Clinical trials: Respiratory Syncytial Virus (RSV), open to volunteers
Respiratory Syncytial Virus Infections
A Study of BLB-201 RSV Vaccine in Infants and Children
This Phase 1/2a trial is a randomized, placebo-controlled trial to evaluate the safety, tolerability and immunogenicity of two ascending doses (10^6 PFU and 10^7 PFU) of intranasal BLB-201 (a recombinant parainfluenza virus type…
- Trial name
- NCT05655182
- Testing
- PIV5-vectored RSV Vaccine (BLB-201) Low Dose, PIV5-vectored RSV Vaccine (BLB-201) High Dose
- Where
- 18 sites in United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Blue Lake Biotechnology Inc.
Respiratory Syncytial Virus (RSV)
Peginterferon α-2b Injection for Aerosol Therapy in Pediatric Respiratory Syncytial Virus Pneumonia
This is a multicenter, randomized, open-label, parallel-controlled, prospective clinical study. It aims to evaluate the efficacy and safety of aerosolized Peginterferon α-2b injection in the treatment of pediatric respiratory…
- Trial name
- NCT06881056
- Testing
- Peginterferon α-2b injection, symptomatic and supportive treatment
- Where
- 2 sites in China
- Volunteers
- 90 people
- Sponsor
- West China Second University Hospital
Respiratory Syncytial Virus Infections
Evaluating the Benefits of RSV Maternal Vaccination Using a Scottish National Dataset
This study will use a retrospective cohort design and will be conducted within routinely collected national healthcare and statutory demographic datasets held by PHS and National Records of Scotland (NRS).
- Trial name
- BORLAND (NCT07235397)
- Testing
- ABRYSVO
- Volunteers
- 1 people
- Sponsor
- Pfizer
Respiratory Syncytial Virus (RSV)
Study to Learn About a Respiratory Syncytial Virus Vaccine in Children at High Risk of RSV Disease
The purpose of the study is to evaluate the safety, tolerability, and immunogenicity of RSVpreF in children 5 to <18 years of age at high risk for RSV disease, including those who are immunocompromised.
- Trial name
- NCT07839871
- Testing
- RSVpreF
- Where
- 20 sites in United States, Japan and 2 more
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Pfizer
Respiratory Syncytial Virus Infection, Bronchiolitis
Gut Microbiome and Immune Response in Severe RSV Infection in Vietnamese Infants
Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory tract infection in young children, and a substantial proportion of severe cases occur in previously healthy infants.
- Conditions
- Respiratory Syncytial Virus Infection, Bronchiolitis, Viral Lower Respiratory Tract Infection (LRTI)
- Trial name
- GUT-LUNG RSV (NCT07417657)
- Where
- Vietnam
- Volunteers
- 250 people
- Sponsor
- Phuc Huu Phan
RSV Infection
Real-World Effectiveness of Perinatal RSV Immunoprophylaxis
The purpose of this study is to continue evaluating how well the RSV vaccines work as they are currently being used in routine clinical practice.
- Trial name
- NCT06172660
- Testing
- Nirsevimab
- Where
- United States
- Volunteers
- 3,750 people
- Sponsor
- Yale University
Respiratory Syncytial Virus Infections
Human Interferon α1b Inhalation Solution Against Respiratory Syncytial Virus in Children With Lower Respiratory Tract Infections
To evaluate the efficacy and safety of interferon α1b (GB05) in the treatment of children under 2 years of age with respiratory syncytial virus infection.
- Trial name
- NCT06363370
- Testing
- Human interferon α1b Inhalation Solution
- Where
- China
- Volunteers
- 322 people
- Sponsor
- Kexing Biopharm Co., Ltd.
Respiratory Syncytial Virus (RSV) Infection, Acute Lower Respiratory Tract Infections
Assessing the Burden of Respiratory Syncytial Virus (RSV)
This study examines the impact of Respiratory Syncytial Virus (RSV) on people of all ages, from infants to the elderly. It uses hospital records collected between January 2018 and December 2024 to understand: How often does RSV…
- Conditions
- Respiratory Syncytial Virus (RSV) Infection, Acute Lower Respiratory Tract Infections, Bronchiolitis, Pneumonia
- Trial name
- NCT07015255
- Where
- United Arab Emirates
- Volunteers
- 1,500 people
- Sponsor
- Abu Dhabi Health Services Company
Bronchiolitis
Association of Dysbiosis and Immune Response in Bronchiolitis in Under 12 Months -Old Infants
Acute bronchiolitis is a common disease in children under the age of two, caused mainly by the respiratory syncytial virus (RSV).
- Trial name
- BRONCHOBIOTE (NCT06161285)
- Testing
- Sampling
- Where
- 3 sites in France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Syncytial Virus (RSV), Respiratory Infection Virus
THRIVE - Trial of Passive Humoral RSV Immunity for Value and Effectiveness
RSV is a leading cause of severe respiratory illness and hospitalisation for young children, with particularly high rates of RSV respiratory infection observed amongst Aboriginal and Torres Strait Islander children living in…
- Trial name
- THRIVE (NCT07578298)
- Testing
- Nirsevimab (RSV-specific monoclonal antibody)
- Where
- Australia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Menzies School of Health Research
Respiratory Syncytial Virus (RSV), Maternal Immunization
TARSILA Real-World Evidence Study
The overall objective of Tarsila Study is to estimate the real-world vaccine effectiveness of maternal RSVpreF immunization during pregnancy in Brazil against medically attended (inpatient and outpatient) respiratory syncytial…
- Conditions
- Respiratory Syncytial Virus (RSV), Maternal Immunization, Acute Respiratory Illness (ARI), Lower Respiratory Tract Disease
- Trial name
- TARSILA (NCT07445763)
- Testing
- respiratory syncytial virus bivalent prefusion F vaccine
- Where
- 8 sites in Brazil
- Volunteers
- 5,000 people
- Sponsor
- Inova Medical
Acute Bronchiolitis Due to Respiratory Syncytial Virus, Bronchiolitis Acute
Mucociliary Clearance Techniques for Acute Bronchiolitis
To assess the efficacy of mucociliary clearance techniques in non-hospitalised infants with a first episode of mild to moderate acute bronchiolitis.
- Conditions
- Acute Bronchiolitis Due to Respiratory Syncytial Virus, Bronchiolitis Acute, Bronchiolitis Acute Viral
- Trial name
- CLEARBRONCH (NCT06689631)
- Testing
- Respiratory Physiotherapy
- Volunteers
- 70 people
- Sponsor
- Universidad de León
Bronchiolitis
Peginterferon α-2b Injection for the Treatment of Pediatric RSV Bronchiolitis
This is a multicenter, randomized, positive-controlled, non-inferiority clinical study, planning to enroll 90 children with bronchiolitis caused by respiratory syncytial virus infection, to evaluate the safety and efficacy of…
- Trial name
- NCT06827249
- Testing
- Peginterferon α-2b injection, Recombinant Human Interferon α2b
- Where
- 3 sites in China
- Volunteers
- 90 people
- Sponsor
- Children's Hospital of Soochow University
RSV Infections, RSV Immunisation
A Clinical Trial on Safety in Pregnant Women and How Well the Infant is Protected Against RSV-associated Lower Respiratory Tract Infection When the Pregnant Woman Receives the Approved RSV Vaccine Compared to a Placebo.
Respiratory syncytial virus (RSV) is a virus that often affects children during childhood. Even though most cases of RSV are mild, it can cause serious disease and even death - especially in very young babies, babies born too…
- Conditions
- RSV Infections, RSV Immunisation, Preterm Labour
- Trial name
- NCT06955728
- Testing
- Vaccine
- Where
- 11 sites in Ghana, Kenya and 2 more
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- University of Witwatersrand, South Africa
Bronchiolitis, Acute Bronchiolitis
Risk Factors and Severity of Bronchiolitis in Hospitalized Children at Assiut University Hospital
The purpose of this observational study is to identify the risk factors that make bronchiolitis more severe in infants and toddlers.
- Conditions
- Bronchiolitis, Acute Bronchiolitis, Respiratory Syncytial Virus Infection
- Trial name
- NCT07505420
- Volunteers
- 65 people
- Sponsor
- Assiut University
Respiratory Syncytial Virus Infection
A Phase III Study of Deuremidevir Hydrobromide for the Treatment of RSV Infection in Infants and Young Children
This is a randomized, double-blind, placebo-controlled, parallel-group trial conducted in infants and young children aged 1 to 36 months with RSV infection.
- Trial name
- NCT07402512
- Testing
- SIM0916
- Where
- 4 sites in China
- Volunteers
- 498 people
- Sponsor
- Simcere Pharmaceutical Co., Ltd
Acute Respiratory Infections (ARIs)
Epidemiological Characteristics and Clinical Burden of RSV Infection in Children Under 24 Months in Ho Chi Minh City (2026-2028)
This is a prospective, observational, multicenter study employing continuous, convenience sampling, stratified by study site and by fortnightly interval, enrolling until the target sample sizes are achieved over the first…
- Trial name
- RSV pediatric (NCT07640581)
- Where
- 3 sites in Vietnam
- Volunteers
- 2,000 people
- Sponsor
- Tam Anh Research Institute
Fever, Adverse Event Following Immunisation
Safety of RSV Preventive Monoclonal Antibody
This is a prospective, randomized, open-label clinical trial to evaluate the safety of administration of respiratory syncytial virus (RSV) preventive monoclonal antibody and other routine childhood vaccines given simultaneously…
- Trial name
- NCT07158814
- Testing
- Respiratory Syncytial Virus (RSV) Preventive Monoclonal Antibody
- Where
- 6 sites in United States
- Volunteers
- 524 people, healthy volunteers welcome
- Sponsor
- Duke University
Respiratory Syncytial Virus
A Post-marketing Surveillance Study of Beyfortus (Nirsevimab) in Republic of Korea
This study is conducted as part of the local risk management plan to collect and understand the following information about the surveillance drug under the real-world clinical practice settings.
- Trial name
- NCT07200206
- Testing
- Nirsevimab
- Where
- South Korea
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Sanofi
Respiratory Syncytial Virus Infections
Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children
The overarching hypothesis of the ARRC trial is that administration of Azithromycin (AZM) during acute, Respiratory Syncytial Virus (RSV)-induced respiratory failure will be beneficial, mediated through the matrix…
- Trial name
- NCT05026749
- Testing
- AZM Group, Control Group
- Where
- 15 sites in United States
- Volunteers
- 370 people
- Sponsor
- University of Alabama at Birmingham