Clinical trials: Abdominal Wall Hernia
Hernia, Direct Inguinal Hernia
Study on Effects of Defect Closure in Laparoscopic Repair of Direct Inguinal Hernia
The defect closure was found to have higher pain and less seroma formation at various intervals of time following TEP for moderate-large direct inguinal hernia.
- Conditions
- Hernia, Direct Inguinal Hernia, Seroma Following Procedure
- Trial name
- NCT06389331
- Testing
- closed the defect with barbed suture
- Where
- Nepal
- Volunteers
- 88 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Incisional Hernia, Surgical Site Infection
Prophylactic Mesh Reinforcement for Stoma Closure
In the current work we are aiming to compare between the mesh-reinforced stoma closure and the anatomical closure in terms of the risk of developing surgical site incisional hernia (SSIH),incidence of surgical site infection …
- Conditions
- Incisional Hernia, Surgical Site Infection, Postoperative Pain, Hospital Stay, Length of Stay in Hospital From Surgery to Discharge
- Trial name
- OASIS (NCT06157645)
- Testing
- Prolene mesh
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Congenital Diaphragmatic Hernia
Initiation of Resuscitation While Attached to the Cord With Congenital Diaphragmatic Hernia
This study aims to measure the cardio-respiratory physiological consequences of initiating resuscitation during placental transfusion (PT) with an intact umbilical cord in infants with congenital diaphragmatic hernia (CDH).
- Trial name
- INSPIRE-CDH (NCT03094039)
- Testing
- Ventilatory support while attached to the cord, Immediate cord clamping
- Where
- Canada
- Sponsor
- University of Alberta
Hernia, Ventral, Rectus Diastasis
Endoscopic eTEP Versus Open Rives-Stoppa
Observational cohort study (partially retrospective, partially prospective) comparing the endoscopic extended totally extraperitoneal prosthesis (eTEP) repair for midline abdominal hernias to open Rives-Stoppa repair (control).
- Trial name
- NCT05446675
- Testing
- Endoscopic eTEP, Open Rives-Stoppa
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- AZ Alma
Postsurgical Pain
Preliminary Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair
A Three-Part, Phase 1/2, Randomized, Double-blind, Placebo-Controlled, Adaptive Safety, Pharmacokinetics, and Preliminary Efficacy Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair
- Trial name
- NCT04774328
- Testing
- CA-008 (vocacapsaicin)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Concentric Analgesics
Inguinal Hernia Repair, Inguinal Hernia
Non-mesh Repair of Inguinal Hernia: Desarda Versus Darn
To compare the results of Desarda and Darn techniques in inguinal hernia repair in Assiut University Hospital.
- Trial name
- NCT06712212
- Testing
- Inguinal Hernias repair: Desarda, Inguinal hernia repair: Darn
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Bariatric Surgery Candidate, Hiatal Hernia
Safety and Feasibility of Liver Retraction With the Levita Magnetic Surgical System: Extended Magnetic Grasper Device
The purpose of this study is to evaluate the safety and effectiveness of the Extended Magnetic Grasper Device in patients undergoing bariatric and/or hiatal hernia procedures, as a liver retractor grasping the liver and/or the…
- Trial name
- NCT06432088
- Testing
- Extended Magnetic Grasper Device
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Levita Magnetics
Congenital Diaphragmatic Hernia
Engagement in Physical Activities and Sports in Adolescents With Diaphragmatic Hernia
The objective is to understand how a population of adolescents - who have undergone diaphragm surgery within their first month of life (i.e.
- Trial name
- CHASAM (NCT05666986)
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Inguinal Hernia, Chronic Pain
Chronic Pain After Inguinal Hernia Repair
Chronic pain after inguinal hernia repair has become a major concern. Although tension-free Lichtenstein technique is used and new lightweight meshes have been developed, still up to 40 % of patients complain of some kind of pain…
- Trial name
- GRIP-ME (NCT00820131)
- Testing
- selfgrip mesh, lightweight mesh with suture fixation
- Where
- 7 sites in Austria
- Volunteers
- 250 people
- Sponsor
- Medical University of Vienna
Congenital Diaphragmatic Hernia
Fetal Endoscopic Tracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia
The purpose of the study is to study the efficacy of fetal endoscopic tracheal occlusion (FETO) in cases of severe congenital diaphragmatic hernia (CDH).
