Clinical trials: Abdominal Aortic Aneurysms
Cardiovascular Diseases, Heart Diseases
Genetic Basis of Abdominal Aortic Aneurysm
To identify the genetic (major genes) and environmental factors responsible for the significant aggregation of abdominal aortic aneurysm (AAA) among relatives of affected individuals.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Aortic Aneurysm, Abdominal
- Trial name
- NCT00005526
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture, Abdominal Aortic Aneurysm, Without Mention of Rupture
BGP Stent as Bridging Stent in FEVAR
The objective of this clinical investigation is to evaluate, in a controlled setting, the safety and performance of the BeGraft Peripheral (BGP) balloon expandable covered stent Graft System (Bentley InnoMed, Hechingen, Germany)…
- Trial name
- NCT03987035
- Testing
- BeGraft Peripheral (BGP) Stent Graft System as bridging stent
- Where
- 9 sites in Germany
- Volunteers
- 103 people
- Sponsor
- Marc Bosiers, MD
Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm, Ruptured
Predicting Aneurysm Growth and Rupture With Longitudinal Biomarkers
First aim: PARIS study The main aim of the current study is to determine the association between abdominal aortic aneurysm (AAA) progression and the evolution of proteases and cytokines levels.To achieve this aim, we will…
- Trial name
- PARIS (NCT03320408)
- Where
- 2 sites in Netherlands
- Volunteers
- 790 people
- Sponsor
- Ron Balm
Aortic Aneurysm, Abdominal
The AAA Get Fit Trial: A Pilot Randomised Controlled Trial of Community Based Exercise in Patients With Abdominal Aortic Aneurysms
Rupture of abdominal aortic aneurysms(AAA) causes 12,000 deaths/year in the UK.1 Elective repair to prevent this carries a perioperative mortality of 4.5% for open surgery and 1% for endovascular repair.
- Trial name
- NCT02997618
- Testing
- Community based exercise programme, Control
- Volunteers
- 58 people
- Sponsor
- University of Manchester
Aneurysm
Brain and Abdominal Aneurysm Study
Aneurysmal subarachnoid hemorrhage (aSAH) is the most deadly kind of stroke. Each year, 40,000 Americans have SAH. Case-fatality approaches 60% and more than half of those who die do so before reaching the hospital.
- Trial name
- BAAS (NCT01420991)
- Where
- 2 sites in United States
- Volunteers
- 271 people
- Sponsor
- Mayo Clinic
Abdominal Aortic Aneurysms
Observatory of Screening Aneurysms of the Abdominal Aorta During Echocardiography. National Epidemiological Survey
Study of the prevalence of Abdominal Aortic Aneurysms (AAA) (> 3 cm) in patients with echocardiography (transthoracic or) during a specific day, with cardiologists in France.
- Trial name
- E2T3A (NCT01390740)
- Where
- France
- Volunteers
- 1,412 people
- Sponsor
- French Cardiology Society
Aortic Aneurysm, Abdominal
Cortisol Response to Adrenocorticotrophin (ACTH) in Acute Stress
Cortisol deficiency is diagnosed by the adrenocorticotrophin (ACTH) stimulation test. This test measures cortisol levels in the blood before and after giving an injection of ACTH.
- Trial name
- CRAAS (NCT00493389)
- Testing
- Adrenocorticotrophic hormone
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Ottawa
Abdominal Aortic Aneurysm (AAA)
Development of Novel Imaging Markers Predicting the Progression of Abdominal Aortic Aneurysm Using 3D Computed Tomography
Study purpose: This study will investigate anatomical factors associated with increased risk of major adverse aorta-related event and accelerated growth of abdominal aneurysm based on 3-dimensional analysis of CT images.
- Trial name
- NCT04333641
- Where
- South Korea
- Volunteers
- 323 people
- Sponsor
- Yonsei University
Abdominal Aortic Aneurysm
Immediate Management of the Patient With Rupture : Open Versus Endovascular Repair
The purpose of this trial is to assess whether a strategy of endovascular repair (if aortic morphology is suitable, open repair if not) versus open repair reduces early mortality for patients with suspected ruptured abdominal…
- Trial name
- IMPROVE (NCT00746122)
- Testing
- Open repair, EVAR
- Where
- 30 sites in Canada, United Kingdom
- Volunteers
- 613 people
- Sponsor
- Imperial College London
Vascular Disease
Efficacy of Patient Centred Information for Vascular Disease
This study aims to determine the usefulness of providing patients with web-based electronically accessed patient information when compared to the provision of written information leaflets.
- Trial name
- NCT01804972
- Testing
- Verbal and written information, Verbal and electronic information
- Where
- Ireland
- Volunteers
- 50 people
- Sponsor
- Mid Western Regional Hospital, Ireland
Abdominal Aortic Aneurysm
Evaluation of the Impact of Prehabilitation on Recovery Following Open Surgery for Abdominal Aortic Aneurysm
This is a pilot, prospective, randomized control trial that aim to provide a first estimation of the 3-month post-operative variation in the functional recovery of patients who benefited from an outpatient pre-habilitation…
- Trial name
- EPOP-AORTA (NCT05375292)
- Testing
- PREHABILITATION
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
Juxtarenal Abdominal Aortic Aneurysm
Safety and Efficacy Study of WeFlow-JAAA Stent Graft System for Complex Abdominal Aortic Aneurysm(GREAT Study)
A prospective, multi-center, objective performance criteria clinical trial to evaluate the safety and efficacy of WeFlow-JAAA stent graft system manufactured by Hangzhou Endonom Medtech Co., Ltd.
