Clinical trials: Upper Extremity Dysfunction, open to volunteers
Male Erectile Disorder, Prostate Cancer
Focal Therapy for Prostate Cancer Using HIFU
RATIONALE: Prospective trials using hemi-ablation with high intensity focused ultrasound (HIFU) (Sonablate 500) have demonstrated feasibility, safety, and encouraging functional outcomes and early cancer control with 90% of men…
- Conditions
- Male Erectile Disorder, Prostate Cancer, Therapy-related Toxicity, Urinary Incontinence
- Trial name
- INDEX (NCT01194648)
- Testing
- questionnaire administration, assessment of therapy complications, high-intensity focused ultrasound ablation
- Where
- United Kingdom
- Volunteers
- 354 people
- Sponsor
- University College, London
Mild Cognitive Impairment (MCI), Moderate Cognitive Impairment
Comparative Effects of Integrated Versus Sequential Approaches to Dual-Task Training in Elderly With Mild to Moderate Cognitive Impairment
Mild and Moderate cognitive impairment is a condition characterized by a noticeable decline in cognitive abilities, including memory and thinking skills, which is greater than expected for an individual's age but does not…
- Trial name
- nill (NCT07775079)
- Testing
- Integrated Dual-Task Training, Sequential Dual-Task Training
- Where
- Pakistan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Shifa Tameer-e-Millat University
Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric)
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
Researchers are looking for a better way to treat children and young adults who have heart failure with left ventricular systolic dysfunction (LVSD).
- Trial name
- FIORELLO (NCT07192952)
- Testing
- Finerenone (Kerendia, BAY94-8862)
- Where
- 132 sites in United States, Argentina and 21 more
- Volunteers
- 117 people
- Sponsor
- Bayer
Cerebral Palsy Infantile, Chronic Pain
Trunk and Upper Extremities Program Effect in Decreasing Compensation Patterns in Unilateral Cerebral Palsy Children
The goal of this clinical trial is to test the effectiveness of a trunk and upper extremities exercise program. The main questions it aims to answer are: Whether the program decreases compensation patterns in unilateral cerebral…
- Conditions
- Cerebral Palsy Infantile, Chronic Pain, Upper Extremity Dysfunction
- Trial name
- TUPEX (NCT06069765)
- Testing
- TUPEX
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fundacio Aspace Catalunya
Cerebral Palsy (CP), Brain Injuries
Acceptability of Paediatric Wrist Orthoses Through Co-design
The goal of this pilot interventional study (pre-post design) is to learn if a co-designed wrist-hand orthosis can improve acceptability compared to a conventional orthosis in children aged 6 to 14 years with neuromotor disorders…
- Conditions
- Cerebral Palsy (CP), Brain Injuries, Neuromotor Dysfunction
- Trial name
- NCT07861958
- Testing
- Orthosis acceptability
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- IRCCS Eugenio Medea
Hemiplegic Cerebral Palsy, Mirror Hands
Mirror Therapy in Children With Hemiparetic Cerebral Palsy
Cerebral palsy (CP) is a neurodevelopmental disorder that frequently impairs upper extremity motor control and hand function, resulting in limitations in daily activities.
- Conditions
- Hemiplegic Cerebral Palsy, Mirror Hands, Upper Extremity Dysfunction, Motor Activity
- Trial name
- NCT07734376
- Testing
- Mirror Therapy, Conventional Physiotherapy
- Volunteers
- 26 people
- Sponsor
- Marmara University
Autoimmune Diseases, Epilepsy
VNS Prospective Neuromodulation of Immune and Gastrointestinal Systems
Vagal nerve stimulation is a neurosurgical procedure consisting of implantation of an impulse generator battery with leads placed into the vagus nerve in the neck.
- Conditions
- Autoimmune Diseases, Epilepsy, Autonomic Dysfunction, Inflammatory Bowel Diseases
- Trial name
- VNS-IG (NCT03953768)
- Testing
- Vagal nerve stimulation (VNS)
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Louisville
Chronic Granulomatous Disease (CGD)
Open-label Gene Therapy Study in p47-CGD
Chronic granulomatous disease (CGD) caused by p47phox deficiency (p47-CGD) is a life-threatening genetic disorder causing nicotinamide adenine dinucleotide phosphate (NADPH) oxidase deficiency in phagocytes.
- Trial name
- NCT07826767
- Testing
- SGX-001
- Where
- 3 sites in Germany, Spain and 1 more
- Volunteers
- 5 people
- Sponsor
- Somagenetix AG