Find a clinical trial
Congenital Heart Disease (CHD)
Autologous Thymus Transplant in Children With Congenital Heart Disease: A Pilot Study
This pilot study will look at whether putting back a child's own thymus tissue during heart surgery is safe and may help support the immune system in children with congenital heart disease (CHD).
- Trial name
- ATTT (NCT07799259)
- Testing
- Autologous Thymus Transplant
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cerebral Palsy
Sensory Integration Therapy vs Conventional Physical Therapy in Children With Mixed Cerebral Palsy
The study aims to compare Sensory Integration Therapy (SIT) with Conventional Physical Therapy (CPT) for improving gross motor function in children aged 4-10 years with mixed cerebral palsy.
- Trial name
- NCT07921069
- Testing
- Sensory Integration Therapy, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Foreign Body Ingestion
Foreign Body Ingestion During COVID-19 Lockdown
Ingestion of foreign bodies (FB) is one of the most observed domestic accidents and a frequent reason for consultation in pediatric emergency departments (PED).
- Trial name
- COCE (NCT05261074)
- Testing
- No intervention
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Respiratory Distress Syndrome
Development and Multicenter Validation of an Explainable System for Neonatal ARDS-Compatible Phenotyping
Neonatal acute respiratory distress syndrome (NARDS) can be difficult to identify consistently because relevant information is distributed across clinical notes, imaging reports, and respiratory support records.
- Trial name
- NCT07920718
- Volunteers
- 1,600 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Diabetes Mellitus, Type 2
Prospective Studies of the Natural History of Diabetes Mellitus and Its Complications in the Gila River Indian Community
This project is a continuation of an extensive longitudinal population-based epidemiological investigation of the etiology and determinants of type 2 diabetes (and its complications) and formerly arthritis.
- Trial name
- NCT00339482
- Where
- United States
- Volunteers
- 12,647 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Schizophrenia, Autism-Related Irritability
A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents
The purpose of this study is to evaluate the long-term safety and tolerability of Xanomeline and Trospium Chloride for the treatment of psychiatric disorders in children and adolescents
- Trial name
- NCT07424404
- Testing
- KarXT, KarX-EC
- Where
- 105 sites in United States, Australia and 9 more
- Volunteers
- 400 people
- Sponsor
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Pediatric Acute Respiratory Failure
Regional Lung Ventilation During Prone Position in in Intubated Children
Mechanical ventilation can lead to pulmonary, diaphragmatic, and hemodynamic complications due to an increase in global and regional transpulmonary pressure.
- Trial name
- ChildProne-EIT (NCT07921745)
- Testing
- Thoracic electric impedance tomography to assed regional ventilation, Positive end-expiratory pressure (PEEP) trial titration, Collection of clinical Data
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anomalies Chromosome
The Contribution of Optical Mapping to the Characterization of Chromosomal Rearrangements in Patients With Neurodevelopmental Disorders
In neurodevelomental disorders, duplications are genomic variations that are difficult to interpret because their orientation cannot be defined by conventional techniques (ACPA and FISH).
- Trial name
- Bionano (NCT07133789)
- Testing
- blood sampling of all patients and their parents
- Where
- France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Reading Difficulties, Behavioral Problems
Study of Psychoeducation and Reading for Kids (SPARK)
The Study of Psychoeducation and Reading for Kids (SPARK) is a trial of a broad-spectrum psychoeducational tutoring intervention.
- Conditions
- Reading Difficulties, Behavioral Problems, Emotional Problems
- Trial name
- SPARK (NCT07922876)
- Testing
- Psychoeducational tutoring
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- State University of New York - Upstate Medical University
Low Grade Astrocytoma, Low Grade Glioma
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma
This phase III trial compares the effect of selumetinib versus the standard of care treatment with carboplatin and vincristine (CV) in treating patients with newly diagnosed or previously untreated low-grade glioma (LGG) that…
- Conditions
- Low Grade Astrocytoma, Low Grade Glioma, Metastatic Low Grade Astrocytoma, Metastatic Low Grade Glioma
- Trial name
- NCT04166409
- Testing
- Biospecimen Collection, Carboplatin, Echocardiography Test
- Where
- 132 sites in United States, Canada and 1 more
- Volunteers
- 170 people
- Sponsor
- National Cancer Institute (NCI)
Ondine Syndrome (Congenital Central Hypoventilation Syndrome)
Locus Coeruleus and CCHS (Congenital Central Hypoventilation Syndrome)
This study investigates whether cognitive dysfunction in young patients with congenital central hypoventilation syndrome (Ondine Syndrome) is related to the severity of the disease and dysfunction of the locus coeruleus (a…
- Trial name
- ONDINE-LC (NCT07081464)
- Testing
- MRI, EEG, Pupillometry
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myelodysplastic Syndromes
Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms
Background: Myelodysplastic syndrome (MDS) and myelodysplastic/myeloproliferative neoplasm (MDS/MPN) are blood disorders that can cause serious complications in children and adults.
