Clinical trials: Abdominal Surgery Complications
Postoperative Complication
Effect of Remote Ischemic Preconditioning on Postoperative Complications in Visceral Surgery
Remote Ischemic Preconditioning (RIPC) is mediated by intermittent brief episodes (5-10 minutes) of short ischemia in a limb (i.e. arm), followed by reperfusion.
- Trial name
- RIPC (NCT02375269)
- Testing
- RIPC with a tourniquet
- Where
- Switzerland
- Volunteers
- 526 people
- Sponsor
- University of Zurich
Intra-Abdominal Hypertension, Postoperative Complications
The Impact of Intra-Abdominal Pressure on Mortality and Morbidity in Patients Undergoing Open-Heart Surgery
This prospective observational study evaluated whether increased intra-abdominal pressure, meaning increased pressure inside the abdomen, is associated with postoperative complications and mortality in adults undergoing elective…
- Trial name
- NCT07752082
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
PostoperativePulmonaryComplications
A Multicenter Randomized Controlled Clinical Trial of the Impact of Minimally Invasive Abdominal Surgery Esophageal Pressure Monitoring Guided Individualized PEEP on Postoperative Pulmonary Complications in Obese Patients
The aim of this study is to compare the effect of individualized PEEP based on transmural lung pressure and fixed PEEP on postoperative pulmonary complications during laparoscopic or robotic abdominal surgery in obese patients.
- Trial name
- NCT06996288
- Testing
- Transpulmonary pressure-guided individualized PEEP
- Volunteers
- 180 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Intraoperative Awareness, Intraoperative Responsiveness During General Anesthesia
Evaluation of Intraoperative Awareness and Its Correlation With Processed EEG Biomarkers During Laparoscopic Surgery
This prospective observational cohort study aims to evaluate intraoperative responsiveness and possible intraoperative awareness in adult patients undergoing elective laparoscopic abdominal surgery under general anesthesia and to…
- Trial name
- NCT07831590
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Duzce University
Pre-Diabetes, Major Lung or Abdominal Surgery
Attenuating The Post-Operative Insulin Resistance And Promoting Protein Anabolism
Major surgery results in a stress- induced catabolic response, marked by post-operative insulin resistance, hyperglycemia and loss of body protein, which is associated with increased morbidity, mortality and adverse outcomes.
- Conditions
- Pre-Diabetes, Major Lung or Abdominal Surgery, Insulin Resistance
- Trial name
- NCT02393573
- Testing
- Metformin
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Sarcopenia, Sarcopenic Obesity
Effects of Sarcopenia and Sarcopenic Obesity in Complex Abdominal Wall Surgery
The objective of our study is to evaluate the prevalence of sarcopenia and sarcopenic obesity in our surgical population and their relationship in postoperative complications after complex abdominal wall surgery and its influence…
- Conditions
- Sarcopenia, Sarcopenic Obesity, Incisional Hernia
- Trial name
- NCT04690179
- Volunteers
- 150 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Antibiotic Prophylaxis, Wound Infection
The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients
This study aims to investigate the impact of antibiotic prophylaxis on reducing wound infection rates following open repair of primary elective groin hernias in high-risk patients.
- Conditions
- Antibiotic Prophylaxis, Wound Infection, Groin Hernia
- Trial name
- NCT06576154
- Testing
- Cefazolin 1000 MG
- Where
- Syria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Perforated Peptic Ulcer, Fast Track Surgery
Impact of Abdominal Drains on the ERAS Pathway in Peptic Perforation
This study plans to assess the effect of placement of abdominal drains on the outcomes of ERAS (Enhanced recovery after surgery) protocol in the perioperative management of peptic perforation.
- Conditions
- Perforated Peptic Ulcer, Fast Track Surgery, Perforated Bowel, Post-Op Complication
- Trial name
- TUBELESS (NCT05368233)
- Testing
- ERAS protocol
- Where
- India
- Volunteers
- 92 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Epithelial Ovarian Cancer, Fallopian Tube Neoplasms
SUROVA - Surgery in Ovarian Cancer, Comparing Primary and Interval Cytoreductive Surgery
An international worldwide retrospective cohort observational study comparing primary cytoreductive surgery with neoadjuvant chemotherapy and interval cytoreductive surgery in patients with carcinoma of the ovary, fallopian…
- Conditions
- Epithelial Ovarian Cancer, Fallopian Tube Neoplasms, Peritoneal Neoplasms
- Trial name
- SUROVA (NCT06223763)
- Testing
- Cytoreductive surgery, Neoadjuvant chemotherapy, Adjuvant chemotherapy
- Where
- Spain
- Volunteers
- 5,000 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Peritoneal Carcinomatosis
Preoperative Inflammatory Markers Predict Postoperative Complications After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Colorectal Carcinomatosis
A retrospective study of a single-center prospective database of patients who underwent curative CRS-HIPEC for peritoneal carcinomatosis (PC) of colo-rectal cancer (CRC), between September 2012 and July 2023 at Reims…
- Trial name
- NCT06318793
- Where
- France
- Volunteers
- 166 people
- Sponsor
- CHU de Reims
Abdominal Surgery
Study To Check The Analgesic And Anti-Inflammatory Effects Of Atorvastatin In Patients Undergoing Abdominal Surgery
The study is planned to check the analgesic and anti-inflammatory properties of Atorvastatin in patients who will be undergoing abdominal surgery under spinal anesthesia.
