Clinical trials: Regional Anaesthesia
Third Molar Extraction
Postoperative Analgesia Following Wisdom Teeth Removal: Ropivacaine Versus Placebo
The main objective of this study is to demonstrate the superiority of local analgesia with ropivacaine versus placebo on postoperative pain during the first 24 hours following bilateral surgery of all four third molars under…
- Trial name
- RopiMol (NCT01541059)
- Testing
- Ropivacaine injection
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Ilioinguinal Nerve Block, Local Anesthesia
Comparing Ilioinguinal Single-shot and Three-layer Blocks
Ilio-inguinal nerve blocks have a long history of efficacy in treatment of post-operative pain following inguinal surgery. Several anatomic studies have shown that the nerves supplying the inguinal area have a certain degree of…
- Conditions
- Ilioinguinal Nerve Block, Local Anesthesia, Post-operative Analgesia
- Trial name
- NCT01625780
- Testing
- 3-layer block, Single-shot block
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Alberta
Hypotension
Influence of Injection Rate of Intrathecal Mixture of Local Anesthesia on Hypotension in Cesarean Section
Hypotension is the most common complication of neuraxial anesthesia in obstetric patients and its prevalence in cesarean section is about 50-90%.
- Trial name
- NCT03517683
- Testing
- Low speed, High speed
- Where
- Lebanon
- Volunteers
- 159 people
- Sponsor
- Makassed General Hospital
Acute Pain, Pain, Postoperative
Supraclavicular Blocks for Post-Operative Pain Control in Supracondylar Fracture Fixation, a Retrospective Analysis of Single Shot Catheter Techniques
We hypothesize that patients who receive a supraclavicular block via Angiocath, placed intra-operatively and dosed post-operatively following neurologic examination, will have lower pain scores, lower use of intravenous morphine…
- Trial name
- NCT02210429
- Testing
- Elbow Fracture Fixation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Limb Fracture
Impact of Continuous Regional Analgesia in Severe Trauma Patients
Regional analgesia, based on its physiological effects and efficacy, is used for optimal perioperative pain relief. However, for acute pain in multiple trauma patients in a critical condition, it has not been prospectively…
- Trial name
- ALRréa (NCT04546503)
- Testing
- Continuous Regional analgesia, Control Group
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Local Anaesthetic, Dental Anxiety
Effect of a Vibration System on Pain Reduction During Injection of Local Dental Anaesthesia in Children
The study assesses the effect of a new vibration system on pain reduction during the injection of local anesthesia. Children undergoing dental treatment are allocated to two groups; one receiving the Buzz, a vibration system and…
- Trial name
- NCT03953001
- Testing
- Adminstration Technique using Buzzy external distractor, 2% Lidocaine with 1:50,000 epinephrine, Topical Anesthetic
- Where
- Saudi Arabia
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Anesthesia, Local, Ophthalmopathy
Comparison Between Peribulbar And Sub-tenon Blocks on Oculocardiac Reflex (OCR) During Pediatric Strabismus Surgery
The aim of this study is to compare between peribulbar block and subtenon block as an adjunct to general anesthesia in children undergoing strabismus surgery on oculocardiac reflex (OCR), post-operative analgesia and…
- Conditions
- Anesthesia, Local, Ophthalmopathy, Strabismus, Pediatric ALL
- Trial name
- NCT06293586
- Testing
- peribulbar block, sub-tenon block, Paracetamol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cairo University
Atrial Septal Defect, Ventricular Septal Defect
Regional Anesthesia Following Pediatric Cardiac Surgery
The purpose of this study is to evaluate pain control following pediatric cardiac surgery with the use of local anesthesia via an ultrasound guided regional anesthetic technique compared with surgeon delivered wound infiltration.
- Conditions
- Atrial Septal Defect, Ventricular Septal Defect, Pain, Procedural
- Trial name
- NCT05688670
- Testing
- Regional Anesthesia, Wound infiltration, Ropivacaine 0.2% Injectable Solution
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Duke University
Local Anesthetic Infiltration, Topical Anesthesia
Topical Cryoanesthesia Versus Benzocaine in Pediatric Dentistry
This clinical study tested and compared two ways (cold-base technique or "cryoanesthesia" and conventional benzocaine gel) to reduce pain from dental injections in children.
- Conditions
- Local Anesthetic Infiltration, Topical Anesthesia, Pain Perception
- Trial name
- No acronym (NCT07351383)
- Testing
- Local Anesthesia (lidocaine hydrochloride)
- Where
- Mexico
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Laparoscopic Appendectomy
Comparing Pain Relief Between Two Methods of Freezing Injections in Children Having Their Appendix Removed
Laparoscopic appendectomies are the most common emergency surgeries performed in children. Despite being considered minimally invasive surgeries, they can result in substantial postoperative pain and 2 of 3 patients require…
- Trial name
- NCT06945263
- Testing
- Rectus Sheath Block, Local Anesthetic at the Umbilical Port Site, Intravenous Dexamethasone
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia
Regional Anesthesia
Comparison of Caudal Block and Retrolaminar Block for Circumcision
Primary Outcome: Analgesic Efficiency: The primary outcome is the comparison of the analgesic efficacy of the retrolaminar block (RL) versus caudal block (CB) based on postoperative pain scores measured by the FLACC score.
