Clinical trials: Vaccine Reaction
Vaccine Reaction, COVID-19
Determining Reactogenicity and Immunogenicity of Delayed COVID-19 Vaccine Schedule in Children
COVID-19 vaccine response data in children 5 to 11 years old remain scarce. Our understanding of the safety and immune responses including humoral and cellular responses generated in children remains limited.
- Conditions
- Vaccine Reaction, COVID-19, Children, Only
- Trial name
- NCT05329064
- Testing
- BNT162b2 Pfizer-BioNTech/Comirnaty
- Where
- Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Vaccine Adverse Reaction, COVID-19
Immunization of 7 Different Vaccines Against SARS-COV-2 Across 4 Countries.
Background: Scarce information exists in relation to the comparison of seroconversion and adverse events following immunization (AEFI) with different SARS-COV2 vaccines.
- Conditions
- Vaccine Adverse Reaction, COVID-19, Vaccine Reaction
- Trial name
- NCT05228912
- Testing
- COVID-19 Vaccines
- Where
- Mexico
- Volunteers
- 1,870 people, healthy volunteers welcome
- Sponsor
- Hospital Clinica Nova
Hepatitis B Vaccine Adverse Reaction
Efficacy of Hepatitis B Vaccine Boosters Among Neonatally Vaccinated Children in Chongqing
Worldwide, hepatitis B virus (HBV) infection is a major cause of acute hepatitis, and chronic infection with HBV often leads to chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma.
- Trial name
- NCT03867643
- Testing
- hepatitis B vaccine(HepB)
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Chongqing Medical University
Vaccine Adverse Reaction, Vaccine Reaction
Phase I/II, Open Label, Randomized, Safety and Immunogenicity Following DTwP-Hepatitis B-Hib-IPV Vaccine (Bio Farma) in Indonesian Infants
This trial is open label, comparative, randomized, phase I/II study, experimental, randomized, open-label, three arm parallel group study.
- Trial name
- NCT06690515
- Testing
- DTwP-Hepatitis B-Hib-IPV (Bio Farma) Vaccine Formula A, DTwP-Hepatitis B-Hib-IPV (Bio Farma) Vaccine Formula B, Registered DTwP-Hepatitis B-Hib Vaccine and IPV (Sinovac)®
- Where
- 3 sites in Indonesia
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- PT Bio Farma
Pain, Injection Site Reaction
Safety of Pediatric COVID-19 Vaccination
This is a prospective, observational study. During the study, children and adolescents (ages ≥ 5 to < 16) will be followed post administration of mRNA COVID-19 vaccines.
- Conditions
- Pain, Injection Site Reaction, Adverse Drug Event
- Trial name
- NCT05157191
- Testing
- Observational
- Where
- 5 sites in United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Duke University
SARS-CoV2 Infection, Vaccine Reaction
Assessment of the Immunization Levels Against Sars-Cov2 Virus in Subjects Who Have Received EU-approved COVID-19 Vaccines
Patients who voluntarily visit vaccination centers in Greece against COVID-19 are recruited and their immunization levels against Sars-Cov2 are assesed by measurement of the levels of serum antibodies against Sars-cov-2 before…
- Trial name
- NCT04954651
- Testing
- Approved vaccines against Sars-Cov2
- Where
- Greece
- Volunteers
- 1,000 people
- Sponsor
- University of Patras
Vaccination, Reaction - Vaccine
To Evaluate the Immunogenicity and Safety of Sequential Immunization Schedules of Sabin IPV and bOPV
The purpose of this study is to evaluate the immunogenicity and safety of sequential immunization schedules of Sabin IPV and bOPV.
- Trial name
- NCT04054492
- Testing
- Sabin-IPV+bOPV+bOPV, Sabin-IPV+Sabin-IPV+bOPV, Sabin-IPV+Sabin-IPV+Sabin-IPV
- Where
- China
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- China National Biotec Group Company Limited
Hand, Foot and Mouth Disease
A Clinical Trial for Inactivated Vaccine(Vero Cell) Against EV71 in Chinese Healthy Young Adults and Children
Hand, foot, and mouth disease (HFMD) is a common viral illness in infants and children caused by viruses that belong to the enterovirus genus of the picornavirus family.
- Trial name
- NCT01267903
- Testing
- vaccine against EV71 of 320U/0.5ml, vaccine against EV71 of 640U/0.5ml, vaccine against EV71 of 160U/0.5ml
- Volunteers
- 100 people
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Vaccination; Complications, Reaction, Serum
Dose of Hepatitis B Vaccines in Non/Low-response Populations
An interventional study will be performed in subjects aged 1-65 years old to evaluate effects of different doses of hepatitis B vaccines in low or non-response population.
- Trial name
- NCT01564134
- Testing
- hepatitis B vaccine
- Where
- 2 sites in China
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- Wu Jiang
BCG Vaccination Reaction, Tuberculosis
A Study of GC3107(BCG Vaccine) in Healthy Infants
The purpose of this study is to investigate the efficacy and safety of GC3107 in healthy infants
- Trial name
- NCT03947138
- Testing
- GC3107, Intradermal BCG SSI inj.
