Clinical trials: Sleeve Gastrectomy
Morbid Obesity, Diabetes
Factors Influencing the Positive Outcome of Bariatric Surgery for Morbidly Obese Patients
The purpose of this study is to report data with patients after bariatric surgery.
- Conditions
- Morbid Obesity, Diabetes, Hypertension
- Trial name
- NCT01583790
- Where
- Israel
- Volunteers
- 2,000 people
- Sponsor
- Assuta Hospital Systems
Obesity, Morbid, Back Pain
THE EFFECT OF FAST WEIGHT EFFICIENCY AFTER LAPAROSCOPIC SLEEVE GASTRECTOMY ON THE COBB ANGLE IN MORBID OBESE PATIENTS
Obesity has become an increasingly common health problem today. In this context, although many anatomical, physiological and metabolic problems arising from obesity in morbid obese patients are tried to be solved in daily…
- Conditions
- Obesity, Morbid, Back Pain, Scoliosis
- Trial name
- NCT04844320
- Testing
- Cobb angle measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Gastroesophageal Reflux Disease (GERD)
Evaluation of the Effectiveness of the Ezisurg Stapling (Ezi Endo Lite) During Laparoscopic Nissen Sleeve Gastrectomy
The Nissen Sleeve technique consists of creating a gastric total fundoplication (Nissen technique) before to perform the removal of 2/3 of the stomach (SLEEVE technique), intends for decrease the rate of gastroesophageal reflux…
- Trial name
- NCT07344935
- Testing
- Ezisurg stapler SLEEVE technique, Ethicon Stapler SLEEVE technique
- Where
- France
- Volunteers
- 167 people
- Sponsor
- Ezisurg Medical Co. Ltd.
Gastroesophageal Reflux Disease, Excessive Weight Loss
Sleeve Gastrectomy With Reestablishment of the Acute Angle of His (SG-REACH) in Obese Patients
Gastroesophageal reflux disease (GERD) is one of the most common chronic conditions that can affect one's quality of life. Laparoscopic sleeve gastrectomy (LSG) has become a popular technique and currently is the most frequently…
- Conditions
- Gastroesophageal Reflux Disease, Excessive Weight Loss, Total Weight Loss, Sleeve Gastrectomy
- Trial name
- SG-REACH (NCT05452980)
- Testing
- reestablishment of the acute angle of His, sleeve gastrectomy
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Zhen Jun Wang
Adolescent Obesity
Antrum Size, Glucagon-like Peptide 1 Levels and Glycemic Control After Sleeve Gastrectomy in Morbid Obese Diabetic Adolescents
Childhood obesity can adversely affect every organ and often has serious consequences. Compare the effect of transection at 2cm vs at 5cm from the pylorus during laparoscopic sleeve gastrectomy on the postoperative weight loss…
- Trial name
- NCT04388059
- Testing
- Laparoscopic sleeve gastrectomy
- Volunteers
- 18 people
- Sponsor
- Tanta University
Pediatric Obesity, Metabolic and Bariatric Surgery
Early Reinitiation of Semaglutide Post-Sleeve Gastrectomy in Youth
This is a Phase 3a, randomized, parallel-controlled trial designed to compare the early re-initiation of semaglutide, starting two weeks after sleeve gastrectomy, to standard care (no pharmacotherapy following surgery).
- Conditions
- Pediatric Obesity, Metabolic and Bariatric Surgery, Semaglutide
- Trial name
- NCT06934655
- Testing
- Semaglutide 2.4 mg
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's Hospital Los Angeles
Pediatric Obesity
Medications After Adolescent Bariatric Surgery
This study will assess the feasibility to assess practicality of early weight loss medication usage in adolescent patients post-VSG with inadequate weight loss.
- Trial name
- MAABS Protocol (NCT04572217)
- Testing
- Topiramate, Phentermine
- Where
- United States
- Sponsor
- Janey Pratt
Obesity
Gastric Mucosal Mast Cells, Macrophages and Microvessels in Obesity
This comparative cross-sectional study compared tryptase-positive mast cells, CD68-positive macrophages, and CD31-positive microvessels in the gastric mucosa of 31 patients with obesity undergoing sleeve gastrectomy and 33…
- Trial name
- NCT07448896
- Testing
- Sleeve gastrectomy, Diagnostic upper gastrointestinal endoscopy with biopsy
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Cholelithiasis
Effectiveness of Ursodeoxycholic Acid Use in the Prevention of Gallstone Formation After Sleeve Gastrectomy
This is a randomized double-blind placebo-controlled trial with a total of 100 patients who are free of gallstones at baseline. The study involves taking an oral drug (Ursodeoxycholic Acid 250mg) or a placebo twice daily for a…
- Trial name
- NCT02721862
- Testing
- Ursodeoxycholic Acid, Gallbladder Ultrasound
- Where
- 2 sites in Lebanon
- Volunteers
- 100 people
- Sponsor
- American University of Beirut Medical Center
Obesity, Morbid, Pain, Postoperative
Efficacy of CPPLAI in Laparoscopic Sleeve Gastrectomy Patients
The high demand for bariatric surgery due to the increasing prevalence of obesity worldwide necessitate evidence-based clinical pathway such as Enhanced Recovery After Bariatric Surgery (ERABS).
