Clinical trials: Tooth Abnormalities
Molar Incisor Hypomineralization, Anesthesia, Local
Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars
The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia…
- Trial name
- NCT05964387
- Testing
- SDF
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Molar Incisor Hypomineralization, Oral Health
Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization
Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL).
- Conditions
- Molar Incisor Hypomineralization, Oral Health, Child, Only, Pediatric ALL
- Trial name
- NCT05779332
- Testing
- survey application
- Where
- Turkey (Türkiye)
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Pit and Fissure Sealants, Molar Incisor Hypomineralization
Clinical Evaluation of Two Different Pit and Fissure Sealants
It is planned to include girls and boys between the ages of 6-12 who apply to Başkent University Faculty of Dentistry, Pediatric Dentistry Clinic for routine dental examination.
- Trial name
- NCT06776471
- Testing
- Resin-based flowable filling material
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Baskent University
Dental Caries Extending to Pulp, Molar Incisor Hypomineralization
Vital Pulp Therapy in Carious Teeth With Hypomineralization
Vital pulp therapy (VPT) is a general term for multiple procedures (indirect pulp cap, direct pulp cap and pulpotomy) all directed toward preserving pulp vitality and enable complete root development in immature teeth.
- Trial name
- NCT03735069
- Testing
- IPT (Indirect pulp treatment), Cvek/partial pulpotomy, Cervical pulpotomy
- Where
- Jordan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Children, Adult, Molar Incisor Hypomineralization
Effectiveness of Infiltration With Resin in Treatment of MIH Incisors in Children Showing Opacities
Enamel development defects are the result of a set of environmental, systemic and genetic causal agents that reveal a multifactorial etiology model, which in anterior teeth produces a serious aesthetic problem, converted into a…
- Conditions
- Children, Adult, Molar Incisor Hypomineralization, Dental Diseases, Opacity
- Trial name
- NCT05597956
- Testing
- white defects, yellow defects, brown defects
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- University of Valencia
Molar Incisor Hypomineralization
Effects of Different Remineralization Agents on Molar Incisor Hypomineralization Defects: a Randomized Clinical Study
The aim of this study was to present a comparative evaluation of the long-term efficacy of fluoride varnish( Flúor protector), Clinpro™ White Varnish and pastes containing CPP-ACP in the remineralization of creamy-white and…
- Trial name
- NCT06362681
- Testing
- Fluoride
- Where
- Mexico
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Oral Mucosal Disease
Clinical Research Core Dental Screening Protocol
This study will screen patients for eligibility in studies sponsored by the Craniofacial Genetics Section (HCGS), the Clinical Research Core (CRC), and other branches located within the National Institute of Dental and…
- Trial name
- NCT00090818
- Where
- United States
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Short Stature, Hypomineralization Molar Incisor
Hypo-mineralization of Primary and Permanent Teeth in a Group of Children With Stunted Growth.A Cross Sectional Study.
The second primary molar (SPM) development start at the same time as development of the first permanent molars (FPM) and permanent incisors so any systemic disturbance - causing stunted growth -occur , will result in…
- Conditions
- Short Stature, Hypomineralization Molar Incisor, Hypomineralization of Enamel
- Trial name
- NCT04774653
- Testing
- No intervention
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Molar-Incisor Hypomineralization (MIH)
Er:YAG Laser Versus Conventional Cavity Preparation in Children With Molar-Incisor Hypomineralization
This randomized clinical trial compares Er:YAG laser-assisted and conventional rotary cavity preparation in children aged 6-12 years with molar-incisor hypomineralization.
- Trial name
- NCT07759739
- Testing
- Er:YAG Laser-Assisted Cavity Preparation, Conventional Rotary Cavity Preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Ege University
Molar-Incisor Hypomineralization
Clinical Efficacies of Different Agents in Molar-Incisor Hypomineralization
This study aims to assess the clinical effectiveness of GC Fuji Triage ® (GC America Inc., Alsip, Illinois) and BeutiSealant (Shofu, Kyoto, Japan) in children aged 8-13 with multiple molars affected by Molar-Incisor…
- Trial name
- NCT06180369
- Testing
- GC Fuji Triage ® GC America Inc., Alsip, Illinois ), BeutiSealant (Shofu, Kyoto, Japonya)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Fluorosis
Presence of Enamel Fluorosis in Libyan Children
Fluorosis is caused by hypomineralization in the enamel due to increased fluoride ingestion during early childhood (Cawson.1, Wong et al. 2, and Sudhir 3).
