Clinical trials: Sinusitis, Chronic
Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
Chronic Otitis Media With Effusion in Chronic Sinusitis With Polyps
The relationship between otitis media with effusion (OME) and chronic rhinosinusitis with nasal polyposis (CRSwNP) remains unclear.
- Trial name
- NCT03975842
- Testing
- Sinonasal and otologic evaluation
- Volunteers
- 80 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Chronic Sinusitis
Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic Rhinosinusitis
The propose of this study to determine efficacy and complication of gentamicin nasal irrigation in chronic rhinosinusitis
- Trial name
- NCT01430026
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Asthma, Rhinitis
Study of Asthma and Nasal Steroids
The trial will study the effectiveness of nasal steroids for the treatment of chronic rhinitis and/or sinusitis on asthma control.
- Conditions
- Asthma, Rhinitis, Sinusitis
- Trial name
- STAN (NCT01118312)
- Testing
- Mometasone Furoate monohydrate
- Where
- 19 sites in United States
- Volunteers
- 388 people
- Sponsor
- JHSPH Center for Clinical Trials
Epistaxis, Nasal Obstruction
The Effect of Packing in Post Operative Management of FESS
Chronic sinusitis is a very common problem. The functional endoscopic sinus surgery is a prevalent option to treat this disease.During usage of different techniques of surgery, the need for packing after surgery is debatable…
- Conditions
- Epistaxis, Nasal Obstruction, Pain
- Trial name
- NCT00793117
- Testing
- packing
- Where
- Iran
- Volunteers
- 66 people
- Sponsor
- Tehran University of Medical Sciences
Cystic Fibrosis, Sinusitis
Prevalence of Chronic Rhinosinusitis in Cystic Fibrosis
Aim of the study is to detect the prevalence of chronic rhinosinusitis and the colonisation with Pseudomonas aerug. in the upper airways in patients with cystic fibrosis.
- Trial name
- NCT00266474
- Testing
- Assessment of upper and lower airway colonization, sinonasal symptoms, history, rhinoscopy and rhinomanometry.
- Where
- Germany
- Volunteers
- 187 people
- Sponsor
- University of Jena
Chronic Rhinitis, Inflammation of the Nasal Mucosa
Surgical Reduction of the Inferior Turbinates for Nasal Obstruction
The primary goal of this post-marketing surveillance study is to assess whether surgical turbinate reduction performed using a Coblation® device is associated with reduced nasal obstruction symptoms.
- Conditions
- Chronic Rhinitis, Inflammation of the Nasal Mucosa, Inflammation of Nasal Tissue
- Trial name
- NCT00737906
- Testing
- Surgical turbinate reduction procedure
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- ArthroCare Corporation
Sinusitis, Cystic Fibrosis
Nasally Delivered Pulmozyme for Sinusitis in Cystic Fibrosis
Chronic sinusitis is a frequent complication in cystic fibrosis. The aim of this study is to determine whether Pulmozyme(dornase alfa) would maintain sinus health (compared to placebo) in patients with cystic fibrosis who have…
- Trial name
- NCT00416182
- Testing
- Pulmozyme (dornase alfa)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Vermont
Sinusitis
Comparing the Use of Saline or Saline Plus Gentamycin in Nasal Irrigation to Treat Chronic Sinusitis in Children
Healthy children may develop symptoms of chronic sinusitis such as chronic cough, chronic runny nose, nasal congestion, even headaches.
- Trial name
- NCT00465530
- Testing
- Saline, Gentamycin
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Julie Wei, MD
Pediatric Cancer, Chronic Sinusitis
Post-radiotherapy Rhinosinusitis in Children
Chronic rhinosinusitis (CRS) is a frequent complication of facial cancer treatment, mainly related to radiotherapy. However, while radiological involvement is frequent, clinical expression seems less important.
- Trial name
- PRRSC (NCT05454163)
- Testing
- SNOT 22 questionnaire
- Sponsor
- University Hospital, Lille
Pulmonary Disease, Chronic Obstructive, Bronchospasm
Prophylactic Efficacy of Relenza Against Influenza A and B
In response to the European regulatory authorities, GSK is conducting a post-marketing observational study to assess the efficacy of Relenza when used as prophylaxis against influenza. SPECIFIC AIMS 1.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Bronchospasm, Influenza, Human, Asthma
- Trial name
- NCT01156701
- Testing
- Receiving a prescription of Relenza for prophylaxis, No prophylaxis with Relenza
- Volunteers
- 171,705 people
- Sponsor
- GlaxoSmithKline
Chronic Sinusitis
Clinical Study to Improve Diagnosis and Treatment of Sinusitis
Chronic rhinosinusitis (CRS) is the most common chronic medical condition that affects Americans between 18-44 years of age. While significant advances have been made in the understanding of the molecular pathogenesis underlying…
- Trial name
- NCT00962689
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Ohio State University
Chronic Sinusitis, Radiology
Research on Identifying and Treatment Prognosis of Chronic Rhinosinusitis Based on Image and Sequencing Data
This project focuses on researching chronic rhinosinusitis in patients, employing image processing techniques and molecular biology methods to jointly determine the research objectives: 1. Investigating heterogeneity. 2.
