Clinical trials: ACL Surgery
Anterior Cruciate Ligament Reconstruction
Effectiveness of Kneehab in Strengthening Quadriceps in Rehabilitation Post Anterior Cruciate Ligament (ACL) Reconstruction
Prospective, controlled, randomized, single blind study in patients undergoing rehabilitation following anterior cruciate ligament reconstruction. 96 patients were randomly assigned to one of three groups.
- Trial name
- NMES (NCT00738010)
- Testing
- Kneehab, Poli-Stim, Control
- Where
- Germany
- Volunteers
- 131 people
- Sponsor
- Bio-Medical Research, Ltd.
Anterior Cruciate Ligament Rupture
BFRT in Adolescents After ACL Reconstruction
This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR).
- Trial name
- NCT04390035
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Anterior Cruciate Ligament Injuries
Clinical and Radiological Evaluation of ACL Reconstruction Results
The study is intended to include all patients who will undergo surgical reconstruction of the anterior cruciate ligament (ACL). The patients will be monitored and evaluated preoperatively and also at 6 months and 1 years after…
- Trial name
- NCT05504018
- Testing
- ACL reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Samsun University
ACL - Anterior Cruciate Ligament Rupture
Microbiological Molecular Profile of the Knee Joint During Primary Reconstruction or Revision Surgery of the ACL
Anterior cruciate ligament (ACL) reconstructions are common surgical procedures, but a significant number fail for reasons that are not fully understood.
- Trial name
- INFECTIOGEN (NCT07009392)
- Testing
- NGS Analysis
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Anterior Cruciate Ligament (ACL) Reconstruction
Does Perioperative Pregabalin Reduce Postoperative Pain After Arthroscopic Anterior Cruciate Ligament Reconstruction Surgery Under Spinal Anesthesia?
The investigators hypothesize that perioperative oral administration of pregabalin would reduce postoperative pain and produce reduction in postoperative opioid consumption after anterior cruciate ligament (ACL) reconstruction .
- Trial name
- NCT03211728
- Testing
- pregabalin
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Yonsei University
Pain, Postoperative
A Multicentre, Double-Blind, Double-Dummy, Randomised Study of the Analgesic Efficacy and Safety of Valdecoxib Compared to Diclofenac Sodium in Patients Undergoing Knee Arthroscopy for Anterior Cruciate Ligament (ACL) Reconstruction
To demonstrate non-inferiority of valdecoxib 20 mg twice daily (BID) (with an initial loading dose of 40 mg followed by a second dose of 20 mg on the first day only) with diclofenac sodium delayed release 75 mg BID in analgesic…
- Trial name
- NCT00650598
- Testing
- valdecoxib, diclofenac
- Where
- 25 sites in Australia, Hong Kong and 7 more
- Volunteers
- 328 people
- Sponsor
- Pfizer
ACL Injury
A Prehab Strengthening Program Prior to ACL Surgery on Lower Limb Structure and Function
Atrophy and weakness are ubiquitous after a ACL rupture and associated with a worsened long-term recovery of individual capacities, despite surgery and rehabilitation.
- Trial name
- ACL-Strong (NCT05374382)
- Testing
- Strengthening, Conventional
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Université de Nantes
ACL Injury
Dietary Protein Intake and Rehabilitation From Anterior Cruciate Ligament Surgery
Protein supplementation may promote increases in strength and hypertrophy in the context of resistance training (RT) and reduce markers of inflammation, while sufficient levels of protein are necessary for healing certain wounds…
- Trial name
- NCT03614351
- Testing
- Protein (PROT), Control (CONT)
- Sponsor
- Wake Forest University Health Sciences
Arthroscopic Knee Surgery
Adductor Canal Block and Arthroscopic Knee Surgery, High Pain Responders
The investigators want to explore the analgesic effect of Adductor Canal Blockade (a peripheral nerve block) in high pain responding patients after arthroscopic knee surgery.
- Trial name
- NCT02001662
- Testing
- Intervention group, block no. 1 - Ropivacain, Control group: 1. block - saline
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Posttraumatic Osteoarthritis, Anterior Cruciate Ligament (ACL) Rupture
Synovial Fluid Withdrawal or PRP Injection For Acute ACL Tears and Cytokines
The purpose of this study is to determine what effects the withdrawal of excess knee joint fluid or the injection of a factor from the blood has on swelling after a sudden anterior cruciate ligament (ACL) rupture of the knee.
- Trial name
- NCT07142369
- Testing
- Synovial Fluid withdrawal at the preoperative clinic visit, Platelet-Rich Plasma (PRP) preparation and injection, Synovial fluid withdrawal at the time of surgery
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Rush University Medical Center
ACL - Anterior Cruciate Ligament Rupture
The Effect of Cognitive-Based Neuromuscular Exercises on Reaction Time, Joint Position Sense, Proprioceptive Force Sense and Balance in Individuals Who Had Anterior Cruciate Ligament Surgery
The aim of this study is to investigate the effects of cognitive-based neuromuscular exercises on increased reaction time, decreased joint position sense, reduced proprioceptive force sense, and balance problems in individuals…
- Trial name
- NCT06755398
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ertuğrul Demirdel
Anterior Cruciate Ligament Reconstruction
Operation ACL: Rehabilitation After Anterior Cruciate Ligament Reconstruction
Scientific Research Question Overall Purpose: Regarding rehabilitation after anterior cruciate ligament reconstruction (ACLR), there is a knowledge gap - a lack of evidence.
- Trial name
- NCT06318039
- Testing
- Novel program, Traditional program
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Linnaeus University
Anterior Cruciate Ligament Rupture
Effects of Corporal Visualisation Program of the Static and Dynamic Balance After an Operation of the LCA
The aim of this pilot study is to assess the feasibility of a RCT whose topic would be the effect of a motor imagery program on the postural control in persons who have undergone ACL plasty.
- Trial name
- NCT05081661
- Testing
- Motor Imagery Program
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- HES-SO Valais-Wallis
ACL Injury, ACL Sprain
Isoinertial Rehabilitation in Recovering Hamstring Strength Following Surgical Anterior Cruciate Ligament Reconstruction
The present experimental study aims to evaluate the effectiveness and tolerability of isoinertial strength training of the hamstrings using machines in patients with ACL-R during the intermediate post-intervention phases.
- Conditions
- ACL Injury, ACL Sprain, ACL Tear, Anterior Cruciate Ligament Rupture
- Trial name
- NCT06063915
- Testing
- Isoinertial training, Strength Training
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Università degli studi di Roma Foro Italico
Anterior Cruciate Ligament Injuries
Rate of Non-copers to Non-surgical ACL Treatment After 3 Months of Rehabilitation
The aim is to determine the sensitivity and specificity of a screening tool to identify patients who undergo ACL reconstruction (non-copers) after 3 months of standard rehabilitation following an anterior Cruciate ligament (ACL)…
- Trial name
- NCT04847258
- Testing
- Standard rehabilitation
- Where
- Denmark
- Volunteers
- 357 people
- Sponsor
- Vejle Hospital
Anterior Cruciate Ligament Injuries, Postoperative Pain
Multimodal Analgesia vs. Femoral Block in ACL Surgery
This study aims to compare the effects of a preemptive multimodal intravenous analgesia protocol and a femoral triangle block on early postoperative rehabilitation compliance in patients undergoing anterior cruciate ligament…
- Conditions
- Anterior Cruciate Ligament Injuries, Postoperative Pain, Pain, Postoperative
- Trial name
- MAPvsFTB (NCT06936995)
- Testing
- Preemptive Multimodal Intravenous Analgesia, Femoral Triangle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Ankara University
Anterior Cruciate Ligament (ACL) Tear, Sports Injuries in Children
Evaluation of Pain Management After Surgery When Using Nerve Blocks in the Pediatric Population
The goal of this randomized clinical trial is to determine if single-shot ropivacaine peripheral nerve blocks (PNB - perineural injections) for anterior cruciate ligament (ACL) reconstruction procedures in pediatric orthopaedic…
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Sports Injuries in Children, Analgesia, Pain, Postoperative
- Trial name
- NCT06559137
- Testing
- Ropivacaine 0.2% Injectable Solution
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Texas Scottish Rite Hospital for Children
ACL Surgery, Quadriceps Strength
KEA vs Towel for Early Quad Activation Post Anterior Cruciate Ligament Reconstruction
The goal of this clinical trial is to learn if a novel Knee Extensors Activation (KEA) device can improve quadriceps muscle activation in adults after anterior cruciate ligament (ACL) reconstruction surgery.
- Trial name
- NCT07040384
- Testing
- Knee Extensors Activation (KEA) Device, Conventional Towel-Based Exercise
- Volunteers
- 40 people
- Sponsor
- Jouf University
Pain, Post Operative Pain
Phase II Study of Inhaled AeroLEF for Analgesia After ACL Knee Surgery
To evaluate the safety and efficacy of self-titration to effective analgesia with inhaled AeroLEF in patients with moderate/severe acute pain in the post-surgical setting.
- Trial name
- Pain (NCT00791804)
- Testing
- AeroLEF
- Where
- 2 sites in Canada
- Volunteers
- 19 people
- Sponsor
- YM BioSciences
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Achilles Allograft With or Without InternalBrace for ACL Revision Surgery
This study evaluated outcomes after revision anterior cruciate ligament reconstruction using Achilles tendon allografts with a calcaneal bone block, with or without additional InternalBrace augmentation.
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Graft Failure, Knee Instability
- Trial name
- ACL-AlloRev (NCT07564336)
- Testing
- Revision ACL Reconstruction With Achilles Tendon Allograft and InternalBrace Augmentation, Revision ACL Reconstruction With Achilles Tendon Allograft Without InternalBrace Augmentation
- Where
- Austria
- Volunteers
- 32 people
- Sponsor
- Medical University of Graz