Clinical trials: type1diabetes
type1diabetes
Diabetes in African Youth
This RCT aims to improve T1D care in East African children and young adults by testing the hypothesis that enabling patients to continuously monitor glucose levels with flash CGM technology will improve glucose time-in-range…
- Trial name
- NCT05454176
- Testing
- Libre 2, Device for SMBG and Libre Pro
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- University of Minnesota
Type 1 Diabetes, type1diabetes
Reducing Innate Inflammation in New Onset Type 1 Diabetes
This study aims to determine whether Lactiplantibacillus plantarum 299v (Lp299v) supplementation will reduce systemic inflammation and prolong residual beta cell function in individuals newly diagnosed with Type 1 diabetes.
- Conditions
- Type 1 Diabetes, type1diabetes, Type 1 Diabetes Mellitus
- Trial name
- NCT04335656
- Testing
- Lactiplantibacillus plantarum
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Medical College of Wisconsin
Non-Nutritive Sweetener, Type 1 Diabetes
Cardiometabolic Effects of Non-Nutritive Sweeteners (NNS) in Type 1 Diabetes (T1D)
This project will apply a novel non-nutritive sweetener (NNS) dietary assessment tool with measurement of circulating NNS levels in a pediatric population, allowing correlation of NNS exposure to clinically meaningful…
- Conditions
- Non-Nutritive Sweetener, Type 1 Diabetes, type1diabetes, Type 1 Diabetes Mellitus
- Trial name
- NCT07434544
- Testing
- Cherry Sports Drink
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Type1diabetes
Teamwork, Targets, Technology, and Tight Control in Newly Diagnosed Pediatric T1D - 4T Study
The 4T program encompasses: Teamwork, Targets, Technology, and Tight Range. These methods will help patients better manage their condition of Type 1 Diabetes with improved patient-reported outcomes.
- Trial name
- NCT04336969
- Testing
- 4T Education and Care
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Stanford University
type1diabetes
Remote Digital Care Effects in Adolescents With Type 1 Diabetes
Pilot study to evaluate effects of an experimental additional remote digital care (TELEDUC-DIAB) to adolescents with poorly controlled type 1 diabetes using digital monitoring platform and educative app
- Trial name
- TELEDUC-DIAB1 (NCT05421715)
- Testing
- TELEDUC-DIAB
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Toulouse
Type1diabetes
Mesenchymal Stromal Cells to Treat Type 1 Diabetes in Children and Adolescents
This is a combined phase 1 and 2 study in 66 subjects, male or female, between 7-21 years of age that have recently (< 6 months) been diagnosed with type 1 diabetes.
- Trial name
- NCT05061030
- Testing
- the ATMP Protrans
- Where
- Sweden
- Volunteers
- 66 people
- Sponsor
- Uppsala University Hospital
Type1diabetes, Diabetes
China Diabetes Type 1 Study (CD1S) by China Alliance for Type 1 Diabetes
The aim of the China Diabetes Type 1 Study (CD1S) is to conduct a nationwide type 1 diabetes (T1D) registry study in patients with T1D and in pediatric adolescent patients with diabetes who had an age of onset <= 20 years.
- Trial name
- NCT05498974
- Testing
- Standard type 1 diabetes management model constructed by China Alliance for Type 1 Diabetes in each center
- Where
- 11 sites in China
- Volunteers
- 20,000 people
- Sponsor
- Second Xiangya Hospital of Central South University
Celiac Disease in Children, Autoimmune Diseases
Gluten Reduction and Risk of Celiac Disease
Celiac disease shares many features of other autoimmune diseases such as type 1 diabetes. Recently, it was published that higher amounts of gluten intake increased the risk for celiac disease.
- Conditions
- Celiac Disease in Children, Autoimmune Diseases, type1diabetes
- Trial name
- GRAIN (NCT04593888)
- Testing
- Gluten reduced diet
- Where
- Sweden
- Volunteers
- 1,141 people
- Sponsor
- Lund University
Type1diabetes
Crosstalk Between Mucosal-Associated Invariant T (MAIT) Cells and the Gut Microbiota and Mucosa in the Development of Type 1 Diabetes in Children
To investigate in a prospective way changes in Mucosal-Associated Invariant T (MAIT) cells frequency, phenotype and function in link with the gut microbiota, gut integrity and the presence of Coxsackie virus B in two cohorts of…
- Trial name
- MAIT-DT1 (NCT05054361)
- Testing
- MAIT cells analysis, MAIT cytokines production analysis, Lactulose/Mannitol Test
- Where
- 2 sites in France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Lipodystrophy Acquired, Type1diabetes
Cyclophosphamide in the Treatment of Associated Acquired Lipodystrophy Syndrome With Type 1 Diabetes
This study evaluates the change of insulin resistance and glucose metabolism of patients with panniculitis associated acquired lipodystrophy syndrome and type 1 diabetes with the treatment of cyclophosphamide.
- Trial name
- NCT03936829
- Testing
- Cyclophosphamide
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Fudan University
Type1diabetes, Diabetes Mellitus, Type 1
Genetics Of Autoimmunity In Type I Diabetes
The purpose of this study is to gain more information about the step-by-step process that causes someone to develop type 1 diabetes.
- Conditions
- Type1diabetes, Diabetes Mellitus, Type 1, Type1 Diabetes Mellitus, Diabetes Mellitus
- Trial name
- NCT03648918
- Testing
- Blood Collection
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Type1diabetes
Skeletal Fragility in Type 1 Diabetes: Glycemic Control and Bone Strength
The purpose of this research study is to find out how bones are affected in children and adolescents with type 1 diabetes (T1D) as compared to children and adolescents without type 1 diabetes.
- Trial name
- NCT04289727
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Columbia University
Type1diabetes
Petit Cactus Study
The goal of this trial is to test a newly developed carbohydrate counting mobile application (named Petit Cactus) with photo recognition, for people with type 1 diabetes. To evaluate Petit Cactus, our objectives are: 1.
- Trial name
- NCT07380802
- Testing
- Petit Cactus
- Where
- Canada
- Volunteers
- 73 people
- Sponsor
- McGill University
Small for Gestational Age at Delivery, Gestational Diabetes
The CanDo (Canadian Donor Milk) Trial
The goal of this clinical trial is to learn about the impact of donor milk vs formula supplementation on human milk feeding and the health outcomes of infants who require supplementation in well-baby units.
- Conditions
- Small for Gestational Age at Delivery, Gestational Diabetes, type1diabetes, Type2diabetes
- Trial name
- NCT06315127
- Testing
- Human donor milk, Formula
- Where
- 3 sites in Canada
- Volunteers
- 112 people
- Sponsor
- Mount Sinai Hospital, Canada
Type1diabetes
Adherence to Mediterranean Diet in Type 1 Diabetes Initiating Minimed 780G: Glucose Metrics vs Insulin Metrics, is There a Difference
In this observaltional study, 240 patients aged >12 years old with T1DM who are on multiple daily injections or insulin pump and are scheduled to start using MiniMed 780G system will be included.We aim to compare patients'…
- Trial name
- NCT06646107
- Testing
- MInimed 780G
- Where
- Greece
- Volunteers
- 240 people
- Sponsor
- Attikon Hospital
Type 1 Diabetes, Type1diabetes
Probiotics in Newly Diagnosed T1D
The investigators aim to further the understanding of environmental factors that underlie the development of Type 1 diabetes (T1D) and the post-onset disease trajectory.
- Conditions
- Type 1 Diabetes, Type1diabetes, Type 1 Diabetes Mellitus
- Trial name
- NCT04141761
- Testing
- Visbiome
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Medical College of Wisconsin
Type1diabetes, Low Carbohydrate Diet
Metabolic Changes Induced by a Very Low Carbohydrate Diet in Youth With Type 1 Diabetes
As more adolescents with type 1 diabetes (T1D) opt to follow very low carbohydrate diets to improve glucose control, it is becoming increasingly important to study the metabolic and neurological changes that occur on these diets…
- Trial name
- NCT04955691
- Testing
- low carbohydrate diet, standard carbohydrate diet
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Yale University
Diabetes Complications, type1diabetes
Early Detection of Long-term Diabetic Complications in Children and Adolescents With Type 1 Diabetes
Aims: To investigate early markers of long-term diabetic complications and the association to an extended glucose metabolic profile comprising glucose control (current and past), glucose variability and insulin sensitivity in…
- Conditions
- Diabetes Complications, type1diabetes, Children, Only, Diabetic Neuropathies
- Trial name
- NCT05159856
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Steno Diabetes Center Copenhagen
Type1diabetes
4T Sustainability Program
The goal of the 4T program is to implement proven methods and emerging diabetes technology into clinical practice to sustain tight glucose control from the onset of type 1 diabetes (T1D) and optimize patient-reported and…
- Trial name
- NCT06314048
- Testing
- CGM and RPM
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Stanford University
Type1diabetes, Therapeutic Play
The Effect of Therapeutic Play on Anxiety and Fear Levels in Children With Diabetes
The study will be conducted using a randomized controlled method. Children with type 1 diabetes who are admitted to the Pediatric Endocrinology Service will be divided into two groups by randomization method.
- Conditions
- Type1diabetes, Therapeutic Play, Fear State, Anxiety State
- Trial name
- NCT06418269
- Testing
- Therapeutic Play
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa