Clinical trials: sponsored by Chinese University of Hong Kong
Severe Aplastic Anemia (SAA), Severe Aplastic Anemia, Refractory
Phase I Clinical Study of Haplo-HSCT Combined With Hypoxic 3D-Cultured Umbilical Cord MSC for the Treatment of SAA
Efficacy and Safety of Sequential Infusion of Hypoxic 3D-Cultured Umbilical Cord Mesenchymal Stem Cells in Haploidentical Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia: A Multicenter, Randomized, Phase 1 Trial
- Conditions
- Severe Aplastic Anemia (SAA), Severe Aplastic Anemia, Refractory, Severe Aplastic Anemia
- Trial name
- NCT07299123
- Testing
- 3D hypoxia-preconditioned UC-MSC group, 2D UC-MSC group
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Chinese PLA General Hospital
Insomnia, Anxiety
Efficacy of Group Cognitive Behavioural Therapy for Youth Anxiety and Insomnia
Youth is an important transitional stage associated with dynamic changes in biological, cognitive, and psychological functioning, as well as a constellation of developmental and psychosocial challenges.
- Trial name
- NCT06054243
- Testing
- CBT-I, CBT-A
- Where
- Hong Kong
- Volunteers
- 137 people
- Sponsor
- The University of Hong Kong
Mental Well-being, Adolescent Health
Youth-for-Youth Mental Wellness Care and Action
This initiative aims to improve flourishing and quality of life of secondary school students, reduce mental distress (e.g., depression and suicidal ideation), enhance their understanding of mental health (e.g., mental health…
- Conditions
- Mental Well-being, Adolescent Health, Mental Health Literacy, School Difficulties Associated With Mental Health Problems
- Trial name
- NCT06955195
- Testing
- School-based intervention program on improving adolescent mental wellbeing, Control-no treatment
- Where
- 2 sites in Hong Kong
- Volunteers
- 18,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Anxiety, Depression / Major Depressive Disorder
The Effectiveness of a One-stop Electronic Clinic for Psychological Service (eClinic) in Hong Kong
With an increasing need for effective and accessible mental health services, telepsychology can be one promising solution to narrowing the gap between demand and supply.
- Conditions
- Anxiety, Depression / Major Depressive Disorder, Common Mental Disorder
- Trial name
- NCT07597967
- Testing
- Internet-based Unified Protocol (UP) Intervention
- Where
- Hong Kong
- Volunteers
- 420 people
- Sponsor
- New Life Psychiatric Rehabilitation Association
Food Allergy in Children, Food Allergy Peanut
Pathway to Peanut Tolerance
While rigorous clinical trials have established peanut OIT as a promising therapy capable of inducing desensitization and even remission, its transition to routine clinical practice requires robust real-world evidence.
- Trial name
- NCT07592780
- Testing
- Peanut Oral Immunotherapy (OIT)
- Where
- Hong Kong
- Volunteers
- 125 people
- Sponsor
- Chinese University of Hong Kong
Fish Allergy, Food Allergy in Children
Fish Oral Immunotherapy in Hong Kong Children
At present there is no cure for food allergy. People with a food allergy need to avoid the food they are allergic to in order to stay safe, but we know that accidental exposure is common.
- Trial name
- NCT05590299
- Testing
- Fish oral immunotherapy (codfish)
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- Chinese University of Hong Kong
Food Allergy in Children, Food Allergy
Boiled Tree Nut for Oral Immunotherapy in Food-allergic Children
As the global prevalence of food allergy steadily increases, tree nut (TN) becomes one of the main triggers of food-allergic reactions and food anaphylaxis.
- Trial name
- NCT06467994
- Testing
- Cashew oral immunotherapy
- Where
- Hong Kong
- Volunteers
- 75 people
- Sponsor
- Chinese University of Hong Kong
Autistic Disorders Spectrum, Child Development
The Effects of a Nurse-led Community-based Sailing Programme on Resilience of School-aged Children With Autism
The goal of this pilot RCT is to evaluate the feasibility and acceptability of the community-based sailing program and to assess the preliminary effects before the main RCT, given the literature on sailing for children with ASD…
- Trial name
- NCT06575244
- Testing
- Community-based sailing, Crafting activities
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- Chinese University of Hong Kong
Stress (Psychology)
Strengthening the Parent-Child Relationship Through Urban Nature
The study uses an experimental design (RCT) to estimate the causal impact of nature-based activities on the parent-child relationship and children's emotional regulation without random assignment.
