abortion in First Trimester, Pain Uterus, Abortion Early
- Trial name
- NCT03636451
- Testing
- 40cc buffered 0.5% lidocaine with 2 units of vasopressin paracervical block, 20cc 1% lidocaine with 2 units of vasopressin paracervical block
- Where
- 2 sites in United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Abortion in First Trimester, Pain, Procedural
Ketamine Versus Fentanyl for Surgical Abortions
Ketamine is commonly used for procedural sedation and analgesia. It is widely used for trauma cases in the emergency department and is considered a superior agent in the outpatient setting due to its lack of respiratory and…
- Conditions
- Abortion in First Trimester, Pain, Procedural, Opioid Use
- Trial name
- NCT04871425
- Testing
- Ketamine, Fentanyl
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Washington
First Trimester Abortion
A Randomized Controlled Trial of Three Antibiotic Regimens for First Trimester Abortions
This study, a double blinded randomized controlled trial, is being done to compare side effects of commonly used antibiotic regimens prior to same day abortion procedures.
- Trial name
- NCT02756403
- Testing
- Azithromycin, Doxycycline, Metronidazole
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Miscarriage in First Trimester
Misoprostol 400 µg Versus 200 µg for Cervical Ripening in 1st Trimester Miscarriage
Local current protocol for cervical ripening in 1st trimester miscarriage recommends 400 µg of misoprostol intravaginally 3 hours before uterine evacuation. This regime has been recommended by some international guidelines .
- Trial name
- MISO200 (NCT02957305)
- Testing
- Misoprostol 400mcg Tab, Misoprostol 200mcg Tab
- Where
- Brazil
- Volunteers
- 211 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Abortion in First Trimester
Auriculotherapy - Pain Management of Aspiration Abortion
Primary Objective: To assess whether usual care plus auricular acupressure with beads reduces subject-reported maximum pain during first trimester vacuum aspiration compared to usual care plus placebo.
- Trial name
- NCT03896022
- Testing
- Acupressure with Beads, Acupuncture with Needles
- Where
- United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Columbia University
Abortion in First Trimester
Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During First Trimester Abortion
High-frequency, high-intensity transcutaneous electrical nerve-stimulation (TENS) is an inexpensive and non-invasive pain control approach.
- Trial name
- NCT03187002
- Testing
- Transcutaneous electrical nerve stimulation (TENS), Moderate IV Sedation
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Stanford University
Abortion in First Trimester
Dextromethorphan as a Novel Non-opioid Adjunctive Agent for Pain Control in Medication Abortion
This study evaluates dextromethorphan as a non-opioid adjunctive medication for pain control during medication abortion. This is double-blinded, four-arm randomized controlled trial enrolling 156 women over a period of 9-12…
- Trial name
- DexMab (NCT03480009)
- Testing
- Dextromethorphan Hydrobromide, Avicel PH101 (Microcrystalline Cellulose NF) for Compounding, Oxycodone
- Where
- 2 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Study Investigator-Sponsor
First Trimester Abortion, Virtual Reality
Virtual Reality Experience in First Trimester D&C
Virtual reality (VR) has been used in health care settings to decrease anxiety and pain. This project is a feasibility study to evaluate whether virtual reality can be used in the setting of a first trimester pregnancy…
- Trial name
- NCT03533036
- Testing
- applied VR headset
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Spontaneous Abortion in First Trimester
Comparing Buccal and Vaginal Misoprostol in Management of Early Pregnancy Loss
First trimester miscarriages are common. When the failed pregnancy does not pass spontaneously on its own, it is called a missed abortion.
- Trial name
- NCT02141555
- Testing
- Vaginal Misoprostol, Buccal Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Abortion in First Trimester
Nitrous Oxide for Pain Management of First Trimester Surgical Abortion
The purpose of this research is to study the effect of nitrous oxide on pain felt by women having a surgical termination at less than 11 weeks compared to pain felt by women receiving oral pain medications.
- Trial name
- NAB (NCT02096575)
- Testing
- Nitrous oxide administration
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of New Mexico