- Trial name
- NCT06584292
- Testing
- caudal block, Retrolaminar block
- Where
- Turkey (Türkiye)
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Anesthesia, Local, Pain
Clinical Trial Comparing Effectiveness of Buffered Versus Unbuffered Local Anesthetic in Children Ages 10-12 Years
Local anesthesia is an integral part of clinical pediatric dental practice, but it has challenges. It can be uncomfortable for children, and the risk of adverse events limits how much is used.
- Trial name
- NCT03562481
- Testing
- 1% Buffered Lidocaine 1:100,000 Epinephrine, 2% Unbuffered Lidocaine 1:100,000 Epinephrine
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Patient Safety, Anesthesia
Impact of Production Pressure in the Block Room on Patient Safety
This randomized, single blinded simulation based study investigates the impact that production pressure can have on the safety of patients undergoing regional anesthesia.
- Trial name
- NCT04846660
- Testing
- Production pressure
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Hip Dislocation, Congenital, Postoperative Pain
Quadratus Lumborum Block for Pediatric Hip Surgery
Caudal blockade (CB) is one of the most frequently performed regional anaesthetic techniques in children. It's an efficient way to offer perioperative analgesia for painful sub-umbilical interventions but with high incidence of…
- Conditions
- Hip Dislocation, Congenital, Postoperative Pain, Anesthesia
- Trial name
- NCT04292782
- Testing
- anterior Quadratus lumborum block, caudal block
- Where
- Tunisia
- Volunteers
- 40 people
- Sponsor
- University Tunis El Manar
Ureteropelvic Junction Obstruction, Postoperative Pain
Ketamine Added to Quadratus Lumborum Block for Pain Relief After Infant Pyeloplasty
This prospective randomized study evaluates the effect of adding ketamine to bupivacaine in ultrasound-guided quadratus lumborum (QL) block for postoperative pain management in infants undergoing open pyeloplasty.
- Trial name
- KETA-QLB (NCT07596810)
- Testing
- Ketamine + Bupivacaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Cut Flexor Hand, Walant
Compare the Outcomes of Zone II Flexor Tendon Repair of the Hand Under General Anesthesia Versus WALANT
Comparison between results of repair of cut flexor zone II under General anesthesia and Walant
- Conditions
- Cut Flexor Hand, Walant, General Anesthesia
- Trial name
- NCT04089124
- Testing
- surgery of zone II cut flexor repair
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Assiut University
Regional Anesthesia, Pediatric Anesthesia
Continous Lumbar Plexus Block in Children
Randomised controlled prospective trial with 2 groups (active group with Lumbar plexus block (LPB)-catheter vs control group). In a randomized controlled trial, the investigators will investigate under controlled circumstances…
- Conditions
- Regional Anesthesia, Pediatric Anesthesia, Pain, Postoperative
- Trial name
- NCT03450096
- Testing
- LPB
- Where
- Switzerland
- Volunteers
- 33 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Anesthesia
Needle-Free Lidocaine Injection vs Traditional Local Anesthesia in Infant Lumbar Puncture
We hypothesize that the J-Tip needle-free jet-injection system offers comparable pain control and greater provider satisfaction due to its less invasive nature compared to traditional needle infiltration of 1% lidocaine in…
- Trial name
- NCT06552351
- Testing
- Needle-Free Jet Injection of 1 % lidocaine, traditional needle infiltration of 1% lidocaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Oklahoma
Anesthesia; Functional, Anesthesia, Local
Thoracic Intervertebral Foramen Block
The investigators hypothesize an alternative way to perform thoracic paravertebral block, by placing the needle tip over and behind the transverse process of vertebra, via the thoracic intervertebral foramen.
- Conditions
- Anesthesia; Functional, Anesthesia, Local, Spinal Cord
- Trial name
- NCT05603442
- Testing
- Thoracic intervertebral foramen block
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- San Salvatore Hospital of L'Aquila
Anesthesia, Local
Comparing the Hemodynamic Effects of Epinephrine Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Caudal Anaesthesia Assessed by Cardiometry
Electrical cardiometry (EC) is a non-invasive method of estimating cardiac parameters by measuring changes in thoracic bioimpedance during the cardiac cycle.
- Trial name
- NCT05860010
- Testing
- Epinephrine injection, Dexmedetomidine, Bupivacaine
- Where
- 2 sites in Egypt
- Volunteers
- 39 people
- Sponsor
- Kasr El Aini Hospital