Clinical trials: Varicose Veins
Portal Hypertension, Cirrhosis
Esophageal Capsule Endoscopy in Children
The portal hypertension (PHT) is the main complication in patients presenting with cirrhosis. It can be the direct cause of bleeding by rupture of the esophageal or gastric varices and can also contribute to the development of…
- Trial name
- PREVOCAP (NCT01551966)
- Testing
- Wireless esophageal capsule endoscopy ( PillCam Eso2)
- Where
- 7 sites in France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Liver Cirrhosis, Portal Vein
Effect of Portal Vein Thrombosis on the Prognosis of Liver Cirrhosis
The prevalence of portal vein thrombosis (PVT) in patients with liver cirrhosis is 5-20%. Current evidence regarding the effect of portal vein thrombosis on the prognosis of cirrhotic patients remains under debate.
- Conditions
- Liver Cirrhosis, Portal Vein, Venous Thrombosis, Varicose Veins
- Trial name
- NCT02335580
- Testing
- Somatostatin and its analogs, Endoscopic sclerotherapy, endoscopic variceal ligation, endoscopic tissue glue injection
- Where
- China
- Volunteers
- 475 people
- Sponsor
- General Hospital of Shenyang Military Region
Varicose Veins of Lower Limb, Thromboses, Venous
Prospective Cohort Study for Varicose Veins Incidence and Natural Course
A prospective study of individuals without varicose veins and who have primary varicose veins to assess the morbidity, risk factors and natural course of chronic lower limb vein disease.
- Conditions
- Varicose Veins of Lower Limb, Thromboses, Venous, Venous Insufficiency
- Trial name
- VINCI (NCT04546750)
- Where
- Russia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Russian Phlebological Association
Lipodermatosclerosis, Chronic Venous Insufficiency
Copper Impact on Venous Insufficiency and Lipodermatosclerosis
Venous disease has an adverse impact on the quality of life of patients and the NHS spends considerable resources on this chronic condition.
- Conditions
- Lipodermatosclerosis, Chronic Venous Insufficiency, Venous Insufficiency, Varicose Veins
- Trial name
- CIVIL (NCT03283800)
- Testing
- Copper impregnated compression stocking, Normal compression stocking
- Volunteers
- 16 people
- Sponsor
- Croydon Health Services NHS Trust
Esophageal Varices, Portal Hypertension
Non-invasive Predictors of Esophageal Varices and Their Correlation to Upper Endoscopic Findings
The goal of this observational study: To evaluate the diagnostic accuracy of non-invasive markers in predicting the presence and grading of esophageal varices in children with portal hypertension.
- Trial name
- NCT07464522
- Volunteers
- 51 people
- Sponsor
- Assiut University
Survival and Control of Bleeding
San Diego Bleeding Esophageal Varices Study
In unselected cirrhotic patients with bleeding esophageal varices to compare the influence on mortality rate, duration of life, quality of life, and economic costs of treatment of: Emergency portacaval shunt, and Emergency and…
- Trial name
- NCT00690027
- Testing
- Emergency portacaval shunt, Emergency and long-term endoscopic sclerotherapy
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- University of California, San Diego
Esophageal Varices
Noninvasive Methods For Prediction of Esophageal Varices in Children
The aim of this study is to use non-invasive methods to identify patients at risk of developing gastrointestinal varices and correlation of these non-invasive methods with the degree of esophageal varices and the presence or…
- Trial name
- NCT05781828
- Testing
- Detailed abdominal ultrasound
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Gastric Bleeding, Cirrhosis
Endoscopic Sclerotherapy and/or Ligation Versus Portacaval Shunt for Bleeding Gastric Varices
In unselected cirrhotic patients with bleeding gastric varices to compare the influence on mortality rate, duration of life, control of bleeding, quality of life, and economic costs of treatment of: portacaval shunt, endoscopic…
- Trial name
- NCT00820781
- Testing
- Portacaval shunt, Sclerotherapy
- Where
- United States
- Volunteers
- 518 people
- Sponsor
- University of California, San Diego
Venous Stasis Ulcer, Quality of Patient Care
Venous Leg Ulcer and Lymphedema Registry
This is an observational, longitudinal real world registry of venous leg ulcers created from electronic health record data obtained in the course of clinical care.
- Trial name
- VLULR (NCT02813187)
- Testing
- cellular and tissue based therapy, debridement, advanced wound therapy
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- U.S. Wound Registry
Lymphocele, Varicose Veins
Management of a Giant Lymphocele Following Varicose Vein Surgery - A Case Report
A 48-year-old female presented to the plastic surgery outpatient department (OPD) with a history of painful, progressive swelling of the right groin and medial aspect of the right thigh for 4 months.
