Clinical trials: TMS
Healthy, Healthy Volunteer
Effect of Transcranial Magnetic Stimulation on Memory
This study will examine the effect of transcranial magnetic stimulation (TMS) on short-term memory in healthy adults. Healthy people use their brains to answer short-term memory questions in a different way than do patients with…
- Conditions
- Healthy, Healthy Volunteer, HV
- Trial name
- NCT00105118
- Testing
- Magstim Super Rapid Magnetic Stimulator
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Spectrum Disorder, Intellectual Disability
Transcranial Magnetic Stimulation Studies in Autism Spectrum Disorders
Autism Spectrum Disorder (ASD) is the most prevalent of the developmental disorders and their incidence is rising. However, the variability in the behavioral symptoms is large.
- Trial name
- NCT02591446
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Major Depressive Disorder
Safety and Effectiveness of NeuroStar® Transcranial Magnetic Stimulation (TMS) Therapy in Depressed Adolescents
To evaluate the safety and efficacy of daily, active Neurostar® TMS (when compared with sham treatment) in adolescents meeting criteria for Major Depressive Disorder (MDD).
- Trial name
- NCT02586688
- Testing
- Active NeuroStar® Transcranial Magnetic Stimulation (TMS)
- Where
- 13 sites in United States
- Volunteers
- 112 people
- Sponsor
- Neuronetics
Autism Spectrum Disorder, Autism
Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD
Investigating the efficacy of a form of TMS called theta-burst stimulation for restricted and repetitive behavior in ASD.
- Conditions
- Autism Spectrum Disorder, Autism, Asperger Syndrome
- Trial name
- TMS for ASD (NCT04532424)
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Stanford University
Impaired Insight
Targeted Intervention Study of DTMS on Impaired Insight in Early Psychosis
Impaired insight is a key factor in the conversion of high-risk individuals to schizophrenia, but there is a lack of targeted interventions.
- Trial name
- NCT04513132
- Testing
- active-dTMS
- Where
- China
- Sponsor
- Shanghai Mental Health Center
Alzheimer Disease, Mild Cognitive Impairment
Transcranial Magnetic Stimulation in Mild Cognitive Impairment and Alzheimer Disease
The investigators reviewed 12 years of clinical use in an outpatient neurology setting of transcranial magnetic stimulation (TMS) in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) to evaluate safety…
- Trial name
- NCT04771845
- Testing
- Transcranial Magnetic Stimulation
- Volunteers
- 73 people
- Sponsor
- The New York Memory Services
Major Depressive Disorder
NeuroStar TMS Therapy System: Utilization and Outcomes
The major objective of this observational study is to describe clinical outcomes of patients receiving treatment with the NeuroStar TMS Therapy system in routine clinical practice.
- Trial name
- NCT01114477
- Where
- 44 sites in United States
- Volunteers
- 307 people
- Sponsor
- Neuronetics
Autism Spectrum Disorder, Intellectual Disability
TMS for the Investigation of Brain Plasticity in Autism Spectrum Disorders
The main purpose is to study brain plasticity (the changes that occur in the brain through experience) in individuals with autism spectrum disorder (ASD).
- Trial name
- NCT02836405
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Cerebral Palsy, Typically Developing Children
Repetitive Transcranial Magnetic Stimulation on Motor Function and Meta-Plasticity in Cerebral Palsy: TMS-EEG Study
This project examines the use of repetitive transcranial magnetic stimulation (rTMS) as a therapeutic approach to improve motor function in children with cerebral palsy (CP).
- Trial name
- NCT07567053
- Testing
- MRI, HD-EEG Recording, rTMS
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cook Children's Health Care System
Neurofibromatosis 1
Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1
Children with neurofibromatosis type 1 (NF1) commonly suffer from the effects of cognitive, behavioral, and motor impairments. At present, there is no specific treatment for this NF1 complication.
