Clinical trials: Typical Development
Autism Spectrum Disorder, Autism
Mitochondrial Dysfunction in Autism Spectrum Disorder
Researchers at Arkansas Children's Hospital Research Institute are conducting a study about mitochondrial function in children. The study involves up to 5 visits to Arkansas Children's Hospital with fasting blood draws…
- Conditions
- Autism Spectrum Disorder, Autism, Mitochondrial Disease, Developmental Delay
- Trial name
- Mito (NCT02000284)
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Typically Developing Children Ages 3 to 6
Language Learning and Language Experience
The goal of this clinical trial is to learn if text can support children in learning new verbs in healthy children ages three through six.
- Trial name
- NCT06645145
- Testing
- Orthographic facilitation
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Montclair State University
Development Coordination Disorder, Typical Developed Children
Movement Strategies During Balance Tasks in Children With and Without Developmental Coordination Disorder
The main objective of the study is to gain insights in how children learn a balance task and whether there is a difference between children with and without Developmental Coordination Disorder.
- Trial name
- NCT06802094
- Testing
- Single-session balance intervention in virtual reality
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Bipolar Disorder, Attention Deficit Disorder With Hyperactivity
Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healthy Controls
The purpose of this research is to learn more about how children with mental health problems, including bipolar disorder (BD), attention deficit hyperactivity disorder (ADHD), and generalized anxiety disorder (GAD), differ from…
- Conditions
- Bipolar Disorder, Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder Without Hyperactivity, Generalized Anxiety Disorder
- Trial name
- BBPP (NCT01570426)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Bradley Hospital
Oppositional Defiant Disorder, Conduct Disorder
Resources to Enhance the Adjustment of Children (REACH)
This continuation study evaluates the long-term outcomes of multimodal, modular interventions with early-onset behavior disordered children and innovative methods to promote the maintenance and extension of treatment effects…
- Conditions
- Oppositional Defiant Disorder, Conduct Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- REACH (NCT00820001)
- Testing
- Booster Treatment, No-Booster, No intervention
- Where
- 2 sites in United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Autism
Clinical Evaluation of Integrative Practices Units Infant and Child Care for Unit Children With Typical or Atypical Autism (AUTISM)
The research project is part of the evaluation of the therapeutic approaches in mental health. Its framework infant and juvenile units that have developed "integrative devices," taking into account recent advances in knowledge…
- Trial name
- AUTISM (NCT02154828)
- Testing
- Integrative practices
- Where
- 21 sites in France
- Volunteers
- 103 people
- Sponsor
- Nantes University Hospital
CHILD
Exploration of Sensory-motor Representations in Children of Typical Development Aged 5 to 8
Evaluate the quality of sensorimotor representations in typically developing children aged 5 to 8 years.
- Trial name
- IMOT (NCT05300100)
- Testing
- sensorimotor activities
- Where
- 5 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Lens
Developmental Language Disorder and Language Impairment
Recasting or Book Reading by Parents or Clinicians
Developmental Language Disorder (DLD) affects approximately seven percent of the population and is characterized by grammatical deficits that cascade into lifelong academic challenges and under-employment.
- Trial name
- NCT05099328
- Testing
- Recast Therapy, Syntax Stories
- Where
- 2 sites in United States
- Volunteers
- 137 people
- Sponsor
- University of Delaware
Autism Spectrum Disorder
Characterization of (A)Typical Sensorimotor Pathways in Individuals With Autism
The goal of this interventional study is to understand whether sensorimotor skills could represent an endophenotype for autism, i.e.
- Trial name
- MovAUT (NCT07389720)
- Testing
- clinical assessment, Neuropsychological examination, Neurophysiological evaluation
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Children With Autism Spectrum Disorder, Typical Developed Children
Investigating Handwriting Characteristics and Underlying Factor in Children With Autism Spectrum Disorder
The mechanism of the motor problem in children with autism spectrum disorder (ASD) in handwriting has been investigated in the following three aspects, including collecting dynamic handwriting performance, exploring the related…
- Trial name
- NCT06228885
- Testing
- handwriting experiment and motor ability test
- Where
- Taiwan
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Scald Burn Injuries
Behaviors of Children Ages 15 Months to Five Years Around Microwave Ovens
The purpose of this study is to assess the typical behavior of children ages 15 months to five years around a microwave oven. The UCH Burn and Complex Wound Center has observed scald burn injuries in young children operating…
- Trial name
- NCT01112124
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Children With Typical Development
OUT to IN: an Outdoor Body-oriented Intervention Program
The goal of this randomized trial is to examine the effects of a body-oriented intervention program on preschoolers' social-emotional competence.
- Trial name
- NCT05756374
- Testing
- OUT to IN
- Where
- Portugal
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- University of Évora
Primary Disease Fascioscapulohumeral Dystrophy (FSHD)
Routine Health Care of Patients With FSHD
On the basis of published data and our results indicating that oxidative stress may contribute to the peripheral skeletal muscle dysfunction in patients with FSHD, investigators conducted a pilot randomized double-blind placebo…
- Trial name
- FSHD (NCT02622438)
- Testing
- Followed with an initial assessment, 12 months and followed annually corresponding to the usual follow-up of the patient.
- Where
- France
- Volunteers
- 189 people
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder, Healthy
Differences in Prosocial Behaviors and Related Brain Networks in Children With Autism and Typical Development
The goal of this observational study is to compare the brain functional network between children with autism and typical development, using magnetic resonance imaging (MRI), electroencephalogram/event-related potentials(EEG/ERPs)…
- Trial name
- NCT06908174
- Testing
- ADOS-2
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorder
Paediatric Autism Communication Therapy (PACT) in Children With Autism Spectrum Disorder
Paediatric Autism Communication Therapy (PACT) is a naturalistic developmental behavioural interventions to reduce autism symptoms.
- Trial name
- DAN-PACT (NCT05673096)
- Testing
- PACT, MAU
- Where
- 6 sites in Denmark
- Volunteers
- 280 people
- Sponsor
- University of Southern Denmark
Developmental Coordination Disorder
Rhythmic Interlimb Coordination in Children with Developmental Coordination Disorder
This study is a case-controlled observational study, involving children with Developmental Coordination Disorder (DCD) and typically developing children with an age from 8 up to 12 years old.
- Trial name
- NCT04891562
- Testing
- interlimb coordination of the lower limbs and synchronization
- Where
- Belgium
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Autism, Cerebral Palsy
Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers With and Without Cerebral Palsy
Background: New ways to study the brain as people move include near-infrared spectroscopy (NIRS) and electroencephalography (EEG).
- Trial name
- NCT03434080
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Child Mental Health, Behavioral Symptoms
Wellbeing and Resilience Among 1-3 Years Old Children of Mothers with Complex Mental Health Problems: a Pragmatic Clinical Trial of Online VIPP-SD Vs. Care As Usual
Children of parents with severe mental disorders have an increased risk of mental disorders themselves, with more than half of this population diagnosed with a mental health condition during their life time.
- Conditions
- Child Mental Health, Behavioral Symptoms, Child of Impaired Parents
- Trial name
- WellCom (NCT06795347)
- Testing
- Online VIPP-SD, Care As Usual
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Southern Denmark
Autism Spectrum Disorders
Cortical Metrics in Intervention Trials With Autism Spectrum Disorders
The investigators overarching aim is to obtain preliminary data to support a larger grant to validate a novel objective, physiologically-based outcome measure for clinical trials in autism spectrum disorders (ASDs) called the…
- Trial name
- NCT02212275
- Testing
- Dextromethophan
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Cerebral Palsy, Infant Development
Neuroimaging of Babies During Natural Sleep to Assess Typical Development and Cerebral Palsy
Background: Early diagnosis of cerebral palsy (CP) is crucial, enabling intervention when neuroplasticity is at its highest. Magnetic resonance imaging (MRI) plays a vital role in CP diagnosis.
- Conditions
- Cerebral Palsy, Infant Development, Development, Infant
- Trial name
- NIBS-CP (NCT06396520)
- Testing
- No intervention, observational
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danish Research Centre for Magnetic Resonance