Clinical trials: Type 1 Diabetes in Adolescence
Diabetes Mellitus, Type 1, Hypertension
The Effect of Melatonin on Early Signs of Hypertension in Teenagers With Diabetes Mellitus Type 1
Nocturnal hypertension is recognized via ambulatory blood pressure monitoring in adolescents with type 1 diabetes mellitus. Melatonin, (as previously seen in earlier studies in adults), may alter these changes, which may be a…
- Trial name
- NCT02644590
- Testing
- Melatonin
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Type 1 Pediatric Diabetes
Description of the Evolution of a Cohort of Adolescents With Type 1 Diabetes Following Their Participation in Therapeutic Education Program Based on Social Cognitive Theory: Socio-cognitive Profile, Physiological Behaviour of Therapeutic Adherence and Quality of Life
Introduction: Therapeutic Patient Education (TPE) is the key of the interdisciplinary management of type 1 diabetes for adolescents, favoring their adherence and improving their quality of life and metabolic control.
- Trial name
- ETPACAP (NCT02859818)
- Testing
- therapeutic education program
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Type 1 Diabetes
Happy Bob App: A Preliminary Evaluation of Its Use in Youth With Diabetes
The goal of this clinical trial is to evaluate the impact of peer support via the Happy Bob phone app in youth with Type 1 Diabetes.
- Trial name
- NCT06412601
- Testing
- RPM, app
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Type 1 Diabetes
Healthy And Positive Pathways for Young People With Type 1 Diabetes (HAPPY T1D)
In this 2-year randomized clinical trial, we will implement and assess the impact of a behavioral/psychoeducational intervention to reduce diabetes distress and improve glycemic outcomes in adolescents and young adults, aged…
- Trial name
- NCT05413239
- Testing
- Psychoeducation to reduce diabetes distress and improve glycemic outcomes
- Where
- 2 sites in United States
- Volunteers
- 217 people
- Sponsor
- Joslin Diabetes Center
Type 1 Diabetes
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 15 Weeks in Adolescents and Adults With Type 1 Diabetes
Closed-loop strategy is composed of three components: glucose sensor to read glucose levels, insulin pump to infuse insulin and a dosing mathematical algorithm to decide on the required insulin dosages based on the sensor's…
- Trial name
- NCT02846857
- Testing
- 15-week intervention with sensor-augmented pump, 15-week intervention with single-hormone closed-loop, 15-week intervention with dual-hormone closed-loop
- Sponsor
- Institut de Recherches Cliniques de Montreal
Type 1 Diabetes, Nephropathy, Diabetic
SGLT2 Adjunct in T1D
Effect of Sodium-Glucose Cotransporter (SGLT) 2 Inhibitors on Diabetic Nephropathy Progression in Adolescents with Type 1 Diabetes Mellitus
- Trial name
- NCT07591077
- Testing
- Empagliflozin (EMPA)
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Ain Shams University
Self Care
Evaluation of the Eversense Continuous Glucose Monitoring System in Type I Diabetic Youth
The purpose of this clinical investigation is to provide pilot clinical data to direct pivotal study development for the pediatric indication of the Senseonics Continuous Glucose Monitoring System (CGM) measurements when compared…
- Trial name
- FNH (NCT03815552)
- Testing
- Eversense Continuous Glucose Monitoring
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Kinderkrankenhaus auf der Bult
Type 1 Diabetes Mellitus (T1DM), Parent
Comprehensive Intervention to Promote Adjustment in Adolescents With Type 1 Diabetes and Their Parents During Transfer of Health Care Responsibility
Introduction: Type 1 diabetes mellitus is a health condition that produces physical and psychosocial alterations in both the person the person with diabetes mellitus and his or her family, that is why interventions should be…
- Conditions
- Type 1 Diabetes Mellitus (T1DM), Parent, Adolescent, Nursing
- Trial name
- NCT07886307
- Testing
- CONEXIÓN ADAPTAR - DM1, Usual Care
- Where
- 2 sites in Colombia
- Volunteers
- 34 people
- Sponsor
- Universidad de la Sabana
Type 1 Diabetes
Closing the Loop in People with Type 1 Diabetes
The main objective of this study is to determine whether home use of fully closed-loop glucose control applying age-approved ultra-rapid insulin (Phase 2) is superior to standard insulin pump therapy with continuous glucose…
- Trial name
- CLEAR Phase 2 (NCT05653050)
- Testing
- CamAPS HX, Standard insulin pump therapy with CGM
- Where
- 4 sites in United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Cambridge
Type 1 Diabetes
Effect of Vitamin D on the Honeymoon Period in Children and Adolescents With Type 1 Diabetes
The purpose of this study is to determine if supplementation with Vitamin D in children and adolescents with newly diagnosed type 1 diabetes increases the number of patients who enter the honeymoon period.
- Trial name
- NCT01724190
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Nationwide Children's Hospital
Diabetes Mellitus, Type 1
A Pilot Study of Biomarkers of Stress in Youth Who Use Teens.Connect
This feasibility/pilot study has three purposes. First, the investigators will determine the feasibility of collecting saliva to measure stress biomarkers over three days at home in youth.
- Trial name
- NCT02970656
- Testing
- Teens.Connect
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Yale University
Mental Health Issue, Diabetes Distress
Examining the Feasibility of Wysa in Hindi
The principal objective of this study is to investigate the feasibility of including a digital mental health intervention (Wysa in Hindi) within pre-existing usual care to support adolescents and young adults with Type 1 Diabetes…
- Trial name
- NCT06320756
- Testing
- Wysa in Hindi, Individual and group sessions on topics like motivation, coping, wellbeing
- Where
- India
- Volunteers
- 79 people
- Sponsor
- Wysa
Type 1 Diabetes
Low Carbohydrate Versus Mediterranean Diet in Adolescents With Type 1 Diabetes
The goal of this clinical trial is to compare the effect of low carbohydrate diet versus Mediterranean diet on blood sugar values in adolescents with type 1 diabetes.
- Trial name
- NCT05872711
- Testing
- Low carbohydrate diet
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Type 1 Diabetes
Adherence Intervention to Promote Optimal Use of Insulin Pumps in Adolescents With Type 1 Diabetes
The overall objective of this study is to address the critical need of improving insulin pump adherence in adolescents with Type 1 Diabetes (T1D) by providing personalized intervention using evidence-based techniques during…
- Trial name
- Pump It Up! (NCT02333539)
- Testing
- Adherence behaviors and recommendations for improvement., Adherence behavior that needs improvement is targeted
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Type 1 Diabetes Mellitus
A Study to Evaluate NBI-6024 in Adult and Adolescent Patients With New Onset of Type 1 Diabetes Mellitus
This was a study designed to evaluate the efficacy of multiple doses of an investigational drug, NBI-6024, in adult (18 to 35 years of age) and adolescent (10 to 17 years of age) patients with new onset type 1 diabetes mellitus…
- Trial name
- NCT00873561
- Testing
- NBI-6024
- Where
- 21 sites in Canada, Czechia and 6 more
- Volunteers
- 188 people
- Sponsor
- Neurocrine Biosciences
Type 1 Diabetes Mellitus, Diabetes Self-Management Education
DiaBuddy: AI-Enabled Digital Self-Management for Youth With Type 1 Diabetes
The goal of this clinical trial is to learn whether DiaBuddy, a digital self-management app, can help children and adolescents with Type 1 diabetes better manage their condition and reduce the burden experienced by their…
- Conditions
- Type 1 Diabetes Mellitus, Diabetes Self-Management Education, Caregiver Burden
- Trial name
- DiaBuddy (NCT07861373)
- Testing
- DiaBuddy: AI-Enabled Digital Self-Management Intervention, Usual Diabetes Care
- Volunteers
- 140 people
- Sponsor
- Dr. Juwayria Omar
Type 1 Diabetes, Adolescent Behavior
Incorporating Mind-body Skills With Diabetes Education in Adolescents With Type 1 Diabetes
Adolescence presents a challenging time for type 1 diabetes management, and despite a multitude of studies aimed at increasing disease compliance in this age group, none have been deemed superior.
- Trial name
- NCT05577169
- Testing
- Mind-body skills, Diabetes education
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Indiana University
Type1diabetes, Adolescent Behavior
Sleep, Glycemic Control, and Insulin Resistance in Adolescents With Type 1 Diabetes
Despite advancements in care, most adolescents with T1D have higher BMI and significantly higher HbA1c than recommended and are markedly IR, placing them at increased risk for CVD1,2.
- Conditions
- Type1diabetes, Adolescent Behavior, Sleep
- Trial name
- SunDIAL (NCT03832790)
- Testing
- observation
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Colorado, Denver
Type 1 Diabetes, Motivational Interviewing
The Impact of Motivational Interviews Conducted Through Tele-Nursing on Diabetes Management
The deterioration of glycemic control in adolescents with Type 1 diabetes (T1DM) is a genuine cause for concern. Possible reasons for worsening glycemic control in youth include lack of monitoring, inadequate self-care…
- Trial name
- NCT06208618
- Testing
- Education and Motivational Interviews
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Eskisehir Osmangazi University
Diabetes, Diabetes Mellitus, Type 2
Observational Study to Observe the Safety of Levemir® Treatment in Children and Adolescents With Type 1 Diabetes
This observational study is conducted in Europe. The trial aims to observe the incidence of serious adverse drug reactions in children and adolescents with type 1 diabetes during Levemir® treatment.
- Trial name
- PREDICTIVE™ (NCT00704574)
- Testing
- insulin detemir
- Where
- Sweden
- Volunteers
- 159 people
- Sponsor
- Novo Nordisk A/S