- Trial name
- NCT06303193
- Testing
- pacritinib
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- National Cancer Institute (NCI)
Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8
Decision Aid for the Improvement of Decision-Making in Patients With Non-small Cell Lung Cancer
This clinical trial refines and tests the effect of a decision aid in improving decision-making in patients with non-small cell lung cancer.
- Conditions
- Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8
- Trial name
- NCT04946279
- Testing
- Best Practice, Informational Intervention, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 98 people
- Sponsor
- OHSU Knight Cancer Institute
Attention Deficit Hyperactivity Disorder (ADHD)
Micronutrient Supplementation and Chronotherapy in Children With ADHD
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition in children that can affect attention, behavior, learning, and daily functioning.
- Trial name
- SMART-ADHD (NCT07922252)
- Testing
- Broad-spectrum multivitamin and mineral supplementation, Chronotherapy-Based Lifestyle Guidance
- Where
- Malaysia
- Volunteers
- 120 people
- Sponsor
- UCSI University
Stereotypical Prolonged Seizures
A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
The purpose of the study is to assess the success of a single administration of Staccato alprazolam compared with placebo both in rapidly terminating a seizure episode within 90 seconds and with no recurrence of seizure(s) up to…
- Trial name
- NCT05077904
- Testing
- Staccato alprazolam
- Where
- 183 sites in United States, Australia and 11 more
- Volunteers
- 350 people
- Sponsor
- UCB Biopharma SRL
Autism Spectrum Disorder
Sensory-integration Therapy Verses Augumented Reality-based Training in ASD
To determine and contrast the effects of Sensory Integration Therapy (SIT) and Augmented Reality-Based Training (AR) on gross motor skills, assessed using the Test of Gross Motor Development-Third Edition (TGMD-3), in children…
- Trial name
- NCT07921199
- Testing
- Augumented Reality-Based Training, Sensory-Integration Therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Pre-myopia, Myopia
Managing Premyopia in Chinese Children Using Artificial Intelligence Assisted Defocus Incorporated Multiple Segments Based Spectacle Lens: a Randomized Controlled Clinical Trial
Pre-myopia refers to a condition in which children have not yet developed myopia but exhibit insufficient hyperopic reserve (≤ +0.75 D).
- Trial name
- NCT07765550
- Testing
- Artificial Intelligence Assisted DIMS based Spectacle Lens, Smartwatches
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
ADHD
Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol (FOCUS-2)
This study is a Phase 3, multi-center, randomized, 6-week, double-blind, placebo-controlled, parallel-group trial to assess the efficacy and safety of solriamfetol in children aged 6 to <12 years with ADHD.
- Trial name
- NCT07717879
- Testing
- Solriamfetol Dose A, Solriamfetol Dose B
- Where
- 32 sites in United States
- Volunteers
- 468 people
- Sponsor
- Axsome Therapeutics, Inc.
Pediatric Cancer
Psychological Benefits of a Normalized Camping Experience for Children With Cancer
Background: Cancer has an enormous impact on the psychological and social well-being of the family unit. The life-threatening connotations of cancer single out the ill child from his peer/family group as one who is different, and…
- Trial name
- NCT00001186
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- National Cancer Institute (NCI)
Anorexia Nervosa
Body Composition in Adolescents With Anorexia Nervosa
Body Mass Index (BMI) is currently the most widely recommended parameter for identifying underweight subjects. Among eating disorder diseases, anorexia nervosa (AN) is the one with the highest mortality rate and with relapses…
- Trial name
- COCOMETANNER (NCT06800742)
- Testing
- Collection of anthropometric and biochemical parameters
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Istituto Auxologico Italiano
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.