Clinical trials: A Randomized Controlled Trial
Parkinson Disease
Effect of Training and Use of Cane on Gait in Individuals With Parkinson's Disease
Introduction: Although individuals with Parkinson's disease (PD) commonly use assistive devices, the effects of these devices on gait remain poorly understood.
- Trial name
- NCT06950255
- Testing
- Cane, static stretching and health education
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- Federal University of Minas Gerais
Obesity, Childhood
Effects of Auricular Acupressure Versus Intermittent Dietary Restriction in Children With Gastric Heat and Dampness Obstruction
This is a three-month randomized controlled trial to investigate the effects of auricular acupressure versus Intermittent carbohydrate restriction on cardiometabolic risk in obese children with gastric heat and dampness…
- Trial name
- NCT05847478
- Testing
- Auricular acupressure of traditional Chinese Medicine, Intermittent low carbohydrate diet, Health education
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Children's Hospital of Fudan University
Lung Cancer, Surgery
VATS VS. Open Thoracic Surgery for Stage II - III Lung Cancer
For patients with stage I lung cancer, the NCCN guidelines point out that if the patient has no contraindications for anatomy and surgery, as long as it does not violate the standard of tumor treatment and the principle of…
- Trial name
- VOLCANO (NCT04009915)
- Testing
- VATS, Open surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Recession, Gingival
Clinical Evaluation of Laterally Closed Tunnel Technique Versus Coronally Advanced Flap Combined With Connective Tissue Graft for the Treatment of Isolated RT2 Gingival Recession
The aim of this study is to evaluate reduction of recession depth using lateral closed tunnel technique versus CAF technique using connective tissue graft in single RT2 gingival recession cases.
- Trial name
- NCT05823415
- Testing
- Laterally Closed Tunnel with CTG, CAF with CTG
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Type 2 Diabetes
Efficacy and Safety of iGlarLixi Versus Standard of Care in a Real-world Adult China Population With Uncontrolled Type 2 Diabetes on Oral Agents
This study is a prospective, open-label, multicenter, parallel-group, positive-controlled, and pragmatic randomized clinical trial (pRCT).
- Trial name
- NCT07307235
- Testing
- iGlarLixi (insulin glargine/lixisenatide), standard of care (basal insulin or premixed insulin, excluding any GLP-1 receptor agonist-containing drugs)
- Where
- 24 sites in China
- Volunteers
- 1,316 people
- Sponsor
- Shanghai Zhongshan Hospital
Major Depressive Disorder
Non-Inferiority RCT Comparing Online and On-Site CBT in MDDi
In recent years, Cognitive Behavioral Therapy has been integrated with mindfulness meditation (CBT-M) following evidence for increased efficacy when modalities are combined.
- Trial name
- NCT04825535
- Testing
- Standard psychiatry and cognitive behavioral online intervention, Standard psychiatry and cognitive behavioural in-person intervention
- Where
- Canada
- Sponsor
- Centre for Addiction and Mental Health
Diarrhea, Antibiotic Associated Diarrhea
Lactobacillus Reuteri DSM 17938 in the Prevention of Antibiotic-associated Diarrhea in Children: Protocol of a Randomized Controlled Trial
The aim of this study is to assess the effect of Lactobacillus reuteri DSM 17938 administration for the prevention of diarrhea and AAD in children.
- Trial name
- NCT02871908
- Testing
- Lactobacillus reuteri DSM 17938
- Where
- Poland
- Volunteers
- 250 people
- Sponsor
- Medical University of Warsaw
Osteoarthritis, Rheumatoid Arthritis
Reciprocating Medical Devices - a Study of a New Safety Device
The study design is a randomized study to directly compare the performance and the outcome of syringe and needle procedures with a standard syringe or the new reciprocating procedure device (RDP), which is a type of safety…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Trauma, Thyroid Nodule
- Trial name
- RPD (NCT00651625)
- Testing
- Reciprocating Procedure Device (RPD) - AVANCA Re No. 1091001, conventional syringe - BD Ref 309604
- Where
- United States
- Volunteers
- 437 people
- Sponsor
- University of New Mexico
Osteoarthritis, Knee
Effects of Digital-based Physical Activity Intervention in Individuals With Knee Osteoarthritis
Physical activity is recommended in the guidelines to improve pain and function in the treatment of knee OA, regardless of the severity of the disease, but still, patients rarely do enough physical activity.
- Trial name
- NCT05810376
- Testing
- Digital-based physical activity intervention, Patient education and exercise
- Volunteers
- 70 people
- Sponsor
- Trakya University
Pregnancy, Ceasarian Section, Anaesthesia
Transversus Abdominis Plane Block Versus Spinal Morphine After Caesarean Section : A Comparison Study
Many counties in sub-Saharan Africa have very limited post-operative nursing capacity, and relatively little data have been published about post-operative maternal pain control in these settings.
- Trial name
- NCT03263689
- Testing
- Intrathecal morphine
- Volunteers
- 130 people
- Sponsor
- Mbarara University of Science and Technology
Heart; Surgery, Heart, Functional Disturbance as Result
Clinical Impact of Del Nido Cardioplegia in Adult Cardiac Surgery
Cardioplegia solutions have been used for myocardial protection in cardiac surgery for decades. Different cardioplegic strategies have been evaluated.
