Clinical trials: TBI-Traumatic Brain Injury
Insomnia, Traumatic Brain Injury
Non-Pharmacological Treatments for Insomnia in Chronic Traumatic Brain Injury
The purpose of this clinical trial is to assess the relative efficacy of two non-pharmacological interventions for insomnia in Veterans suffering from chronic mild traumatic brain injury (mTBI).
- Trial name
- NCT03261674
- Testing
- CBT-I, ABT-I
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury
Transforming Research and Clinical Knowledge in Traumatic Brain Injury
The overall goal of Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) study is to determine the relationships among the clinical, neuroimaging, cognitive, genetic and proteomic biomarker…
- Trial name
- TRACK-TBI (NCT02119182)
- Testing
- In-Person Outcome Assessment, Phone Outcome Assessment, 3T Magnetic Resonance Imaging (MRI)
- Where
- 23 sites in United States
- Volunteers
- 2,996 people
- Sponsor
- University of California, San Francisco
Patients in Minimally Conscious State After a Severe Brain Injury
tDCS on Precuneus in MCS: Repeated Stimulations
In this study researchers will apply transcranial direct current stimulation (tDCS) for 5 consecutive days in chronic patients in minimally conscious state (MCS).
- Trial name
- NCT02702362
- Testing
- transcranial direct current stimulation
- Volunteers
- 33 people
- Sponsor
- Hangzhou Normal University
Mild Traumatic Brain Injury
Pro-2-Cool Device Clinical Study
This study is being conducted to quantify the clinical safety and efficacy of head and neck cooling when applied up to 8 days after mild traumatic brain injury (mTBI) among adolescents participating in sporting activities.
- Trial name
- NCT03511339
- Testing
- TecTraum device
- Where
- 5 sites in United States
- Volunteers
- 174 people
- Sponsor
- TecTraum Inc.
Traumatic Brain Injury, Children
Intranasal Dexmedetomidine Sedation for Pediatric CT Imaging
This study has the objective to determine if intranasal dexmedetomidine, a sedative, is suitable for pediatric sedation in children undergoing tomographic scans.
- Trial name
- NCT01900405
- Testing
- Dexmedetomidine
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Post Traumatic Induced Spasticity
Selective Dorsal Rhizotomy as a Cost Effective and Safe Procedure as a Alternative to Intrathecal Baclofen Pump in Patients With Post Traumatic Spasticity
The investigators will investigate the selective dorsal rhizotomy in post traumatic brain and spinal cord injury induced spasticity to evaluate the efficacy of this procedure in reducing the tone of the spastic muscle groups.
- Trial name
- NCT07583277
- Testing
- Selective dorsal rhizotomy with neuromonitoring
- Volunteers
- 32 people
- Sponsor
- Assiut University
Traumatic Brain Injury
Rehabilitation Research and Training Center for Traumatic Brain Injury Interventions--Teen Online Problem Solving Study
This study will evaluate the effectiveness of an Internet-based psychosocial treatment in improving problem-solving, communication skills, stress management strategies, and coping among teens who have had a traumatic brain injury…
- Trial name
- RRTC--TOPS (NCT01042899)
- Testing
- Teen Online Problem Solving (TOPS), Teen Online Problem Solving--Teen Only (TOPS-TO), Internet Resources Comparison (IRC)
- Where
- 5 sites in United States
- Volunteers
- 153 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Brain Damage, Cerebral Palsy
Efficacy of Modified Constraint-induced Movement Therapy in Children With Brain Damage
This research centers on the comparison of the immediate efficacy (right after therapy) and the maintained efficacy (3 months and 6 months) between "Modified Constraint-Induced Movement Therapy" (mCIMT) group and control group at…
- Conditions
- Brain Damage, Cerebral Palsy, Traumatic Brain Damage
- Trial name
- NCT01076257
- Testing
- Modified Constraint-induced Movement Therapy
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Chang Gung Memorial Hospital
Concussion, Brain
Reduction of Concussion Symptoms Through the Use of Osteopathic Manipulative Therapy
Concussion incidence in high school and collegiate sports is high, especially in football. Once diagnosed, return to play is dependent on recovery from symptoms followed by a specific protocol for clearance; the sooner the…
- Trial name
- NCT04063618
- Testing
- Osteopathic Manipulative Therapy, Standard of Care Concussion Treatment
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Matthew T. Mcelroy, DO
Traumatic Brain Injury
A TMU/NIH Integrated Research Project Translation of Basic Research to Clinical Diagnosis and Treatment of Mild Traumatic Brain Injury (mTBI)
This integrated research project is cooperated by an fully-experienced team of Taipei Medical University and National Institutes of Health.
- Trial name
- NCT01266356
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- Taipei Medical University WanFang Hospital
Sport-related Concussion
Concussion Screen Use Recovery Time
A two-year parallel randomized clinical trial study to examine the effect of screen time (ST) restriction, exercise alone, and combined ST-restricted-exercise when compared to stretching only (control group) on sports related…
- Trial name
- NCT05373992
- Testing
- Screen Time Restriction (ST-Restricted), Aerobic Exercise (AE), Screen-time restricted plus aerobic exercise (STR+AE)
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Children's Health
Traumatic Brain Injury
Virtual Reality in Rehabilitation of Executive Functions in Children With Mild or Moderate Traumatic Brain Injury
Traumatic brain injury (TBI) causes lifelong disability. Children with TBI often have difficulties in attention regulation and executive functions affecting their daily living.
- Trial name
- VREALFUN-TBI (NCT06127459)
- Testing
- Parental Guidance, Virtual Reality Game
- Where
- Finland
- Volunteers
- 44 people
- Sponsor
- Merja Nikula
Traumatic Brain Injury
Effects of Hypothermia Upon Outcomes After Acute Traumatic Brain Injury
Induction of hypothermia to < 35˚C by < 2.5 hours after severe traumatic brain injury, reaching 33˚C by 4 hours after injury and maintained for 48 hours in patients aged 16-45 will result in an increased number of patients with…
- Trial name
- NABIS:HIIR (NCT00178711)
- Testing
- Hypothermia
- Where
- 5 sites in United States, Canada
- Volunteers
- 232 people
- Sponsor
- The University of Texas Health Science Center, Houston
Traumatic Brain Injury
Assessment of Noninvasive Neuromodulation in a Group of Traumatic Brain Injured Patients and Healthy Volunteers
Background: Severe traumatic brain injury, particularly diffuse axonal injury (DAI), often leads to lasting neurological issues.
- Trial name
- NCT07373366
- Testing
- Subjects in the intervention group receive low-frequency radioelectric therapy
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
MTBI - Mild Traumatic Brain Injury, Concussion, Mild
Evaluation of Helmet Technology and Head Impact Exposure
The purpose of the study is to monitor longitudinal changes in brain structure and function between the preseason and postseason, in a population of football playing athletes grouped by helmet make and model.
- Trial name
- NCT03883451
- Testing
- Helmet Model
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Brain Injuries
Telephone Intervention After Traumatic Brain Injury
This study seeks to determine if telephone counseling improves the outcome for persons with moderate to severe traumatic brain injury (TBI).
- Trial name
- NCT00483522
- Testing
- Self-management telephone counseling
- Where
- 3 sites in United States
- Volunteers
- 433 people
- Sponsor
- University of Washington
Brain Concussion
LED Therapy for the Treatment of Concussive Brain Injury
A double blind randomized trial of light-emitting diode (LED) therapy for patients suffering from mild traumatic brain injury (mTBI).
- Trial name
- NCT02383472
- Testing
- MedX Health Console model 1100
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Stroke, Cerebral Palsy
Functional Engagement in Assisted Therapy Through Exercise Robotics
The investigators have assembled an integrated knowledge/technology/client team to develop a novel motion capture-based home therapy program for children with hemiparesis (cerebral palsy, acquired brain injury (ABI)) and older…
- Conditions
- Stroke, Cerebral Palsy, Traumatic Brain Injury
- Trial name
- FEATHERS (NCT02290353)
- Testing
- FEATHERS
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of British Columbia
Concussion, Brain, Musculoskeletal Pain
The Impact of Eye and Body Training on the Injury Rate of Concussions in Female Soccer Players
The research project aims to find out how special training influences the frequency and severity of injuries among female footballers in the top Swiss league.
- Trial name
- NCT06473883
- Testing
- Training recommendation
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- BrainCare Medical Group
Stroke, Incomplete Spinal Cord Injury
Comparing the Ceriter Stride One, a Pressure-sensitive Smart Insole, With Gait Parameters Measured on the GRAIL in Neurological Populations
Ceriter Stride-One soles have been available on the market for several years. One of the features of these soles is that they can measure gait parameters while patients walk around in a functional environment.
- Conditions
- Stroke, Incomplete Spinal Cord Injury, Traumatic Brain Injury, Acquired Brain Injury
- Trial name
- NCT07237386
- Testing
- Wearing smart insoles
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent