Clinical trials: ACS - Acute Coronary Syndrome
Chest Pain, Diabetes Mellitus
Chest Pain Symptoms Differences Between Diabetic Patients and Non
Cardiovascular disease is the most severe cause of death among all non-infectious diseases and accountable for 17.5 million deaths in the world.
- Trial name
- chestpaindm (NCT06718374)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
ST-segment Elevation Myocardial Infarction (STEMI)
Fast Radial Pharmaco-invasive Strategy In ST Elevation Myocardial Infarction Trial
INTRODUCTION: The pharmaco-invasive strategy is a safe alternative to primary percutaneous coronary intervention (PCI) in patients with ST elevation acute myocardial infarction, who cannot be in the cathlab in less than 120…
- Trial name
- FARADMI (NCT04300582)
- Testing
- Cardiac catheterization standard strategy, Cardiac catheterization fast strategy
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo General Hospital
Coronary Artery Disease, Atherosclerosis of Coronary Artery
Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold System in the Treatment of Subjects With Long de Novo Lesions
The study objective is the assessment of safety and clinical performance of Freesolve 35- and 40-mm in de novo coronary artery lesions up to 38 mm length.
- Conditions
- Coronary Artery Disease, Atherosclerosis of Coronary Artery, Myocardial Ischemia, Ischemic Heart Disease
- Trial name
- BIOMAG-LL (NCT07091682)
- Testing
- Implantation of a Sirolimus-Eluting Resorbable Coronary Magnesium Scaffold
- Where
- 14 sites in Germany, Hungary and 5 more
- Volunteers
- 100 people
- Sponsor
- Biotronik AG
Acute Coronary Syndrome
Efficacy of Nursing Orientation to Reduce the Anxiety of Patients Undergoing Bed Bath
This study's general objective was to evaluate the efficacy of nursing orientation to reduce the anxiety of patients with acute coronary syndrome undergoing bed bath.
- Trial name
- NCT01724762
- Testing
- Nursing Orientation
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Federal University of São Paulo
Coronary Artery Disease
Influenza Vaccination in Prevention From Acute Coronary Events in Coronary Artery Disease - FLUCAD Study
Background: Influenza vaccination is recommended in patients (pts) with cardiovascular disease, however there is a shortage of clinical studies proving its protective effect on clinical course of coronary artery disease (CAD).
- Trial name
- NCT00371098
- Testing
- Influenza vaccination: Influvac (SolvayPharma)
- Where
- Poland
- Volunteers
- 658 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Renal Replacement Therapy, Renal Dialysis
A Clinical Trial of IntensiVE Dialysis
This study will assess clinical outcomes of extended weekly hours of haemodialysis (>= 24 hours per week) compared with standard hours of haemodialysis (<=18 hours/week) in people with ESKD.
- Conditions
- Renal Replacement Therapy, Renal Dialysis, End Stage Kidney Disease, End Stage Renal Disease
- Trial name
- ACTIVE (NCT00649298)
- Testing
- haemodialysis
- Where
- 40 sites in Australia, Canada and 2 more
- Volunteers
- 200 people
- Sponsor
- The George Institute
Acute Coronary Syndromes
REal World Advanced Experience of BioResorbable ScaffolD by SMart Angioplasty Research Team (SMART REWARD)
Current drug-eluting stents (DES) has demonstrated excellent clinical outcomes in patients with coronary artery disease. However, a continued risk of clinical events even several years after the procedure is reported.
- Trial name
- NCT02601404
- Testing
- Bioresorbable scaffold (BRS)
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease, Coronary Disease
Interventional Strategy for Non-culprit Lesions With Major Vulnerability Criteria at OCT in Patients With ACS
The INTERCLIMA (Interventional Strategy for Non-culprit Lesions With Major Vulnerability Criteria Identified by Optical Coherence Tomography in Patients With Acute Coronary Syndrome) is a multi-center, prospective, randomized…
- Conditions
- Coronary Artery Disease, Coronary Disease, Ischemic Heart Disease
- Trial name
- INTERCLIMA (NCT05027984)
- Testing
- Optical coherence tomography, iFR/FFR/RFR
- Where
- 34 sites in Greece, Italy and 2 more
- Volunteers
- 1,425 people
- Sponsor
- Centro per la Lotta Contro l'Infarto - Fondazione Onlus
Acute Coronary Syndrome
Telemedical vs. Conventional Prehospital Care in Acute Coronary Syndromes
Telemedically supported paramedic care of acute coronary syndromes was compared to a historical control period of solely conventional on-scene physician care.
- Trial name
- NCT03132935
- Testing
- Telemedical support
- Where
- Germany
- Volunteers
- 221 people
- Sponsor
- RWTH Aachen University
Acute Coronary Syndrome, Diabetes Mellitus
Platelet Aggregation in Diabetic Patients With Acute Coronary Syndrome Treated With Different Doses of Aspirin
Diabetes is an important risk factor of coronary atherosclerosis, and it's well known that platelets of diabetic patients are hyper reactive and so resistant to common antithrombotic therapy.
- Trial name
- DIABE-ASACS (NCT05293808)
- Testing
- aspirin 100 mg bis in die, aspririn 200 mg once daily, aspirin 100 mg once daily
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Federico II University
Acute Coronary Syndrome, Myocardial Infarction
Quantification and Description of the Increase in Serum Troponin Following Acute Coronary Syndrome
The new assay of troponins T (highly sensitive troponins) detects concentrations much lower than before. Few data are currently available on their kinetics during acute coronary syndrome, especially in regard to the correlation…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Unstable Angina
- Trial name
- QUANTUM (NCT01698021)
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Université de Sherbrooke
Acute Coronary Syndrome, Angiographic Evidence if Coronary Aneurysms
The Italian Coronary Artery Aneurysm and Ectasia In Patients With Acute Coronary Syndrome
The ITACA study is a prospective, observational no profit registry enrolling patients with Acute Coronary Syndrome and angiographic evidence of coronary aneurysms and/or ectasia.
- Conditions
- Acute Coronary Syndrome, Angiographic Evidence if Coronary Aneurysms, Ectasia
- Trial name
- ITACA (NCT05051917)
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Federico II University
Coronary Artery Disease, Acute Coronary Syndromes
Discovery of New Circulating Biomarkers of Coronary Atherosclerosis
The study hypothesis is that differential proteomic techniques can be used to discover new circulating biomarkers of coronary atherosclerosis in the blood of patients suffering from coronary artery disease (either stable or…
- Conditions
- Coronary Artery Disease, Acute Coronary Syndromes, Myocardial Infarction, Atherosclerosis
- Trial name
- NCT00430820
- Testing
- per intervention
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocardial Infarction (MI)
Contribution of Myocardial Perfusion Imaging in the Initial Assessment of Acute Coronary Syndromes Without ST Elevation for the Diagnosis of Myocardial Infarction or Differential Diagnoses
Patients with myocardial infarction require invasive treatment involving coronary angiography to confirm the diagnosis and, in most cases, treatment by angioplasty/stenting.
- Trial name
- APRICOT (NCT07112820)
- Testing
- perfusion ultrasound
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Acute Coronary Syndrome, Chest Pain
Database of Patients Undergoing Cardiac Computed Tomographic Angiography at William Beaumont Hospital (CT DATABASE)
The purpose of the study is to establish an overarching database of information containing historical, demographical, clinical, and intermediate and long-term outcome data from all William Beaumont Hospital (WBH) patients…
- Trial name
- CTDATABASE (NCT00922662)
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Kavitha Chinnaiyan
Acute Coronary Syndrome
Can Very Low Dose Rivaroxaban in Addition to Dual Antiplatelet Therapy (DAPT) Improve Thrombotic Status in Acute Coronray Syndrome (ACS) ACS
A prospective, randomised, open label study of 3 clinically licensed treatments for ACS to assess the effects of these treatments on blood tests of endogenous fibrinolysis.
- Trial name
- VaLiDate-R (NCT03775746)
- Testing
- Clopidogrel 75Mg Tablet, Rivaroxaban 2.5Mg Tablet, Ticagrelor 90Mg Tablet
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- East and North Hertfordshire NHS Trust
Acute Myocardial Infarction, Acute Coronary Syndrome
Improving Cardiac Rehabilitation Outcomes Through Mobile Case Management (iCARE)
The purpose of this research is to find out if doing cardiac rehab at home, or a mix of cardiac rehab at home and in the clinic, is as effective as coming in to the clinic for cardiac rehab.
- Conditions
- Acute Myocardial Infarction, Acute Coronary Syndrome, Stable Angina Pectoris, Percutaneous Coronary Intervention
- Trial name
- iCARE (NCT04938661)
- Testing
- Center-Based Cardiac Rehab, mHealth, Home-Based Cardiac Rehab
- Where
- 2 sites in United States
- Volunteers
- 206 people
- Sponsor
- Mayo Clinic
Acute Coronary Syndrome
Effect of Glucose-insulin-potassium Solution on Myocardial Protection During Off-pump Coronary Bypass Surgery in Patients With Acute Coronary Syndrome
Patients undergoing multivessel off-pump coronary bypass surgery (OPCAB) inevitably experience cumulative ischemia-reperfusion injury at myocardium.
- Trial name
- NCT01384656
- Testing
- GIK solution
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Yonsei University
Low Risk Acute Coronary Syndrome
Low Risk Acute Coronary Syndrome
A large number of patients are diagnosed with low risk ACS, and these individuals are at significant cardiovascular risk. Though guidelines recommend stress testing to manage low risk ACS patients, evidence supporting this…
- Trial name
- LOW ACT (NCT01703156)
- Testing
- Stress Test, No Stress Test
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Oklahoma
Acute Coronary Syndrome
Guided Optimisation of Long-term Disease rEduction in secoNdary Prevention of CVD
The goal of this observational study is to evaluate the implementation of a 'first-time-right' pharmacological treatment strategy in patients hospitalized with coronary artery disease.
- Trial name
- GOLDEN (NCT06637657)
- Testing
- No intervention (observational study)
- Where
- Netherlands
- Volunteers
- 5,586 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)