Clinical trials: Abortion, Second Trimester
Late Second Trimester Termination of Pregnancy
Vaginal Misoprostol and Foley Catheter for Late Second Trimester Termination of Pregnancy
Vaginal Misoprostol Versus Combined Low Dose Misoprostol Plus Foley Catheter for Late Second Trimester Termination of Pregnancy With Previous Multiple Cesarean Sections
- Trial name
- NCT02989324
- Testing
- MisoprostoL, Foley Catheter
- Where
- Egypt
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Termination of Pregnancy
Comparison of Surgical Versus Medical Termination of Pregnancy Between 13-20 Weeks of Gestation in Ethiopia
The purpose of the study is to determine the safety and effectiveness of dilation and evacuation for surgical abortion as compared to medical abortion
- Trial name
- NCT04602052
- Testing
- Dilation and evacuation
- Where
- Ethiopia
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- St. Paul's Hospital Millennium Medical College, Ethiopia
Abortion, Induced
Transvaginal Versus Transabdominal Digoxin Prior to Second-trimester Abortion
Current practice for the provision of late second trimester abortion (dilation and evacuation, or D\&E) often involves the administration of digoxin into the fetal compartment to induce fetal demise prior to the procedure.
- Trial name
- NCT02277249
- Testing
- Digoxin (transvaginal administration), Digoxin (transabdominal administration)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
To Evaluate the Impact of the Vaginal Ph and Acidification of Vaginal Misoprostol on Its Efficacy in Facilitating Induction of Mid-trimester Abortion.
Study of Effect of Vaginal ph and Acidification of Vaginal Misoprostol on Its Efficacy for Induction of Midtrimester Abortion
To evaluate the impact of the vaginal Ph and acidification of vaginal misoprostol on its efficacy in facilitating induction of midtrimester abortion.
- Trial name
- NCT01241045
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Second Trimester Abortion
Cervical Preparation With Mifepristone Prior to Osmotic Dilators
The investigators plan to study the role of mifepristone prior to the placement of cervical osmotic dilators to evaluate if the medication helps increase the number of dilators.
- Trial name
- NCT03714880
- Testing
- Mifepristone 200 MG
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Second Trimester Abortion
Laminaria Compared to Dilapan-S for Cervical Preparation Before Dilation and Evacuation at 18-24 Weeks of Gestation
Primary objective: To study the difference in dilation and evacuation (D\&E) procedure time following overnight cervical preparation with laminaria or Dilapan-S™.
- Trial name
- NCT02033083
- Testing
- Laminaria, Dilapan-S
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of Greater New York
Abortion in Second Trimester
Mifepristone and Misoprostol for Midtrimester Termination of Pregnancy in Uzbekistan
The primary goal is to examine the efficacy and feasibility of a mifepristone-misoprostol medical abortion regimen in terminating pregnancies 13-22 weeks in Uzbekistan.
- Trial name
- NCT02235155
- Where
- 3 sites in Uzbekistan
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion Early
Mid Trimester Abortion Effectiveness by Dilapan s
This study is done aiming to find out an effective method to induce second trimester abortion within a reasonable time and with the least possible cost and complications.
- Trial name
- NCT05147857
- Testing
- Dilapan s, Misoprostol
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Arrhythmia, ECG Changes
Intra Amniotic Injection of DIGOXIN for Feticide in Second Trimester Termination of Pregnancy
In second trimester abortion above 22 weeks the investigators usually inject intra-cardiac Kcl for feticide. Digoxin intra-amniotic injection has been described in the literature in doses of 1-1.5 mg.
- Conditions
- Arrhythmia, ECG Changes, Hypotension
- Trial name
- NCT01951079
- Testing
- Intra-amniotic injection of DIGOXIN
- Where
- 2 sites in Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Induction of Second Trimester Abortion
Use of Ulipristal Acetate in Induction of Second Trimester Missed Abortion
The aim of this work is to assess the effectiveness and safety of Ulipristal Acetate in the management of 2nd trimester missed abortion along with misoprostol in pregnant women with previous caesarean section versus the use of…
- Trial name
- NCT04989400
- Testing
- Ulipristal Acetate, Misoprostol
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Induced Abortion
Same-Day Mifepristone-Misoprostol Compared to Misoprostol Only for Surgical Abortion Cervical Preparation
A randomized double---blinded comparison of same---day mifepristone and misoprostol with misoprostol only for cervical preparation in second---trimester surgical abortion in 100 women at 14 0/7---19 6/7 weeks gestation.
