Clinical trials: Stress Reaction
Stress Fracture, Ultrasound Therapy
Comparison of Ultrasound and X-ray as Screening Tests for Diagnosis of Lower Extremity Stress Fracture.
Hypothesis: Diagnostic ultrasound is an appropriate screening test for acute stress fracture in the lower extremity and is superior to x-ray.
- Conditions
- Stress Fracture, Ultrasound Therapy, Musculoskeletal Ultrasound
- Trial name
- NCT03116360
- Testing
- Diagnostic Ultrasound
- Volunteers
- 200 people
- Sponsor
- University of Virginia
Suicide Mortality
The Developmental Origins of Suicide Mortality
Background: Suicide rates are rising. In 2013, it was the third leading cause of death in children ages 10-14. It was the second leading cause of death for ages 15-24. Many risk factors for suicide have been found.
- Trial name
- NCT03027440
- Where
- United States
- Volunteers
- 52,966 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Spondylolysis Lumbar
A Pilot Study on the Safety of Active Conservative Management of Low Grade Lumbar Stress Reactions in Adolescent Soccer Players
Introduction: The Background Prevalence: Low back pain (LBP) is very common in young athletes, and lumbar spondylolysis (an overuse injury of bones in the low back) is the leading cause.
- Trial name
- ActiveBack (NCT07430072)
- Testing
- Active rehabilitation protocol
- Where
- 3 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Western Norway University of Applied Sciences
Vitamin D Deficiency, Stress Fracture
Vitamin D3 Supplementation and Stress Fracture Occurrence in High-Risk Collegiate Athletes
The main objective of this study is to find a correlation between vitamin D deficiency and stress fracture occurrences in athletes who participate in high-risk activities.
- Conditions
- Vitamin D Deficiency, Stress Fracture, Athletic Injuries, Orthopedic Disorder
- Trial name
- NCT03395171
- Testing
- Cholecalciferol (Vitamin D3)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Midlands
Anxiety and Fear, Anesthesia
Evaluating Stress Response and Anxiety Score in Paediatric Patients
To date, there have been no studies done relating serum cortisol levels and intranasal dexmedetomidine sedation. However, there was a behavioral study done on pediatric patients confirming reduction serum cortisol levels with…
- Trial name
- NCT04526652
- Testing
- Dexmedetomidine
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
PCOS
Effects of Triple Drug Cocktail Therapy on Metabolic, Endocrine Alterations and Perceived Stress in Patients With Poly Cystic Ovary Syndrome
The investigators aim is to conduct a double blind randomized clinical trial, to study the effects of triple drug cocktail (metformin, pioglitazone and acetyl L-Carnitine) therapy on metabolic, endocrine alterations and perceived…
- Trial name
- PCOS (NCT04113889)
- Testing
- Metformin (1000 mg daily), Pioglitazone (30 mg daily), Acetyl-L-carnitine (3 gm daily)
- Where
- Pakistan
- Volunteers
- 147 people
- Sponsor
- Khyber Medical University Peshawar
Pain, Postoperative, Agitation States as Acute Reaction to Exceptional Stress
Gabapentin as Preanesthetic Medication to Fast Procedures in Pediatric´s Oncology
This study is a clinical trial, prospective, randomized and double-blinded. Placebo, Gabapentin syrup at 15 mg/kg, and Gabapentin syrup at 30 mg/kg were administered to reduce agitation before and after in children submitted…
- Conditions
- Pain, Postoperative, Agitation States as Acute Reaction to Exceptional Stress, Anesthesia, Vomiting
- Trial name
- NCT03681574
- Testing
- GABA 15mg/kg Group, GABA 30mg/kg Group
- Where
- Brazil
- Volunteers
- 135 people
- Sponsor
- Hospital Infantil Albert Sabin
Stress Fracture, Injury
Vitamin D Supplementation in the Armed Forces
The study will comprise of an original investigation that will take the form of a prospective intervention (two matched groups) study.
- Trial name
- D_SAF (NCT03963128)
- Testing
- Supplementation Vitamin D3
- Where
- United Kingdom
- Volunteers
- 4,450 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Race-related Stress, Depression, Anxiety
Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease
The current study seeks to build on previous research that demonstrates the efficacy of Acceptance and Commitment Therapy in combating stigma by investigating the feasibility and acceptability of a protocol to support Black…
- Conditions
- Race-related Stress, Depression, Anxiety, Quality of Life, Stress Reaction
- Trial name
- ACT for SCD (NCT05685368)
- Testing
- ACT for SCD
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Children's Hospital Los Angeles
Relative Energy Deficiency in Sport, Bone Stress Reaction
Relative Energy Deficiency in Sport and Dance
The International Olympic Committee recently published its consensus statement on relative energy deficiency syndrome (REDs) in sport which was followed by a similar version for dance by clinicians and researchers in dance.
