Clinical trials: Tremor
Essential Tremor
1-Octanol to Treat Essential Tremor
This study will determine the optimal dose of 1-octanol that will safely reduce tremors in patients with essential tremor-a disorder in which the hands, and sometimes the head, shake involuntarily.
- Trial name
- NCT00016679
- Testing
- 1-Octanol
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson Disease-tremor, Essential Tremor
Mapping Functional Networks of Brain Activity Using EEG in Patients With Essential Tremor or Parkinson Disease Before and After MR-guided Focused Ultrasound Thalamotomy for Tremor
A cornerstone in PD and ET research is the investigation of neurophysiological changes as potential bio-markers that could help in tracking disease progression and response to therapy.
- Trial name
- NCT02692183
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Essential Tremor
Essential Tremor in Children and Adolescent
Essential tremor (TE) is the most common abnormal movement of the adult. His diagnosis is based on a bundle of clinical arguments (Movement Disorders Society, 1998).
- Trial name
- NCT03487705
- Testing
- electromyographic essential tremor
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Montpellier
Parkinson Disease, PD
Genetic Characterization of Parkinson's Disease
This study will explore the risks and causes of Parkinson's disease, a chronic progressive nervous system disorder. Patients typically have tremors, muscle weakness and a shuffling gait.
- Conditions
- Parkinson Disease, PD, Movement Disorder, Healthy Volunteer
- Trial name
- NCT00105131
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Movement Disorders, Myoclonus
Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases
The purpose of this protocol is to identify families with inherited neurologic conditions, especially movement disorders, to evaluate affected and unaffected individuals clinically, and to obtain blood samples for genetic…
- Conditions
- Movement Disorders, Myoclonus, Nervous System Diseases, Tic Disorders
- Trial name
- NCT00001667
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson Disease
The Effect of Sifrol® on Tremor and Depression in Patients With Idiopathic Parkinson's Disease
Documentation of the effect of SIFROL® on tremor and depression as well as its tolerability in ambulatory patients suffering from idiopathic Parkinson's disease under routine conditions
- Trial name
- NCT02231294
- Testing
- Sifrol®
- Volunteers
- 1,464 people
- Sponsor
- Boehringer Ingelheim
Essential Tremor
Pathophysiology of Tremor-modulating Mechanisms of Propranolol and Primidone in Essential Tremor
Pathophysiology of tremor-modulating mechanisms of propranolol and primidone in essential tremor (ET) will be studied using accelerometry with electromyography (EMG), transcranial magnetic stimulation (TMS), and eyeblink…
- Trial name
- NCT04692844
- Testing
- Propranolol, Primidone
- Where
- Slovenia
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Essential Tremor
Chinese ET Registry (CETR)
The purpose of the Chinese Essential Tremor Registry (CETR) is to develop a database of patients with Essential tremor in China.
- Trial name
- NCT04198246
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xiangya Hospital of Central South University
Essential Tremor
Montreal Cognitive Assessment Index Following MRI Guided Focused Ultrasound Thalamotomy
We assessed Montreal Cognitive Assessment scores before and after MRI guided focused ultrasound thalamotomy for tremor in order to identify if there are changes in cognitive function following treatment.
- Trial name
- NCT06941285
- Testing
- Data collection
- Volunteers
- 142 people
- Sponsor
- Rambam Health Care Campus
Movement Disorder, Tremor
Natural History Protocol for Movement Disorders
Background: A movement disorder is a condition that causes a person s body to move in ways that are not normal. There are different types. Some disorders cause movements people can t control, such as tics or shaking.
- Conditions
- Movement Disorder, Tremor, Parkinson's Disease
- Trial name
- NCT05413291
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson Disease, Essential Tremor
Clinical Outcomes for Deep Brain Stimulation
The object of this study is to longitudinally collect clinical outcomes of patients receiving deep brain stimulation for movement disorders with the objective of making retrospective comparisons and tracking of risks, benefits…
- Conditions
- Parkinson Disease, Essential Tremor, Dystonia
- Trial name
- NCT03992625
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Washington University School of Medicine
Parkinson Disease
A Study to Analyze Symptoms Prevalent in Early PD (Dysphonia, Tremor)
This is a web-based study that involves monitoring hallmark symptoms of Parkinson's Disease (PD), specifically dysphonia and tremor, using smartphone sensor data.