- Trial name
- NCT05179967
- Testing
- WeFlow-JAAA Stent Graft System
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.
Thoracoabdominal Aortic Aneurysms
Thoracoabdominal Artery Stent Graft System Exploratory Study
This study is designed as a single-center, prospective, single-arm, open-label, exploratory study. The objective is to evaluate the feasibility of Thoracoabdominal Artery Stent Graft System for endovascular treatment of…
- Trial name
- NCT06710938
- Testing
- The system includes the G-Branch™ thoracoabdominal aortic stent graft system, the peripheral vascular stent graft system, and the aortic extension stent graft system
- Where
- Germany
- Volunteers
- 11 people
- Sponsor
- Lifetech Scientific (Shenzhen) Co., Ltd.
Juxtarenal Aortic Aneurysm, Pararenal Aneurysm
Clinical Outcomes and Major Adverse Events in Patients Treated With Physician-Modified Fenestrated and Branched Stent Grafts
The purpose of this study is to evaluate safety and effectiveness of endovascular treatment of juxtarenal, pararenal and thoracoabdominal aortic aneurysms (with or without iliac artery involvement) using physician-modified stent…
- Conditions
- Juxtarenal Aortic Aneurysm, Pararenal Aneurysm, Thoracoabdominal Aortic Aneurysm
- Trial name
- NCT06526676
- Testing
- Cook Alpha TX2 Stent Graft, Cook Zenith TX2, and Cook Zenith Fenestrated Stent Graft
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Los Angeles
the Strength Properties of the Aorta in Vivo, the Strength Properties of the Aorta in Vitro
Comparison of the Biomechanical Properties of the Wall of an Aneurysmal-altered Abdominal Aorta According to the Results of in Vivo Ultrasound and an Associated Study of Strength Characteristics in Vitro
Identification of the regression model between the strength properties of tissue and its ultrasonic spectral characteristics.
- Conditions
- the Strength Properties of the Aorta in Vivo, the Strength Properties of the Aorta in Vitro, Regression Model of Aortic Strength Properties in Vitro and in Vitro
- Trial name
- NCT05634018
- Testing
- aneurysmectomy with sampling of a segment of the aneurysm wall
- Where
- 3 sites in Russia
- Volunteers
- 50 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Aortic Aneurysm, Abdominal, Aortic Diseases
Haemodynamic Response to Aortic Surgery
Open elective abdominal aortic surgery is a high risk procedure involving clamping of the aorta. Indications include abdominal aortic aneurysm (AAA) or aortic occlusive disease (AOD) causing lower limb ischaemia.
- Conditions
- Aortic Aneurysm, Abdominal, Aortic Diseases, Acute Kidney Injury
- Trial name
- NCT01704391
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Sygehus Lillebaelt
Aortic Aneurysm
Melatonin and Cardiac Outcome After Major Surgery
The purpose of this study is to assess whether treatment with melatonin can reduce cell damage and inflammatory stress response and thereby occurrence of myocardial injury after abdominal aortic surgery.
- Trial name
- NCT00315926
- Testing
- Melatonin
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Abdominal Aortic Aneurysm
Comparison of a Full Automatic Software With Standard Methods of Vessels Analysis
The treatment of aortic aneurysms is today based on different indicators (diameters, lengths, angles, volumes of the arteries) measured on CT scan images. Several indicators are time consuming and complicatated to measure.
- Trial name
- PRAEVA-2-LP (NCT05920317)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Nurea
Abdominal Aortic Aneurysms
A Multicenter, Open Label, Prospective, Non-Randomized Study Of INCRAFT™ In Subjects With AAA (INNOVATION)
This study is a multi-center prospective, open label, non-randomized investigation of INCRAFT™ in subjects with abdominal aortic aneurysms. The study will enroll up to 60 subjects in up to 7 sites in Germany and Italy.
- Trial name
- INNOVATION (NCT01106391)
- Testing
- Cordis AAA stent graft system "INCRAFT TM"
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Cordis US Corp.
Aortic Aneurysm, Abdominal
AAA-SHAPE Pivotal Trial: Abdominal Aortic Aneurysm Sac Healing and Prevention of Expansion
To determine the safety and effectiveness of IMPEDE-FX RapidFill to increase the percentage of subjects with shrinkage of the abdominal aortic aneurysm sac when used as an adjunct to on-label endovascular aneurysm repair (EVAR)…
- Trial name
- NCT06029660
- Testing
- IMPEDE-FX RapidFill Implants, EndoVascular Aneurysm Repair
- Where
- 49 sites in United States, France and 3 more
- Volunteers
- 180 people
- Sponsor
- Shape Memory Medical, Inc.