- Trial name
- MMSAP (NCT02412618)
- Testing
- Mifepristone, Misoprostol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Second Trimester Abortion, Uterocervical Angle
The Role of Cervical Consistency Index and Uterocervical Angles in Medical Termination
The main aim of the investigator study is the success of predictivity cervical consistency index (CCI), anterior uterocervical angle (aUCA) and posterior uterocervical angle (pUCA) in second trimester terminations.
- Conditions
- Second Trimester Abortion, Uterocervical Angle, Cervical Consistency Index
- Trial name
- NCT06164067
- Testing
- abortus within 24 hours or 24-48 hours
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Abortion, Induced
Mifepristone and Misoprostol Versus Misoprostol Alone for Mid-trimester Termination of Pregnancy (14 - 21 Weeks LMP): A Randomized-controlled Double-blinded Trial
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00784186
- Testing
- mifepristone+misoprostol, misoprostol
- Where
- 2 sites in Vietnam
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Second Trimester Abortion
Mifepristone and Misoprostol Compared With Misoprostol Alone for Second Trimester Abortion
Mifepristone and Misoprostol Compared With Misoprostol Alone for Second Trimester Abortion - a Double Blinded Randomized Controlled Trial
- Trial name
- NCT03044093
- Testing
- Mifepristone, Misoprostol
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Abortion, Induced
Mifepristone Versus Laminaria for Cervical Ripening in Midtrimester Induction
Data from other countries have suggested that oral mifepristone used as a cervical ripening agent may decrease induction to delivery time in midtrimester inductions.
- Trial name
- NCT00383032
- Testing
- mifepristone
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Abortion, Second Trimester
Transcervical Balloon Compared to Osmotic Dilators Prior to Surgical Abortion
The purpose of this study is to determine whether a Foley balloon is similar to osmotic dilators for preparing the cervix prior to a second trimester abortion.
- Trial name
- NCT05099991
- Testing
- Single Foley Balloon, Dilapan-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Stanford University
Asherman Syndrome, Abortion Late
Prevalence of Intrauterine Adhesions After D&C With or Without Antiadhesion Gel After Abortion in Second Trimester.
Only patients who sign an informed consent will be included. Patients after a miscarriage in the 2nd trimester of pregnancy who need to perform an instrumental revision of the uterine cavity (RCUI, revisio cavi uteri…
- Trial name
- ADAB (NCT04671914)
- Testing
- Hyaluronic Acid 20 MG/ML Injectable Solution, Dilation and curretage
- Where
- 3 sites in Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Institute for the Care of Mother and Child, Prague, Czech Republic
Pregnancy Termination in Second Trimester
Nitrous Oxide Versus Intravenous Sedation for Anesthesia
This study is a multi-site, double-blinded, randomized, non-inferiority clinical trial of inhaled nitrous oxide with oxygen (N2O/O2) versus intravenous (IV) sedation, with fentanyl and midazolam, for pain management in adult…
- Trial name
- NOVIA (NCT02755090)
- Testing
- Nitrous Oxide, IV Saline
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Abortion, Induced, Abortion, Second Trimester
A Pilot Study of Priming Before Induction Termination of Pregnancy
Induction termination of pregnancy (second trimester abortion) has a median time of 14 hours from the start of medication (misoprostol) to expulsion of the fetus.
- Trial name
- NCT00495560
- Testing
- Addition of misoprostol 25 mcg 12 hours before induction
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Boston University
Abortion, Induced
Mifepristone and Misoprostol Versus Misoprostol Alone for Mid-trimester Termination of Pregnancy (14-21 Weeks LMP)
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00957346
- Testing
- Mifepristone+misoprostol
- Where
- Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects