Clinical trials: Remifentanil
Anesthesia and Neurotoxicity
Association Between Anesthetic Drugs for General Anesthesia and Postoperative Intelligence/behavioral Assessment Results in Children
In this study, we compared the results of the intelligence and behavioral test performed after surgery between the group using sevoflurane and the group receiving dexmedetomidine and remifentanil, in Korean children under 2 years…
- Trial name
- NCT04364945
- Testing
- dexmedetomidine, remifentanil, Sevoflurane
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Seoul National University Hospital
Opioid Use
Pupillometry-guided Remifentanil Infusion Versus Conventional Administration in Children
Our study aims to compare the total intravenous dose of remifentanil per anesthesia hour and body weight in two groups of pediatric surgical patients - an interventional group with remifentanil infusion under pupillometry…
- Trial name
- PURFT (NCT03749811)
- Testing
- Pupillometry
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Idiopathic Scoliosis
Methadone vs Magnesium in Spinal Fusion
Significant pain may occur following posterior spinal fusion despite the use of conventionally accepted techniques including patient controlled analgesia.
- Trial name
- NCT01795495
- Testing
- Methadone hydrochloride, Magnesium Sulfate, Remifentanil
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Nationwide Children's Hospital
Airway Complication of Anesthesia
Effects of Propofol on Respiratory Adverse Events During Extubation in Children Undergoing Tonsil Adenoidectomy
The main objective of this study was to investigate whether propofol assisted extubation could reduce the incidence of respiratory adverse events in children with tonsil adenoidectomy.
- Trial name
- NCT05769842
- Testing
- propofol, normal saline
- Where
- China
- Volunteers
- 239 people
- Sponsor
- Children's Hospital of Fudan University
Surgical Procedure, Unspecified
Nociception Level-guided Remifentanil Dosing in Children During General Anesthesia
The investigators aim to investigate whether administration of a short-acting opioid (remifentanil) guided by a pain monitor (nociceptive level monitor) during anesthesia, can reduce pain in children after surgery.
- Trial name
- NCT05725382
- Testing
- The NOL monitor (Pain Monitoring Device monitor-PMD200™)
- Where
- 4 sites in Denmark
- Volunteers
- 264 people
- Sponsor
- Pia Jaeger, MD, PhD
Anesthesia, Electroencephalography/ Drug Effect
Detection of Consciousness by EEG and Auditory Evoked Potentials
The objective of the present investigation is to analyze EEG and auditory evoked potentials at the transition from consciousness to unconsciousness and vice versa.
- Trial name
- NCT01720615
- Testing
- Propofol / Remifentanil, Sevoflurane / Remifentanil
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Technical University of Munich
Endotracheal Intubation
Optimum Dose of Remifentanil for Intubation in Small Children
The routine medications to relax the muscles of the throat are an anesthetic drug, propofol, in combination with an ultra short acting pain medicine, remifentanil.
- Trial name
- NCT00474071
- Testing
- Remifentanil
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Anesthetic Sparing
The Effects of Dexmedetomidine on Intravenous Anesthetic Requirements for Children Undergoing Dental Procedures
The investigators propose to determine the propofol and remifentanil sparing effects of a single dose of dexmedetomidine in the dental population.
- Trial name
- Dexmed-PRS (NCT03422978)
- Testing
- Dexmedetomidine, Normal saline
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- University of British Columbia
Anesthesia, General
Use of Bispectral Index (BIS) for Monitoring of Total Intravenous Anaesthesia in Pediatric Patients
The objective of the study is to determine wether the use of the Bispectral Index Monitor (BIS) as a method to guide anaesthesia for children in different groups of age, undergoing ear nose and throat surgery anaesthetized with…
- Trial name
- NCT01043952
- Testing
- Propofol, Remifentanil, Bispectral Index Monitor
- Where
- Denmark
- Volunteers
- 157 people
- Sponsor
- Aalborg University Hospital
Progressive Infantile Idiopathic Scoliosis
Comparison of the Efficacy of Ketamine in Pediatric Patients With Idiopathic Scoliosis After Surgery
Comparison of the Efficacy of ketamine measuring the total consumption of morphine in pediatric patients with idiopathic scoliosis
- Trial name
- NCT02571491
- Testing
- Ketamine Hydrochloride, Remifentanil, Morphine hydrochloride
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Fundació Sant Joan de Déu
Anesthesia, Pediatric Anesthesia
Transition From Sevoflurane to Total Intravenous Anesthesia in Pediatric Patients
his prospective, observational, exploratory, and multicenter study aims to describe the evolution of propofol effect-site concentration administered via target-controlled infusion (TCI) based on the Eleveld model-with adjustments…
- Conditions
- Anesthesia, Pediatric Anesthesia, Total Intravenous Anesthesia
- Trial name
- TSTP (NCT07644260)
- Where
- 2 sites in Argentina
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas José de San Martín
Tooth Extractions
Comparison of Sufentanil and Remifentanil Infusion During General Anaesthesia for Removal of Wisdom Teeth in Ambulatory Surgery
Wisdom teeth removal under general anaesthesia is usually suitable for ambulatory surgery. The choice of opioid in dental day surgery is based on the need for a rapid and full recovery, as well as less morphine administration.
- Trial name
- SUF-REM-DDS (NCT01139671)
- Testing
- Remifentanil
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Clermont-Ferrand
Respiratory Distress Syndrome, Newborn
Surfactant Via Endotracheal Tube vs. Laryngeal Mask Airway (LMA) in Preterm Neonates With Respiratory Distress Syndrome
In this study, newborn babies with respiratory distress syndrome (RDS), receiving oxygen via nasal continuous airway pressure (CPAP) modalities, and needing surfactant treatment will be randomized to standard delivery of…
- Trial name
- NCT02164734
- Testing
- Endotracheal intubation, Laryngeal mask airway, remifentanil
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Albany Medical College
Oliceridine, Postoperative Cardiac Surgery
1.Comparison of the Analgesic Effect of Remifentanil Group and Different Dose Groups of Oliceridine in Postoperative Patients Undergoing Cardiac Surgery 2.Exploring the Hemodynamic Effects of Analgesic Regimens With Different Doses of Oliceridine After Cardiac Surgery
Cardiac surgery has the characteristics of long duration and large amount of intraoperative bleeding, easy to involve multiple organs and severe tissue injury, which is one of the most serious surgical procedures with…
- Trial name
- NCT06619145
- Testing
- Low dose Oliceridine, High dose Oliceridine
- Where
- 2 sites in China
- Volunteers
- 270 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Anesthesia, Pain
Near Infrared Spectroscopy Cortical Response to Noxious and Auditory Stimuli in Subjects Under General Anesthesia
The primary aim is to utilize near-infrared spectroscopy (NIRS) in patients under general anesthesia to measure changes in brain blood flow in the bilateral somatosensory cortices and the prefrontal cortices in response to…
- Trial name
- NCT02703090
- Testing
- Remifentanil, Normal saline
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Boston Children's Hospital
Effect of Anesthesia in Postoperative Pain, Effect of Anesthesia in Extubation Time
Opioid Versus Non-opioid Anesthesia for Ambulatory Surgery in Children
The investigators intend to study the safety and effectiveness of opioid free anesthesia compared to opioid anesthesia in ambulatory surgery in children, regarding postoperative pain, hemodynamic stability, agitation and…
- Conditions
- Effect of Anesthesia in Postoperative Pain, Effect of Anesthesia in Extubation Time, Effect of Anesthesia in Discharge Time From Postanesthesia Care Unit, Effect of Anesthesia in Postoperative Adverse Events
- Trial name
- NCT03979469
- Testing
- Ketamine, dexmedetomidine, fentanyl, remifentanil
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
Pain
Peritonsillar Infiltration With Levobupivacaine for Posttonsillectomy Pain
The investigators aimed to evaluate the effects of different concentrations of preincisional peritonsillar levobupivacaine (0.25% ve 0.5%) on postoperative pain and bleeding
- Trial name
- NCT02322346
- Testing
- Group S, Group LL, Group HL
- Volunteers
- 70 people
- Sponsor
- Ankara University
Hernia, Inguinal, Pain, Postoperative
Evaluating Pain Outcomes of Caudal vs Ilioinguinal Nerve Block in Children Undergoing Hernia Repair
Surgical intervention to treat a inguinal hernia is a very common pediatric surgical procedure, often performed using an inguinal incision.
- Trial name
- NCT03041948
- Testing
- Ilioinguinal/iliohypogastric nerve block, Caudal-epidural nerve block, Acetaminophen
- Where
- 2 sites in Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Delayed Emergence From Anesthesia
Propofol-Ketamine vs Remifentanyl-Ketamine for Sedation in Pediatric Patients Undergoing Colonoscopy
Ketamine and propofol have been used most frequently agents and remifentanil is used with increasing frequency in recent years. Investigators will compare ketamine-propofol and ketamine-remifentanyl effects on drug consumption…
- Trial name
- NCT02602743
- Testing
- Remifentanyl, Propofol, Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Healthy
Emergency Agitation in T&A
Sevoflurane has been used commonly in pediatric anesthesia since 1990. However, it has caused more emergency agitation (EA) that other inhalation agents and the incidence is up to 80%.
- Trial name
- NCT01152476
- Testing
- remifentanil, normal saline
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Seoul National University Bundang Hospital