Clinical trials: ASD
Autism Spectrum Disorders (ASD)
Interventional rTMS for Improving Social Perception in Autism
Autism spectrum disorder (ASD) is a neurodevelopmental condition mainly characterized by difficulties in social interaction and social communication.
- Trial name
- IRIS-gaze (NCT07828457)
- Testing
- Neuromodulation by transcranial magnetic stimulation (TMS), Anatomo-functional MRI, Eye-tracking
- Where
- 2 sites in France
- Volunteers
- 16 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asperger's Disorder, Asperger Disorder
QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (Quantum AI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum AI/AGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Neurodevelopmental Disorders, Autism Spectrum Disorder (ASD)
Pai.ACT - An Artificial Intelligence Driven Chatbot Assisted ACT (Full Scale RCT)
Interventions for parents of children with NDD face two pivotal challenges. Firstly, many overlook the consequential influence of parenting stress, symptoms of parental anxiety and depression on the well-being of parent-child…
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder (ASD), Attention Deficit Disorder With Hyperactivity (ADHD)
- Trial name
- NCT06779422
- Testing
- Pai.ACT, Positive parenting advice
- Where
- Hong Kong
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators
This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder
The goal of this observational study is to evaluate cardiorespiratory and muscular fitness in children with obesity, with and without autism spectrum disorder (ASD), and examine how fitness relates to body measurements, body…
- Conditions
- Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators, Cardiometabolic Risk Factors, Metabolic Syndrome
- Trial name
- ROACH (NCT07804680)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Virginia
Autism Spectrum Disorder, ASD
A Phase 2A Trial of DT402 for Autism Spectrum Disorder
A Phase 2A Trial of DT402 Open-Label Study in Adults with Autism Spectrum Disorder
- Trial name
- NCT07303907
- Testing
- DT402 (R-enantiomer of 3,4-methylenedioxymethamphetamine (MDMA))
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Definium Therapeutics US, Inc.
Autism Spectrum Disorder (ASD)
Effectiveness of Dance Therapy for Students With Mild Autism Spectrum Disorder in China
This study aims to evaluate the effectiveness of Dance Movement Therapy (DMT) in improving social play, emotional regulation, group skills, and communication skills among students with mild autism in China.
- Trial name
- NCT07800026
- Testing
- Dance Movement Therapy (DMT), Regular Art Class (RAC)
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Universiti Putra Malaysia
Heart Diseases, ASD - Atrial Septal Defect
Abbott Structural Heart Device Registry
The Abbott Structural Heart (SH) Registry is being conducted to confirm the safety and performance of Abbott's SH devices in a post-market, real-world setting.
- Conditions
- Heart Diseases, ASD - Atrial Septal Defect, VSD - Muscular Ventricular Septal Defect, PFO - Patent Foramen Ovale
- Trial name
- SH-Registry (NCT06590467)
- Testing
- Amplatzer™ Occlusion Devices, Epic™ Surgical Tissue Heart Valve devices
- Where
- 36 sites in United States, Denmark and 8 more
- Volunteers
- 2,500 people
- Sponsor
- Abbott Medical Devices
Minimally Invasive Pediatric Cardiac Surgery, Pediatric Cardiac Surgery
Precision TOF-Guided Sugammadex Versus Spontaneous Recovery for Early Extubation in Minimally Invasive Pediatric Cardiac Surgery
This prospective observational cohort study evaluates a precision neuromuscular management strategy in pediatric patients undergoing minimally invasive cardiac surgery (MICS).
- Conditions
- Minimally Invasive Pediatric Cardiac Surgery, Pediatric Cardiac Surgery, Early Extubation Pathway, TOF-Guided Sugammadex Administration
- Trial name
- TOF (NCT07798011)
- Testing
- Sugammadex
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Dr. Nguyen Thi Thu Hang
Iatrogenic ASD, Mitral Regurgitation
Iatrogenic Atrial Septal Defect Gradient for Intraprocedural Success After M-teer
Transcatheter mitral edge-to-edge repair (M-TEER) has become an established minimally invasive therapy for patients with severe mitral regurgitation (MR) who are at high or prohibitive surgical risk.
- Trial name
- IASIS (NCT07798037)
- Testing
- M-TEER
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Hippocration General Hospital
Loudness Hyperacusis, Autism Spectrum Disorder (ASD)
Transitional Intervention for Hyperacusis in Autism
The main goal of this clinical trial is to evaluate the effectiveness, benefits, and post-treatment persistence of an intervention for loudness hyperacusis in adults with autism spectrum disorder (ASD).
- Conditions
- Loudness Hyperacusis, Autism Spectrum Disorder (ASD), Hyperacusis
- Trial name
- TIHA (NCT07798297)
- Testing
- Transitional Intervention for Hyperacusis in Autism
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Central Florida
Autism Spectrum Disorder, Autism
Pepea Pamoja: Cluster-Randomized Trial for Caregivers of Children With Autism in Kenya
Pepea Pamoja is a ten-session, group-based caregiver intervention designed to improve caregiver well-being and strengthen caregivers' ability to support communication and positive behavior in children with autism.
- Conditions
- Autism Spectrum Disorder, Autism, ASD
- Trial name
- NCT07259044
- Testing
- Professionally-facilitated groups, Peer-facilitated groups
- Where
- Kenya
- Volunteers
- 240 people
- Sponsor
- Indiana University
Attention Deficit Disorder With or Without Hyperactivity (ADHD), Autism Spectrum Disorder (ASD)
Characterize the Links Between Sleep, Emotional Dysregulation and Learning in Neurodevelopmental Disorders.
The aim of this protocol is to disentangle the links between symptoms of emotion dysregulation, sleep disorders and cognitive deficits by measuring the effects of an emotional induction task on childrens' sleep with autism…
- Trial name
- SOM-EMO-TND (NCT06479668)
- Testing
- Trier Social Stress Task
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD)
L-theanine and Paraxanthine for Cognitive Improvement in Adults With ADHD and ASD
This pilot study will test whether combining L-theanine and paraxanthine improves sustained attention, inhibitory control, and overall cognition in adults with ADHD and ASD.
- Trial name
- NCT07189442
- Testing
- L-theanine and paraxanthine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Texas Tech University Health Sciences Center
Autism Spectrum Disorder (ASD, Autism
Assessing Outcomes of Three Different Museum-based Social Prescription Programs in Autistic Adults
This study will examine whether visiting the National Taiwan Museum can support the social and emotional well-being of autistic adults.
- Conditions
- Autism Spectrum Disorder (ASD, Autism, Autistic Spectrum Disorder (ASD)
- Trial name
- NCT07768332
- Testing
- Independent museum visit, Guided museum visits and group discussions, Museum visit with a friend
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder (ASD
Effectiveness of DIR/Floortime™ in Children With Autism Spectrum Disorder
This randomized controlled trial evaluates the efficacy of Integrated DIR/Floortime™ in improving functional emotional development and adaptive behavior in children aged 4-12 years with Autism Spectrum Disorder (ASD).
- Trial name
- DIR-ASD (NCT07758465)
- Testing
- DIR/Floortime, Standard therapy
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Fatima Tabassum
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Dance, Yoga, And Mindful Movement Training For ASD
The goal of this study is to learn if a dance, yoga, and mindful movement program can improve the lives of adults with autism spectrum disorder (ASD).
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism
- Trial name
- NCT07758088
- Testing
- Yoga, dance and Mindful Movement
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- USC Glorya Kaufman School of Dance
PTEN, ASD
Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations
The purpose of this study is to determine cross-sectional and longitudinal medical, behavioral, and cognitive differences between PTEN ASD and other groups, as well as to identify cognitive, neural systems, and molecular…
- Conditions
- PTEN, ASD, Autism, Macrocephaly
- Trial name
- NCT02461446
- Where
- 5 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder (ASD)
Promoting Physical Activity Among Young Children With Autism
Higher amounts of physical activity are linked to multiple health benefits including improved cognition, academic success, and classroom behavior for children.
- Trial name
- NCT07747129
- Testing
- Wellness Enhancing Physical Activity for Young Children (WE PLAY), Non-Physical Activity Online Training
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Northeastern University
7q11.23 Microduplication Syndrome (7DUP), Autism Spectrum Disorder (ASD)
Characterization of the Natural History of Microduplication Syndrome 7q11.23
7q11.23 duplication syndrome (7q duplication syndrome/7DUP) is caused by a microduplication of the 7q11.23 chromosomal region, encompassing 26-28 genes, including the GTF2I gene.
- Conditions
- 7q11.23 Microduplication Syndrome (7DUP), Autism Spectrum Disorder (ASD), Neurodevelopmental Disorders (NDD)
- Trial name
- HINADU7 (NCT07469566)
- Testing
- clinical assessment, Parental questionnaires, Cognitive assessment
- Where
- 2 sites in France
- Volunteers
- 15 people
- Sponsor
- Hospices Civils de Lyon
Autism Spectrum Disorder (ASD)
Suramin for the Treatment of Autism Trial: KZ101 in a Male Pediatric Population With Autism Spectrum Disorder (ASD)
Suramin has been found to correct the symptoms, metabolism, and brain synaptic abnormalities in two classical genetic and environmental mouse models of autism.
- Trial name
- STAT-2A (NCT06866275)
- Testing
- KZ101
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Children's Hospital of Orange County