Clinical trials: ACL Surgery
Anterior Cruciate Ligament Injuries
How to Best Treat Anterior Cruciate Ligament Injuries
The project is a pragmatic registry-based RCT aiming to investigate ACL injury treatment. Study results will help fill knowledge gaps, facilitate shared decision making and strengthen patient treatment.
- Trial name
- NCT04770233
- Testing
- Early ACL reconstruction, Active rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 328 people
- Sponsor
- University Hospital, Akershus
Anterior Cruciate Ligament Injury
Single- vs. Double-Bundle ACL Reconstruction
The purpose of this double-blind, randomized clinical trial to compare outcomes of single-bundle (SB) to anatomic double-bundle (DB) ACL reconstruction.
- Trial name
- NCT01319409
- Testing
- Anatomic Double-Bundle ACL Reconstruction, Anatomic Single-Bundle ACL Reconstruction
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Pittsburgh
Anterior Cruciate Ligament Injury
Conditioning Brain Responses to Improve Thigh Muscle Function After Anterior Cruciate Ligament Reconstruction
The purpose of this study is to examine if thigh muscle weakness and the lack of muscle activation that accompanies ACL injury can be improved through a form of mental coaching and encouragement, known as operant conditioning.
- Trial name
- NCT03209531
- Testing
- Operant Conditioning, Control, Single Pulse Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Michigan
ACL Reconstruction
When do School-aged Patients Return to School After ACL Surgery?
We intend to survey school aged patients following ACL surgery on when they return to school. We will analyze independent variables to determine if any relationship exists that may influence the amount of time missed.
- Trial name
- NCT03929237
- Testing
- observe when return to school after surgery
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- St. Louis University
ACL Repair, Meniscectomy
Efficacy Study of Continuous Intraarticular Infusion in Patients Undergoing Arthroscopic Knee and Shoulder Operations
The aim of this study is to determine whether the continuous intraarticular infusion of local anesthetics in the postoperative period can improve analgesia and patients satisfaction after knee and shoulder arthroscopy.
- Conditions
- ACL Repair, Meniscectomy, Bankart Repair
- Trial name
- NCT00314457
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Children's Hospital of Philadelphia
Anterior Cruciate Ligament Reconstruction
Effectiveness of Kneehab in Strengthening the Quadriceps of Patients Post Anterior Cruciate Ligament (ACL) Reconstruction
Prospective, controlled, randomized, single blind study in patients undergoing rehabilitation following anterior cruciate ligament reconstruction. 96 patients were randomly assigned to one of three groups.
- Trial name
- NMES (NCT00737750)
- Testing
- Kneehab, Poli-Stim, Control
- Where
- Germany
- Volunteers
- 131 people
- Sponsor
- Bio-Medical Research, Ltd.
Anterior Cruciate Ligament Tear
Anterior Cruciate Ligament (ACL) Reconstruction: Single Bundle Versus Double Bundle
ACL tear is a common injury among athletes. The recommended treatment includes reconstruction of the ligament. The common reconstruction technique is single bundle reconstruction.
- Trial name
- NCT01025895
- Testing
- acl reconstruction - double bundle technique, acle reconstruction - single bundle technique
- Volunteers
- 60 people
- Sponsor
- Assaf-Harofeh Medical Center
ACL, Anterior Cruciate Ligament Injuries
Genicular Nerve Blocks for Anterior Cruciate Ligament Knee Surgery
The purpose of this randomized controlled trial is to assess a new analgesia regimen that includes the addition of genicular never blocks to our current standard regimen of peripheral nerve blocks, which includes an adductor…
- Trial name
- NCT05720949
- Testing
- Genicular Nerve Block with bupivacaine and preservative free dexamethasone
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Hospital for Special Surgery, New York
Anterior Cruciate Ligament Injury, Knee Injury
Comparison of Quadriceps and Semitendinosus Grafts in ACL Reconstruction Using Data From the Danish Knee Ligament Reconstruction Registry (DKRR)
This study looks at two different types of tendon (tissue) used in knee surgery to repair a torn anterior cruciate ligament (ACL), which is a common injury in active people.
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injury, Ligament Reconstruction, Sports Injuries
- Trial name
- NCT06980285
- Where
- Denmark
- Volunteers
- 2,500 people
- Sponsor
- Abdirahman Hassan Omar
Rupture of Anterior Cruciate Ligament
Multicenter Orthopaedics Outcomes Network for ACL Reconstructions
The purpose of this study is to determine the effect of modifiable risk factors on knee function, osteoarthritis, and re-rupture of the anterior cruciate ligament (ACL) following ACL reconstruction.
