Clinical trials: Surgery Scheduled
Atelectasis
Lung Recruitment Assessment With Lung Ultrasound In Pediatric Patient Scheduled For Laparoscopic Surgery
Anesthesia-induced atelectasis is a well-known entity observed in approximately 68-100% of pediatric patients undergoing general anesthesia.
- Trial name
- NCT02824146
- Testing
- Lung recruitment maneuver
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Glaucoma Patients Scheduled for Trabeculectomy
Comparison of Two Method Antimetabolites Application on Corneal Function in Trabeculectomy Surgery
Application of antimetabolite agents such as mitomycin_c has improved trabeculectomy results and better control of intraocular pressure complications such as corneal endothelial cell loss.
- Trial name
- NCT01297803
- Testing
- Mitomycin_c
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Anesthesia, Sedation
The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes
Perioperative fasting has historically been viewed as a low-risk intervention. However, preliminary data indicate that perioperative loss of nutrition and fluids is likely harmful.
- Conditions
- Anesthesia, Sedation, Monitored Anesthesia Care, Procedure
- Trial name
- MACS (NCT07022951)
- Testing
- Preoperative fasting
- Where
- United States
- Volunteers
- 1,200,000 people
- Sponsor
- Massachusetts General Hospital
Preoperative Care, Child
Reducing Anxiety of Children and Their Parents in the Pre-elective Surgery Process
It is emphasized in the studies that the child and parent anxiety that occurs in pediatric surgery should be prevented or reduced.
- Conditions
- Preoperative Care, Child, Parent, Anxiety
- Trial name
- NCT05538039
- Testing
- Distract with play dough, Distract with play kaleidoscope, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Isparta University of Applied Sciences
Liver Diseases
TachoSil Paediatric Liver Trial (TC-019-IN)
The overall objective is to assess the haemostatic efficacy and safety of TachoSil for control of local bleeding in paediatric patients undergoing surgical resection of the liver with our without segmental liver transplantation.
- Trial name
- NCT00365248
- Testing
- Fibrinogen human (TachoSil)
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Nycomed
Anemia
Non-invasive Identification of Preoperative Anaemia
Approximately 20% of patients undergoing elective orthopaedic surgery are anaemic. When not identified and treated before surgery, this can lead to requiring blood transfusions, which brings additional expenses, time and…
- Trial name
- NIPPA (NCT04247178)
- Where
- United Kingdom
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Surgery, Blood Loss
Epidemiology of Severe Peroperative Bleeding During Scheduled Surgery
Peroperative bleeding has been studied in specific populations exposed to bleeding (i.e. cardiac surgery, orthopedic surgery). Epidemiology of peroperative bleeding and transfusion remain poorly studied in the whole cohort of…
- Trial name
- NCT02311309
- Testing
- Control, Unanticipated bleeding
- Volunteers
- 1,439 people
- Sponsor
- University Hospital, Caen
Loosening, Prosthesis, Hip Arthropathy
Radiographic Stability of Hip Prosthesis Prior to Revision Surgery
The goal of this validation study is to compare the preoperative implant stability, assessed by Implant Movement Analysis (IMA), provocation dual CT scans, with the intraoperative stability evaluation in revision hip arthoplasty.
- Trial name
- MULTICIMA (NCT06924567)
- Testing
- Implant motion provocation CT
- Where
- 6 sites in Denmark, Norway and 1 more
- Volunteers
- 600 people
- Sponsor
- Georgios Tsikandylakis, MD PhD
Patients With Coronary Artery Disease Scheduled for by Pass Surgery
Atrial Fibrillation and By-pass Surgery
The aim of the study is to evaluate whether combined therapy with beta-blocker, amiodarone and statine is better than beta-blocker alone for the prevention of atrial fibrillation after coronary by-pass surgery.
- Trial name
- NCT01955759
- Testing
- Amiodarone tab 200 mg x 3, rosuvastatin 20 mg tab x1, beta blockers Bisoprolol in adjusted dose
- Where
- Bosnia and Herzegovina
- Volunteers
- 260 people
- Sponsor
- Heart Center BH Tuzla
Circumcision, Adolescents
Safety and Efficacy Study of Non-Surgical MC Device for Adolescent Male Population Including Contraindicated Subjects
A new Male Circumcision (MC) device, PrePex, has shown great promise as a way to radically shift the MC landscape. PrePex is an innovative circumcision device requiring no injected anesthesia, sutures, or sterile settings.
