Clinical trials: Reproductive Disorder
Healthy, Deficiency Disease
Effects of Dietary Carbohydrate and Fat on Hormones
This study will try to determine if intake of dietary fats or carbohydrates influences the tendency to gain weight or accumulate body fat.
- Trial name
- NCT00016848
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Breast Cancer
Clinical and Biological Study of Early-onset Breast Cancer and the Influence of the Reproductive Cycle on the Aggressiveness of the Disease
The incidence of breast cancer is increasing, particularly among young women. Cancers in young women are associated with a poor prognosis. The causes remain poorly understood.
- Trial name
- ARTEMIS (NCT07601152)
- Testing
- No Intervention: Observational Cohort
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Institut Cancerologie de l'Ouest
HIV Infection, Sexual and Reproductive Health
PrEPared to Choose (PtC) is an Implementation Study of the Delivery of Cabotegravir Long-acting, an Injectable Pre-exposure Prophylaxis (PrEP) Option for HIV Prevention. Injectable PrEP Will be Offered Alongside Oral and Vaginal Ring PrEP From Within a Real-world Context in Cape Town, South Africa.
The goal of this clinical trial is to offer adolescents and young people in Cape Town, South Africa different HIV pre-exposure prophylaxis (PrEP) products and describe how they use these products over an 18-month period.
- Trial name
- PtC (NCT06807736)
- Testing
- Cabotegravir long-acting, Tenofovir emtricitabine, Dapivirine containing vaginal ring
- Where
- South Africa
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Menstrual Disorder, Premature Ovarian Failure
The Effect of HPV Vaccine on Menstrual Cycle in Women of Reproductive Age
Cervical cancer is one of the most common cancer in women, making it the fourth largest cause of female cancer mortality worldwide.
- Trial name
- NCT05838157
- Testing
- prophylactic HPV vaccine(bivalent HPV、quadrivalent HPV、9-valent HPV)
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Substance-Related Disorders, Sexually Transmitted Diseases
Adolescent Drug and HIV Prevention in South Africa
The purpose of this trial is to test the effectiveness of a classroom-based prevention program (HealthWise: Learning Life Skills for Young Adults) to reduce the risk of HIV/AIDS and STIs, as well as substance use, among…
- Trial name
- NCT00336180
- Testing
- HealthWise South Africa curriculum
- Where
- South Africa
- Volunteers
- 7,695 people, healthy volunteers welcome
- Sponsor
- Penn State University
Maternal Care Patterns, Pregnancy Related
Cash Benefits and Reproductive/Perinatal Health
During the first two years of the COVID-19 pandemic, the City of Chelsea, Massachusetts held a lottery to allocate cash benefits to its residents for ten months.
- Conditions
- Maternal Care Patterns, Pregnancy Related, Miscarriage
- Trial name
- NCT05782660
- Testing
- Cash Benefit, No Cash Benefit
- Where
- United States
- Volunteers
- 3,615 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Sexual Behavior, Adolescent Behavior
Evaluation of Parent Toolkit 2.0 (Morehouse Family Health Study)
Child Trends will conduct a randomized control trial evaluation of Parent Toolkit 2.0, an innovative intervention for parents and caregivers of middle and high school students.
- Conditions
- Sexual Behavior, Adolescent Behavior, Sexually Transmitted Diseases, Contraception Behavior
- Trial name
- NCT06579781
- Testing
- Morehouse Family Health Study's Parent Toolkit 2.0, Morehouse Family Health Study's General Health Guide
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Child Trends
Pregnancy Prevention, Sexual Behavior
Project Legacy Impact Evaluation Study
This study will design and rigorously evaluate the efficacy of Project Legacy, a five week positive youth development intervention to decrease sexual risk for unintended pregnancies and STIs among youth experiencing homelessness…
- Conditions
- Pregnancy Prevention, Sexual Behavior, Contraception Behavior, Sexually Transmitted Diseases
- Trial name
- NCT03366636
- Testing
- Project Legacy
- Where
- 12 sites in United States
- Volunteers
- 571 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Infertility
Reproductive Medicine Network Biologic Specimen Repository
The Reproductive Medicine Network (RMN) is a nationwide cooperative network of 7 clinical sites and a data coordination center, and is sponsored in 5 year increments by The Eunice Kennedy Shriver National Institute for Child…
- Trial name
- NCT01180387
- Where
- 15 sites in United States
- Volunteers
- 1,640 people
- Sponsor
- Yale University
Tumor of Female Reproductive System, Ovarian Cancer
A Cohort Establishment Study of Total Management of Ovarian Cancer
A cohort establishment study of total management of ovarian cancer (including fallopian tube cancer and primary peritoneal cancer).
