Clinical trials: AI (Artificial Intelligence), open to volunteers
Cancer, Prostate Cancer
Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology
This prospective study will test artificial intelligence (AI) and machine learning (ML) decision support tools. This tool is designed to help doctors, physicists and other staff during pre-treatment peer review, a step where…
- Trial name
- NCT07463833
- Testing
- The Artificial Intelligence (AI)/ Machine Learning (ML) contribution to treatment planning
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Ulcerative Colitis (UC)
AI-driven Narrow-band Imaging Score for Disease Assessment and Outcome Prediction in Ulcerative Colitis
This international multicentre prospective study aims to develop a new simple score using enhanced endoscopic techniques which focus on the vascular features of the colon and reliably distinguish between a quiescent and a mild…
- Trial name
- MONET (NCT06709209)
- Testing
- Colonoscopy after bowel cleansing, Intestinal biopsies, blood sampling
- Where
- 11 sites in Belgium, Germany and 4 more
- Volunteers
- 300 people
- Sponsor
- University College Cork
Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities, Overweight (BMI > 25)
AIM-WEIGHT: AI-Guided Microbiome-Targeted Nutritional Intervention for Weight Loss
AIM-WEIGHT is a clinical study evaluating whether a fixed microbiome-targeted nutritional supplement can support weight loss in adults with overweight or obesity who do not have prediabetes or diabetes.
- Trial name
- AIM-WEIGHT (NCT07736547)
- Testing
- AI-Guided Microbiome-Targeted Nutritional Supplement, Lifestyle counselling
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Varol TUNALI
Coronary Artery Disease
AI-Based CT Analysis of Coronary Plaque Evolution
This retrospective, multicenter, observational study will evaluate an artificial intelligence-based system for quantitative assessment and risk stratification of coronary atherosclerotic plaque.
- Trial name
- AI-CT-PLAQUE (NCT07886996)
- Where
- 5 sites in China
- Volunteers
- 326 people
- Sponsor
- Zhejiang Hospital
Hypogonadism, Male, Secondary Hypogonadism
AIM-TEST: Microbiome-Targeted Nutrition for Functional Secondary Hypogonadism
AIM-TEST is a randomized, double-blind, placebo-controlled clinical trial evaluating whether an AI-guided, microbiome-targeted nutritional intervention can increase the body's own testosterone production in men aged 30-65 years…
- Trial name
- AIM-TEST (NCT07761546)
- Testing
- Fixed-Formula Microbiome-Targeted Oral Nutritional Supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Varol TUNALI
NSCLC (Non-small Cell Lung Cancer), Artificial Intelligence (AI)
Artificial Intelligence-based Model for the Prediction of Occult Lymph Node Metastasis and Improvement of Clinical Decision-making in Non-small Cell Lung Cancer
This nationwide, multicenter observational study aims to develop and validate a multimodal artificial intelligence (AI) model for detecting occult lymph node metastasis in early-stage non-small cell lung cancer (NSCLC) patients.
- Conditions
- NSCLC (Non-small Cell Lung Cancer), Artificial Intelligence (AI), Lymphnode Metastasis
- Trial name
- NCT06684418
- Testing
- chest enhanced CT
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Fudan University
Lung Nodule
AI-based Low Dose CBCT Reconstruction for Clinical Application
The goal of this clinical trial is to learn if AI-based low dose CBCT reconstructed images can guide lung puncture effectively. The main questions it aims to answer are: 1.
- Trial name
- NCT06831617
- Testing
- AI-based low dose CBCT reconstructed images system, Conventional CBCT images system
- Where
- 3 sites in China
- Volunteers
- 400 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Knee Arthroplasty, Total
Impact of Exercise Access on Physio Outcomes Post Knee Replacement
To stay strong, patients should do some strength training at least twice a week. However arthritic pain can limit walking and activity. The wait for knee surgery can be long, which can lead to loss of muscle strength.
- Trial name
- KEMTAI (NCT07502040)
- Testing
- Kemtai Digital App, NHS standard care
- Volunteers
- 40 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Lung Cancer (Diagnosis)
Predicting Immunotherapy Response and Survival of Lung Cancer Patients Using Artificial Intelligence and Radiomics (Radiology-AI-Lung)
CT imaging data from lung cancer (NSCLC and SCLC) patients prior to the initiation of immunotherapy (and possibly also after treatment) will be collected.
- Trial name
- NCT07059923
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Otitis Media Acute, Otitis Media Effusion
Gamified Training and AI Support for Improving Ear Infection Diagnosis in Primary Care
Acute otitis media (AOM), or middle ear infection, is one of the most common childhood infections and a leading cause of antibiotic prescribing in primary care.
- Trial name
- NCT07246551
- Testing
- AOM Dx Trainer (gamified educational program), No Intervention - Standard Care
- Volunteers
- 200 people
- Sponsor
- Vastra Gotaland Region
Intraductal Papillary Mucinous Neoplasm of Pancreas, Pancreatic Neoplasms
Real-Time AI During Pancreatoscopy for Detection of Pancreatic Neoplasia
This prospective pilot study will evaluate the diagnostic performance of a previously validated artificial intelligence (AI) model when applied in real time during digital per-oral pancreatoscopy (POPS).
- Trial name
- NCT07809841
- Testing
- AIWorks-Cholangioscopy Real-Time Artificial Intelligence Model
- Where
- Ecuador
- Volunteers
- 60 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Multiple Chronic Conditions, Patient Engagement
AI-Augmented Motivational Interviewing Training for Primary Care
This study will examine the impact of training primary care providers (PCPs) in motivational interviewing (MI) using artificial intelligence (AI) to augment the training process.
- Conditions
- Multiple Chronic Conditions, Patient Engagement, Burnout, Professional, Motivational Interviewing
- Trial name
- AIM-PC (NCT06597123)
- Testing
- Basic AI (artificial intelligence)-Augmented Motivational Interviewing Training, Plus AI (artificial intelligence)-Augmented Motivational Interviewing Training
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Wright State University
Cancer of Prostate
Artificial Intelligence 3D Augmented Reality Robot-Assisted-Radical- Prostatectomy v.s. no3D Intervention
This is a prospective randomized multicenter study aimed at comparing 3D AI-AR-RARP vs. no 3D, verifying the impact of this new technology on oncological and functional outcomes after the procedure.
- Trial name
- RIDERS (NCT06318559)
- Testing
- 3D Robot-assisted laparoscopic radical prostatectomy and pelvic lymphadenectomy
- Where
- 2 sites in Italy
- Volunteers
- 120 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Surgical Neoplasms, Abdominal Surgical Diseases
Prospective Collection and Registry Study of Multicenter, Multidisciplinary Surgical Minimally Invasive Videos
This is a prospective multicenter patient registry study. We continuously collect full-length intraoperative surgical videos from thoracoscope, laparoscope, hysteroscope, transcervical resectoscope, cystoscope, prostate…
- Conditions
- Surgical Neoplasms, Abdominal Surgical Diseases, Pelvic Surgical Diseases, Urologic Surgical Diseases
- Trial name
- VISION (NCT07752862)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Chinese Academy of Sciences
an Intelligent Teaching Agent for the "Epidemiology" Course of the MBBS Program, Students' Critical Thinking, Practical Ability and Learning Outcomes
Research and Application of an AI Agent-Based MBBS Course Assistant
Prior to the quasi-experiment, this study performed semi-structured interviews among Bachelor of Medicine and Bachelor of Surgery(MBBS) undergraduate students from the Belt and Road International Medical College, Zhejiang…
- Trial name
- NCT07752160
- Testing
- Socratic Agent for Guided Epidemiology, General LLM
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Cardiovascular Diseases, Coronary Artery Disease
AI-Powered Electrocardiography for Diagnosis and Prognostic Prediction in Cardiovascular Disease (AI-CVD): Multicenter Retrospective Study
This multicenter retrospective study aims to develop, validate, and clinically apply an artificial intelligence (AI)-powered electrocardiography (ECG) algorithm for the diagnosis and prognostic prediction of cardiovascular…
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Failure, Atrial Fibrillation (AF)
- Trial name
- AI-CVD (NCT07856472)
- Testing
- Retrospective ECG Data Analysis
- Where
- South Korea
- Volunteers
- 10,000 people
- Sponsor
- Inha University Hospital
Low Back Pain, Low Back Dysfunction
EFFICACY OF ARTIFICIAL INTELLIGENCE DRIVEN PROGRAM VERSUS TRADITIONAL PHYSICAL THERAPY PROGRAM IN PATIENTS WITH LOW BACK DYSFUNCTION
Low back dysfunction is one of the most common musculoskeletal disorders and is associated with pain, disability, and reduced quality of life.
- Trial name
- AI-LBD (NCT07749833)
- Testing
- AI-Driven Rehabilitation Program, Traditional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Basal Cell Carcinoma of Skin
Multimodal Imaging of Basal Cell Carcinoma: A Usability Study
The goal of this observational study is to evaluate the time efficiency and practical usability of three non-invasive skin imaging tools in adults (18 years and older) with basal cell carcinoma (BCC), the most common type of skin…
- Trial name
- NCT07803406
- Testing
- Non-invasive multimodal skin imaging
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Bispebjerg Hospital
Cardiovascular-kidney-metabolic Syndrome
AI Chatbot-Enabled ePRO Monitoring and Nurse-Led Self-Management for Early-Stage Cardiovascular-Kidney-Metabolic Syndrome
This randomized controlled trial will evaluate the effectiveness of an AI chatbot-enabled electronic patient-reported outcome (ePRO) monitoring and nurse-led self-management intervention for adults with early-stage…
- Trial name
- NCT07577284
- Testing
- AI chatbot-enabled nurse-led program., Usual Care
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University
Endotracheal Tube, Nasogastric Tube
AI-Assisted Chest X-Ray for Misplaced Endotracheal and Nasogastric Tubes and Pneumothorax in Emergency and Critical Care Settings
Background Advancements in artificial intelligence (AI) have driven significant breakthroughs in computer-aided detection (CAD) for chest X-ray imaging.
- Conditions
- Endotracheal Tube, Nasogastric Tube, Pneumothorax
- Trial name
- NCT06842043
- Testing
- AI-assisted model
- Where
- Taiwan
- Volunteers
- 10,900 people
- Sponsor
- National Taiwan University Hospital