Clinical trials: Tooth
Anomaly
Prevalence of Dental Anomalies in Oral Clefts Patients
To assess the prevalence of dental anomalies in the deciduous dentition in children with oral clefts and to investigate the associated risk factors.
- Trial name
- NCT05304260
- Testing
- clinical and radiographic examination
- Volunteers
- 93 people
- Sponsor
- Cairo University
Crowding, Tooth, Orthodontic
Orthodontic Treatment in Adolescents With Crowding and Displaced Teeth
The purpose is to fill knowledge gaps identified for orthodontic treatment using a novel study design that has not been implemented in the dental field or in orthodontics.
- Trial name
- CROWDIT (NCT05664282)
- Testing
- Damon self-ligating brackets, Victory self-ligating brackets
- Volunteers
- 131 people
- Sponsor
- Malmö University
Dental Caries, Streptococcus Mutans
Effect of MI Paste Plus™ on Streptococcus Mutans and White Spot Lesions in Fixed Orthodontics
Background This study is part of a doctoral research project at Universidad Cardenal Herrera CEU (Spain), directed by Prof. Santiago Arias de Luxán and conducted by doctoral candidate Shirli Kelmendi within the PhD program in…
- Conditions
- Dental Caries, Streptococcus Mutans, Tooth Demineralization, Orthodontic Appliances, Fixed
- Trial name
- MIPASTEORTHO (NCT07244991)
- Testing
- MI Paste Plus (CPP-ACP with Sodium Fluoride)
- Where
- 2 sites in Albania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Pain, Teeth, Impacted
Evaluation of Articaine 4% Versus Mepivacaine 2% for Surgery of Molars Thirds: Clinical Trial.
The extraction of third molars, a frequent treatment in clinical dental practice, can lead patients to painful symptoms during and after surgery.
- Trial name
- NCT03384160
- Testing
- Group 1 -Pain monitor, Group 2 -Pain monitor
- Where
- Brazil
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Molar Hypomineralization
Intraosseus Injection Using Extra-short Needle Combined With Infiltration in Pediatric Patients With Molar Incisor Hypomineralization
Background: Effective pain control is crucial in managing pediatric dental patients. Molar-incisor hypomineralization (MIH), marked by enamel defects and dentin hypersensitivity, often hinders effective local anesthesia.
- Trial name
- NCT07239050
- Testing
- intraosseus anesthesia, Conventional nerve block
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Child Behavior
Parent Predicting of Their Child Behavior During Their First Dental Examination
The aim of this study is to assess the parental expectation for their child behavior in a group of children with primary dentition during their first dental examination
- Trial name
- NCT04307810
- Volunteers
- 170 people
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Molar Incisor Hypomineralization and Hypomineralized Second Primary Molars
Molar and Incisor Hypomineralization (MIH) is a qualitative developmental defect of the dental enamel with a multifactorial aetiology defined in 2001 as an "hypomineralization of systemic origin affecting one or more permanent…
- Trial name
- NCT05809791
- Where
- 5 sites in Italy, Spain and 1 more
- Volunteers
- 97 people
- Sponsor
- IRCCS Burlo Garofolo
Obesity, Childhood, Orthodontic Treatment
Evaluation of the Effects of Obesity on Orthodontic Tooth Movement
In this study, bone remodeling in the gingival crevicular fluid was evaluated biochemically during canine distalization in obese individuals and compared with normal weight individuals.
- Trial name
- NCT05988723
- Testing
- ELISA kits
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Angle Class II
Maxillary Molar Distalization Supported by Mini-implants With the Advanced Molar Distalization Appliance (Amda®)
The aim of this randomized controlled clinical trial is to evaluate the dentoalveolar and skeletal treatment effects of the AMDA when used for distalization of the maxillary first molars in patients with Class II malocclusion in…
- Trial name
- NCT06011382
- Testing
- Advanced Molar Distalization Appliance (amda®), Buccal mini-implants
- Where
- Romania
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Traumatic Pulp Exposure in Children
Clinical And Radiographic Evaluation Of Nano-Propolis, Nano-Curcumin and MTA as Direct Pulp Capping Agents in Young Permanant Teeth
The aim of the study is to evaluate clinical and radiographic effect of nano propolis and nano curcumin as direct pulp capping agents in young permanent teeth. .
- Trial name
- NCT06029023
- Testing
- MTA Cement, propolis nano particle, curcumin nanoparticles
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Plaque
Evaluation of Toothpaste on Dental Plaque
The aim of this study is to compare the plaque reduction efficacy of toothpaste to a marketed active magnesium toothpaste with single-use brushing in children.Our study will consist of 50 people between the ages of 9-12.
- Trial name
- NCT05868590
- Testing
- Toothpaste
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Tooth Movement Techniques, Distalization by Miniscrews
Evaluation of Three-Dimensional Printed Orthodontic Molar Distalizer
A randomized clinical trial to evaluate a newly designed 3D printed miniscrew-supported molar distalization device in comparison to the conventional miniscrew-supported distal jet appliance in correction of Class II malocclusion…
- Trial name
- RCT (NCT07191158)
- Testing
- Group 1 conventional, Group 2 3D printed
- Where
- Iraq
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Caries, Oral Health Behavior Change
Assessing the Impact of a Social Media-Based Educational Intervention Using WhatsApp Video Messages on Dental Caries Prevention Knowledge, Oral Hygiene Practices, and Attitudes Toward Dental Health Among Primary School Children Aged 10-12 Years in Public Schools in Cairo Governorate, Egypt: A Quasi-
The goal of this study is to learn if educational videos sent through WhatsApp can improve dental health knowledge, healthy habits, and attitudes in primary school children aged 10 to 12 years in Cairo, Egypt.
- Conditions
- Dental Caries, Oral Health Behavior Change, Oral Hygiene, Oral Health, Knowledge, Attitudes, Practice
- Trial name
- NCT07363317
- Testing
- WhatsApp-Based Dental Health Education for Children
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rana Mohamed Ahmed Farghal
Dental Caries
Prevention of Enamel Demineralization by Use of K18-smooth Surface Sealant
This study will evaluate effectiveness of a urethane dimethacrylate (UDMA)-quaternary ammonium methacrylate (K18) resin (UDMA-K18) smooth surface sealant to prevent biofilm attachment to tooth surfaces thereby eliminating the…
- Trial name
- K18 (NCT03306433)
- Testing
- UDMA-K18 smooth surface sealant
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Vitamin D3 Deficiency, Prematurity
Vitamin D and Health Outcomes in Preterm Born Population
Improved survival of very preterm newborn population during the last decades has challenged us neonatologists to study and improve nutritional practices including vitamin D (VitD) supplementation.
- Conditions
- Vitamin D3 Deficiency, Prematurity, Lung Diseases, Heart Rate Variability
- Trial name
- ViDePrePop (NCT04342078)
- Testing
- Vitamin D
- Where
- Finland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Dental Trauma
Factors Affecting the Pulpal Prognosis of Injured Teeth
Factors affecting the pulpal prognosis of injured teeth. Dental injuries may affect the survival of teeth. It is recommended to monitor the injured teeth at regular intervals to ensure that the appropriate treatment is delivered…
- Trial name
- TRAUMA (NCT03845426)
- Testing
- Root canal treatment.
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Molar Incisor Hypomineralisation
Local Anesthesia With Lidocaine or Articaine for Molars Affected by MIH
Aims: Comparison of injection pain with lidocaine and articaine in children with MIH . Comparison of the efficacy of lidocaine and articaine during treatment of MIH molars.
- Trial name
- NCT05200884
- Testing
- Lidocaine 2%, Articaine 4%
- Where
- Syria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Latakia University
Tooth Loss
Clinical Evaluation of Bonded Versus Banded Space Maintainers
Comparing bonded space maintainers to banded space maintainers
- Trial name
- NCT05087147
- Testing
- 0.7 mm stainless steel orthodontic wire, Banded space maintainer
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Omar Sherif Ahmed Abo El Abbas
Charcot-Marie-Tooth Disease
Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients
The study will consist of 2 periods: Double-blind Treatment and Open-Label Extension(OLE) Period. -Double-blind Treatment Period - This will be randomized, double-blind, placebo-controlled part of the study which will be…
- Trial name
- PREMIER (NCT04762758)
- Testing
- (RS)-baclofen, naltrexone hydrochloride and D-sorbitol
- Where
- 50 sites in United States, Belgium and 7 more
- Volunteers
- 350 people
- Sponsor
- Pharnext S.C.A.
CMT 1A
Driving Ability in Patients With CMT 1A
Charcot Marie Tooth 1A (CMT 1A) is a common inherited disorder of the nerves in the body. The disease can result in difficulties with strength and balance as well as in foot deformities such as high arches, hammer toes, and tight…
- Trial name
- NCT02357355
- Testing
- UIHC Driving Simulator
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Jerath U Nivedita
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