- Trial name
- NCT03746990
- Volunteers
- 1,935 people, healthy volunteers welcome
- Sponsor
- Ajman University
Charcot-Marie-Tooth Disease, Type Ia
High Dose Ascorbic Acid Treatment of CMT1A
This study will look at the impact of ascorbic acid (Vitamin C) on the progression of disease in people with CMT1A as compared to volunteers receiving a placebo.
- Trial name
- NCT00484510
- Testing
- Ascorbic acid (Vitamin C)
- Where
- 3 sites in United States
- Volunteers
- 110 people
- Sponsor
- Wayne State University
Anomaly
Prevalence of Dental Anomalies in Oral Clefts Patients
To assess the prevalence of dental anomalies in the deciduous dentition in children with oral clefts and to investigate the associated risk factors.
- Trial name
- NCT05304260
- Testing
- clinical and radiographic examination
- Volunteers
- 93 people
- Sponsor
- Cairo University
Molar-Incisor Hypomineralization, Peridontal Disease
Molar-Incisor Hypomineralization Vs Periodontal Health
Background: To investigate the effect of molar incisor hypomineralization (MIH) on periodontal health, to evaluate the relationship between gingival crevicular fluid (GCF) volume, and GCF biomarkers such as matrix…
- Trial name
- MIH (NCT06764043)
- Testing
- Clinical evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Hypomineralization Molar Incisor
Photobiomodulation and Glass Ionomer Sealant as Complementary Treatment for Hypersensitivity in Molars With MIH
Introduction: Photobiomodulation (PBM) shows promising results for the complementary treatment of dentin hypersensitivity; however, few studies have evaluated this treatment specifically for teeth affected by molar incisor…
- Trial name
- NCT05370417
- Testing
- Use of fluoride toothpaste, Photobiomodulation, Simulated Laser Therapy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Molar Incisor Hypomineralisation
Local Anesthesia With Lidocaine or Articaine for Molars Affected by MIH
Aims: Comparison of injection pain with lidocaine and articaine in children with MIH . Comparison of the efficacy of lidocaine and articaine during treatment of MIH molars.
- Trial name
- NCT05200884
- Testing
- Lidocaine 2%, Articaine 4%
- Where
- Syria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Latakia University
Charcot-Marie-Tooth Disease, Hereditary Motor and Sensory Neuropathy IV
A Natural History Study of Charcot-Marie-Tooth 4J (CMT4J)
Charcot-Marie-Tooth 4J (CMT4J) is a rare inherited peripheral neuropathy often characterized by rapidly progressive, asymmetrical upper and lower extremity weakness, muscle atrophy leading to loss of ambulation, respiratory…
- Trial name
- CMT4J (NCT03810508)
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Neurogene Inc.
Hypodontia
Frequency of Hypodontia After Chemotherapy in Childhood Cancer Survivors Study
This study aims to provide information on the frequency of hypodontia in children cancer survivors receiving chemotherapy before 4 years of age.Patients who met the eligibility criteria will be given a structured questionnaire to…
- Trial name
- NCT03445026
- Testing
- dental panorama
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Effect of Enamel Cleaning on a Remineralizing Paste for Hypomineralizated Lesions
Molar-incisor hypomineralization (MIH) is a qualitative defect of dental enamel, in which low mineral content and high protein content compromise the effectiveness of remineralizing treatments.
- Trial name
- ECLIPSE (NCT07653373)
- Testing
- Sodium hypochlorite 5.25%, CPP-ACPF
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidade Ceuma
Tooth Agenesis
Craniofacial Morphology And Sella Turcica Bridging Associated With Third Molar Agenesis.
The aim of this retrospective study is to analyze the third molar agenesis with respect to sella turcica bridging and other craniofacial patterns in patients asking for orthodontic consultation.
- Trial name
- NCT05771246
- Testing
- Radiographic evaluation
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University of Pavia