Clinical trials: A Randomized Controlled Trial
Chronic Neuropathic Pain
Ecstasy to Alleviate SEvere Chronic Neuropathic Pain Trial
This is a Health Canada regulated internal pilot study designed to assess the feasibility, tolerability, and preliminary efficacy of 3, 4-methylenedioxymethamphetamine hydrochloride capsules-AT for chronic neuropathic pain to…
- Trial name
- EASEPain (NCT07301632)
- Testing
- 3,4-Methylenedioxymethamphetamine, Methylphenidate
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Unity Health Toronto
Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
The goal of this clinical trial is to learn if intravenous (IV) ketamine with Dialectical Behavioural Therapy (DBT) reduces suicidal ideation in individuals with suicidality who have been diagnosed with Borderline Personality…
- Conditions
- Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder, Treatment-resistant Bipolar Depression, Major Depressive Disorder (MDD)
- Trial name
- KET-DBT (NCT07569198)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Joshua Rosenblat
Periodontitis
Evaluation of Clinical and Radiological Outcomes Following the Treatment of Periodontal Intraosseous Defects Using Autogenous Tooth-derived Graft or Autogenous Bone Graft With Enamel Matrix Derivatives. A 12-month Randomized Controlled Clinical Trial.
This clinical study aims to evaluate and compare two different materials used to treat bone defects caused by periodontitis. Periodontitis is a chronic inflammatory condition that damages the supporting structures of teeth…
- Trial name
- NCT06991998
- Testing
- Autogenous bone graft with enamel matrix derivative, Autogenous tooth-derived graft with enamel matrix derivative
- Where
- Hungary
- Volunteers
- 60 people
- Sponsor
- Semmelweis University
Menopause, Hot Flashes
Randomized Evaluation of Natural Extract for Menopausal Wellness (RENEW)
This study will evaluate whether an 8-week course of a standardized herbal extract containing Shatavari and natural bio-enhancer ingredients can reduce menopausal symptoms in post-menopausal women.
- Trial name
- RENEW (NCT07834463)
- Testing
- Shatavari (Asparagus racemosus) Extract
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- India Glycols Ltd
Fall
Effectiveness of Home-based Rehabilitation Program
This study will be an open label, simple randomized controlled trial at a single hospital. The two arms will be equally allocated on a 1:1 ratio into intervention and control groups.
- Trial name
- NCT04108793
- Testing
- Physiotherapy exercises
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Dental Restoration
Comparative Clinical Evaluation of BioFlx, Zirconia, and Stainless-Steel Crowns in Primary Molars
This study will be conducted to: Evaluate and compare the clinical success, periodontal changes, and wear of antagonist teeth for three types of prefabricated crowns in primary molars: BioFlx crowns, Zirconia crowns, and…
- Trial name
- NCT06450093
- Testing
- Preformed stainless steel crown., Preformed zirconia crown, Preformed BioFlx crown
- Where
- Egypt
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Benign Prostatic Hyperplasia (BPH)
A Phase II Clinical Trial to Evaluate the Efficacy and Safety of GV1001 in Patients With BPH
This clinical trial is designed as a randomized, placebo-controlled, single-blind, parallel design, multi-center, phase 2 clinical trial to evaluate the efficacy and safety of GV1001 in patients with benign prostatic hyperplasia.
- Trial name
- NCT02855892
- Testing
- GV1001
- Where
- 8 sites in South Korea
- Volunteers
- 161 people
- Sponsor
- GemVax & Kael
Autism, Suicide Prevention
Crisis Interventions for Pediatric Providers - Autism Version
The goal of this clinical trial is to examine the initial feasibility, acceptability, and effectiveness of Crisis Interventions for Pediatric Providers - Autism version (CIPP-A) for providers serving autistic youth in outpatient…
- Trial name
- NCT07508436
- Testing
- Safety Planning Intervention, Crisis Interventions for Pediatric Providers - Autism version (CIPP-A)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Aspiration Pneumonia
Early Stop(Ruling) of the Antibiotic Treatment During Pneumopathies d' Inhalation
The two most common consequences resulting from aspiration are chemical pneumonitis and bacterial aspiration pneumonia. Both entities present with comparable clinical signs and symptoms.
- Trial name
- APAPI (NCT03763799)
- Testing
- PCR-based microbiological diagnosis strategy, Standard microbiological diagnosis strategy
- Where
- 2 sites in France
- Volunteers
- 266 people
- Sponsor
- University Hospital, Lille
Myocardial Infarction
Impact on Physical Activity of Coronary Patients in Phase 3 of a Therapeutic Consolidation Educational Program Involving a "Patient Partner" Associated With a Healthcare Professional.
Following myocardial infarction, cardiac rehabilitation has undeniable benefits on criteria such as cardiovascular mortality and coronary recurrence. Cardiac rehabilitation consists of 3 phases: 1.
- Trial name
- P-HEARTNER (NCT05927363)
- Testing
- Therapeutic educational consolidation program in Phase 3 of cardiac rehabilitation associating a patient & caregiver partnership, Teleconsultation at 2 months, Teleconsultation at 4 months
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Refractory Carpal Tunnel Syndrome, Neurpathic Pain
Short and Long Term Exposure to Unique, Time-Varying Pulsed Electro-Magnetic Fields in Refractory Carpal Tunnel Syndrome
Pulsed electromagnetic fields (PEMF) have been approved by FDA and are utilized currently in treating non-union fractures, neurogenic bladder and musculoskeletal pains.
- Conditions
- Refractory Carpal Tunnel Syndrome, Neurpathic Pain, Neuromodulaton
- Trial name
- NCT00277563
- Testing
- reduction of pain scores by magnetic energy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weintraub, Michael I., MD, FACP, FAAN
Immune
Beverage for Immune Support
Evaluate the effects of a beverage supplement on immune health over an 8 week intervention using either a placebo or active supplement.
- Trial name
- NCT05566314
- Testing
- Amunizer
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Adenomatous Polyp of Colon
The Utility of Time Segmental Withdrawal During Screening Colonoscopy for Increasing Adenoma Detection Rate.
Colonoscopy( examining the colon with a flexible tube and a camera ) is usually done for screening purposes to find any precancerous lesions (polyps) at an early stage.
- Trial name
- NCT02538406
- Testing
- Segmental withdrawal
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Baylor College of Medicine
Gastrointestinal Disease
The Treatment of Acute Gastrointestinal Injury Via Ultrasound-guided Erector Spinae Plane Block
In this single-center, randomized, parallel control clinical trial, patients will be randomly assigned to two groups. The treatment group receives ultrasound-guided erector spinae plane block with routine treatment of Acute…
- Trial name
- NCT04934904
- Testing
- Ropivacaine injection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhujiang Hospital
Pain
Effect of Shotblocker and Palm Stimulator
This study discusses the advancements in nursing, particularly focusing on intramuscular injections, their complications, and innovative non-pharmacological methods such as the Shotblocker and palm stimulator to reduce pain.
- Trial name
- NCT06381804
- Testing
- shotblocker, palm stimulator
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Ischemic Stroke, Acute, Ischemic Stroke
A Dose-Response Controlled Trial of Bevifibatide for Acute Ischemic Stroke
BCAIS-I is a single-center, randomized, double-blind, dose-response controlled clinical Trial, to preliminarily explore the efficacy of two different maintenance doses of bevifibatide citrate injection in improving 90-day…
- Conditions
- Ischemic Stroke, Acute, Ischemic Stroke, Cerebral Infarction, Brain Diseases
- Trial name
- BCAIS-I (NCT06712004)
- Testing
- Bevifibatide citrate injection
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhujiang Hospital
Depression
Screening and Treatment of Depression in the Community
To evaluate the effectiveness of a community-based strategy of routine population mass screening for depression with follow-up feedback and management in a primary care non-psychiatric setting involving a structured…
- Trial name
- NCT00430404
- Testing
- Collaborative care (Intervention)
- Where
- Singapore
- Volunteers
- 214 people
- Sponsor
- National University Hospital, Singapore
GIT Function, Cholecystectomy, Laparoscopic
Dexamethasone, Dexmedetomidine and Their Combination on Post op. GIT Function Measured by I-FFED Score Post Laparoscopic Cholecystectomy
The goal of this clinical trial is to learn the effect of Dexamethasone and Dexmedetomidine and Their Combination on Post op. GIT Function Measured by I-FFED Score Post Laparoscopic Cholecystectomy What medical problems do…
- Conditions
- GIT Function, Cholecystectomy, Laparoscopic, Dexamethasone, Dexmedetomidine
- Trial name
- vomiting (NCT07329933)
- Testing
- Dexamethasone, Dexmedetomidine, Dexamethasone and dexmedetomidine
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Benha University
Family Caregiver
Circle Dance for Family Caregivers of the Elderly With Alzheimer.
The primary objective of this research is to compare the effects of a 12-week CircleCare on physical functioning of family caregivers of the elderly with AD.
- Trial name
- CircleCare (NCT03081533)
- Testing
- Circle Dance Program (CircleCare)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Congenital Heart Disease
Impact of a Cardiac and Mental Health Rehab Program on Well-Being and Fitness in Young Adults With Fontan Circulation: A Randomized Trial
Helping Young Adults With Fontan Circulation Feel Better and Stay Active What is the study about? This study looked at how a special program could help young adults with Fontan circulation feel better mentally and physically.
- Trial name
- (NCTXXXXXXXX) (NCT06844149)
- Testing
- CPR; (Cardiac and Psychosocial Rehabilitation) with Cardiac Rehabilitation, CR; Home-Based Cardiac Rehabilitation, Usual Care
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Samsung Medical Center