- Trial name
- NCT04288804
- Testing
- Smartphone microphone sensor, Smartphone accelerometer sensor
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Goalspal LLC
Transcutaneous Vagal Nerve Stimulation (tVNS), Parkinson Disease (PD)
Effects of Transcutaneous Vagus Nerve Stimulation in Parkinson´s Disease
This study aims to determine whether electrical stimulation of the ear, when combined with physical and speech therapy, can improve symptoms in subjects diagnosed with Parkinson´s disease, by comparing two different application…
- Trial name
- tVNS_PD (NCT07588191)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS) of Vagus Nerve, Conventional Physical therapy, Conventional Speech Therapy
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Universidade da Coruña
Dystonia, Parkinson Disease
Lesioning Procedures for Movement Disorders
Dystonia is a rare syndrome with varying etiologies. Similarly, tremor conditions refractory to medical management and disabling that they need surgical interventions are rare in our setting.
- Conditions
- Dystonia, Parkinson Disease, Essential Tremor
- Trial name
- NCT06352268
- Testing
- Pallidal, subthalamic or thalamic lesioning
- Where
- India
- Volunteers
- 250 people
- Sponsor
- All India Institute of Medical Sciences
Parkinson Disease, Essential Tremor
Deep Brain Stimulation (DBS) Retrospective Outcomes Study
The primary objective of this study is to characterize real-world clinical outcomes of Deep Brain Stimulation (DBS) using retrospective review of de-identified patient records.
- Conditions
- Parkinson Disease, Essential Tremor, Dystonia
- Trial name
- NCT03664609
- Testing
- Deep Brain Stimulation
- Where
- 20 sites in United States, Belgium and 4 more
- Volunteers
- 5,000 people
- Sponsor
- Boston Scientific Corporation
Laryngeal Dystonia, Unaffected Relatives of Laryngeal Dystonia Patients
Imaging Genetics of Laryngeal Dystonia
The contribution of genetic risk factors to the development of focal dystonias is evident. However, understanding of how variations in the causative gene expression lead to variations in brain abnormalities in different…
- Conditions
- Laryngeal Dystonia, Unaffected Relatives of Laryngeal Dystonia Patients, Voice Tremor, Muscle Tension Dysphonia
- Trial name
- NCT03042975
- Testing
- MRI, Blood draw
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- Kristina Simonyan
Parkinson's Disease, Obsessive Compulsive Disorder
Physiological Brain Atlas Development
The NIH grant has funded the development of a physiological brain atlas registry that will allow us to significantly improve the data collectioin and use of physiological data into a normalized brain volume.
- Conditions
- Parkinson's Disease, Obsessive Compulsive Disorder, Dystonia, Essential Tremor
- Trial name
- Brain Atlas (NCT00575081)
- Testing
- Stereotactic brain procedures
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Vanderbilt University Medical Center
Parkinson Disease, Dystonia
Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNS
The objective of this study is to compile real-world outcomes of Boston Scientific commercially approved radiofrequency (RF) ablation systems used in the central nervous system (CNS) for use in functional neurosurgery.
- Conditions
- Parkinson Disease, Dystonia, Essential Tremor, Movement Disorders
- Trial name
- NCT06553625
- Testing
- Radiofrequency Ablation
- Where
- 4 sites in Germany, United Kingdom
- Volunteers
- 200 people
- Sponsor
- Boston Scientific Corporation
Movement Disorders
Multimodal MR Imaging Study on ET and PD Patients Subjected With MRgFUS Thalamotomy
The technological advance of magnetic resonance-guided focused ultrasound (MRgFUS) has once again brought lesion therapy back to the clinical frontline for the treatment of movement disorder.
- Trial name
- NCT05623644
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Growth Disorders, Dietary Exposure
Evaluating the Effects of an Oral Protein Supplement on Children's Growth Patterns
This single-center, randomized controlled pilot study aims to evaluate the efficacy of TruHeight Growth Protein Shake on improving growth patterns in children aged 4-17 years.
- Conditions
- Growth Disorders, Dietary Exposure, Child Development, Bone Development Abnormal
- Trial name
- NCT06329388
- Testing
- TruHeight Growth Protein Shake
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- TruHeight Vitamins