- Trial name
- NCT07570498
- Testing
- Outdoor activity
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Chinese University of Hong Kong, Shenzhen
UGI Bleed
A Prospective Pilot Study to Evaluate the Diagnostic Performance of a Wireless Sensor Capsule in Detection of UGIB
It is a single-center, prospective study, which will be conducted in a tertiary academic hospital (Prince of Wales Hospital). All subjects will undergo a paired examination of HemoPill® acute capsule and…
- Trial name
- HemoPill (NCT06409182)
- Testing
- Hemopill
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Depressive Symptoms, Anxiety
School-based Group Acceptance and Commitment Therapy for Adolescents
The objective of the investigators' mental health promotion intervention premised on the Acceptance and Commitment Therapy (ACT) framework in secondary school settings aims to enhance young people's psychological flexibility and…
- Conditions
- Depressive Symptoms, Anxiety, Stress
- Trial name
- NCT06039228
- Testing
- Acceptance and commitment therapy
- Where
- Hong Kong
- Volunteers
- 61 people
- Sponsor
- Chinese University of Hong Kong
Nurse Training
Integrating Design Thinking Into Undergraduate Nursing Education
Previous studies have demonstrated that design thinking workshops can indeed produce these effects in healthcare education settings. However, its effectiveness in nursing curriculum is inconclusive.
- Trial name
- NCT06673316
- Testing
- Design thinking workshop
- Where
- Hong Kong
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Gastric Cancer (Diagnosis), Gastrectomy
The UGIRA International Registry for RAMIG for Gastric Cancer
Minimally invasive gastrectomy (MIG) has gained in popularity, since it is feasible, safe and oncologically comparable to open gastrectomy, while morbidity and duration of hospitalization are reduced, quality of life is…
- Trial name
- NCT07517432
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Epilepsies, Partial
High-resolution Multi-parametric Magnetic Resonance Imaging for Focal Epilepsy
Patients with focal epilepsy often have diagnostic difficulties as their culprit for seizures are difficult to be picked up using conventional imaging.
- Trial name
- NCT06550726
- Testing
- Magnetic Resonance Imaging
- Where
- Hong Kong
- Volunteers
- 66 people
- Sponsor
- Chinese University of Hong Kong
Autism Spectrum Disorder, Anxiety
Open-label Pilot Study Synbiotic Treatment for Autism Spectrum Disorder
The objective of this study is to conduct a open-label pilot study evaluating the feasibility, tolerability and preliminary efficacy of a 12-week course of synbiotic in improving anxiety symptoms in children with ASD.
- Trial name
- NCT06126185
- Testing
- 12-week course of synbiotic
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Scoliosis, Spinal Curvatures
Using Radiation-free Ultrasound for Screening Scoliosis Among Female School Children in Hong Kong to Reduce Unnecessary X-ray Exposure
In the scoliosis screening program of the Student Health Service (SHS), Department of Health (DH), in Hong Kong, more than 50% of screened school children prescribed with x-ray examination basing on the screening protocol did not…
- Conditions
- Scoliosis, Spinal Curvatures, Spinal Diseases, Bone Diseases
- Trial name
- SScoE (NCT06828068)
- Testing
- Ultrasound (Scolioscan system), and EOS radiography system
- Where
- Hong Kong
- Volunteers
- 442 people
- Sponsor
- Chinese University of Hong Kong
Mental Distress
Narrative Therapy Among Young People With Moderate Level of Mental Distress in Hong Kong
This cluster randomized controlled trial (cRCT) aims to evaluate the effectiveness of a narrative therapy (NT) intervention in (i) reducing mental distress, depressive symptoms, and anxiety, as well as (ii) enhancing perceived…
- Trial name
- NCT07231406
- Testing
- Narrative Therapy
- Where
- Hong Kong
- Volunteers
- 770 people
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder, Parent-Child Relations
RCT of a Mobile Phone App-based Intervention for Parents of Children With Autism Spectrum Disorder (ASD)
The objective of this study is to evaluate the effectiveness of a 6-week mobile app-based intervention in empowering and supporting Chinese parents of ASD children through knowledge and skills transfer and mindfulness training…
- Trial name
- NCT05927116
- Testing
- Mobile phone app-based intervention for supporting and empowering parents of children with autism spectrum disorder (ASD)
- Where
- Hong Kong
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Disability, Adolescent Learning, Psychosocial Problem
Effects of a Laughter Yoga Program in Adolescents With Disabilities
A pilot randomized controlled trial will be adopted. A total of forty adolescents with intellectual and physical disabilities will be randomly allocated into either intervention group receiving a 4-week laughter yoga programme (8…
- Trial name
- NCT05832346
- Testing
- Laughter yoga programme
- Where
- Hong Kong
- Volunteers
- 45 people
- Sponsor
- Chinese University of Hong Kong
Mental Well-being, Mental Health Issue
Randomized Controlled Trial on Precision Mental Health
The current study aims to evaluate the effectiveness of different online psychological interventions, including guided and unguided transdiagnostic cognitive behavioural therapy, and unguided mindfulness-based intervention, on…
- Conditions
- Mental Well-being, Mental Health Issue, Mental Health Wellness 1, Precision Mental Health
- Trial name
- NCT05825040
- Testing
- Online guided transdiagnostic cognitive behavioural therapy, Online self-guided transdiagnostic cognitive behavioural therapy, Online self-guided mindfulness-based intervention
- Where
- Hong Kong
- Volunteers
- 320 people
- Sponsor
- Chinese University of Hong Kong