Clinical trials: Abortion in First Trimester
Abortion in First Trimester
Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management With Medication Abortion Through 70 Days' Gestation
This is a double-blinded, randomized, placebo-controlled trial evaluating the use of High-frequency Transcutaneous Electrical Nerve Stimulation (HfTENS) compared to sham TENS for pain control during medication abortion with…
- Trial name
- NCT03925129
- Testing
- high frequency TENS treatment
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of Greater New York
Voluntary Termination of Pregnancy
Preoperative Ultrasound Evaluation of Gastric Contents in Voluntary Termination of Pregnancy During the First Trimester
This is an observational, prospective, monocentric, diagnostic study aiming to evaluate the diagnostic properties of the presence of nausea-vomiting in predicting the existence of gastric contents in preoperative surgical…
- Trial name
- ECHONAV (NCT06210308)
- Testing
- Data collection from gastric ultrasound
- Where
- France
- Volunteers
- 304 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Preeclampsia, Pregnancy Loss
Early Pregnancy Antioxidant Supplementation in the Prevention of Preeclampsia
Use of Juice Plus+ food supplements, when initiated in the first trimester and used continuously thereafter, will result in a lower incidence of preeclampsia and pregnancy complications.
- Trial name
- NCT00583635
- Where
- United States
- Volunteers
- 684 people
- Sponsor
- University of Mississippi Medical Center
Silent Miscarriage
Letrozole Versus Mifepristone and Misoprostol in Silent Miscarriage
Management of first trimester silent miscarriage can be by expectant, medical or surgical management. Surgical management by suction evacuation is associated with surgical risks (including risks to the womb that can affect…
- Trial name
- NCT06733727
- Testing
- Letrozole, Mifepristone
- Volunteers
- 884 people
- Sponsor
- The University of Hong Kong
Threatened Abortion in First Trimester
Progesterone in Threatened Abortion
The main objective of this study will be to assess the efficacy of natural progesterone at a daily dose of 25 mg/bid in the maintenance of early pregnancy in women with symptoms of threatened abortion.
- Trial name
- NCT02950935
- Testing
- Progesterone
- Where
- 4 sites in Italy
- Volunteers
- 4 people
- Sponsor
- IBSA Institut Biochimique SA
Abortion Early, Abortion in First Trimester
Using Telemedicine to Improve Early Medical Abortion at Home
The investigators plan a trial comparing telephone consultations for women requesting early medical abortion (EMA - under 10 weeks pregnant) to regular face-to-face consultations.
- Trial name
- UTAH (NCT04139382)
- Testing
- Telephone Consultation, Face-to-Face Consultation
- Where
- United Kingdom
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Abortion, Missed
Vaginal Misoprostol In Management Of First Trimester Missed Abortion.
The world health organization defined abortion or miscarriage as : the expulsion or extraction from its mother of a fetus or an embryo weighting 500 grams or less ,or any other wise product of gestation of any weight irrespective…
- Trial name
- NCT03148314
- Testing
- vaginal misoprostol, buccal/sublingual misoprostol
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Assiut University
Abortion in First Trimester
Choice of Modality of Follow up for Medication Abortion
This study will assess the impact of providing medication abortion-seeking clients a choice for follow-up in practice. Clients presenting at or less than 63 days pregnant (based on last menstrual period) at the study site for…
- Trial name
- NCT04056637
- Testing
- Choice of follow-up option, Multi-level pregnancy test
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Stanford University
Topical Heat Application for Intraoperative Abortion Pain Management
Applied Topical Heat as an Adjunct for Pain Control in First-Trimester Surgical Abortionl
Paracervical blocks are routinely used in first trimester surgical abortions and are a proven method for decreasing procedural pain.
- Trial name
- HAPPE (NCT02536235)
- Testing
- heat
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of Greater New York
First Trimester Abortion, Surgical Abortion
New Cross-linked Hyaluronan Gel to Prevent Adhesion After USG-MVA: RCT
The objective of this prospective, randomized controlled study was to evaluate the effectiveness of this NCH gel in the prevention of IUA development as assessed by hysteroscopy after USG-MVA, in the treatment for first-trimester…
- Conditions
- First Trimester Abortion, Surgical Abortion, Miscarriage With Afibrinogenemia
- Trial name
- NCT05360186
- Testing
- MateRegen® gel (BioRegen)
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- Chinese University of Hong Kong
Hydatidiform Mole (Diagnosis), Abortion, Spontaneous
The Accuracy of Ultrasound Diagnosis of Hydatidiform Moles
This is a prospective observational study assessing which ultrasound findings are best at excluding a molar pregnancy in first trimester miscarriage.
