Clinical trials: Tooth Plaque
Dental Plaque
Plaque Removal Efficacy of a U-Shaped Sonic Power Toothbrush in Children
The objective of this single-use, examiner blinded, randomized, two-period, cross-over, IRB-approved clinical study is to evaluate the safety and plaque removal efficacy of AutoBrush®, a new children's 360° sonic toothbrush…
- Trial name
- NCT06300073
- Testing
- Experimental: U-shaped Power Toothbrush
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Lander Enterprises, LLC
Healthy
The Effect of Portable AR on Tooth Brushing Skill for Elementary School Students
The aim of this study An augmented reality (AR) simulation toothbrushing machine was developed to train proper brushing technique for children.
- Trial name
- NCT05956262
- Testing
- AR-toothbrush machine, Teach proper brushing skills
- Where
- Taiwan
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pediatric Obesity, Periodontal Disease
Dental and Periodontal Health in Obese Adolescents: Clinical, Biochemical, and Microbiological Evaluation
This study aims to investigate whether obesity affects oral and gum health in children and adolescents. A total of 75 children aged 8 to 13 years participated, including both obese and non-obese individuals.
- Conditions
- Pediatric Obesity, Periodontal Disease, Inflammation Biomarkers, Dental Plaque
- Trial name
- PERIOBESITY (NCT07086027)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Marmara University
White Spot Lesion of Tooth, Long Term Adverse Effects
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures…
- Conditions
- White Spot Lesion of Tooth, Long Term Adverse Effects, Caries, Dental, Orthodontic Appliance Complication
- Trial name
- NCT03004196
- Testing
- Probiotic Toothpaste, Dr. Reddy's Clohex, Control Group
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peoples University, Bhanpur, Bhopal
Gingivitis
The Efficacy of Different Adjunctive Plaque Control Modalities in Orthodontic Patients
Bacterial plaque is the primary etiological factor for periodontal disease ranging from mild gingival inflammation to severe periodontitis.The fixed appliance can alter the microbial composition of the oral environment.Patients…
- Trial name
- NCT05889975
- Testing
- interdental brush, single tufted brush, water irrigator
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Oral Health, Knowledge
Effectiveness MyBRUSH Module in Improving Knowledge, Attitude, and Behaviour on Toothpaste Use and Toothbrushing Among 12-Year-Old Children
The goal of this intervention study is to study the effectiveness of the oral health education module (MyBRUSH) in improving the knowledge, attitude, and behaviour on toothpaste use and toothbrushing among 12-year-old children.
- Conditions
- Oral Health, Knowledge, Attitude, Behavior
- Trial name
- MyBRUSH module (NCT07125560)
- Testing
- MyBRUSH module, BEGIN program
- Where
- 8 sites in Malaysia
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Adolescent Behavior, Dental Plaque
Evaluating the Effectiveness of a Cognitive Behavioral Intervention (CBI)
This is a Phase III, randomized, one-center, three arm parallel group, open label and single blind clinical study to evaluate the effectiveness of a cognitive behavioral intervention (CBI) adjunctive to a smart powered toothbrush…
- Conditions
- Adolescent Behavior, Dental Plaque, Gingivitis, Cognitive Change
- Trial name
- NCT05782348
- Testing
- Cognitive behavioral intervention, Colgate smart toothbrush
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Howard University
Dental Caries, Dental Plaque Accumulation
Miswak (Salvadora Persica) Versus a Toothbrush in Plaque Removal
The study investigates the effectiveness of a 45°-cut miswak for plaque removal compared to a toothbrush in children and assesses their preferences for these tools.
- Trial name
- NCT07409610
- Testing
- Miswak, Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Evaluations, Diagnostic Self, Antimicrobial
ZnO Nanoparticles Coated Orthodontic Molar Tube
Orthodontic treatment is an elective procedure to improve the patient's dentofacial appearance. The complex design of fixed appliances provides a platform that leads to increased plaque accumulation around orthodontic brackets.