- Trial name
- NCT06480682
- Testing
- Dual x-ray scan, Blood screen, Questionnaires
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Wolverhampton
Premature Infant
Bonding Quality and Gene Expression in Fullterm Infants Compared to Late Preterm Infants and Preterm Infants With Early Skin to Skin or Visual Contact
Recent research has identified differences in the quality of mother-child interaction and gene expression of six key molecules involved in stress response and neurobehavioral development in preterm infants (born <32 weeks of…
- Trial name
- NCT03366285
- Testing
- Attachment story completion taks (ASCT)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University of Cologne
Gastro-Oesophageal Reflux
Laparoscopy in Children: Does it Decrease the Metabolic, Endocrine and Inflammatory Stress Response to Surgery
The aim of this trial was to characterise the intra and post operative metabolic, endocrine and inflammatory response to laparoscopic fundoplication in children.
- Trial name
- NCT00231543
- Testing
- Laparoscopic fundoplication, open Nissen fundoplication
- Where
- United Kingdom
- Sponsor
- Institute of Child Health
Stress Reaction; Acute
Racial Discrimination and Stress Response
The goal of this study is to learn about whether ethnic minority adolescents' racial discrimination experience is related to dysregulated biological responses to subtle racism, and how the relationship may be attenuated or…
- Trial name
- NCT05820659
- Testing
- peer rejection task, conversation about peer rejection, and impossible puzzle task
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Western Kentucky University
Diabetes Mellitus, Non-Insulin Dependent, Non-Insulin Dependent
Study of the Effects of Vitamin C on Patients With Type 2 Diabetes
Diabetes is a disease characterized by decreased sensitivity to the action on insulin to promote sugar (glucose) use and blood vessel relaxation (vasodilation) in muscle.
- Trial name
- NCT00001870
- Testing
- Acetylcholine
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Premature; Infant, Light-for-dates
Cue-based Tactile Stimulation and Infant Stress Reactivity
The present study is an examination of cue-directed tactile stimulation (CTDS), administered by mothers and NICU nurses, on infant and maternal stress reactivity, infant immune system functioning, maternal parenting cognitions…
- Trial name
- NCT01121523
- Testing
- Cue directed tactile stimulation
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Penn State University
Stress Reaction, Stress, Psychological
Effects of Stress on Team Coordination and Performance
Healthcare teams often encounter challenging circumstances where they must deliver high-quality care. For a team to function effectively, its members must not only be individually competent, but they also need to collaborate and…
- Conditions
- Stress Reaction, Stress, Psychological, Stress, Physiological
- Trial name
- NCT05798052
- Testing
- Psychological stressors added to simulated clinical scenarios.
- Where
- Canada
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Hemodynamic Instability
Role of Nebulized Dexmedetomidine in Blunting the Effects of Direct Laryngoscopy and Endotracheal Tube on Heart Rate and Blood Pressure.
The goal of this interventional study is to check the effectiveness of nebulized Dexmedetomidine in preventing the rise in blood pressure and heart rate in patients undergoing General Anesthesia.
- Trial name
- NCT06103721
- Testing
- Dexmedetomidine Injection [Precedex], Normal Saline
- Where
- Pakistan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Muhammad Haroon Anwar
Professional Burnout, Professional Stress
Impact of a Curriculum About Professionalism on Stress Response During a Critical Situation
The purpose of this study is to evaluate the impact of a curriculum about professionalism on stress response during a critical situation in anesthesiology residents.
- Conditions
- Professional Burnout, Professional Stress, Anesthesia, Medical Education
- Trial name
- NCT04192097
- Testing
- Professionalism curriculum
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Grenoble Alps
Oxidative Stress, Adaptation Reaction
Effect of an Antioxidant-rich Diet During Moderate Altitude Training
Athletes, especially in endurance sports, are at increased risk of oxidative stress and inflammation-related diseases and injuries.
- Conditions
- Oxidative Stress, Adaptation Reaction, Inflammation
- Trial name
- ALTAX (NCT03088891)
- Testing
- Antioxidant-rich snacks, Control snacks
- Where
- 2 sites in Norway
- Volunteers
- 35 people
- Sponsor
- University of Oslo
Anorexia Nervosa
The Role of Short-chain Fatty Acids in Malnutrition on Stress, Eating Behavior, and Nutritional State
This clinical trial aims to test the psychobiological effects of certain substances produced by gut bacteria, known as short-chain fatty acids (SCFAs), in people with anorexia nervosa.
- Trial name
- NCT06064201
- Testing
- Short-chain fatty acids (SCFAs)
- Where
- Belgium
- Volunteers
- 92 people
- Sponsor
- KU Leuven