- Conditions
- Hydatidiform Mole (Diagnosis), Abortion, Spontaneous, Missed Abortion, Incomplete Miscarriage
- Trial name
- NCT05516810
- Where
- 2 sites in United Kingdom
- Volunteers
- 500 people
- Sponsor
- King's College Hospital NHS Trust
First Trimester Abortion
Unexplained Early Miscarriage : Role and Prevalence of Lower Genital Tract Infections
The study group included 910 women who attended Fayoum university hospital gynecology outpatient clinic for postabortive evaluation.
- Trial name
- NCT03413774
- Testing
- vaginal swab
- Where
- Egypt
- Volunteers
- 1,850 people, healthy volunteers welcome
- Sponsor
- Cairo University
Placenta; Implantation
The Accuracy of Ultrasound in the Detection of Placenta Site in the First Trimester.
The investigators speculate that ultrasound examination in the first trimester can accurately detect placental location. By performing both transabdominal ultrasound and later hysteroscopy on women with a first trimester missed…
- Trial name
- NCT04579796
- Testing
- ultrasound exam, hysteroscopy diagnostic
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Miscarriage
Misoprostol in Termination of First Trimester Missed Abortion
The purpose of this study is to determine whether oral versus vaginal misoprostol is effective in termination of first trimester missed abortion and to compare between two different routes.
- Trial name
- NCT00797693
- Testing
- Misoprostol ( Cytotec) 200 microgram a tablet
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Hawler Medical University
Missed Abortion, Early Pregnancy Loss
GPT-Based Digital Assistant Support During Treatment for Induced Abortion or Missed Abortion
We have developed a digital assistant based on GPT (Generative Pre-trained Transformer) technology, trained specifically to provide empathetic, medically accurate, and guideline-based responses in Hebrew, tailored to the clinical…
- Conditions
- Missed Abortion, Early Pregnancy Loss, Abortion in First Trimester, Abortion, Medical
- Trial name
- NCT07856940
- Testing
- GPT-Based Digital Assistant
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Wolfson Medical Center
Missed Abortion
Letrozole Pretreatment With Misoprostol Versus Misoprostol Alone in Missed Abortion
This study compares the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of first-trimester pregnancy.
- Trial name
- NCT04217265
- Testing
- Letrozole then misoprostol
- Volunteers
- 200 people
- Sponsor
- Cairo University
Abortion, Induced
Comparison of the Safety of First Trimester Abortions Performed by Physicians and Non-Physicians in South Africa and Viet Nam.
There have been no studies in developing countries assessing the safety of midlevel providers (MLP) compared to physicians in performing first-trimester manual vacuum aspiration abortion.
- Trial name
- NCT00370487
- Volunteers
- 2,860 people, healthy volunteers welcome
- Sponsor
- World Health Organization
Pain, Medical Abortion
Methadone and Medication Abortion
Pain has been recognized to be the most common and predictable side effect of medication abortion, causing significant distress associated with the process.
- Trial name
- NCT04941443
- Testing
- Methadone Pill, Ibuprofen
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston Medical Center
Induced Abortion
Is Oxytocin Given During Surgical Procedure for Abortion Before 12 Weeks of Pregnancy Useful?
This is a randomized, single-blind study using oxytocin 5U i.v. during surgical abortion in one arm of the study, and no medication in the other arm of the study.
- Trial name
- oxystudien (NCT00540748)
- Testing
- oxytocin
- Where
- Norway
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Asker & Baerum Hospital
Incomplete Abortion, Intrauterine Contraception
Ideal Timing of Intrauterine Contraception Insertion After Medical Management of First Trimester Incomplete Abortion
Background: Unintended pregnancies continue to cause a public health threat in Low and Middle Income countries yet with restrictive abortion laws.
- Conditions
- Incomplete Abortion, Intrauterine Contraception, Misoprostol
- Trial name
- PAIC (NCT05343546)
- Testing
- Use of either copper T380A or Levonorgestrel LNG 52 IUS after medical management of first trimester incomplete abortion
- Where
- Uganda
- Volunteers
- 2,076 people
- Sponsor
- Makerere University