- Trial name
- CPPLAI (NCT04680923)
- Testing
- CPPLAI, Bupivacaine 0.25%
- Where
- Saudi Arabia
- Volunteers
- 120 people
- Sponsor
- King Khalid University Hospital
Diabetes Mellitus Type 2 in Obese
Randomized Comparative Study of Sleeve Gastrectomy Versus MGB and SASI Bypass , Randomized Study
the investigator Randomized and compare the efficacy of 3 types of metabolic surgery in the treatment of type 2 diabetes in obese patients, one of them is SASI bypass which is a modification of Santoro's operation by performing a…
- Trial name
- NCT03394157
- Testing
- metabolic surgery
- Volunteers
- 800 people
- Sponsor
- tarek mahdy
Obesity, Adolescent Obesity
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
The study plans to learn more about what happens to the body after bariatric surgery in people 12 to 24 years old. The study aims to understand why people respond differently to bariatric surgery and how to define success beyond…
- Conditions
- Obesity, Adolescent Obesity, Body-Weight Trajectory, Weight Loss Trajectory
- Trial name
- PRESSURE (NCT06575738)
- Testing
- Injectable semaglutide or injectable tirzepatide, Standard postoperative care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Obese Adolescents
Comparison Between Gastric Band, Laparoscopic Sleeve Gastrectomy, Gastric Bypass Surgeries
Determine the short and long term safety and efficacy of the Gastric bypass , laparoscopic sleeve gastrectomy, and Gastric banding (LAGB) on severely obese adolescents.
- Trial name
- NCT02004561
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Yale University
Sleeve Gastrectomy, Magnesium Sulfate
Effect of Adding Magnesium Sulphate to Bupivacaine in Laparoscopic Periportal Preperitoneal Local Infiltration in Laparoscopic Sleeve Gastrectomy
EFFECT OF ADDING MAGNESIUM SULPHATE TO BUPIVACAINE IN LAPAROSCOPIC PERIPORTAL PREPERITONEAL LOCAL INFILTRATION IN LAPAROSCOPIC SLEEVE GASTRECTOMY Our study shows that adding magnesium to the block will prolong duration of…
- Conditions
- Sleeve Gastrectomy, Magnesium Sulfate, Bupivacaine
- Trial name
- NCT07451327
- Testing
- ADDING MAGNESIUM SULPHATE TO BUPIVACAINE IN LAPAROSCOPIC PERIPORTAL PREPERITONEAL LOCAL INFILTRATION IN LAPAROSCOPIC SLEEVE GASTRECTOMY
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Alexandria University
Reflux Disease, Gastro-Esophageal, Hiatal Hernia
Treatment of Reflux With Sleeve Gastrectomy
In 2008, the World Health Organization (WHO) report found that 0.5-1.5 billion people aged 20 years and above suffer from overweight (body mass index (BMI) ≥ 25) and obesity (BMI ≥ 30 kg / m2) stated.
- Conditions
- Reflux Disease, Gastro-Esophageal, Hiatal Hernia, Reflux Esophagitis
- Trial name
- NCT06170060
- Testing
- Laparoscopic Sleeve Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Yusuf Emre ALTUNDAL
Gastroesophageal Reflux
Long Term Incidence and Effect of de Novo GERD After Laparoscopic Sleeve Gastrectomy in Chinese Population
To evaluate the long-term incidence and effects of gastroesophageal reflux disease in the Chinese population after laparoscopic sleeve gastrectomy.
- Trial name
- NCT04237857
- Testing
- Laparoscopic sleeve gastrectomy
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
Sleeve Gastrectomy, Pre-cardial Fat Pad
Preserving the Pre-cardial Fat Pad During Sleeve Gastrectomy on Postoperative Gastroesophageal Reflux
Gastroesophageal reflux disease (GERD) is one of the most common chronic conditions that can affect one's quality of life. Laparoscopic sleeve gastrectomy (LSG) has become a popular technique and currently is the most frequently…
- Conditions
- Sleeve Gastrectomy, Pre-cardial Fat Pad, Excessive Weight Loss, Total Weight Loss
- Trial name
- Pad and SG (NCT06732661)
- Testing
- Preserve pre-cardial fat pad, Dissect pre-cardial fat pad
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Chao Yang Hospital
Gastroesophageal Reflux
Prevalence, Predictors and Management of Gastroesophageal Reflux After Laparoscopic Sleeve Gastrectomy
From January 2017 to January 2022, we looked at patients who had primary LSG and developed GERD. Before and after surgery, patients for LSG performed barium meal in Trendelenburg position and upper GIT endoscopy.
- Trial name
- LSG-GERD (NCT05416645)
- Testing
- patients with GERD after LSG
- Where
- Egypt
- Volunteers
- 1,537 people
- Sponsor
- Mansoura University
Hemostasis
A Videographic Study to Evaluate the Impact of a Pulsed Firing Technique on Staple Line Interventions in Laparoscopic Sleeve Gastrectomy
Prospective, multi-center study will evaluate a pulsing technique with the ECHELON FLEX GST system for hemostasis at the staple line in laparoscopic sleeve gastrectomy procedures.
- Trial name
- NCT03896061
- Testing
- Laparoscopic sleeve procedures
- Where
- 3 sites in United States
- Volunteers
- 62 people
- Sponsor
- Ethicon, Inc.
Bariatric Surgery, Sleeve Gastrectomy
Prediction Model for Inadequate Weight Loss After Sleeve Gastrectomy
This study aims to develop and validate a prediction model for estimating the probability of inadequate weight loss one year after sleeve gastrectomy.
- Conditions
- Bariatric Surgery, Sleeve Gastrectomy, Weight Loss
- Trial name
- NCT06157606
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- China-Japan Friendship Hospital