Clinical trials: sponsored by Samsung Medical Center
Gallbladder Cancer
Artificial Intelligence-based Tumor Microenvironment Analysis for Prognosis Prediction in Gallbladder Cancer
This retrospective study aims to investigate the prognostic significance of artificial intelligence (AI)-powered analysis of tumor-infiltrating lymphocytes (TILs) and the tumor microenvironment (TME) in patients with resected…
- Trial name
- NCT07092397
- Where
- South Korea
- Volunteers
- 266 people
- Sponsor
- Samsung Medical Center
Diabetes (DM), Physical Activity
Effect of Regular Physical Activity in Normal-Weight Individuals With Type 2 Diabetes and Abdominal Obesity
Individuals with T2DM accompanied by abdominal obesity tend to experience worse clinical outcomes. To identify modifiable factors that may improve these outcomes, the investigators conducted a retrospective cohort study using…
- Trial name
- PA-NormalWtDM (NCT07071545)
- Testing
- Regular physical activity, No regular physical activity
- Volunteers
- 249,247 people
- Sponsor
- Samsung Medical Center
Disabilities, Type 2 Diabetes
The Impact of Medication Adherence in Patients With Type 2 Diabetes and Disabilities
Individuals with disabilities and type 2 diabetes tend to have worse clinical outcomes. To identify modifiable factors that may improve these outcomes, the investigators evaluated the role of medication adherence.
- Trial name
- NCT07052708
- Testing
- No adherence group, Adherence group
- Volunteers
- 365,295 people
- Sponsor
- Samsung Medical Center
Neuromyelitis Optica Spectrum Disorder (NMOSD)
Efficacy and Safety of Conventional Immunosuppressant Therapies in Elderly Patients With Neuromyelitis Optica Spectrum Disorder
Newly diagnosed NMOSD patients
- Trial name
- NCT07032337
- Volunteers
- 2,985 people
- Sponsor
- Samsung Medical Center
Gastric Cancer Stage IV
Conversion Surgery After Target Therapy or Immunotherapy in Stage IV Gastric Cancer
In this retrospective study, investigators conducted a comprehensive investigation of the factors influencing postoperative prognosis in patients with stage IV gastric cancer undergoing conversion surgery.
- Trial name
- NCT07009600
- Testing
- immune check point inhibitors (PD-1 inhibitors), target therapy (trastuzumab)
- Volunteers
- 124 people
- Sponsor
- Samsung Medical Center
Cerebral Palsy, Spastic Hemiplegic
Effects of Constraint-induced Movement Therapy With Home-based Hand-arm Bimanual Intensive Therapy in Children With Unilateral Cerebral Palsy
This study evaluates the therapeutic effects of constraint-induced movement therapy (CIMT) with home-based hand-arm bimanual intensive therapy (H-HABIT) with unilateral cerebral palsy.
- Trial name
- NCT04904796
- Testing
- CIMT, H-HABIT
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Samsung Medical Center
Cell Transplantation
Efficacy and Safety of Pneumostem® for IVH in Premature Infants (Phase 2a)
The objective of this study is to evaluate the efficacy and safety of a single intraventricular administration of Pneumostem® for treatment of Intraventricular hemorrhage (IVH) in high-risk premature infants by comparing…
- Trial name
- NCT02890953
- Testing
- Pneumostem, Normal saline
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Samsung Medical Center
Intraoperative Hypotension, General Anesthesia
Deep Learning Models for Prediction of Intraoperative Hypotension Using Non-invasive Parameters
The investigators aimed to investigate the deep learning model to predict intraoperative hypotension using non-invasive monitoring parameters.
- Trial name
- NCT05762237
- Where
- South Korea
- Volunteers
- 5,175 people
- Sponsor
- Samsung Medical Center
Acute Myocardial Infarction, Cancer
Acute Myocardial Infarction in Cancer Patients
Using national health insurance service database, current study aim to evaluate the risk and prognosis of acute myocardial infarction in cancer patients and to find the optimal treatment strategy for acute myocardial infarction…
- Trial name
- NCT06281054
- Testing
- Revascularization
- Where
- South Korea
- Volunteers
- 4,500,000 people
- Sponsor
- Samsung Medical Center
Acute Coronary Syndrome, Ischemic Heart Disease
PreDiction and Validation of Clinical CoursE of Coronary Artery DiSease With CT-Derived Non-Invasive HemodYnamic Phenotyping and Plaque Characterization (DESTINY Study)
Acute coronary syndrome (ACS) and sudden cardiac death can be the first manifestation of coronary artery disease and are the leading cause of death in the majority of the world's population.