- Trial name
- A4S (NCT00902967)
- Testing
- Atorvastatin
- Where
- India
- Volunteers
- 40 people
- Sponsor
- B. J. Medical College, Pune
Morbid Obesity, Acidosis
Intraoperative Fluid Management in Laparoscopic Bariatric Surgery
The objective of this study is to evaluate the effects of 'high' versus 'low' volume intraoperative fluid administration (Ringer Lactate, RL) on intra- and postoperative parameters, in obese patients undergoing laparoscopic…
- Conditions
- Morbid Obesity, Acidosis, Intra-Abdominal Abscess, Hemorrhage
- Trial name
- NCT00905502
- Testing
- Lactated Ringer's solution
- Where
- Israel
- Volunteers
- 107 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pain, Postoperative, Respiratory Depression
Effect of Postoperative Girdle Following Abdominal Surgery on Pulmonary Function, Mobilisation and Postoperative Pain
There is a considerable lack of knowledge in everyday surgical practice concerning treatment with a corset after laparotomy, in surgery for incisional hernia or as conservative treatment.
- Trial name
- NCT01517217
- Testing
- No girdle, Girdle
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Postoperative Pulmonary Complications (PPCs)
Impact of Lung Function Prehabilitation to Postoperative Pulmonary Complications
The aim of this study is to compare the effect of lung function prehabilitation to postoperative pulmonary complications on patient undergoing upper abdominal surgery treated in intensive care unit.
- Trial name
- NCT06862076
- Testing
- Lung Function Prehabilitation
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Abdominal Muscles/Ultrasonography, Adult
Medial Versus Traditional Approach to US-guided TAP Blocks for Open Inguinal Hernia Repair
Pain relief after open inguinal hernia repair could be improved by administration of TAP block or ilioinguinal/iliohypogastric nerve block. It is unclear which one works better.
- Conditions
- Abdominal Muscles/Ultrasonography, Adult, Ambulatory Surgical Procedures, Anesthetics, Local/Administration & Dosage
- Trial name
- NCT01589796
- Testing
- TAP block
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Stamford Anesthesiology Services, PC
Intraoperative Hypotension, Postoperative Pulmonary Complications (PPCs)
PRO STRESS Trial: Proactive Low-Dose Norepinephrine to Reduce Intraoperative Fluid Administration in Patients at High-Risk for Postoperative Pulmonary Complications Undergoing Laparoscopic Abdominal Surgery
Intraoperative hypotension is commonly treated with fluid administration; however, excessive fluid therapy may contribute to postoperative pulmonary complications.
- Conditions
- Intraoperative Hypotension, Postoperative Pulmonary Complications (PPCs), Fluid Over-load
- Trial name
- PRO STRESS (NCT07627360)
- Testing
- Norepinephrine
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Suez Canal University
Wound Infection, Surgical
Clinical Outcome in View of Surgical Site Infection (SSI) With Antibacterial Skin Sutures
Background: Poor wound healing and the development of surgical site infection (SSI) continue to occur and remain a significant cause of disability among operated patients.
- Trial name
- NCT01540279
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- University Hospital, Basel, Switzerland
Anesthesia
Psychological Assessment Before General Anesthesia (VeSPPA2018)
The level of preoperative anxiety can be related to the outcome of an operation and to the post operative patient management . The Dutch questionnaire APAIS (Amsterdam Preoperative Anxiety and Information Scale) is a useful tool…
- Trial name
- NCT03818464
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Parma
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Laparoscopic Abdominal Surgery
Pre-operative Carbohydrate Drink to Preserve Peri-operative Insulin Sensitivity
Enhanced Recovery after Surgery (ERAS) pathways include multiple evidence-based interventions delivered throughout the peri-operative period that aim to attenuate the surgical stress response and support rapid physiologic and…
- Trial name
- NCT02673502
- Testing
- simple carbohydrate drink, complex carbohydrate drink
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre