Clinical trials: Pulpitis
Post Operative Endodontic Pain
Reduction of Post-operative Endodontic Pain
To determine the effect of intraligamentary injection of Lornoxicam on the intensity of post-operative endodontic pain in the tooth with symptomatic irreversible pulpitis.
- Trial name
- NCT01480752
- Testing
- Lornoxicam, normal saline, no injection
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Pulpitis - Irreversible
Single Rotary File Pulpectomy in Primary Molars
The aim of this study is to compare the clinical effectiveness of a single rotary file system versus a multiple rotary files system in pulpectomy of primary molars
- Trial name
- NCT06146686
- Testing
- Fanta AF blue rotary files 20 taper 4, Fanta AF baby rotary files 20 , 25 , 30 taper 4
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Efficacy of Combination of Biodentine and Simvastatin as a Pulp Capping Materials in Vital Pulpotomy of Primary Molars
Objective: This study was conducted to evaluate the efficacy of combination of biodentine with simvastatin as a pulpotomy agent for vital primary molars clinically and radiographically.
- Trial name
- NCT05582317
- Testing
- Biodentine, Simvastatin
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Pulpitis - Reversible, Pulpotomy
Clinical and Radiographic Evaluation of Chitosan Versus Formocresol After Vital Pulpotomy of Primary Molars
The goal of this clinical trial is to evaluate whether Chitosan liquid will show similar clinical and radiographical success rate compared to Formocresol when used in vital pulp therapy in primary molars.
- Trial name
- NCT06809478
- Testing
- Pulpotomy using Chitosan liquid, Pulpotomy using Formocresol
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Exposure, Dental, Pulp Disease, Dental
The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy
This study employs saliva-based DNA analysis to investigate the effect of genetic polymorphisms, particularly SNPs in MMP, TIMP, TNF-α, and BMP genes, on the success of vital pulp therapy in permanent teeth with pulpitis…
- Conditions
- Pulp Exposure, Dental, Pulp Disease, Dental, Pulp Caping, Pulpitis
- Trial name
- NCT07130214
- Testing
- Biodentine
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ataturk University
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
high-quality evidence is needed to add to current knowledge and also assess the long-term outcomes for full/complete pulpotomy after carious pulpal exposure in patients with signs and symptoms indicative of irreversible pulpitis
- Trial name
- NCT05726357
- Testing
- vital pulp therapy
- Where
- Egypt
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Pulpectomy, Primary Teeth Indicated for Pulp Therapy
Comparative Evaluation of Pediatric Rotary Files and Hand Files in Primary Molars
The goal of this clinical trial is to evaluate and compare the efficacy of Kedo-Nano Plus rotary files, Kedo-S Square rotary files, and manual K-files for biomechanical preparation during pulpectomy of primary mandibular molars…
- Conditions
- Pulpectomy, Primary Teeth Indicated for Pulp Therapy, Mandibular Molar Teeth With Symptomatic Irreversible Pulpitis
- Trial name
- NCT07702877
- Testing
- Pulpectomy, Kedo-S Square rotary file, Manual K files
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Goa Dental College
Reversible Pulpitis, Dental Pulp Diseases
Success and Color Stability of MTA Pulpotomized Primary Molars: an RCT
Mineral trioxide aggregate has been previously FDA approved as an endodontic filler. Its use in vital teeth has demonstrated significant color change post-treatment leaving it ineffective for esthetic use..
- Trial name
- MTA (NCT02702505)
- Testing
- NeoMTA, ProRoot MTA
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Texas A & M University Baylor College Of Dentistry
Irreversible Pulpitis, Reversible Pulpitis
In Vivo Pulp Thermal Changes During Different Slenderization Techniques
The goal of this study is to learn about the temperature rise inside the living part of a tooth (the pulp) during different ways of removing a small amount of enamel (the hard outer layer of the tooth), a procedure called…
- Conditions
- Irreversible Pulpitis, Reversible Pulpitis, Thermal Injury, Pulp Hyperemia
- Trial name
- IPR (NCT07391124)
- Testing
- High-Speed Air-Driven Drill (Airotor and Bur), Orthodontic IPR Kit (Oscillating System)
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Pulpitis - Reversible, Occlusal Caries
Evaluation of Cytokines Level as an Indicator of Pulp Inflammation and Its Relation to the Success Rates of Pulpotomy in Primary Molars Affected With Proximal Versus Occlusal Decay
pulpotomy will be done I primary molars with occlusal or proximal decay and level of cytokines will be measured as an indicator for pulp inflammation levels
- Conditions
- Pulpitis - Reversible, Occlusal Caries, Proximal Caries
- Trial name
- NCT07171229
- Testing
- Pulpotomy, Measuring Cytokines level
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Pain, Symptomatic Irreversible Pulpitis
Ethyl Chloride Versus 5% Lidocaine for Topical Anesthesia of Oral Mucosa
Local anesthesia in the oral cavity is a pain full experience for the patient. All means should be made to reduce the pain and anxiety of the patient for needle stick procedures.
- Trial name
- NCT05306470
- Testing
- Ethyl chloride, 5% lidocaine gel
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Irreversible Pulpitis, Deep Caries
TheraCal LC Coronal Pulpotomy and MTA Coronal Pulpotomy in Mature Permanent Molars
To evaluate and compare the clinical and radiographic success rate of TheraCal LC and MTA for coronal pulpotomy of mature permanent molar in 9-14 year children.
- Trial name
- NCT05733468
- Testing
- Theracal LC, MTA
- Where
- India
- Volunteers
- 72 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Irreversible Pulpitis
Comparing MTA Pulpotomy to Root Canal Treatment in Management of Permanent Molars With Irreversible Pulpitis in Children
Dental caries, highly prevalent amongst children, can cause pulpitis. Coronal pulpotomy provides an easier, cost-effective, conservative and biologically-driven treatment option compared to endodontic treatment in mature…
- Trial name
- NCT06488131
- Testing
- MTA Pulpotomy, Root Canal Treatment
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pulpitis
Efficacy of Pediatric Rotary File System Versus Hand Instrumentation for Root Canal Preparation in Primary Teeth
The teeth were randomly allocated in two equal groups : Control group (A):- included 20 mandibular primary molars in which pulpectomy were performed by hand instrumentation system using K- File from size 15 to size 35.
- Trial name
- NCT06152354
- Testing
- rotary system, Manual files
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Reversible Pulpitis, Irreversible Pulpitis
Cytokines as Diagnostic Markers of Pulpal Inflammation and Their Impact on the Outcome of Vital Pulp Therapy
intervention eligible patients with teeth diagnosed with reversible or irreversible pulpits will go for vital pulp therapy and the other group will be patients will go for extraction of caries free teeth for orthodontic reasons…
- Trial name
- Pulp Therapy (NCT07261761)
- Testing
- Vital pulp therapy, Extraction, blood sample collection
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Irreversible Pulpitis (Toothache)
Evaluation Of Laser Versus Conventional Pulpotomies In Mature Molar Teeth With Irreversible Pulpitis
this clinical trial is evaluating the outcome of laser assisted pulpotomy compared to conventional pulpotomy in mature teeth with symptomatic irreversible pulpitis (SIP) assessed by CBCT followed by automated segmentation using…
- Trial name
- NCT07287709
- Testing
- Diode laser, Sodium Hypochlorite Solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Rana Hegaz
Reversible Pulpitis, Irreversible Pulpitis
Evaluation of Pulpal Biomarkers in Vital Pulp Therapy
This prospective clinical study aims to evaluate the association between the levels of selected pulpal biomarkers and the clinical success of vital pulp therapy in permanent teeth.
- Conditions
- Reversible Pulpitis, Irreversible Pulpitis, Vital Pulp Therapy, Dental Pulp Diseases
- Trial name
- NCT07073573
- Testing
- Vital pulp therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- ertuğrul karataş
Pulpitis - Irreversible
Evaluation of Lesion Sterilization and Tissue Repair Techniques Versus Pulpectomy in Primary Molars With Inflammed Pulp
Group I (Experimental group I): Lesion Sterilization and Tissue Repair with radicular instrumentation. Coronal and accessible radicular pulp tissue are extirpated using rotary files.
- Trial name
- NCT05336682
- Testing
- Lesion Sterilization and Tissue Repair with radicular instrumentation, Lesion Sterilization and Tissue Repair without radicular instrumentation, Conventional pulpectomy
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis, Dental Pulp Disease
Success Rate Evaluation of Miniature Pulpotomy With MTA in Primary Molars
The purpose of this study is to evaluate the clinical and radiographic success rate of Miniature pulpotomy with Mineral Trioxide Aggregate (MTA) in primary molars.
- Conditions
- Pulpitis, Dental Pulp Disease, Tooth Diseases
- Trial name
- NCT02286648
- Testing
- Formocresol, Mineral Trioxide Aggregate
- Where
- 2 sites in Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Pulp Disease, Dental, Pulpitis
Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker
This prospective controlled clinical trial investigates whether metabolic biomarkers measured in pulpal blood at the time of carious pulp exposure can predict the 12-month outcomes of vital pulp treatment in symptomatic permanent…
- Conditions
- Pulp Disease, Dental, Pulpitis, Reversible Pulpitis, Irreversible Pulpitis (Toothache)
- Trial name
- NCT07452614
- Testing
- vital pulp treatment
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abeer Ghalib Abdul-khaliq