- Trial name
- FETO (NCT05461222)
- Testing
- Balt "Goldballoon"
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yair Blumenfeld
Inguinal Hernia
Effect of Suture for Mesh Fixation in Lichtenstein Hernia Repair
The investigators want to evaluate the effect of suturing the mesh versus using a self-adhesive mesh for Lichtenstein hernia repair. Effect parameters include chronic pain.
- Trial name
- Dangrip (NCT00815698)
- Testing
- suture, no suture
- Where
- 5 sites in Denmark
- Volunteers
- 334 people
- Sponsor
- Jacob Rosenberg
Inguinal Hernia
Activity Restrictions After Inguinal Hernia Repair
This research is intended to be a pilot study to identify differences in outcomes for varied lifting and physical activity precautions following surgical repair of single-sided inguinal hernias.
- Trial name
- NCT05867134
- Testing
- Removal of postoperative lifting restrictions
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Hernia
Safety Study of MotifMESH (cPTFE) in Abdominal Surgery
This study will monitor surgically repaired large abdominal hernias requiring condensed fenestrated polytetrafluoroethylene mesh (cPTFE).
- Trial name
- NCT01364233
- Testing
- MotifMESH
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Medline Industries
Hernia
A Study of Complex Ventral Hernia Repair Utilizing the XenMatrix™ Surgical Graft With Component Separation
This will be an observational study designed to collect early, short- and long-term clinical outcomes of the XenMatrix™ Surgical Graft for complex ventral hernia repair.
- Trial name
- XenMatrix (NCT01305486)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- C. R. Bard
Hernia, Inguinal, Lidocaine
Lidocaine Infusion for Pain After Herniotomy
This study seeks to investigate lidocaine infusion to reduce occurrence of chronic postoperative pain at 3-month after inguinal herniotomy
- Conditions
- Hernia, Inguinal, Lidocaine, Pain, Postoperative, Chronic Pain
- Trial name
- LIPAH (NCT03673163)
- Testing
- Lidocaine, Control
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Guangzhou First People's Hospital
Inguinal Hernia
Neo-angiogenesis in Inguinal Henia Implant ProFlor
The investigation is aimed at specifically demonstrating the ingrowth of newly formed vascular elements within ProFlor, a 3D dynamic responsive implant for inguinal hernia repair
- Trial name
- NCT04541316
- Testing
- ProFlor inguinal hernia device
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Analgesia
Extended Delivery of Bupivacaine Study in Herniorrhaphy
This is a phase 4, randomized, open-label study of the efficacy, safety, and pharmacokinetics of bupivacaine administered as liposomal bupivacaine or continuous infusion via elastomeric pump following unilateral open inguinal…
- Trial name
- NCT04102267
- Testing
- Bupivacaine liposome injectable suspension, Bupivacaine HCl without epinephrine via continuous infusion
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Heron Therapeutics
Ventral and Ventral Insicional Hernia
LVHR Multicenter Study
The study aims to prove differences or equalities in outcome for patients operated with laparoscopic ventral hernia repair with different methods of fixation of mesh and with or without approximation of defect prior to…
- Trial name
- NCT00455299
- Testing
- Laparoscopic ventral hernia repair
- Where
- 2 sites in Norway
- Volunteers
- 156 people
- Sponsor
- Oslo University Hospital
Eventration
Utility of a Supraaponeurotic Mesh as Prophylaxis of the Midline Eventration After an Oncological Colorrectal Resection
Randomized prospective experimental study, in which the effect of a prophylactic mesh is assessed in the eventration rate diagnosed by CT at one year after surgery in patients with CRC who underwent elective intervention for…
- Trial name
- NCT03520465
- Testing
- DynaMesh®-CICAT longitudinal measure 10x35 cm
- Where
- Spain
- Volunteers
- 154 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Ventral Hernia
A Prospective, Observational Study Utilizing Phasix™ Mesh During Ventral and Incisional Hernia Repair Surgery
The objective of this study is to collect efficacy, safety and utility data with Phasix™ Mesh in ventral and incisional repair procedures by evaluating the following: 1.
- Trial name
- NCT01863030
- Testing
- Phasix mesh implant
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- John Roth
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