Clinical trials: Urinary Tract Infection
Pneumonia, Bloodstream Infection
Clinical Outcomes in Patients With Infection by Resistant Microorganism
The goal of this individual patient data meta-analysis is to estimate the attributed and the associated health burden related to bloodstream infections, pneumonia, skin and soft tissue infections, surgical site infections and…
- Conditions
- Pneumonia, Bloodstream Infection, Urinary Tract Infections, Skin Infection
- Trial name
- NCT05880069
- Testing
- Pathogen resistant phenotype
- Where
- Spain
- Volunteers
- 5,000 people
- Sponsor
- Hospital Universitario Virgen Macarena
Urinary Tract Infections
Evaluation of the Effectiveness of Antibiotic Prophylaxis in Children With a Previous Urinary Tract Infection
Our hypothesis is that long-term antimicrobial prophylaxis does not reduce the recurrence of infection and the risk of appearance of kidney scars in children with a documented previous upper UTI.
- Trial name
- NCT00156546
- Testing
- antibiotic to reduce the recurrence of infection
- Where
- 16 sites in Italy
- Volunteers
- 660 people
- Sponsor
- University of Padova
Complicated Urinary Tract Infection, Infection
Single Dose Intravenous Antibiotics for Complicated Urinary Tract Infections in Children
Urinary tract infections (UTI) are commonly encountered in children, with 7% diagnosed with at least one UTI by the age of 19 years.
- Conditions
- Complicated Urinary Tract Infection, Infection, Pediatric Infectious Disease
- Trial name
- CHOICE UTI (NCT04876131)
- Testing
- Benzylpenicillin - single dose, Benzylpenicillin - three days, Gentamicin - single dose
- Where
- 7 sites in Australia, New Zealand
- Volunteers
- 396 people
- Sponsor
- Murdoch Childrens Research Institute
Meningitis, Bacterial, Bacterial Infections
Febrile Infants - Diagnostic Assessment and Outcome
The purpose of this study is to assess how clinicians apply guidance in the assessment of febrile infants presenting the the Emergency Department.
- Conditions
- Meningitis, Bacterial, Bacterial Infections, Urinary Tract Infections
- Trial name
- FIDO (NCT04196192)
- Where
- 6 sites in Ireland, United Kingdom
- Volunteers
- 555 people
- Sponsor
- Belfast Health and Social Care Trust
Urinary Tract Infections, Recurrent
Bovine Colostrum for Prophylaxis Against Recurrent Urinary Tract Infection in Children
Prebiotics as bovine colostrum are considered as a valuable supplement in the prevention of upper respiratory tract infections, gastrointestinal tract infections and neonatal sepsis.
- Conditions
- Urinary Tract Infections, Recurrent, Child, Prevention & Control
- Trial name
- NCT06164600
- Testing
- Bovine colostrum
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Febrile Urinary Tract Infection
Individualized Antibiotic Therapy in Children With Acute Uncomplicated Febrile Urinary Tract Infection
An investigator-initiated, open-label, multi-center, randomized, non-inferiority trial of children aged 3 months to 13 years with acute uncomplicated febrile urinary tract infection.
- Trial name
- NCT05301023
- Testing
- Individualized antibiotic therapy, Standard antibiotic therapy
- Where
- 8 sites in Denmark
- Volunteers
- 408 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Antibiotic Prophylaxis, Voiding Cystourethrogram
Antibiotic Prophylaxis to Prevent Post-procedure UTI After VCUG
The current practice of pre-VCUG antibiotic prophylaxis is highly variable. A recent unpublished survey of Society of Fetal Urologists (SFU) completed by this study team found that 87% of respondents reported having patients who…
- Conditions
- Antibiotic Prophylaxis, Voiding Cystourethrogram, Febrile Urinary Tract Infection
- Trial name
- APPrUV (NCT05438082)
- Testing
- Antibiotic Prophylaxis
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Urinary Tract Infections, Transplant-Related Disorder
Treatment Chronic UTI Post Kidney Transplant
Urinary tract infections (UTIs) with extended-spectrum -lactamase (ESBL)-positive Enterobacteriums (ESBL-E) are a common infectious complication of renal transplant recipients, with 10% of patients suffering from UTIs with ESBL-E…
- Trial name
- NCT05967130
- Testing
- Phage
- Where
- Iran
- Volunteers
- 5 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Neurogenic Bladder, Catheter-Related Infections
Antiseptic-coated Intermittent Urinary Catheter
Study design is a prospective, randomised, double-blind, and interventional. Primary aim of the study is to investigate efficacy of antiseptic-coated intermittent hydrophilic urinary catheters in prevention and reduction of…
- Trial name
- GuardianCath (NCT02697162)
- Testing
- Antiseptic-coated catheter, Hydrophilic catheter, Octenidine chloride
- Where
- Croatia
- Sponsor
- Children's Hospital Zagreb
Urinary Tract Infections
Evaluation of the Prevalence of E. Coli O Serotypes in Paediatric Population With Recurrent Urinary Tract Infection
This is a multicentre, observational, epidemiological study in which infants within the first 3 months of life with UTI and children aged ≥4 months with r-UTI will be recruited from nephrology /emergency departments and primary…
- Trial name
- rUTI (NCT06482151)
- Sponsor
- PENTA Foundation
Carbapenem Resistant Bacteria Infection
European Prospective Cohort Study on Enterobacteriaceae Showing Resistance to Carbapenems
Among antibiotic-resistant organisms, the Gram-negative bacteria are now the most important challenge because of the rapid worldwide spread of mechanisms conferring resistance to multiple drugs.