- Conditions
- Chronic Sinusitis, Radiology, Pathology, Surgery
- Trial name
- NCT05983003
- Testing
- endoscopic sinus surgery
- Where
- China
- Volunteers
- 3,500 people
- Sponsor
- Zheng Liu
Cystic Fibrosis, Rhinosinusitis
Nasal Inhalation of Pulmozyme in Patients With Cystic Fibrosis and Chronic Rhinosinusitis
Rhinosinusitis disorders are often associated with Cystic Fibrosis. They can restrict quality of life enormously and give cause to repeated ENT surgery.
- Trial name
- NCT00534079
- Testing
- Dornase alfa (Pulmozyme), isotonic saline
- Where
- 2 sites in Germany
- Volunteers
- 23 people
- Sponsor
- University of Jena
Chronic Sinusitis, Adenoid Disease - Chronic
Management of Pediatric Chronic Rhinosinusitis in Asthmatic Children
The objectives of this study would be to determine the most effective management for pediatric patients with chronic rhinosinusitis and asthma who fail medical management.
- Trial name
- NCT03336671
- Testing
- Endoscopic Sinus surgery, Adenoidectomy
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Chronic Sinusitis
Vitamin D Supplementation in Chronic Rhinosinusitis With Nasal Polyps
The purpose of this study is to determine if Vitamin D supplementation improves clinical and immunologic parameters in chronic rhinosinusitis with nasal polyps.
- Trial name
- VDinCRS (NCT01185808)
- Testing
- Vitamin D
- Where
- United States
- Sponsor
- Medical University of South Carolina
Rhinitis + Sinusitis, Pediatric Chronic Rhinosinusitis
Study for the Management of Pediatric Chronic Rhinosinusitis With or Without Balloon Sinuplasty
Chronic rhinosinusitis, a common diagnosis in children, remains a poorly understood disease. Adenoidectomy (surgery to take out the adenoid pads- infection fighting glands in the back of the throat) is performed since the adenoid…
- Trial name
- NCT01990820
- Testing
- Acclarent Relieva Balloon Sinuplasty, Adenoidectomy + Maxillary Sinus Irrigation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Endeavor Health
Cystic Fibrosis With Other Manifestations, Sinusitis
Longitudinal Pathogen-colonization in Cystic Fibrosis Airways and Ability to Smell
Aim of the study is to detect the prevalence of chronic rhinosinusitis, pathogen colonization of the lower and upper airways and, in a sub-cohort the sense of smelling in patients with cystic fibrosis.
- Trial name
- NCT00803881
- Testing
- nasal lavage and sputum collection
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University of Jena
Chronic Sinusitis
Study of ONO-1078 in Patients With Chronic Sinusitis
To determine the efficacy and safety of ONO-1078 in patients with chronic sinusitis in a double-blind, randomized, placebo-controlled, parallel group, multi-center study
- Trial name
- NCT00410735
- Testing
- Pranlukast hydrate
- Where
- 6 sites in Japan
- Volunteers
- 495 people
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Conscripts, Military Induction Board
Prevalence of ENT Diseseas
The aim of the present study will be to evaluate in conscripts at the military induction board the prevalence of rhinosinusitis, the prevalence of HPV vaccinations, the prevalence of hearing impairments and the prevalence of…
- Conditions
- Conscripts, Military Induction Board, ENT Disease, Rhinosinusitis Chronic
- Trial name
- PrENT (NCT06105346)
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Chronic Rhinosinusitis (Diagnosis)
Adrenaline Solution Irrigation and Bleeding During Sinus Surgery
Intranasal irrigation with normal saline is routinely used in sinus surgery to clean the tip of the nasal endoscope and clear the surgical field from blood.
- Trial name
- NCT04551703
- Testing
- Adrenaline saline irrigation
- Volunteers
- 60 people
- Sponsor
- Jordan University of Science and Technology