Clinical trials: A Randomized Controlled Trial
Elective Surgery, High Risk
General Decolonization With Octenisan® Set Before Elective Orthopedic Surgery
The general decolonization of the human body surface by industrial antiseptic agents, before elective surgery is recommended by the World Health Organization (WHO).
- Conditions
- Elective Surgery, High Risk, Prevention of Surgical Site Infections, Randomized-controlled Trial
- Trial name
- BALGDEC (NCT05647252)
- Testing
- Whole Body and nasal decolonization with octenidin (Octenisan Set), Questionnaire for study participants immediately after the decolonization
- Where
- 2 sites in Switzerland
- Volunteers
- 1,086 people
- Sponsor
- Balgrist University Hospital
Ischemic Heart Disease, Non STEMI
Coronary Computed Tomography Versus Invasive Angiography for Non-ST Elevation Acute Coronary Syndrome
Coronary computed tomography angiography (CCTA) is a widely accepted initial diagnostic test for individuals suspected of having chronic coronary syndromes.
- Conditions
- Ischemic Heart Disease, Non STEMI, Angina Pectoris, Unstable, Coronary Disease
- Trial name
- TRACTION (NCT06101862)
- Testing
- CCTA, Conventional ICA, Team-based interventional triage
- Where
- 6 sites in Denmark
- Volunteers
- 2,300 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Mobile Health, Type 2 Diabetes
Electronic Patient Decision Support System for Patients with Type 2 Diabetes (DiaPaDeSS)
This study evaluates the effects of an electronic patient decision support system developed for the use of patients with type 2 diabetes (DiaPaDeSS) on self-management, patient activation, and metabolic parameters.
- Conditions
- Mobile Health, Type 2 Diabetes, Patient Activation, Self-Management
- Trial name
- DiaPaDeSS (NCT05902156)
- Testing
- DiaPaDeSS
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Akdeniz University
Randomized Controlled Trial, Breast Cancer
Acupuncture on Chemotherapy-induced Peripheral Neuropathy
Peripheral neuropathy is currently the second most common side effect after chemotherapy, second only to the side effects of blood toxicity.
- Conditions
- Randomized Controlled Trial, Breast Cancer, Chemotherapy-induced Peripheral Neuropathy, Acupuncture
- Trial name
- NCT03626220
- Testing
- acupuncture
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- China Medical University Hospital
Mild Cognitive Impairment, Randomized Controlled Trial
Effects of a Computerised Cognitive Stimulation Versus Stimulating Leisure Activities
The aim of the study is to evaluate, at the level of global cognition, cognitive neuroconstructs, memory, verbal fluency, ADLs, IADLs, symptoms of depression and anxiety, the effectiveness of a personalised and adapted…
- Conditions
- Mild Cognitive Impairment, Randomized Controlled Trial, Subjective Cognitive Impairment
- Trial name
- NCT06058611
- Testing
- Cognitive stimulation, Stimulating leisure activities
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Myopia, Randomized Controlled Trials
Effect of a Myopia Prediction System on Myopia Prevention and Control
The global rise in myopia, particularly among children and adolescents in China, underscores the inadequacy of current prevention strategies, indicating that conventional screening and education alone are insufficient to curb the…
- Conditions
- Myopia, Randomized Controlled Trials, Artificial Intelligence (AI)
- Trial name
- NCT06633393
- Testing
- Feedback on Predicted High Myopia Risk at Age 18 Using the Myopia Prediction System, Feedback on Ophthalmic Examinations
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Randomized Controlled Trial
Enhancing Psychiatric Nursing Skills in Auditory Hallucination Assessment Via AR/VR and Virtual OSCE
The purpose of this study is to develop and evaluate AI-based virtual reality teaching resources aimed at enhancing nursing students' competencies in assessing, communicating with, and managing patients experiencing auditory…
- Trial name
- NCT06605781
- Testing
- AR/VR technology-based training, traditional vedio and discussion group
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Randomized Controlled Trial
Effect of Virtual Reality-Based Relaxation Exercise on Postoperative Pain and Kinesiophobia After Total Knee Replacement
The aim of this study is to evaluate the effect of virtual reality-based relaxation exercise on pain and kinesiophobia in patients after total knee arthroplasty.
- Trial name
- NCT06591832
- Testing
- Exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Aksaray University
Randomized Controlled Trial, Dexmedetomidine
Effect of Dexmedetomidine on Central Nervous System Complications in Patients Undergoing Cardiac Surgery
With the continuous improvement of medical technology, more and more patients need to undergo surgery as a kind of treatment for their diseases.
- Trial name
- NCT06551259
- Testing
- Dexmedetomidine, physiological saline
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Intramedullary Nail, Plate Fixation
Plating Versus Nailing in Pediatric BB Forearm Fractures
A randomized controlled trial to compare between dual intramedullary nailing and dual plating trying to synthesis a high quality evidence study that can solve the conflict between the decisions.
- Conditions
- Intramedullary Nail, Plate Fixation, Forearm Fracture, Randomized Controlled Trial
- Trial name
- DINDPL (NCT06542471)
- Testing
- Dual intramedullary nailing, Dual plating
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Local Antibiotic Injection Catheter Acute Periprosthetic Infections Knee DAIR Randomized Controlled Trial
Efficacy of Local Antibiotic Injection Via a Catheter for Treating Acute Periprosthetic Infections After Knee DAIR Surgery
Prosthetic Joint Infection (PJI) is a severe complication following joint replacement surgery, imposing significant economic and health burdens on patients.
- Trial name
- YES (NCT06468163)
- Testing
- Drug infusion into joint through catheter.
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Xinjiang Medical University
Nursing Education, Nursing Students
The Effect of Online Sexual Health Training Given to Nursing Students on Knowledge, Attitude and Self-Efficacy
Nurses play an important role in providing sexual health care to individuals. In this study, online sexual health training will be implemented in an innovative way by supporting the use of models in the process of providing…
- Conditions
- Nursing Education, Nursing Students, Randomized Controlled Trial, Sexual Health
- Trial name
- NCT06460935
- Testing
- sexual health training
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Marmara University
Diabete Mellitus, Aging
Buyuan-zhixiao Formula in the Treatment of Elderly Patients With Diabetes and Multiple Metabolic Disorders
The primary objective of this clinical trial is to assess the clinical efficacy and safety of the Buyuan Zhixiao Formula in treating elderly patients with diabetes and multiple metabolic disorders exhibiting symptoms of renal…
- Conditions
- Diabete Mellitus, Aging, Metabolic Disorders, Traditional Chinese Medicine
- Trial name
- NCT06358118
- Testing
- Buyuan Zhixiao Formula
- Where
- 6 sites in China
- Volunteers
- 240 people
- Sponsor
- Qing Ni
Breast Cancer, Breast Cancer Female
Conversations in Light and Shadow: Assessing Phototherapy's Impact on Breast Cancer Patients
This study examines the impact of phototherapy intervention on anxiety, stress, and body image among breast cancer patients. Participants engaged in a five-week, one-on-one session series, utilizing a pre-post-test design with…
- Conditions
- Breast Cancer, Breast Cancer Female, Randomized Controlled Trial
- Trial name
- NCT06412133
- Testing
- photography
- Where
- 2 sites in Taiwan
- Volunteers
- 57 people
- Sponsor
- Yun-Chen Chang
Pain, Ecchymosis
The Effect of Chilled Needle on the Development of Pain and Ecchymosis in Subcutaneous Injection in Adults
Subcutaneous (SC) injection applications are the process of administering the drug to the loose connective tissue under the skin and is one of the most frequently applied parenteral drug administration methods among nursing…
- Conditions
- Pain, Ecchymosis, A Randomized Controlled Trial, Subcutaneous Injections
- Trial name
- NCT06222216
- Testing
- Chilled Needle, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Randomized Controlled Trial, Prostate Cancer
Comparing Bp-MRI and Mp-MRI for Prostate Cancer Screening Accuracy
3.1 Study Objectives: 3.1.1 Primary objective: The investigators aim to address these questions for Taiwan males suspicious of csPCA, with PSA range of 4-20 ng/ml by conducting a RCT trial.
- Conditions
- Randomized Controlled Trial, Prostate Cancer, Magnetic Resonance Imaging
- Trial name
- NCT06402552
- Testing
- bp-MRI prostate, mp-MRI prostate
- Where
- Taiwan
- Volunteers
- 370 people
- Sponsor
- Chang Gung Memorial Hospital
Artificial Intelligence, Machine Learning
Appropriate Use of Blood Cultures in the Emergency Department Through Machine Learning
The goal of this clinical trial is to study whether the use of our blood culture prediction tool is non-inferior to current practice and if it can improve certain outcomes in all adult patients presenting to the emergency…
- Conditions
- Artificial Intelligence, Machine Learning, Microbiology, Emergency Service, Hospital
- Trial name
- ABC (NCT06163781)
- Testing
- Blood culture prediction tool
- Where
- Netherlands
- Volunteers
- 7,584 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Parkinson Disease, Constipation
Efficacy of Acupuncture for the Treatment of Parkinson's Disease Related Constipation
The purpose of the study is to evaluate the efficacy of acupuncture in treating Parkinson's disease related constipation (PDC). In the randomized controlled clinical trial study, patients meeting the criteria for inclusion will…
- Conditions
- Parkinson Disease, Constipation, Non-motor Symptom, Randomized Controlled Trial
- Trial name
- AFPDC (NCT06390761)
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xi'an No.3 Hospital
Randomized Controlled Trial
Cost-utility and Physiological Effects of LDN in Patients With Fibromyalgia
Background: Low-dose naltrexone (LDN) may be useful in managing the pathologies that alter inflammatory markers, such as Crohn's disease or fibromyalgia (FM).
- Trial name
- INNOVA (NCT04739995)
- Testing
- Low-dose naltrexone
- Where
- Spain
- Volunteers
- 99 people
- Sponsor
- Fundació Sant Joan de Déu
Interscalene Block, Erector Spinae Plane Block
Interscalene Block Alone Versus Interscalene Block With Erector Spinae Plane Block for Shoulder Arthroscopy Anesthesia
The aim of this study is to compare the effectiveness of interscalene brachial plexus block alone versus interscalene brachial plexus block +Erector spinae plane block in anesthesia for shoulder arthroscopy.
- Conditions
- Interscalene Block, Erector Spinae Plane Block, Shoulder Arthroscopy Anesthesia, Randomized Controlled Trial
- Trial name
- NCT05646667
- Testing
- interscalene with Erector spinae plane block group, Interscalene group
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University