- Trial name
- NCT02581722
- Testing
- PrePex Device
- Where
- Rwanda
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
Scoliosis
Accuracy of Pleth Variability Index (PVI) in Children
Plethysmographic Variability index is a simple index accurate in predicting fluid responsiveness. The aim of this study was to investigate its accuracy in predicting fluid response to intravenous fluid challenge during scoliosis…
- Trial name
- PVI (NCT01820845)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anemia
A Study to Evaluate the Safety of Epoetin Alfa and Its Effectiveness in Facilitating the Presurgical Collection of Blood From Anemic Patients for Possible Self-transfusion During and After Scheduled Joint Surgery.
The purpose of this study is to evaluate the safety of epoetin alfa and its effectiveness in facilitating the presurgical collection of blood from anemic patients for possible self-transfusion during and after scheduled joint…
- Trial name
- NCT00270062
- Testing
- epoetin alfa
- Volunteers
- 77 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Cardiac Surgery
Evaluate the Protective Effect of Conditioning With Sevoflurane on the Myocardium
Heart surgery is a considerable source of stress for the myocardium that must be minimized. Troponin Ic is a reliable marker to determine the level of this myocardial stress.
- Trial name
- SUPRA (NCT02851433)
- Testing
- total anaesthesia and postoperative inhaled sedation with Sevoflurane, total intravenous anaesthesia with Propofol.
- Where
- France
- Volunteers
- 82 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Anesthesia, Fasting
The Effect of Mobilization on Gastric Emptying Time
ıntroduction Pulmonary aspiration under general anesthesia is a rare but serious complication in healthy patients undergoing elective surgery.
- Trial name
- NCT05981638
- Testing
- group WM, group WR, Group AR
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Uludag University
Infants Aged 0 Days to 13 Months Scheduled for Elective Surgery
Effect of Pressure Support Ventilation During Anesthetic Emergence on Postoperative Atelectasis in Infant
Atelectasis occurs in patients of all ages who receive mechanical ventilation under general anesthesia, and although fatal cases are rare, it is known as a cause of postoperative hypoxia or fever.
- Trial name
- NCT05373589
- Testing
- conventional ventilation, group C, pressure support, group PS
- Where
- South Korea
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Postoperative Infection
Safety of 1 g and 2 g of Cefazolin in Pediatric Subjects
This is a Phase 4, open-label, single-dose, parallel-group, multicenter, safety study of cefazolin (1 g or 2 g) in pediatric subjects between 10 and 17 years of age (inclusive) scheduled for surgery.
- Trial name
- NCT03231228
- Testing
- Cefazolin 1 g Infusion, Cefazolin 2 g Infusion
- Where
- 5 sites in United States
- Volunteers
- 61 people
- Sponsor
- B. Braun Medical Inc.
Anxiety Postoperative
Impact on Anxiety of a Digital Application for Children Undergoing Scheduled Ambulatory Surgery
The prospect of pediatric surgery is a source of preoperative anxiety for children and their parents. It affects 50% of children waiting for surgery and the causes vary according to age.
- Trial name
- KOALOU (NCT06227663)
- Testing
- KOALOU(®) digital application
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Centre Hospitalier de Valenciennes
Prostate Cancer
GM-CSF Before Surgery in Treating Patients With Localized Prostate Cancer
RATIONALE: Colony-stimulating factors, such as GM-CSF, may help the body build an effective immune response to kill tumor cells. Giving GM-CSF before surgery may be an effective treatment for localized prostate cancer.
- Trial name
- NCT00305669
- Testing
- sargramostim, immunohistochemistry staining method, immunological diagnostic method
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, San Francisco
Neuroblastoma
Combination Chemotherapy in Treating Young Patients Who Are Undergoing Surgery and an Autologous Bone Marrow Transplant for Disseminated Neuroblastoma
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00365755
- Testing
- carboplatin, cisplatin, cyclophosphamide
- Sponsor
- Children's Cancer and Leukaemia Group
Infections
Pediatric Cefazolin PK Study
The primary objective of this study is: To examine the pharmacokinetics (PK) of cefazolin in children aged 10 to 12 years (inclusive) receiving weight-dependent 1gram (g) or 2g of cefazolin intravenous (IV) delivered over 30…
- Trial name
- NCT01904357
- Testing
- Cefazolin 1 GM Injection, Cefazolin 2 GM Injection
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- B. Braun Medical Inc.