- Trial name
- NCT05398458
- Testing
- Lymphocele excision and space obliterated by pedicle Gracilis muscle only flap
- Where
- Pakistan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Bahria International Hospital
Pelvic Congestive Syndrome, Pelvic Varices
Endovascular Versus Medical Treatment for the Pelvic Congestion Syndrome
Compare the efficacy and safety of endovascular treatment with sandwich technique (controlled release coils and 2% polidocanol foam) associated with diosmin-hisperidine and ibuprofen medical treatment and only the best chronic…
- Conditions
- Pelvic Congestive Syndrome, Pelvic Varices, Venous Disease
- Trial name
- ENDPCS (NCT04358497)
- Testing
- Medtronic® Concerto® detachable coil system, sclerosis, Diosmin / Hesperidin
- Volunteers
- 120 people
- Sponsor
- Hospital de Clínicas Dr. Manuel Quintela
Sickle Cell Leg Ulcer
Test of the Safety, Effectiveness, & Acceptability of An Improvised Dressing for Sickle Cell Leg Ulcers in the Tropics
One in 300 Jamaicans have HbSS sickle cell disease, and of these, up to 70% will suffer from sickle cell leg ulcers (SCLUs). Of these, 24% will have a chronic SCLU (one lasting longer than 6 months).
- Trial name
- SCLUJamaica (NCT04479618)
- Testing
- Usual Practice, Improvised dressing, Advanced dressing
- Where
- Jamaica
- Volunteers
- 48 people
- Sponsor
- Benskin, Linda, PhD, RN, SRN (Ghana), CWCN, CWS, DAPWCA
Venous Leg Ulcer
Intermittent Pneumatic Compression of the Thigh
Study Summary A leg ulcer is a long-lasting (chronic) sore that takes more than two weeks to heal. The majority of leg ulcers are caused either by problems with the veins in the legs; these are called 'venous leg ulcers' (VLU)…
- Trial name
- IPCOTT (NCT05659394)
- Testing
- Standard Wound Care Alone, Stand Wound Care plus IPC
- Where
- 5 sites in United States
- Volunteers
- 136 people
- Sponsor
- Huntleigh Healthcare Ltd
Esophageal Varices in Cirrhosis of the Liver, Upper Gastrointestinal Bleeding
Endoscopic Variceal Ligation in Children
This is an ambispective single-center cohort study of pediatric patients with portal hypertension and esophageal varices. The study was designed to evaluate the efficacy and safety of primary prophylaxis with endoscopic variceal…
- Conditions
- Esophageal Varices in Cirrhosis of the Liver, Upper Gastrointestinal Bleeding, Endoscopy, Child
- Trial name
- NCT03943784
- Testing
- Endoscopic Variceal Ligation, Non-Selective Beta-Blocking Agent
- Volunteers
- 60 people
- Sponsor
- Hospital Vall d'Hebron
Cirrhosis
Primary Prophylaxis of Gastric Varix Bleed
In patients who have never bled from gastric varix (GOV2 and IGV1), cyanoacrylate injection will be better than both beta-blocker therapy and no treatment in prevention of gastric variceal bleed.
- Trial name
- NCT00905996
- Testing
- Endoscopic cyanoacrylate injection, Beta-blocker (propranolol)
- Where
- India
- Volunteers
- 74 people
- Sponsor
- Govind Ballabh Pant Hospital
Cirrhosis
Beta-blockers for Prevention Of Growth Of Small Esophageal Varices In Cirrhosis: An Randomized Controlled Trial (RCT)
Background and Aims: The efficacy of portal pressure reduction by beta blockers for the management of small (≤5 mm) esophageal varices in patients of cirrhosis is not clear.
- Trial name
- NCT00772057
- Testing
- Propranolol
- Where
- India
- Volunteers
- 164 people
- Sponsor
- Govind Ballabh Pant Hospital
Cirrhosis Portal
Portal Vein Flow Velocity as a Screening Tool for Oesophageal Varices in Cirrhotic Patients
Portal vein flow velocity as screening tool for prediction of oesophageal varices in cirrhotic patient without upper endoscopy
- Trial name
- Portalflow (NCT05228509)
- Where
- 2 sites in Egypt
- Volunteers
- 75 people
- Sponsor
- Peter atef
Esophageal Varices
Optimal Time for Follow up After Variceal Band Ligation
Optimal time for follow up after variceal band ligation in cirrhotic patients remains to be determined
- Trial name
- NCT04602663
- Testing
- Esophageal Variceal Band ligation
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Tanta University
Liver Cirrhosis, Esophageal Varices
Two-dimensional Shear-Wave Elastography Evaluate Esophageal Varices Bleeding Risk of Liver Cirrhosis
The purpose of this retrospective study was to investigate the diagnostic performance of 2D-SWE for predicting the presence of esophageal varices and high-risk varices in patients with liver cirrhosis.
- Conditions
- Liver Cirrhosis, Esophageal Varices, Liver Stiffness
- Trial name
- NCT03989973
- Testing
- Gastroscopy
- Where
- China
- Volunteers
- 500 people
- Sponsor
- West China Hospital
Varicose Ulcer, Leg Ulcer
When Asking the Indication of a Skin Biopsy From a Patient With a Leg Ulcer in Primary Care?
Leg ulcers are frequent. There are no epidemiological studies available in France, but international studies estimate the prevalence between 0.045 and 0.63% of the total population, prevalence increases with age, reaching 5% of…
- Trial name
- BIOPULCER (NCT02889913)
- Testing
- No intervention only description
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph