Clinical trials: AI Chatbot
Vaccination Hesitancy
The Effectiveness of Conversational AI Service (Chatbot) Utilization on Vaccine Confidence
The primary objective of this study is to develop and evaluate a conversational AI service (chatbot) on social media platforms to obtain accurate and up-to-date vaccine information, and assess the impact of chatbot usage on…
- Trial name
- NCT05424952
- Testing
- Conversational AI Service (Chatbot)
- Where
- 3 sites in Hong Kong, Singapore and 1 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Sarcoma
Information-providing Chatbot
This study aims to develop and examine the feasibility and preliminary effectiveness of an AI-based sarcoma chatbot building on ChatGPT (ASCC) to address the information needs of sarcoma patients.
- Trial name
- NCT07505732
- Testing
- ASCC (sarcoma-specific AI chatbot), Routine Clinical Care
- Volunteers
- 78 people
- Sponsor
- The Hong Kong Polytechnic University
Social Needs Status, Unmet Health-Related Social Needs and Access to Community Resources
AI-Based Personalized Health and Self-Care
The goal of this clinical trial is to learn if the DAPHNE chatbot can improve caregiver engagement, usability, and integration of social care support tools into clinical workflows in caregivers of pediatric patients receiving…
- Conditions
- Social Needs Status, Unmet Health-Related Social Needs and Access to Community Resources, Primary Health Care and Access to Primary Care, Technology Use to Support Caregivers
- Trial name
- NCT07168382
- Testing
- DAPHNE Chatbot Intervention, Standard HRSN Screening and Referral (Usual Care)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Emre Sezgin
Diabetes
AI-CIMCare Chatbot" to Enhance Complementary and Integrative Medicine (CIM)
Performance analysis of the AI-CIMCare Chatbot is an essential way to ensure its impact on the promotion of patient-based outcomes in patients with diabetes.
- Trial name
- AI-CIMCare (NCT07835061)
- Testing
- AI-CIMCare Chatbot, Empowerment Application for CAM Health Education
- Where
- Taiwan
- Volunteers
- 113 people
- Sponsor
- Chang Gung University of Science and Technology
Vaccine Hesitancy, COVID-19
The Impact of a Web-based Psychoeducation Programme with a Motivational AI Chatbot on Covid-19 Vaccine Hesitancy
Vaccine hesitancy is defined as 'delay in acceptance or refusal of vaccines, despite the availability of vaccine service' and was named one of the top ten global health threats by the World Health Organization in 2019.
- Trial name
- NCT05531058
- Testing
- AI-driven Vaccine Communicator, Self-learning of COVID-19 vaccine knowledge
- Where
- Hong Kong
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Artificial Intelligence (AI), Clinical Reasoning
AMIE's Clinical Conversational Abilities in an Urgent Care Setting
The purpose of this study is to determine the feasibility of a conversational artificial intelligence (AI) system to have a meaningful clinical conversation with a patient prior to an urgent care visit with their primary care…
- Trial name
- NCT06911398
- Testing
- Articulate Medical Intelligence Explorer (AMIE)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Alcohol-Related Liver Disease
A Large Language Model-based Chatbot for Alcohol Reduction in Patients With Metabolic Alcohol-Related Liver Disease
The goal of this pilot randomized controlled trial is to evaluate the trial feasibility and acceptability of LLM-based chatbot for reducing alcohol use among patients with metabolic alcohol-related liver disease.
- Trial name
- NCT07450144
- Testing
- LLM-based chatbot, Telephone counseling, Alcohol Brief Intervention
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Mild Cognitive Impairment (MCI), Social Isolation
AI-CONECT: A Conversational AI for Early Dementia Prevention in Socially-Isolated Older Adults
This randomized controlled trial examines the mechanisms of conversational AI-based interventions for early dementia prevention in socially isolated older adults.
- Trial name
- AI-CONECT (NCT07701668)
- Testing
- AI-based conversational intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Eating Disorders, Anorexia Nervosa
Developing an Artificial Intelligence (AI) Chatbot for Adolescents and Young Adults With Eating Disorders
The goal of this study is to develop and refine an artificial intelligence (AI)-powered Exposure Therapy for Eating Disorders chatbot web-app that effectively engages adolescents and young adults and decreases anxiety about…
- Conditions
- Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- NCT07237607
- Testing
- "Exp-ED" Digital Exposure-Therapy Chatbot app
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Cancer, Psychosocial Distress
Psychosocial Effects of a Trauma-Informed Artificial Intelligence-Supported Chatbot in Adults Newly Diagnosed With Cancer
The goal of this clinical trial is to evaluate whether a trauma-informed, artificial intelligence-supported chatbot can reduce psychological distress and unmet psychosocial needs in adults newly diagnosed with cancer.: Does the…
- Conditions
- Cancer, Psychosocial Distress, Trauma and Stress Related Disorders, Anxiety
- Trial name
- NCT07583069
- Testing
- Trauma-Informed AI-Supported Chatbot
- Volunteers
- 62 people
- Sponsor
- Koç University
Thyroid Cancer
Development and Application of an AI Chatbot for Perioperative Health Education in Thyroid Cancer Patients
The goal of this clinical trial is to evaluate the usefulness and effectiveness of a newly developed artificial intelligence (AI) chatbot for health education in thyroid cancer patients during the period around their surgery (the…
- Trial name
- NCT07634978
- Testing
- Routine Perioperative Health Education, Coze-Based AI Chatbot Health Education
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Health Behaviors, Artificial Intelligence (AI)
AI Chatbot-Based Learning on Dry Eye and Eye Strain Knowledge
The aim of this project is to evaluate the effectiveness of using chatbots for patient education about dry eye disease. The study will examine how the chatbot affects patients' levels of information, managing symptoms, and…
- Conditions
- Health Behaviors, Artificial Intelligence (AI), Chatbot, Dry Eye
- Trial name
- NCT06785155
- Testing
- Chatbot group, website assisted
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Hyperglycaemia, Hypertension
Developing an AI Pharmacy Chatbot for the Population of Hong Kong
The primary objective of this study is to is to develop a conversational AI service (chatbot) in Hong Kong to assist patients and caregivers with inquires related to Hospital Authority (HA)-prescribed medications, and to evaluate…
- Conditions
- Hyperglycaemia, Hypertension, Hyperlipidaemia, Artificial Intelligence (AI)
- Trial name
- NCT07037563
- Testing
- An AI pharmacy chatbot offering information related to HA-prescribed medication for hyperglycaemia, hypertension, and hyperlipidaemia
- Where
- 2 sites in Hong Kong
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Healthy
Chatbot Intervention Effects on Resting-State Brain Function in Anhedonia
The main aim of the present study is to investigate the effects of a Motivational Interviewing-based artificial intelligence chatbot on resting-state brain function in college students with elevated anhedonia and depressive…
- Trial name
- NCT07665216
- Testing
- MI Chatbot Interaction, Active Control Chatbot Interaction
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Epilepsy, Seizure
AI-Based Mobile Intervention on Medication Non-Adherence and Transition
This study aims to examine whether the AI-personalized version of the Medilepsy® app is more effective than the non-AI (standard version without AI personalization) can improve key outcomes, such as medical adherence and…
- Trial name
- NCT07445074
- Testing
- Medilepsy® Chatbot AI-Enhanced, Medilepsy® Chatbot Standard
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Central Florida
Physical Activity
Self-directed Use of Resources for Physical Activity
This is a pilot RCT examining physical activity outcomes at 3 months across 3 conditions: use of large language model (LLM) fully self-directed; use of LLM with guidance; and use of online tools to help with sleep.
- Trial name
- CHARGE (NCT07654868)
- Testing
- LLM alone, LLM enhanced, Sleep promotion
- Volunteers
- 39 people
- Sponsor
- University of Florida
Cancer
Artificial Intelligence-Powered Support For Quality Of Life Improvement In Participants With Cancer
This research study is for people who are diagnosed with cancer and are receiving treatment for cancer who may benefit from psychotherapy.
- Trial name
- NCT07167056
- Testing
- Standard of Care Psychotherapy, WYSA App
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Case Comprehensive Cancer Center
Healthy
Building Cognitive Resilience to Vaccine Misinformation Using AI in Europe
This multi-country trial evaluates an AI chatbot designed to counter cognitive biases and inoculate parents against vaccine misinformation, embedded within a large survey across five European countries (n=5,000).
- Trial name
- NCT07551986
- Testing
- AI-driven chatbot, Social media infographic
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Behavior, Health
A Relational Artificial Intelligence (AI) Chatbot for App-Based Physical Activity Promotion
This study aims to empirically test the theoretical mechanisms of relational perceptions in the context of building and testing a relational artificial intelligence (AI) chatbot for improving physical activity (PA) behaviors…
- Trial name
- NCT05794308
- Testing
- Non-Relational Chatbot Physical Activity Intervention, Relational Chatbot Physical Activity Intervention
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Psychological Stress, Perceived Stress
A Persian AI-Based CBT Chatbot and Voice Analysis System for Managing Perceived Stress
This pilot randomized controlled trial aims to evaluate a Persian-language artificial intelligence (AI)-based cognitive behavioral therapy (CBT) chatbot designed to support adults in managing perceived stress.
- Trial name
- PersianAI-CBT (NCT07840469)
- Testing
- Persian AI-Based CBT Chatbot, Active Mental Health Content
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Hamid Reza Marateb