- Conditions
- Evaluations, Diagnostic Self, Antimicrobial, Orthodontic Appliance Complication, Bacterial Overgrowth
- Trial name
- ZnONPs (NCT06089720)
- Testing
- Zinc oxide nanoparticle coated orthodontic molar tubes (experimental), orthodontic molar tubes (control)
- Where
- Iraq
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Orthodontic Pain (D013850), Malocclusion
Comparison of Three Orthodontic Separators for Pain, Plaque, and Tooth Separation
Orthodontic separators are small devices placed between teeth before fitting braces to create space for bands. This procedure may cause pain, discomfort, and changes in oral hygiene, which can affect plaque buildup and daily…
- Conditions
- Orthodontic Pain (D013850), Malocclusion, Orthodontic Treatment
- Trial name
- SEP-ORTHO (NCT07532044)
- Testing
- Elastomeric Separator, Kesling Separator, Tie wire separator
- Where
- Pakistan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Islamabad Medical and Dental College
Specific Learning Disabilities, Dental Plaque
Plaque Removal Efficiency in Children With Specific Learning Disabilities
This study aims to evaluate the effectiveness of toothbrushing education on plaque removal in children aged 7-12 years with specific learning disabilities (SLD) and to compare their plaque removal performance with healthy…
- Conditions
- Specific Learning Disabilities, Dental Plaque, Oral Hygiene
- Trial name
- PRE-SLD (NCT07611942)
- Testing
- Standardized Toothbrushing Education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Plaque Induced Gingival Disease, Oral Health
Effect of Benzydamine Hydrochloride Mouthrinse on Plaque Accumulation in Periodontally Healthy Female Subjects
The goal of this clinical trial is to evaluate the effect of a mouthrinse containing an active ingredient benzydamine hydrochloride in the absence of daily oral hygiene.
- Trial name
- BHCl-PLAQUE (NCT07565766)
- Testing
- Benzydamine hydrochloride mouthrinse
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Plaque Removal
Comparison of New and 3-Month-Old Toothbrush in the Removal of Plaque in Children
This study aimed to validate or invalidate non-inferiority in the plaque removal efficacy of old versus new toothbrushes in the hands of 7-9 year old children.
- Trial name
- NCT00836784
- Testing
- old toothbrush, New tooth brush
- Where
- Iran
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Orthodontic Appliance Complication
The Effect of Different Remineralizing Agents on White Spot Lesions and Dental Plaque During Orthodontic Retention
Dental caries is a decay process that breaks down the tooth. The earliest clinical signs of active dental caries is seen as 'white spot lesions' (WSLs).
- Trial name
- NCT04788550
- Testing
- Fluoridated toothpaste, fluoride varnish (5% sodium fluoride), CPP-ACP plus crème group
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Autism Spectrum Disorder
Effectiveness of Picture Exchange Communication System on Gingival Health of Children With Autism Spectrum Disorders
The Picture Exchange Communication System (PECS) is a communication system for children with autism spectrum disorders (ASD). The aim of this study was to assess the effect of a PECS-based tooth-brushing program on gingival…
- Trial name
- NCT03791385
- Testing
- Picture Exchange Communication System (PECS)
- Where
- Jordan
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Oral Hygiene, Dental Plaque Induced Gingivitis
Mobile Phone Messaging To Improve Oral Hygiene Among Primary School Children in Pakistan
Oral health is an important component of general health and oral cavity acts as a mirror to the health of individuals and communities.
- Trial name
- NCT03390452
- Testing
- Mobile Phone Messaging
- Where
- 2 sites in Pakistan
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Health Services Academy, Islamabad, Pakistan
Dental Fluorosis, Dental Caries
Effect of pH and Fluoride Concentration of Dentifrices on Caries Control
This study aims to assess the overall effect of pH and fluoride concentration of liquid dentifrices in the control of children dental caries of a fluoridated area, through visual inspection and the quantitative light-induced…
- Trial name
- EPHFCDCC (NCT01049503)
- Testing
- Low fluoride and conventional dentifrices with different pH
- Where
- Brazil
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Plaque, Plaque, Dental
Evaluation of the Effectiveness of Different Toothbrushes in Children
Control groups will be formed in the 2-12 age group using standard manual toothbrushes, and the effectiveness of 360-degree bristle toothbrushes will be compared. Study design: Experimental study
- Conditions
- Dental Plaque, Plaque, Dental, Oral Hygiene, Gingivitis
- Trial name
- NCT06164496
- Testing
- standart manual toothbrush, 360 degree toothbrush
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Marmara University
Acne Vulgaris, Gingivitis
Association of Acne Vulgaris With Oral Hygiene and Gingivitis
The goal of this observational study is to learn about in the relationship between acne vulgaris and oral hygiene and gingivitis.
- Conditions
- Acne Vulgaris, Gingivitis, Dental Plaque, Oral Hygiene
- Trial name
- NCT06237387
- Testing
- Periodontal examination
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Orthodontic Treatment
Flash-free Brackets and Dental Plaque
This study aimed to compare flash-free bracket system with conventional adhesive-coated bracket system in patients with maxillary crowding.
- Trial name
- NCT03187483
- Testing
- orthodontic treatment
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ege University