- Trial name
- DoDNAC (NCT04481048)
- Testing
- N-Acetyl cysteine
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder
Abnormal Connectivity Involving the Social Reciprocity Network in Autism and the Impact of Neurostimulation in Mitigating the Abnormalities
There is no consensus regarding the neurological substrate underpinning ASD. The investigators describe the novel concept of "social reciprocity network" and hypothesize that aberrant connectivity/oscillatory patterns affecting…
- Trial name
- NCT06807684
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Christiana Care Health Services
ASD, Autism Spectrum Disorder
Theta Burst Stimulation for Refractory Depression in Autism Spectrum Disorder
Evaluate the efficacy of accelerated theta burst stimulation (aTBS) in reducing depressive symptoms in autism spectrum disorder (ASD)
- Conditions
- ASD, Autism Spectrum Disorder, Autism, Depression - Major Depressive Disorder
- Trial name
- RETSORE-RCT (NCT06670040)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Spinal Cord Injury Cervical, Spinal Cord Injury, Acute
Upper Limb Rehabilitation Using Non-invasive Spinal Cord Stimulation
The goal of this RCT study is to evaluate if combining activity-based therapy (ABT) with transcutaneous spinal cord stimulation (tSCS) can improve recovery of arm and hand movement in people with cervical spinal cord injury…
- Conditions
- Spinal Cord Injury Cervical, Spinal Cord Injury, Acute, Spinal Cord Injury (Quadraplegia)
- Trial name
- CIME_upperlimb (NCT07361627)
- Testing
- Protocol 2: Combination of activity-based therapy and facilitatory transcutaneous spinal cord stimulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Tourette Syndrome
Multi-site Transcranial Magnetic Stimulation Therapy of the Supplementary Motor Area in Children With Tourette Syndrome
The investigators are investigating the effectiveness of a wearable multisite transcranial magnetic stimulation (mTMS) device that can deliver stimuli at multiple cortical sites simultaneously or sequentially for the treatment of…
- Trial name
- NCT03642951
- Testing
- Active Treatment
- Where
- United States
- Sponsor
- Children's Mercy Hospital Kansas City
Borderline Personality Disorder
rTMS-enhanced Psychotherapy for Borderline Personality Disorder
This project assesses the effectiveness and lasting impact of combining Dialectical Behavioral Therapy (DBT) with prefrontal repetitive transcranial magnetic stimulation (rTMS) in patients with borderline personality disorder.
- Trial name
- rTMS-DBT (NCT06259851)
- Testing
- Dialectical behavioral therapy program, Prefrontal rTMS treatment
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Masarykova Univerzita
Chronic Pain, Depression
Repetitive Transcranial Magnetic Stimulation and Acceptance and Commitment Therapy
Veterans with comorbid chronic pain and depression are highly prevalent, have poor functional status and low quality of life, are at increased risk of suicide and lack access to effective treatments.
- Trial name
- NCT05427201
- Testing
- Repetitive Transcranial Magnetic Stimulation, Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- VA Office of Research and Development
Blindness
Brain Plasticity of Verbal Memory in the Blind
This study will examine whether blind people develop changes in the brain that improve memory function. Previous studies have shown that blind people, on average, perform better in memory tasks than sighted people.
- Trial name
- NCT00059189
- Testing
- Magstim Rapid Magnetic Stimulator
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Pneumonia, Pneumocystis Carinii, HIV Infections
A Randomized, Comparative, Prospective Study of Daily Trimethoprim / Sulfamethoxazole (TMS) and Thrice-Weekly TMS for Prophylaxis Against PCP in HIV-Infected Patients
To compare the safety and efficacy of two dosage regimens (daily and thrice-weekly) of sulfamethoxazole/trimethoprim (SMX/TMP; TMS) in the prevention of Pneumocystis carinii pneumonia (PCP) in high-risk HIV-infected patients.
- Trial name
- NCT00000748
- Testing
- Sulfamethoxazole-Trimethoprim
- Where
- 24 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
West Syndrome
Cortical Excitability in West Syndrome Using Transcranial Magnetic Stimulation
Currently, no literature is available regarding degree of cortical excitability and its correlation with various epileptic syndromes and disorders such as West Syndrome in pediatric age group.
- Trial name
- NCT06201897
- Testing
- ACTH/Oral Steroids
- Where
- India
- Volunteers
- 40 people
- Sponsor
- All India Institute of Medical Sciences
Healthy
Effect of Transcranial Magnetic Stimulation on Free Will
This study will use transcranial magnetic stimulation (TMS) to investigate how the brain controls movement by sending messages to the spinal cord and muscles.
- Trial name
- NCT00029653
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)