- Trial name
- DESTINY (NCT04794868)
- Testing
- CCTA-derived high risk plaque characteristics, CFD-derived hemodynamic parameters
- Where
- 2 sites in China, South Korea
- Volunteers
- 356 people
- Sponsor
- Samsung Medical Center
ST-segment Elevation Myocardial Infarction (STEMI)
Angio-IMR and Cardiac MR-derived MVO in STEMI Patients
Coronary microcirculatory dysfunction has been known to be prevalent even after successful revascularization of ST-segment elevation myocardial infarction (STEMI) patients.
- Trial name
- NCT04828681
- Testing
- Cardiac magnetic resonance imaging
- Where
- 2 sites in United States, China
- Volunteers
- 324 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease, Coronary Artery Stenosis
Nationwide Cohort Study of Antiplatelet Agents as Primary Prevention
There is no specific recommendation regarding pharmacologic treatment as primary prevention for patients with intermediate coronary artery stenosis whose revascularization was deferred based on negative fractional flow reserve…
- Trial name
- NHIS (NCT06281041)
- Testing
- Antiplatelet Agents
- Where
- South Korea
- Volunteers
- 4,657 people
- Sponsor
- Samsung Medical Center
Ischemic Heart Disease, Microvascular Coronary Artery Disease
Prognostic Impact of Cardiac Diastolic Function and Coronary Microvascular Function
The DIAST-CMD registry (Prognostic Impact of Cardiac Diastolic Function and Coronary Microvascular Function) is prospective registry which enrolled patients who underwent echocardiography, cnically-indicated invasive coronary…
- Conditions
- Ischemic Heart Disease, Microvascular Coronary Artery Disease, Diastolic Dysfunction, Heart Failure With Preserved Ejection Fraction
- Trial name
- DIAST-CMD (NCT05058833)
- Testing
- Echocardiography, Coronary flow reserve and index of microcirculatory dysfunction
- Where
- 4 sites in United States, South Korea
- Volunteers
- 800 people
- Sponsor
- Samsung Medical Center
Pediatric Cancer, Psychology, Child
Usability and Utility of Mindfulness-based Life Management Social Robots for Children and Adolescents in the Long-term Treatment
The purpose of this study is to apply social robot-based mindfulness-based life management content to pediatric and adolescent patients in the long-term disease treatment process and to assess usability and effectiveness of the…
- Trial name
- NCT06763042
- Testing
- Mindfulness-based Life Management Social Robots
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Nursing, Education
Utilizing of Augmented Reality Technology Education Program for Nurse
It is important to provide practice-oriented education for nurses in a safe environment. As it became difficult to maintain face-to-face education and practice environment due to COVID-19, a new paradigm for nurse education was…
- Trial name
- NCT05629663
- Testing
- AR guidance with Hololens 2
- Where
- South Korea
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Haploidentical Hematopoietic Stem Cell Transplantation
Haploidentical Hematopoietic Stem Cell Transplantation With Early ATG and Low Dose Post-transplant Cyclophosphamide
Aim of this study is to investigate the effect of early administration of anti-thymocyte globulin and post-transplant low-dose cyclophosphamide in heploidentical hematopoietic stem cell transplantation.
- Trial name
- NCT06041893
- Testing
- ATG-LDPTCy
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Neoplasm
The Samsung Medical Center Comprehensive Cancer Center Registry from 2008 to 2023
This is a retrospective cohort study using the Samsung Medical Center Cancer Registry, including cancer patients between 2008 and 2022. To monitor trends in patient demographics, treatment patterns, and outcomes.
- Trial name
- SCCCR08-23 (NCT06703957)
- Where
- South Korea
- Volunteers
- 301,055 people
- Sponsor
- Samsung Medical Center
Epilepsy
A Study on Telemedicine Applied to Actual Outpatient Clinic for Epilepsy
This is an observational study to confirm the non-inferior effectiveness on health outcomes of tele-counseling or tele-prescription, which was the first outpatient system applied to the actual medical sites in Korea during the…
- Trial name
- NCT05418257
- Testing
- (exposure) telemedicine
- Where
- South Korea
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Pain, Chronic
Usability Evaluation of a Mindfulness-based Serious Game
The purpose of this study is to evaluate the usability of a mindfulness-based serious game developed for pediatric and adolescent patients who require pain management during their disease treatment.
- Trial name
- NCT06522425
- Testing
- mindfulness-based serious games
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- Samsung Medical Center
Equipment and Supplies, Augmented Reality
Effects of Augmented Reality-based Rapid Blood Transfusion (Level-1®)
The goal of this clinical trial is to compare the effectiveness of AR-based training with traditional guideline-based self-learning in practical nurses without prior Level-1® experience.
- Conditions
- Equipment and Supplies, Augmented Reality, Nurse's Role
- Trial name
- NCT06506851
- Testing
- AR-based Training with Microsoft HoloLens 2®, Traditional Guideline-based Self-Learning
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Samsung Medical Center