- Trial name
- EURECA (NCT02709408)
- Where
- 50 sites in Albania, Bulgaria and 9 more
- Volunteers
- 2,515 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Complicated Intra-abdominal Infection, Complicated Urinary Tract Infection
A Study to Learn About the Study Medicine Zavicefta After it is Released Into the Markets in Korea
The purpose of this study is to learn about the safety and effectiveness of Zavicefta once released into the markets in Korea. This study is to learn about Zavicefta in patients with difficult types of infections in the abdomen…
- Conditions
- Complicated Intra-abdominal Infection, Complicated Urinary Tract Infection, Hospital-acquired Pneumonia
- Trial name
- NCT05733104
- Where
- South Korea
- Volunteers
- 600 people
- Sponsor
- Pfizer
Urinary Tract Infection, Cellulitis
Perspectives on Antibiotics and Tracking Symptoms in Children
The study will assess families' perspectives and decision-making regarding the duration of oral antibiotic courses prescribed to children (4-17 years) who present with uncomplicated bacterial infections at the Royal Children's…
- Conditions
- Urinary Tract Infection, Cellulitis, Impetigo, Pharyngitis
- Trial name
- PATSy (NCT07093749)
- Testing
- Garmin Smartwatch
- Where
- Australia
- Volunteers
- 300 people
- Sponsor
- Murdoch Childrens Research Institute
Urinary Tract Infections
Fosfomycin Versus Standard of Care in Children With Antibiotic-resistant Urinary Tract Infections
Urinary tract infections (UTIs) are among the most common bacterial infections in children. Up to 50% of UTI's are caused by multi-drug resistant ESBL-producing gram negative bacteria that do not respond to treatment with oral…
- Trial name
- FosUTI (NCT05709028)
- Testing
- Fosfomycin, Standard of care antibiotics
- Where
- 5 sites in Australia
- Volunteers
- 300 people
- Sponsor
- University of Sydney
Kidney Transplantation, Bacteriuria
A Randomized Control Trial of Antibiotic Treatment Duration For Asymptomatic Bacteriuria After Kidney Transplantation
The major hypothesis to be tested is that there was no difference in the clinical outcome between 7(short-course) and 14(traditional-course) days of antibiotic treatment for asymptomatic bacteriuria early after kidney…
- Conditions
- Kidney Transplantation, Bacteriuria, Asymptomatic Infections
- Trial name
- NCT02575495
- Testing
- 7 days course of antibiotic treatment, 14 days course of antibiotic treatment
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Mahidol University
Sex Differences in Immune Response, Acute Inflammatory Diseases in Children
Study of the Sex Differences in Inflammatory Diseases in Children
Sexual differences in innate immune response have been demonstrated and were mainly attributed to the influence of the sex steroids (1-18).
- Trial name
- SepsiX (NCT04815811)
- Testing
- Blood collection, Stool collection
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- Queen Fabiola Children's University Hospital
Urinary Tract Infections, Vaginal Flora Imbalance
Vaginal Care System for Menopausal Women With Urinary Tract Infections
Menopausal women have an increased risk of recurrent urinary tract infections. This is likely due in part to hormonal changes occurring during menopause.
- Trial name
- NCT05573334
- Testing
- BioNourish
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Vaginal Biome Science
Urinary Tract Infections in Children, Diagnostic Techniques, Urological
Bladder Stimulation Technique for Urine Collection in the Pediatric Emergency Department
The purpose of this prospective, quasi-experimental study is to evaluate the efficacy of the Bladder Stimulation Technique (BST) compared to the traditional urine collection bag method in non-toilet-trained infants presenting to…
- Trial name
- NCT07654725
- Testing
- Bladder Stimulation Technique, Traditional Urine Bag Application
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people
- Sponsor
- Istanbul Medeniyet University
Nephrolithiasis, Urinary Tract Infection (UTI)
Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2
This study will be a multi-institutional randomized clinical trial of a short course of pre-operative antibiotic prophylaxis in addition to perioperative antibiotics prior to undergoing percutaneous nephrolithotomy.
- Conditions
- Nephrolithiasis, Urinary Tract Infection (UTI), Sepsis
- Trial name
- PNLABXPART2 (NCT02829060)
- Testing
- Nitrofurantoin 100 MG, 7d, Gentamicin, 5mg/kg, Ampicillin 2g
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- University of California, San Diego
Acute Pyelonephritis, Complicated Urinary Tract Infection
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Meropenem-Vaborbactam in Children With Complicated Urinary Tract Infection, Including Acute Pyelonephritis
The primary objective of the study is to assess the safety and tolerability of meropenem-vaborbactam administered by intravenous (IV) infusion in children 3 months and above to less than 12 years with complicated urinary tract…
- Trial name
- NCT06672978
- Testing
- Meropenem-Vaborbactam, Antibiotics
- Where
- 26 sites in United States, Bulgaria and 4 more
- Volunteers
- 66 people
- Sponsor
- Rempex (a wholly owned subsidiary of Melinta Therapeutics, LLC)