- Where
- 2 sites in South Korea
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Green Cross Corporation
Vaccine Reaction
Antibody Response and Longevity Post SARS-CoV-2 Vaccine (SARS-AB)
Longitudinal study on healthy subjects to investigate the longevity of the antibody response to the Pfizer-BioNTech COVID-19 vaccine.
- Trial name
- SARS-AB (NCT05515081)
- Testing
- blood sample collection
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Vaccine Adverse Reaction, Vaccination; Complications
Improving the School Vaccination Experience: What CARDs Are You Going to Play?
Vaccination hesitancy is identified as a threat to global health by the World Health Organization (WHO). For adolescents undergoing vaccination at school, prior studies demonstrate that concerns about pain and/or fear of needles…
- Conditions
- Vaccine Adverse Reaction, Vaccination; Complications, Fear
- Trial name
- NCT03966300
- Testing
- Multi-faceted knowledge translation intervention
- Where
- Canada
- Volunteers
- 1,919 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Vaccine Reaction, Vaccine Adverse Reaction
Immunogenicity and Safety Following In-House Recombinant Hepatitis B Vaccine in Indonesian Population (Phase III)
This is a phase 3, experimental, randomized, observer-blind, lot to lot consistency study. The primary objective of this study is to assess the protectivity of In-House Recombinant Hepatitis B vaccine 28 days after 3 doses…
- Trial name
- NCT05482295
- Testing
- In-House Recombinant Hepatitis B (Bio Farma) vaccine, Registered Hepatitis B vaccine recombinant (Engerix-B)
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- PT Bio Farma
Vaccination Reaction
Early Antibiotic Therapy and Vaccinations in Preterm Infants
Since the neonatal sepsis is still one of the most common causes of death in preterm infants up to 80% receive an perinatal antibiotic treatment.
- Trial name
- NCT05563753
- Testing
- ABT
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- University Hospital Tuebingen
Vaccine Reaction
Booster Effect of mRNA Vaccine on Antibody Response for SARS-CoV-2 After Complete Vaccination With Sinos
In most parts of the world, mRNA vaccines were used to provide protection to population against COVID 19. However, in some countries, including Pakistan, traditional viral vaccines named as Sinovac and Sinopharm were used for…
- Trial name
- NCT05213455
- Testing
- booster vaccine for COVID 19
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Lahore General Hospital
Vaccine Reaction
Safety and Immunogenicity of HPV Vaccine Administered Intradermally and Intramuscularly Via Needle-Free Injection System
The goal of this clinical trial is to evaluate the safety and immunogenicity of an HPV Vaccine (Gardasil) delivered by intramuscular needle-free injection and intradermal needle-free injection.
- Trial name
- NCT06142461
- Testing
- Gardasil, PharmaJet Stratis® Needle-Free Injection System, PharmaJet Tropis® Needle-Free Injection System
- Where
- Indonesia
- Volunteers
- healthy volunteers welcome
- Sponsor
- PharmaJet, Inc.
Epileptic Seizures Related to Drugs, SARS-CoV-2 Acute Respiratory Disease
Epileptic Seizure in Epilepsy Patients After SARS-CoV-2 Vaccination
Background and Objectives: Seizure attack is one of adverse effects of vaccination in epileptic patients, the risk of which after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inoculation was elucidated in the…
- Conditions
- Epileptic Seizures Related to Drugs, SARS-CoV-2 Acute Respiratory Disease, Vaccine Adverse Reaction
- Trial name
- NCT05341713
- Testing
- inactive SARS-Cov-2 vaccine
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital
Vaccine Reaction, Vaccine Adverse Reaction
Safety and Immunogenicity of SARS-CoV-2 Protein Subunit Recombinant Vaccine in Healthy Children
A Phase III, Observer-blind, randomized, active-controlled prospective intervention study
- Trial name
- NCT05546502
- Testing
- SARS-CoV-2 Protein Subunit Recombinant Vaccine, Active Comparator
- Where
- 10 sites in Indonesia
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- PT Bio Farma
Covid19, Vaccine Reaction
Post COVID-19 Vaccination Analysis in Healthcare Worker Recipients
This research study is studying how healthcare worker recipients react after receiving vaccinations for COVID-19. The objective of the study is to evaluate the immune response to COVID-19 vaccination.
- Trial name
- NCT04922944
- Testing
- COVID-19 vaccine
- Where
- United States
- Volunteers
- 167 people
- Sponsor
- Huntington Memorial Hospital
HIV Seropositivity, Immunodeficiency
Evaluation of Post-SARS-CoV-2 Vaccinal Response in Immunocompromised Patients
The aim of this study is to identify both the humoral immunological response through the detection of induced antibodies and the cellular immunological response through the detection of interferon gamma production by functional…
- Conditions
- HIV Seropositivity, Immunodeficiency, Vaccination Reaction, Covid19
- Trial name
- NCT05672654
- Testing
- Blood draw
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Ghent