- Trial name
- NCT06018935
- Testing
- No intervention
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Prostate Cancer
Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer
RATIONALE: Nerve-sparing radical prostatectomy with nerve grafting followed by standard therapies for erectile dysfunction may be effective in helping patients with prostate cancer improve sexual satisfaction and quality of life.
- Trial name
- NCT00080808
- Testing
- Alprostadil (E1), Papaverine, Phentolamine mesylate
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- M.D. Anderson Cancer Center
Cardiovascular Diseases, Heart Diseases
Reproduction and Survival After Cardiac Defect Repair
To create a registry of all Oregon children undergoing surgical repair of congenital heart disease since 1958 in order to determine mortality, morbidity, and disability after surgery and to assess the safety of pregnancy in women…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Defect, Congenital Heart, Aortic Valve Stenosis
- Trial name
- NCT00005190
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Contraception Behavior
Hormonal Contraceptive Health Education for Adolescent Males
Prospective randomized control trial of an educational electronic application on female hormonal contraception for adolescent males in the pediatric emergency department.
- Trial name
- NCT03400410
- Testing
- Education Arm
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
HIV/AIDS Prevention
Effects of an HIV Intervention Among Sex Workers in the Philippines
This study will implement a socio-behavioral intervention in Quezon City, the Philippines, using a community-based participatory approach.
- Trial name
- NCT02071264
- Testing
- HIV/STI intervention
- Where
- Philippines
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lianne Urada
Genetic Disorder, Infertility
Inherited Reproductive Disorders
Background: During puberty, children begin to develop into adults. Problems with the hormones released during puberty can affect the reproductive system. Some people have low hormone levels that severely delay or prevent puberty.
- Conditions
- Genetic Disorder, Infertility, Hypogonadism, Amenorrhea
- Trial name
- NCT01500447
- Where
- 2 sites in United States
- Volunteers
- 850 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Pregnancy Complications
Early Evaluation of the MAMAACT Trial
The MAMAACT#1 project's aim was to reduce ethnic disparity in stillbirth and infant death by improving the management of pregnancy complications through timely and appropriate response to warning signs of pregnancy.
- Trial name
- NCT04261400
- Testing
- MAMAACT
- Volunteers
- 2,000 people
- Sponsor
- University of Copenhagen
Infertility
A Non-interventional Study to Identify the Patients With Severe Luteinizing Hormone Deficiency in the Daily Practice
This non-interventional study is planned to identify the subjects with severe luteinizing hormone (LH) deficiency in the daily practice.
- Trial name
- NCT01112618
- Where
- Germany
- Volunteers
- 3,247 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Hemophilia A, Bleeding Disorder
Characterizing the Impact and Treatment of Reproductive Tract Bleeding on Women and Post-menarchal Girls With Bleeding Disorders
Characterizing the impact and treatment of reproductive tract bleeding on women and post-menarchal girls with bleeding disorders.
- Trial name
- NCT03834727
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Oregon Health and Science University
Cervical Cancer, Sexuality and Reproductive Issues
Vaginal Changes and Sexual Function in Patients With Cervical Cancer
RATIONALE: Vaginal changes that may effect sexual function occur in patients undergoing treatment for cervical cancer. PURPOSE: Clinical trial to determine the type of vaginal changes such as vaginal dryness that occur in…
- Trial name
- NCT00053261
- Testing
- management of therapy complications
- Where
- 12 sites in United States
- Sponsor
- Gynecologic Oncology Group
Sexually Transmitted Infections
Parental Knowledge and Attitudes of Confidential Sexually Transmitted Infections (STI) Services for Teens
This study will provide new and important information regarding parental knowledge and attitudes of confidential STI and related health care services (prevention, diagnosis and treatment) for teens that may be needed to address…
- Trial name
- NCT01144871
- Where
- 3 sites in United States
- Volunteers
- 1,216 people
- Sponsor
- University of California, San Francisco