- Trial name
- NCT00463099
- Where
- 8 sites in United States
- Volunteers
- 3,294 people
- Sponsor
- Vanderbilt University Medical Center
Anterior Cruciate Ligament Reconstruction Rehabilitation, Strength Outcomes
Effect of Graft Type on Knee Muscle Strength After ACL Reconstruction
This prospective observational study will compare recovery after anterior cruciate ligament reconstruction using quadriceps tendon autograft or hamstring tendon autograft.
- Conditions
- Anterior Cruciate Ligament Reconstruction Rehabilitation, Strength Outcomes, Anterior Cruciate Ligament (ACL) Reconstruction Surgery
- Trial name
- GRAFT-ACL (NCT07523854)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hacettepe University
Anterior Cruciate Ligament Injuries
Wearable Vibration Effect on Biomechanics and Biomarkers After ACL Reconstruction
Anterior cruciate ligament (ACL) injuries account for up to 25% of knee injuries, it is estimated that 32,000-400,000 new cases of ACL tears occur in the USA every year.
- Trial name
- NCT05001594
- Testing
- Active vibratory knee device
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Technion, Israel Institute of Technology
ACL Tear, Post Operative Pain
Impact of Opioid Avoidance Protocol for ACL Reconstruction
This is a prospective, quasi-experimental, cohort study comparing patients treated with one of two postoperative pain management protocols.
- Trial name
- NCT06340932
- Testing
- Iovera, Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Matthew Varacallo
Anterior Cruciate Ligament Injury
Effects of Low-intensity Strength Training With Concomitant Blood Flow Restriction on Pain Perception in Patients With Anterior Cruciate Ligament Surgery
After surgical treatment of a tear of the anterior cruciate ligament, physiotherapeutic exercises are done as standard therapy. This is to achieve a rapid improvement in pain and knee function.
- Trial name
- BFR (NCT06699264)
- Testing
- Blood Flow Restriction Training, Training without BFR
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Praxisklinik Rennbahn AG
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction
Clinical and Functional Outcomes After ACL Reconstruction Versus Primary Repair
The anterior cruciate ligament (ACL) is the primary structure responsible for controlling anterior-posterior translation and rotational stability of the knee joint.
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction, Isokinetic Test
- Trial name
- NCT07318272
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gazi University
Total Knee Arthroplasty, Anterior Cruciate Ligament Reconstruction
Impact of Crutch Type on Gait and Functional Outcomes Post-knee Surgery
Study withdrawn
- Trial name
- NCT04258917
- Testing
- Study withdrawn
- Sponsor
- University of Calgary
Cruciate Ligament Rupture
Stability of the Knee Joint After Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction
The objective of this randomised cohort study was to evaluate the knee rotational stability after the single-bundle ACL reconstruction (SB) with addition of the ALL reconstruction and to compare it with the double-bundle ACL…
- Trial name
- NCT02993679
- Testing
- reconstruction of the ACL and anterolateral ligament
- Volunteers
- 60 people
- Sponsor
- Hospital Znojmo
Meniscus Injury, Meniscus Tear
Assessment of Quadriceps Femoris Muscle Function in Patients After Arthroscopic Knee Surgery in Outpatient Rehabilitation
The goal of this clinical trial is to learn if a high intensity magnetic field is an effective way to treat quadriceps muscle atrophy after knee arthroscopic surgery in adult patients.
- Conditions
- Meniscus Injury, Meniscus Tear, Arthroscopic Knee Surgeries, ACL Injuries
- Trial name
- NCT06870825
- Testing
- High-intensity Magnetic Field Muscle Stimulation, Transcutaneous Neuromuscular Electrical Stimulation
- Where
- Lithuania
- Volunteers
- 150 people
- Sponsor
- Lithuanian University of Health Sciences
Anterior Cruciate Ligament Rupture
LIBRE (Ligamys, Internal Bracing, REconstruction) Study: Comparing Three Surgery Techniques After an Acute ACL Rupture.
Single-blind, multi-centre, prospective, randomized controlled trial comparing Ligamys Anterior Cruciate Ligament (ACL) repair, Internal Bracing ACL repair and conventional ACL reconstruction for relative clinical efficacy and…
- Trial name
- LIBRE (NCT03441295)
- Testing
- Dynamic Intraligamentary Stabilization, Internal Brace Ligament Augmentation, ACL Reconstruction
- Where
- 3 sites in Belgium
- Volunteers
- 95 people
- Sponsor
- University Hospital, Antwerp
ACL Reconstruction, Meniscus Tears
A Comparison of Outcomes After Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) Surgery Using Semiconductor Fabric Products
The goal of this clinical trial is to determine the effect of semiconductor sleeves on the treatment of Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) arthroscopic surgery.
- Conditions
- ACL Reconstruction, Meniscus Tears, Anterior Cruciate Ligament Rupture
- Trial name
- NCT06979804
- Testing
- Semiconducting fabric sleeves, Non-semiconducting fabric sleeves
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Illinois Center for Orthopaedic Research and Education