- Trial name
- NCT04094168
- Testing
- DEL NIDO CARDIOPLEGIA, COLD BLOOD BASED CARDIOPLEGIA
- Where
- Spain
- Volunteers
- 474 people
- Sponsor
- JESSICA GARCIA SUAREZ
Hand Injuries, Tendon Injuries
Randomized Trial of Active vs Passive Splinting for Extensor Tendon Injuries in Zones IV to VI
This study compares two methods of post-operative immobilization after surgical repair (tenorrhaphy) of extensor tendons in the fingers.
- Trial name
- NCT06950268
- Testing
- ICAMS Splinting Protocol, Classic Plaster Immobilization
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Eating Disorder Symptom, Eating Behavior
Intuitive Eating for Disordered Eating
Purpose: Research on intuitive eating is growing, but there are few interventions demonstrating the effect of learning to eat intuitively for people with disordered eating.
- Conditions
- Eating Disorder Symptom, Eating Behavior, Body Image, Psychological Distress
- Trial name
- IERCT (NCT05031611)
- Testing
- Intuitive Eating Treatment
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Yeshiva University
Intramedullary Nail, Plate Fixation
Plating Versus Nailing in Pediatric BB Forearm Fractures
A randomized controlled trial to compare between dual intramedullary nailing and dual plating trying to synthesis a high quality evidence study that can solve the conflict between the decisions.
- Conditions
- Intramedullary Nail, Plate Fixation, Forearm Fracture, Randomized Controlled Trial
- Trial name
- DINDPL (NCT06542471)
- Testing
- Dual intramedullary nailing, Dual plating
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Helicobacter Pylori Infection
Esomeprazole/Vonoprazan Combined With High-dose Amoxicillin Dual Therapy for Primary Eradication of Helicobacter Pylori Infection
This study intends to collect the clinical data of patients with Helicobacter pylori infection, and to observe and count the high-dose double therapy and the traditional quadruple / triple therapy ( i.e., esomeprazole +…
- Trial name
- NCT06250634
- Testing
- esomeprazole + amoxicillin, esomeprazole + amoxicillin + clarithromycin + colloidal bismuth tartrate agent, Vonoprazan + amoxicillin
- Where
- China
- Volunteers
- 806 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Healthy Children
Outdoor Science Education and Child Well-being in Primary Schools: Protocol for a Cluster Randomized Controlled Trial on Learning, Connection to Nature, Eco-anxiety, and Stress
The goal of this randomized controlled trial is to learn if an outdoor science education intervention can improve primary school students' learning and well-being when compared to an indoor classroom-based science education…
- Trial name
- Bio-Explo (NCT07147634)
- Testing
- Outdoor science education, Indoor classroom-based science education
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Breast Neoplasms
Study of Radium-223 Dichloride Versus Placebo and Hormonal Treatment as Background Therapy in Subjects With Bone Predominant HER2 (Human Epidermal Growth Factor Receptor 2) Negative Hormone Receptor Positive Metastatic Breast Cancer
The objective of this study was to assess efficacy and safety of radium-223 dichloride in subjects with human epidermal growth factor receptor 2 negative (HER2 negative) hormone receptor positive breast cancer with bone…
- Trial name
- NCT02258464
- Testing
- Radium-223 dichloride (Xofigo, BAY88-8223), Background hormonal therapy
- Where
- 71 sites in United States, Austria and 18 more
- Volunteers
- 99 people
- Sponsor
- Bayer
Fracture Distal Radius, Children, Only
Robert Jones Bandage Versus Cast in the Treatment of Distal Radius Fracture in Children
Aim and objectives This study aimed to treat fractures of the distal end of the radius in the children with Robert Jones (RJ) bandage in comparison with a cast.
- Trial name
- NCT05521464
- Testing
- cast, Robert Jones Bandage
- Where
- Iraq
- Volunteers
- 148 people
- Sponsor
- University of Duhok
Knee Osteoarthritis, Cartilage Degeneration
Platelet Rich Plasma Injection for Knee Osteoarthritis
The research questions of this study are; 1. Is platelet rich plasma (PRP) treatment effective in knee osteoarthritis (OA)? 2. What are the indications for PRP treatment? 3.
- Trial name
- NCT04454164
- Testing
- PRP, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 324 people
- Sponsor
- Ferhat Say
Retained Products of Conception
Removal of Intrauterine Retained Products of Conception (RPOC) After Miscarriage Guided by Hysteroscopy Trial. A Randomized Controlled Trial.
Rationale: Elective immediate dilation and curettage (D\&C) for miscarriage is associated with the occurrence of intrauterine adhesions (IUA). IUAs may be associated with subsequent subfertility and premature birth.
- Trial name
- RIGHT (NCT04804332)
- Testing
- Operative hysteroscopy, Expectant management
- Where
- Belgium
- Volunteers
- 244 people
- Sponsor
- University Hospital, Ghent